product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
cyclin A (B-8) Antibody
catalog :
sc-271682
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-8
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2a
Yoshida A, Bu Y, Qie S, Wrangle J, Camp E, Hazard E, et al. SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors. Sci Adv. 2019;5:eaax6352 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 4a
Bigot N, Day M, Baldock R, Watts F, Oliver A, Pearl L. Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint. elife. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig 6
Lv M, Li Y, Tian X, Dai S, Sun J, Jin G, et al. Lentivirus-mediated knockdown of NLK inhibits small-cell lung cancer growth and metastasis. Drug Des Devel Ther. 2016;10:3737-3746 pubmed
  • immunocytochemistry; human; 1:100; fig 1
Kuo C, Li X, Stark J, Shih H, Ann D. RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner. Cell Cycle. 2016;15:787-98 pubmed publisher
  • western blot; human; fig 3
Borges K, Arboleda V, Vilain E. Mutations in the PCNA-binding site of CDKN1C inhibit cell proliferation by impairing the entry into S phase. Cell Div. 2015;10:2 pubmed publisher
Chang Y, Lin K, Baxley R, Durrett W, Wang L, Stojkova O, et al. RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication. Open Biol. 2023;13:230068 pubmed publisher
Wavelet Vermuse C, Odnokoz O, Xue Y, Lu X, Cristofanilli M, Wan Y. CDC20-Mediated hnRNPU Ubiquitination Regulates Chromatin Condensation and Anti-Cancer Drug Response. Cancers (Basel). 2022;14: pubmed publisher
Zhang X, Sun Y, Cheng S, Yao Y, Hua X, Shi Y, et al. CDK6 increases glycolysis and suppresses autophagy by mTORC1-HK2 pathway activation in cervical cancer cells. Cell Cycle. 2022;21:984-1002 pubmed publisher
Greco S, Ayer S, Guiro K, Sinha G, Donnelly R, El Far M, et al. Restoration of aged hematopoietic cells by their young counterparts through instructive microvesicles release. Aging (Albany NY). 2021;13:23981-24016 pubmed publisher
Cuella Martin R, Hayward S, Fan X, Chen X, Huang J, Taglialatela A, et al. Functional interrogation of DNA damage response variants with base editing screens. Cell. 2021;184:1081-1097.e19 pubmed publisher
Chappidi N, Nascakova Z, Boleslavska B, Zellweger R, Isik E, Andrs M, et al. Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops. Mol Cell. 2019;: pubmed publisher
Li J, Dang N, Martínez López N, Jowsey P, Huang D, Lightowlers R, et al. M2I-1 disrupts the in vivo interaction between CDC20 and MAD2 and increases the sensitivities of cancer cell lines to anti-mitotic drugs via MCL-1s. Cell Div. 2019;14:5 pubmed publisher
Chu Z, Zhang X, Li Q, Hu G, Lian C, Geng S. CDC20 contributes to the development of human cutaneous squamous cell carcinoma through the Wnt/β‑catenin signaling pathway. Int J Oncol. 2019;54:1534-1544 pubmed publisher
Knudsen E, Kumarasamy V, Ruiz A, Sivinski J, Chung S, Grant A, et al. Cell cycle plasticity driven by MTOR signaling: integral resistance to CDK4/6 inhibition in patient-derived models of pancreatic cancer. Oncogene. 2019;38:3355-3370 pubmed publisher
Di Marco S, Hasanova Z, Kanagaraj R, Chappidi N, Altmannova V, Menon S, et al. RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis. Mol Cell. 2017;66:658-671.e8 pubmed publisher
product information
Catalog Number :
sc-271682
Product Name :
cyclin A (B-8) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
B-8
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
cyclin A
Specificity :
human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA