product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
HMGCR (C-1) Antibody
catalog :
sc-271595
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-1
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2c
Göbel A, Breining D, Rauner M, Hofbauer L, Rachner T. Induction of 3-hydroxy-3-methylglutaryl-CoA reductase mediates statin resistance in breast cancer cells. Cell Death Dis. 2019;10:91 pubmed publisher
  • western blot; mouse; loading ...; fig 5e
Moon S, Huang C, Houlihan S, Regunath K, Freed Pastor W, Morris J, et al. p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression. Cell. 2019;176:564-580.e19 pubmed publisher
  • western blot; human; fig 1
Laezza C, D Alessandro A, Di Croce L, Picardi P, Ciaglia E, Pisanti S, et al. p53 regulates the mevalonate pathway in human glioblastoma multiforme. Cell Death Dis. 2015;6:e1909 pubmed publisher
  • western blot; human; 1:1000; fig 3
Sharon C, Baranwal S, Patel N, Rodriguez Agudo D, Pandak W, Majumdar A, et al. Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. Oncotarget. 2015;6:15332-47 pubmed
Centonze G, Natalini D, Grasso S, Morellato A, Salemme V, Piccolantonio A, et al. p140Cap modulates the mevalonate pathway decreasing cell migration and enhancing drug sensitivity in breast cancer cells. Cell Death Dis. 2023;14:849 pubmed publisher
Greenaway J, Virtanen C, Osz K, Revay T, Hardy D, Shepherd T, et al. Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer. Oncotarget. 2016;7:47343-47365 pubmed publisher
product information
Catalog Number :
sc-271595
Product Name :
HMGCR (C-1) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
C-1
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
HMGCR
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA