product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
GLI-2 (C-10) Antibody
catalog :
sc-271786
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-10
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 9c
Duan S, Sawyer T, Sontz R, Wieland B, Diaz A, Merchant J. GFAP-directed Inactivation of Men1 Exploits Glial Cell Plasticity in Favor of Neuroendocrine Reprogramming. Cell Mol Gastroenterol Hepatol. 2022;14:1025-1051 pubmed publisher
  • western blot; mouse; 0.2 ug/ml; loading ...; fig 3c
Wu X, Shu L, Zhang Z, Li J, Zong J, Cheong L, et al. Adipocyte Fatty Acid Binding Protein Promotes the Onset and Progression of Liver Fibrosis via Mediating the Crosstalk between Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells. Adv Sci (Weinh). 2021;8:e2003721 pubmed publisher
  • western blot; human; loading ...; fig 5d, 5e
Cui H, Yu W, Yu M, Luo Y, Yang M, Cong R, et al. GPR126 regulates colorectal cancer cell proliferation by mediating HDAC2 and GLI2 expression. Cancer Sci. 2021;112:1798-1810 pubmed publisher
  • western blot; human; loading ...; fig 7f
  • western blot; rat; loading ...; fig s7a
Li S, Wei Z, Li G, Zhang Q, Niu S, Xu D, et al. Silica Perturbs Primary Cilia and Causes Myofibroblast Differentiation during Silicosis by Reduction of the KIF3A-Repressor GLI3 Complex. Theranostics. 2020;10:1719-1732 pubmed publisher
  • western blot; human; loading ...; fig 3h
Kramer M, Markart P, Drakopanagiotakis F, Mamazhakypov A, Schaefer L, Didiasova M, et al. Pirfenidone inhibits motility of NSCLC cells by interfering with the urokinase system. Cell Signal. 2020;65:109432 pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; fig 2g
Drannik A, MARTIN J, Peterson R, Ma X, Jiang F, Turnbull J. Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function. PLoS ONE. 2017;12:e0171668 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s9c
Pattabiraman D, Bierie B, Kober K, Thiru P, Krall J, Zill C, et al. Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability. Science. 2016;351:aad3680 pubmed publisher
  • chromatin immunoprecipitation; human; fig 5
Vlčková K, Ondrušová L, Vachtenheim J, Réda J, Dundr P, Zadinová M, et al. Survivin, a novel target of the Hedgehog/GLI signaling pathway in human tumor cells. Cell Death Dis. 2016;7:e2048 pubmed publisher
  • western blot; human; fig 4a
Inaguma S, Ito H, Riku M, Ikeda H, Kasai K. Addiction of pancreatic cancer cells to zinc-finger transcription factor ZIC2. Oncotarget. 2015;6:28257-68 pubmed publisher
  • western blot; human; fig 4b
  • western blot; mouse; loading ...; fig 1a
Bora Singhal N, Perumal D, Nguyen J, Chellappan S. Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer. Neoplasia. 2015;17:538-51 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400
  • western blot; mouse; 1:200
Liu J, Bain L. Arsenic inhibits hedgehog signaling during P19 cell differentiation. Toxicol Appl Pharmacol. 2014;281:243-53 pubmed publisher
Kowolik C, Lin M, Xie J, Overman L, Horne D. Attenuation of hedgehog/GLI signaling by NT1721 extends survival in pancreatic cancer. J Exp Clin Cancer Res. 2019;38:431 pubmed publisher
Zhou F, Huang D, Li Y, Hu G, Rao H, Lu Q, et al. Nek2A/SuFu feedback loop regulates Gli-mediated Hedgehog signaling pathway. Int J Oncol. 2017;50:373-380 pubmed publisher
Coni S, Antonucci L, D Amico D, Di Magno L, Infante P, De Smaele E, et al. Gli2 acetylation at lysine 757 regulates hedgehog-dependent transcriptional output by preventing its promoter occupancy. PLoS ONE. 2013;8:e65718 pubmed publisher
product information
Catalog Number :
sc-271786
Product Name :
GLI-2 (C-10) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
C-10
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
GLI-2
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA