product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
DRP1 (C-5) Antibody
catalog :
sc-271583
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-5
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:500; fig 6b
Wang Y, Xu Y, Zhou K, Zhang S, Wang Y, Li T, et al. Autophagy Inhibition Reduces Irradiation-Induced Subcortical White Matter Injury Not by Reducing Inflammation, but by Increasing Mitochondrial Fusion and Inhibiting Mitochondrial Fission. Mol Neurobiol. 2022;59:1199-1213 pubmed publisher
  • western blot; mouse; loading ...; fig 1e
Yoon Y, Go G, Yoon S, Lim J, Lee G, Lee J, et al. Melatonin Treatment Improves Renal Fibrosis via miR-4516/SIAH3/PINK1 Axis. Cells. 2021;10: pubmed publisher
  • western blot; human; 1:500; loading ...; fig 8f
He Y, Kan W, Li Y, Hao Y, Huang A, Gu H, et al. A potent and selective small molecule inhibitor of myoferlin attenuates colorectal cancer progression. Clin Transl Med. 2021;11:e289 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3b
Chen Z, Zhou Q, Liu C, Zeng Y, Yuan S. Klotho deficiency aggravates diabetes-induced podocyte injury due to DNA damage caused by mitochondrial dysfunction. Int J Med Sci. 2020;17:2763-2772 pubmed publisher
  • western blot; human; loading ...; fig 6a
Rademaker G, Hennequière V, Brohée L, Nokin M, Lovinfosse P, Durieux F, et al. Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness. Oncogene. 2018;37:4398-4412 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b
Cooper H, Yang Y, Ylikallio E, Khairullin R, Woldegebriel R, Lin K, et al. ATPase-deficient mitochondrial inner membrane protein ATAD3A disturbs mitochondrial dynamics in dominant hereditary spastic paraplegia. Hum Mol Genet. 2017;26:1432-1443 pubmed publisher
  • western blot; human; fig 4
Suzuki Karasaki Y, Fujiwara K, Saito K, Suzuki Karasaki M, Ochiai T, Soma M. Distinct effects of TRAIL on the mitochondrial network in human cancer cells and normal cells: role of plasma membrane depolarization. Oncotarget. 2015;6:21572-88 pubmed
  • western blot; human
  • western blot; rat
Xu S, Pi H, Chen Y, Zhang N, Guo P, Lu Y, et al. Cadmium induced Drp1-dependent mitochondrial fragmentation by disturbing calcium homeostasis in its hepatotoxicity. Cell Death Dis. 2013;4:e540 pubmed publisher
  • immunocytochemistry; mouse
  • western blot; mouse; 1:1000
Faccenda D, Tan C, Seraphim A, Duchen M, Campanella M. IF1 limits the apoptotic-signalling cascade by preventing mitochondrial remodelling. Cell Death Differ. 2013;20:686-97 pubmed publisher
Lee H, Gu M, Kim Y, Lee J, Lee S, Choi I, et al. Glyoxal-Lysine Dimer, an Advanced Glycation End Product, Induces Oxidative Damage and Inflammatory Response by Interacting with RAGE. Antioxidants (Basel). 2021;10: pubmed publisher
Singlár Z, Szentesi P, Fodor J, Angyal Á, Csernoch L, Sztretye M. Assessing the Potential of Nutraceuticals as Geroprotectors on Muscle Performance and Cognition in Aging Mice. Antioxidants (Basel). 2021;10: pubmed publisher
Sulkshane P, Ram J, Thakur A, Reis N, Kleifeld O, Glickman M. Ubiquitination and receptor-mediated mitophagy converge to eliminate oxidation-damaged mitochondria during hypoxia. Redox Biol. 2021;45:102047 pubmed publisher
Yin K, Lee J, Liu Z, Kim H, Martin D, Wu D, et al. Mitophagy protein PINK1 suppresses colon tumor growth by metabolic reprogramming via p53 activation and reducing acetyl-CoA production. Cell Death Differ. 2021;28:2421-2435 pubmed publisher
Padder R, Bhat Z, Ahmad Z, Singh N, Husain M. DRP1 Promotes BRAFV600E-Driven Tumor Progression and Metabolic Reprogramming in Colorectal Cancer. Front Oncol. 2020;10:592130 pubmed publisher
Elsherbini A, Kirov A, Dinkins M, Wang G, Qin H, Zhu Z, et al. Association of Aβ with ceramide-enriched astrosomes mediates Aβ neurotoxicity. Acta Neuropathol Commun. 2020;8:60 pubmed publisher
Chauhan S, Toth R, Jensen C, Casillas A, Kashatus D, Warfel N. PIM kinases alter mitochondrial dynamics and chemosensitivity in lung cancer. Oncogene. 2020;39:2597-2611 pubmed publisher
Lin S, Huang C, Gunda V, Sun J, Chellappan S, Li Z, et al. Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments. Cell Rep. 2019;28:2824-2836.e8 pubmed publisher
Neary M, Ng K, Ludtmann M, Hall A, Piotrowska I, Ong S, et al. Hypoxia signaling controls postnatal changes in cardiac mitochondrial morphology and function. J Mol Cell Cardiol. 2014;74:340-52 pubmed publisher
product information
Catalog Number :
sc-271583
Product Name :
DRP1 (C-5) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
C-5
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
DRP1
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA