product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
GATA-3 (HG3-31) AC
catalog :
sc-268 AC
quantity :
500 µg/ml, 25% ag
price :
416 USD
clonality :
monoclonal
host :
mouse
conjugate :
agarose
clone name :
HG3-31
reactivity :
human, mouse, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 26
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...; fig 4a
Kim J, Villadsen R. Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland. J Histochem Cytochem. 2018;66:879-888 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 7b
O Brien T, Bao K, Dell aringa M, Ang W, Abraham S, Reinhardt R. Cytokine expression by invariant natural killer T cells is tightly regulated throughout development and settings of type-2 inflammation. Mucosal Immunol. 2016;9:597-609 pubmed publisher
  • western blot; human; fig 5
Baraut J, Farge D, Jean Louis F, Masse I, Grigore E, Arruda L, et al. Transforming growth factor-β increases interleukin-13 synthesis via GATA-3 transcription factor in T-lymphocytes from patients with systemic sclerosis. Arthritis Res Ther. 2015;17:196 pubmed publisher
  • western blot; mouse
Bruchard M, Rebé C, Derangère V, Togbé D, Ryffel B, Boidot R, et al. The receptor NLRP3 is a transcriptional regulator of TH2 differentiation. Nat Immunol. 2015;16:859-70 pubmed publisher
  • western blot; mouse; 1:200; fig 4
Castiglioni A, Corna G, Rigamonti E, Basso V, Vezzoli M, Monno A, et al. FOXP3+ T Cells Recruited to Sites of Sterile Skeletal Muscle Injury Regulate the Fate of Satellite Cells and Guide Effective Tissue Regeneration. PLoS ONE. 2015;10:e0128094 pubmed publisher
  • immunohistochemistry; human
Gromova I, Gromov P, Honma N, Kumar S, Rimm D, Talman M, et al. High level PHGDH expression in breast is predominantly associated with keratin 5-positive cell lineage independently of malignancy. Mol Oncol. 2015;9:1636-54 pubmed publisher
  • immunocytochemistry; mouse
  • western blot; mouse
  • western blot; human
Kitagawa K, Shibata K, Matsumoto A, Matsumoto M, Ohhata T, Nakayama K, et al. Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development. Mol Cell Biol. 2014;34:2732-44 pubmed
  • immunohistochemistry - paraffin section; human; 1:100
Ordonez N, Sahin A. Diagnostic utility of immunohistochemistry in distinguishing between epithelioid pleural mesotheliomas and breast carcinomas: a comparative study. Hum Pathol. 2014;45:1529-40 pubmed publisher
  • immunocytochemistry; human; 1:250
  • immunohistochemistry; human; 1:250
Balk Møller E, Kim J, Hopkinson B, Timmermans Wielenga V, Petersen O, Villadsen R. A marker of endocrine receptor-positive cells, CEACAM6, is shared by two major classes of breast cancer: luminal and HER2-enriched. Am J Pathol. 2014;184:1198-208 pubmed publisher
  • western blot; human
Cyr A, Kulak M, Park J, Bogachek M, Spanheimer P, Woodfield G, et al. TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis. Oncogene. 2015;34:436-44 pubmed publisher
  • immunohistochemistry; chicken; 1:200
Warchol M, Speck J. Expression of GATA3 and tenascin in the avian vestibular maculae: normative patterns and changes during sensory regeneration. J Comp Neurol. 2007;500:646-57 pubmed
Hertweck A, Vila de Mucha M, Barber P, Dagil R, Porter H, Ramos A, et al. The TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes. Nucleic Acids Res. 2022;50:4557-4573 pubmed publisher
Naik A, Byrd A, Lucander A, Krangel M. Hierarchical assembly and disassembly of a transcriptionally active RAG locus in CD4+CD8+ thymocytes. J Exp Med. 2019;216:231-243 pubmed publisher
Yamamoto T, Endo Y, Onodera A, Hirahara K, Asou H, Nakajima T, et al. DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells. Nat Commun. 2018;9:4231 pubmed publisher
Yang Y, Liu B, Xu J, Wang J, Wu J, Shi C, et al. Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell. 2017;169:243-257.e25 pubmed publisher
Sada A, Jain P, Wang S, Leung E, Tumbar T. Slc1a3-CreER as a Targeting Tool for the K6+ Epithelial Stem Cell Niche and its Precursors during Mouse Hair Follicle Cycle. J Invest Dermatol. 2017;137:1569-1571 pubmed publisher
Li Y, Lu Y, Wang S, Han Z, Zhu F, Ni Y, et al. USP21 prevents the generation of T-helper-1-like Treg cells. Nat Commun. 2016;7:13559 pubmed publisher
Gaughan L, Stockley J, Coffey K, O Neill D, Jones D, Wade M, et al. KDM4B is a master regulator of the estrogen receptor signalling cascade. Nucleic Acids Res. 2013;41:6892-904 pubmed publisher
Frietze S, Wang R, Yao L, Tak Y, Ye Z, Gaddis M, et al. Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3. Genome Biol. 2012;13:R52 pubmed publisher
Chang W, Lin Z, Kulessa H, Hebert J, Hogan B, Wu D. Bmp4 is essential for the formation of the vestibular apparatus that detects angular head movements. PLoS Genet. 2008;4:e1000050 pubmed publisher
Naoe Y, Setoguchi R, Akiyama K, Muroi S, Kuroda M, Hatam F, et al. Repression of interleukin-4 in T helper type 1 cells by Runx/Cbf beta binding to the Il4 silencer. J Exp Med. 2007;204:1749-55 pubmed
Abba M, Nunez M, Colussi A, Croce M, Segal Eiras A, Aldaz C. GATA3 protein as a MUC1 transcriptional regulator in breast cancer cells. Breast Cancer Res. 2006;8:R64 pubmed
Yamane H, Zhu J, Paul W. Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment. J Exp Med. 2005;202:793-804 pubmed
Bocek P, Foucras G, Paul W. Interferon gamma enhances both in vitro and in vivo priming of CD4+ T cells for IL-4 production. J Exp Med. 2004;199:1619-30 pubmed
Komine O, Hayashi K, Natsume W, Watanabe T, Seki Y, Seki N, et al. The Runx1 transcription factor inhibits the differentiation of naive CD4+ T cells into the Th2 lineage by repressing GATA3 expression. J Exp Med. 2003;198:51-61 pubmed
Zhou M, Ouyang W, Gong Q, Katz S, White J, Orkin S, et al. Friend of GATA-1 represses GATA-3-dependent activity in CD4+ T cells. J Exp Med. 2001;194:1461-71 pubmed
product information
Catalog Number :
sc-268 AC
Product Name :
GATA-3 (HG3-31) AC
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Conjugation :
agarose
Clone Name :
HG3-31
Isotype :
IgG1
Size :
500 µg/ml, 25% ag
List Price :
416 USD
Immunogen :
GATA-3
Specificity :
mouse, rat, human, avian
Uses :
IP
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA