product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
ASC (F-9) Antibody
catalog :
sc-271054
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
F-9
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 4n
Wang W, Hu D, Wu C, Feng Y, Li A, Liu W, et al. STING promotes NLRP3 localization in ER and facilitates NLRP3 deubiquitination to activate the inflammasome upon HSV-1 infection. PLoS Pathog. 2020;16:e1008335 pubmed publisher
  • western blot; rat; loading ...; fig 4a
Qin W, Wu X, Jia Y, Tong X, Guo C, Chen D, et al. Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma. Biomed Pharmacother. 2019;118:109188 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 1b
Bednash J, Weathington N, Londino J, Rojas M, Gulick D, Fort R, et al. Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity. Nat Commun. 2017;8:15203 pubmed publisher
  • western blot; mouse; loading ...; fig 5e
Wei C, Wang Y, Du Z, Guan K, Cao Y, Yang H, et al. The Yersinia Type III secretion effector YopM Is an E3 ubiquitin ligase that induced necrotic cell death by targeting NLRP3. Cell Death Dis. 2016;7:e2519 pubmed publisher
  • western blot; human; fig 1
Choulaki C, Papadaki G, Repa A, Kampouraki E, Kambas K, Ritis K, et al. Enhanced activity of NLRP3 inflammasome in peripheral blood cells of patients with active rheumatoid arthritis. Arthritis Res Ther. 2015;17:257 pubmed publisher
  • immunoprecipitation; human; 1:1000; fig 4
  • western blot; human; 1:1000; fig 4
Woolery K, Mohamed M, Linger R, Dobrinski K, Roman J, Kruk P. BRCA1 185delAG Mutation Enhances Interleukin-1β Expression in Ovarian Surface Epithelial Cells. Biomed Res Int. 2015;2015:652017 pubmed publisher
  • western blot; human
Ataide M, Andrade W, Zamboni D, Wang D, Souza M, Franklin B, et al. Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection. PLoS Pathog. 2014;10:e1003885 pubmed publisher
Cordaro M, Salinaro A, Siracusa R, D Amico R, Impellizzeri D, Scuto M, et al. Key Mechanisms and Potential Implications of Hericium erinaceus in NLRP3 Inflammasome Activation by Reactive Oxygen Species during Alzheimer's Disease. Antioxidants (Basel). 2021;10: pubmed publisher
Wang W, Hu D, Feng Y, Wu C, Song Y, Liu W, et al. Paxillin mediates ATP-induced activation of P2X7 receptor and NLRP3 inflammasome. BMC Biol. 2020;18:182 pubmed publisher
Du R, Lu M, Wang C, Ding J, Wu G, Hu G. The pore-forming subunit Kir6.1 of the K-ATP channel negatively regulates the NLRP3 inflammasome to control insulin resistance by interacting with NLRP3. Exp Mol Med. 2019;51:92 pubmed publisher
Wang W, Li G, De Wu -, Luo Z, Pan P, Tian M, et al. Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion. Nat Commun. 2018;9:106 pubmed publisher
Guo W, Liu W, Chen Z, Gu Y, Peng S, Shen L, et al. Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis. Nat Commun. 2017;8:2168 pubmed publisher
Verway M, Bouttier M, Wang T, Carrier M, Calderon M, An B, et al. Vitamin D induces interleukin-1? expression: paracrine macrophage epithelial signaling controls M. tuberculosis infection. PLoS Pathog. 2013;9:e1003407 pubmed publisher
Zhang X, Cheng Y, Xiong Y, Ye C, Zheng H, Sun H, et al. Enterohemorrhagic Escherichia coli specific enterohemolysin induced IL-1? in human macrophages and EHEC-induced IL-1? required activation of NLRP3 inflammasome. PLoS ONE. 2012;7:e50288 pubmed publisher
product information
Catalog Number :
sc-271054
Product Name :
ASC (F-9) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
F-9
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
ASC
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA