Beziat V, Tavernier S, Chen Y, Ma C, Materna M, Laurence A, et al. Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome. J Exp Med. 2020;217: pubmed publisher

Martínez González L, Rodríguez Cueto C, Cabezudo D, Bartolomé F, Andrés Benito P, Ferrer I, et al. Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1δ kinase inhibitor treatment. Sci Rep. 2020;10:4449 pubmed publisher

Nakai A, Fujimoto J, Miyata H, Stumm R, Narazaki M, Schulz S, et al. The COMMD3/8 complex determines GRK6 specificity for chemoattractant receptors. J Exp Med. 2019;: pubmed publisher

Rausch V, Bostrom J, Park J, Bravo I, Feng Y, Hay D, et al. The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae. Curr Biol. 2019;29:242-255.e6 pubmed publisher

Urtishak K, Wang L, Culjkovic Kraljacic B, Davenport J, Porazzi P, Vincent T, et al. Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia. Oncogene. 2019;38:2241-2262 pubmed publisher

Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, de Tullio P, et al. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 2018;558:605-609 pubmed publisher

Kralovicova J, Sevcikova I, Stejskalova E, Obuca M, Hiller M, Stanek D, et al. PUF60-activated exons uncover altered 3' splice-site selection by germline missense mutations in a single RRM. Nucleic Acids Res. 2018;46:6166-6187 pubmed publisher

Parikh V, Liu J, Shang C, Woods C, Chang A, Zhao M, et al. Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition. Am J Physiol Heart Circ Physiol. 2018;315:H348-H356 pubmed publisher

François C, Petit F, Giton F, Gougeon A, Ravel C, Magre S, et al. A novel action of follicle-stimulating hormone in the ovary promotes estradiol production without inducing excessive follicular growth before puberty. Sci Rep. 2017;7:46222 pubmed publisher

Wizeman J, Nicholas A, Ishigami A, Mohan R. Citrullination of glial intermediate filaments is an early response in retinal injury. Mol Vis. 2016;22:1137-1155 pubmed

Weikel K, Cacicedo J, Ruderman N, Ido Y. Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells. Biosci Rep. 2016;36: pubmed publisher

Kim H, Choi M, Inn K, Kim B. Inhibition of HIV-1 reactivation by a telomerase-derived peptide in a HSP90-dependent manner. Sci Rep. 2016;6:28896 pubmed publisher

Tobita T, Guzman Lepe J, Takeishi K, Nakao T, Wang Y, Meng F, et al. SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids. PLoS ONE. 2016;11:e0149344 pubmed publisher

Preet R, Siddharth S, Satapathy S, Das S, Nayak A, Das D, et al. Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade. Biochem Pharmacol. 2016;105:23-33 pubmed publisher

Wang B, Ma A, Zhang L, Jin W, Qian Y, Xu G, et al. POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation. Nat Commun. 2015;6:8704 pubmed publisher

Boczek T, Lisek M, Ferenc B, Wiktorska M, Ivchevska I, Zylinska L. Region-specific effects of repeated ketamine administration on the presynaptic GABAergic neurochemistry in rat brain. Neurochem Int. 2015;91:13-25 pubmed publisher

Qin J, Zhou Z, Chen W, Wang C, Zhang H, Ge G, et al. BAP1 promotes breast cancer cell proliferation and metastasis by deubiquitinating KLF5. Nat Commun. 2015;6:8471 pubmed publisher

Zhang J, Tripathi D, Jing J, Alexander A, Kim J, Powell R, et al. ATM functions at the peroxisome to induce pexophagy in response to ROS. Nat Cell Biol. 2015;17:1259-1269 pubmed publisher

Chung H, Jacobs C, Huo Y, Yang J, Krumm S, Plemper R, et al. Tunable and reversible drug control of protein production via a self-excising degron. Nat Chem Biol. 2015;11:713-20 pubmed publisher

Hedberg Oldfors C, Dios D, Linder A, Visuttijai K, Samuelson E, Karlsson S, et al. Analysis of an independent tumor suppressor locus telomeric to Tp53 suggested Inpp5k and Myo1c as novel tumor suppressor gene candidates in this region. BMC Genet. 2015;16:80 pubmed publisher

Bangs F, Schrode N, Hadjantonakis A, Anderson K. Lineage specificity of primary cilia in the mouse embryo. Nat Cell Biol. 2015;17:113-22 pubmed publisher

Chirasani V, Khan M, Malavade J, Dokholyan N, Hoffman B, Campbell S. Molecular basis and cellular functions of vinculin-actin directional catch bonding. Nat Commun. 2023;14:8300 pubmed publisher

Khan R, Oskouian B, Lee J, Hodgin J, Yang Y, Tassew G, et al. AAV-SPL 2.0, a Modified Adeno-Associated Virus Gene Therapy Agent for the Treatment of Sphingosine Phosphate Lyase Insufficiency Syndrome. Int J Mol Sci. 2023;24: pubmed publisher

Park J, Lee D, Kim D. Redefining the role of AMPK in autophagy and the energy stress response. Nat Commun. 2023;14:2994 pubmed publisher

Isei M, Girardi P, Rodwell Bullock J, Nehrke K, Johnson G. Site-specific phosphorylation of tau impacts mitochondrial biology and response to stressors. bioRxiv. 2023;: pubmed publisher

Borges J, S xe6 tra R, Volchuk A, Bugge M, Devant P, Sporsheim B, et al. Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death. elife. 2022;11: pubmed publisher

Kim S, Leong A, Kim M, Yang H. CDK4/6 initiates Rb inactivation and CDK2 activity coordinates cell-cycle commitment and G1/S transition. Sci Rep. 2022;12:16810 pubmed publisher

Liu W, Ma Z, Wu Y, Yuan C, Zhang Y, Liang Z, et al. MST4 negatively regulates type I interferons production via targeting MAVS-mediated pathway. Cell Commun Signal. 2022;20:103 pubmed publisher

Wrobel M, Cendrowski J, Szymańska E, Grębowicz Maciukiewicz M, Budick Harmelin N, Macias M, et al. ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway. Life Sci Alliance. 2022;5: pubmed publisher

Tseng H, Zeng Y, Lin Y, Huang J, Lin C, Lee M, et al. A novel AMPK activator shows therapeutic potential in hepatocellular carcinoma by suppressing HIF1α-mediated aerobic glycolysis. Mol Oncol. 2022;16:2274-2294 pubmed publisher

Sun T, Ding C, Zhang Y, Zhang Y, Lin C, Wu J, et al. MESH1 knockdown triggers proliferation arrest through TAZ repression. Cell Death Dis. 2022;13:221 pubmed publisher

Steurer C, Kerschbaum S, Wegrostek C, Gabriel S, Hallaj A, Ortner V, et al. Quantitative Comparison of HSF1 Activators. Mol Biotechnol. 2022;64:873-887 pubmed publisher

Kim H, Jang S, Lee Y. The m6A(m)-independent role of FTO in regulating WNT signaling pathways. Life Sci Alliance. 2022;5: pubmed publisher

Chen Z, Li J, Zhu S, Li Z, Yu J, Wu J, et al. Harmine reinforces the effects of regorafenib on suppressing cell proliferation and inducing apoptosis in liver cancer cells. Exp Ther Med. 2022;23:209 pubmed publisher

Lee M, Nagashima K, Yoon J, Sun J, Wang Z, Carpenter C, et al. CEP97 phosphorylation by Dyrk1a is critical for centriole separation during multiciliogenesis. J Cell Biol. 2022;221: pubmed publisher

Hersh J, Condor Capcha J, Iansen Irion C, Lambert G, Noguera M, Singh M, et al. Peptide-Functionalized Dendrimer Nanocarriers for Targeted Microdystrophin Gene Delivery. Pharmaceutics. 2021;13: pubmed publisher

Zhu B, Finch Edmondson M, Leong K, Zhang X, V M, Lin Q, et al. LncRNA SFTA1P mediates positive feedback regulation of the Hippo-YAP/TAZ signaling pathway in non-small cell lung cancer. Cell Death Discov. 2021;7:369 pubmed publisher

Gerassimovich Y, Miladinovski Bangall S, Bridges K, Boateng L, Ball L, Valafar H, et al. Proximity-dependent biotinylation detects associations between SARS coronavirus nonstructural protein 1 and stress granule-associated proteins. J Biol Chem. 2021;297:101399 pubmed publisher

McCann J, Vasilevskaya I, McNair C, Gallagher P, Neupane N, de Leeuw R, et al. Mutant p53 elicits context-dependent pro-tumorigenic phenotypes. Oncogene. 2021;: pubmed publisher

Palikaras K, Achanta K, Choi S, Akbari M, Bohr V. Alteration of mitochondrial homeostasis is an early event in a C. elegans model of human tauopathy. Aging (Albany NY). 2021;13:23876-23894 pubmed publisher

Martinez Bernabe T, Sastre Serra J, Ciobu N, Oliver J, Pons D, Roca P. Estrogen Receptor Beta (ERβ) Maintains Mitochondrial Network Regulating Invasiveness in an Obesity-Related Inflammation Condition in Breast Cancer. Antioxidants (Basel). 2021;10: pubmed publisher

He L, Huang Z, Huang K, Chen R, Nguyen N, Wang R, et al. Optogenetic Control of Non-Apoptotic Cell Death. Adv Sci (Weinh). 2021;8:2100424 pubmed publisher

Alvarez Suarez P, Nowak N, Protasiuk Filipunas A, Yamazaki H, Proszynski T, Gawor M. Drebrin Regulates Acetylcholine Receptor Clustering and Organization of Microtubules at the Postsynaptic Machinery. Int J Mol Sci. 2021;22: pubmed publisher

Zhao X, Liberti R, Jian J, Fu W, Hettinghouse A, Sun Y, et al. Progranulin associates with Rab2 and is involved in autophagosome-lysosome fusion in Gaucher disease. J Mol Med (Berl). 2021;99:1639-1654 pubmed publisher

al Yacoub N, Colak D, Mahmoud S, Hammonds M, Muhammed K, Al Harazi O, et al. Mutation in FBXO32 causes dilated cardiomyopathy through up-regulation of ER-stress mediated apoptosis. Commun Biol. 2021;4:884 pubmed publisher

Yue F, Jiang W, Ku A, Young A, Zhang W, Souto E, et al. A Wnt-Independent LGR4-EGFR Signaling Axis in Cancer Metastasis. Cancer Res. 2021;: pubmed publisher

Janda E, Martino C, Riillo C, Parafati M, Lascala A, Mollace V, et al. Apigenin and Luteolin Regulate Autophagy by Targeting NRH-Quinone Oxidoreductase 2 in Liver Cells. Antioxidants (Basel). 2021;10: pubmed publisher

Silwal P, Kim J, Jeon S, Lee J, Kim Y, Kim Y, et al. Mitofusin-2 boosts innate immunity through the maintenance of aerobic glycolysis and activation of xenophagy in mice. Commun Biol. 2021;4:548 pubmed publisher

Kim H, Jang S. RNA m6A Methyltransferase Mettl3 Regulates Spatial Neural Patterning in Xenopus laevis. Mol Cell Biol. 2021;41:e0010421 pubmed publisher

Dinh T, Iseki H, Mizuno S, Iijima Mizuno S, Tanimoto Y, Daitoku Y, et al. Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway. elife. 2021;10: pubmed publisher

Gu Z, Liu Y, Zhang Y, Cao H, Lyu J, Wang X, et al. Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia. Nat Genet. 2021;53:672-682 pubmed publisher

Wang Y, Luo M, Mao X, Shi X, Liu X. Targeted Delivery of Salusin-α into Rabbit Carotid Arterial Endothelium Using SonoVue. J Ultrasound Med. 2021;: pubmed publisher

Zhao P, Tassew G, Lee J, Oskouian B, Muñoz D, Hodgin J, et al. Efficacy of AAV9-mediated SGPL1 gene transfer in a mouse model of S1P lyase insufficiency syndrome. JCI Insight. 2021;6: pubmed publisher

Lin C, Yang W, Lin Y, Tang X, Chen P, Ding C, et al. DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway. Oncogene. 2021;40:2018-2034 pubmed publisher

Ni X, Zhang Y, Jia L, Lu W, Zhu Q, Ren J, et al. Inhibition of Notch1-mediated inflammation by intermedin protects against abdominal aortic aneurysm via PI3K/Akt signaling pathway. Aging (Albany NY). 2021;13:5164-5184 pubmed publisher

Luo X, Xu Y, Li Y, Zhang G, Huang S, Liu X, et al. BAP1 deletion abrogates growth and metastasis of murine cutaneous melanoma. Melanoma Res. 2021;31:119-129 pubmed publisher

Jin Y, Sun X, Pei F, Zhao Z, Mao J. Wnt16 signaling promotes osteoblast differentiation of periosteal derived cells in vitro and in vivo. Peerj. 2020;8:e10374 pubmed publisher

Molinuevo R, Freije A, Contreras L, Sanz J, Gandarillas A. The DNA damage response links human squamous proliferation with differentiation. J Cell Biol. 2020;219: pubmed publisher

An M, Kim H, Moon J, Ko H, Clayton P, Lim Y. Enzyme-Treated Zizania latifolia Ethanol Extract Protects from UVA Irradiation-Induced Wrinkle Formation via Inhibition of Lysosome Exocytosis and Reactive Oxygen Species Generation. Antioxidants (Basel). 2020;9: pubmed publisher

Göbel A, Zinna V, Dell Endice S, Jaschke N, Kuhlmann J, Wimberger P, et al. Anti-tumor effects of mevalonate pathway inhibition in ovarian cancer. BMC Cancer. 2020;20:703 pubmed publisher

Romano G, Klima R, Feiguin F. TDP-43 prevents retrotransposon activation in the Drosophila motor system through regulation of Dicer-2 activity. BMC Biol. 2020;18:82 pubmed publisher

Szeiffova Bacova B, Viczenczová C, Andelova K, Sykora M, Chaudagar K, Barancik M, et al. Antiarrhythmic Effects of Melatonin and Omega-3 Are Linked with Protection of Myocardial Cx43 Topology and Suppression of Fibrosis in Catecholamine Stressed Normotensive and Hypertensive Rats. Antioxidants (Basel). 2020;9: pubmed publisher

Haider N, Dutt P, van de Kooij B, Ho J, Palomero L, Pujana M, et al. NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity. Oncogene. 2020;39:5252-5266 pubmed publisher

Nicolaou O, Sokratous K, Makowska Z, Morell M, De Groof A, Montigny P, et al. Proteomic analysis in lupus mice identifies Coronin-1A as a potential biomarker for lupus nephritis. Arthritis Res Ther. 2020;22:147 pubmed publisher

Ding C, Rose J, Sun T, Wu J, Chen P, Lin C, et al. MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis. Nat Metab. 2020;2:270-277 pubmed publisher

Whiffin N, Armean I, Kleinman A, Marshall J, Minikel E, Goodrich J, et al. The effect of LRRK2 loss-of-function variants in humans. Nat Med. 2020;26:869-877 pubmed publisher

Yang Y, Mei Q. Accumulation of AGO2 Facilitates Tumorigenesis of Human Hepatocellular Carcinoma. Biomed Res Int. 2020;2020:1631843 pubmed publisher

Ghosh A, Rao V, Wisniewski V, Zigrossi A, Floss J, Koulen P, et al. Differential Activation of Glioprotective Intracellular Signaling Pathways in Primary Optic Nerve Head Astrocytes after Treatment with Different Classes of Antioxidants. Antioxidants (Basel). 2020;9: pubmed publisher

Strah N, Romano G, Introna C, Klima R, Marzullo M, Ciapponi L, et al. TDP-43 promotes the formation of neuromuscular synapses through the regulation of Disc-large expression in Drosophila skeletal muscles. BMC Biol. 2020;18:34 pubmed publisher

Hong A, Meng Z, Plouffe S, Lin Z, Zhang M, Guan K. Critical roles of phosphoinositides and NF2 in Hippo pathway regulation. Genes Dev. 2020;34:511-525 pubmed publisher

Xia P, Chen J, Liu Y, Fletcher M, Jensen B, Cheng Z. Doxorubicin induces cardiomyocyte apoptosis and atrophy through cyclin-dependent kinase 2-mediated activation of forkhead box O1. J Biol Chem. 2020;295:4265-4276 pubmed publisher

Chen W, Cai Z, Chao E, Chen H, Longley C, Hao S, et al. Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy. elife. 2020;9: pubmed publisher

Lee D, Park S, Huh Y, Jung Kim M, Seo H, Ha T, et al. Iridoids of Valeriana fauriei contribute to alleviating hepatic steatosis in obese mice by lipophagy. Biomed Pharmacother. 2020;125:109950 pubmed publisher

Lin C, Mabe N, Lin Y, Yang W, Tang X, Hong L, et al. RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence. Cell Death Differ. 2020;27:2234-2247 pubmed publisher

Zhao L, Ke H, Xu H, Wang G, Zhang H, Zou L, et al. TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh. Nat Commun. 2020;11:341 pubmed publisher

Chen Z, Zhong H, Wei J, Lin S, Zong Z, Gong F, et al. Inhibition of Nrf2/HO-1 signaling leads to increased activation of the NLRP3 inflammasome in osteoarthritis. Arthritis Res Ther. 2019;21:300 pubmed publisher

Crochemore C, Fernandez Molina C, Montagne B, Salles A, Ricchetti M. CSB promoter downregulation via histone H3 hypoacetylation is an early determinant of replicative senescence. Nat Commun. 2019;10:5576 pubmed publisher

Carter R, Milani M, Butterworth M, Alotibi A, Harper N, Yedida G, et al. Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck. Cell Death Dis. 2019;10:912 pubmed publisher

Chung J, Kim K, An S, Lee S, Lim B, Kang S, et al. Coxsackievirus and adenovirus receptor mediates the responses of endothelial cells to fluid shear stress. Exp Mol Med. 2019;51:144 pubmed publisher

Guo R, Kim S, Choi C, Na C, Kang B, Kim Y. Inhibitory effects of ChondroT and its constituent herbs on RANKL-induced osteoclastogenesis. BMC Complement Altern Med. 2019;19:319 pubmed publisher

Carper M, Troutman S, Wagner B, Byrd K, Selitsky S, Parag Sharma K, et al. An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma. Cell Rep. 2019;29:1660-1674.e7 pubmed publisher

Semaan L, Mander N, Cher M, Chinni S. TMPRSS2-ERG fusions confer efficacy of enzalutamide in an in vivo bone tumor growth model. BMC Cancer. 2019;19:972 pubmed publisher

Kim J, Khalil A, Kim H, Kim S, Ahn M. 2-Methoxy-7-Acetonyljuglone Isolated from Reynoutria japonica Increases the Activity of Nuclear Factor Erythroid 2-Related Factor-2 through Inhibition of Ubiquitin Degradation in HeLa Cells. Antioxidants (Basel). 2019;8: pubmed publisher

Barbero G, Castro M, Villanueva M, Quezada M, Fernández N, Demorrow S, et al. An Autocrine Wnt5a Loop Promotes NF-κB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma. Cells. 2019;8: pubmed publisher

Yu X, Zhang Y, Wu B, Kurie J, Pertsemlidis A. The miR-195 Axis Regulates Chemoresistance through TUBB and Lung Cancer Progression through BIRC5. Mol Ther Oncolytics. 2019;14:288-298 pubmed publisher

Gary C, Lam S, Herard A, Koch J, Petit F, Gipchtein P, et al. Encephalopathy induced by Alzheimer brain inoculation in a non-human primate. Acta Neuropathol Commun. 2019;7:126 pubmed publisher

Corkins M, Krneta Stankic V, Kloc M, McCrea P, Gladden A, Miller R. Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis. PLoS ONE. 2019;14:e0221698 pubmed publisher

Bordignon P, Bottoni G, Xu X, Popescu A, Truan Z, Guenova E, et al. Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant. Cell Rep. 2019;28:2358-2372.e6 pubmed publisher

Parvin S, Ramírez Labrada A, Aumann S, Lu X, Weich N, Santiago G, et al. LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL. Cancer Cell. 2019;36:237-249.e6 pubmed publisher

Pacini V, Petit F, Querat B, Laverrière J, Cohen Tannoudji J, L hôte D. Identification of a pituitary ERα-activated enhancer triggering the expression of Nr5a1, the earliest gonadotrope lineage-specific transcription factor. Epigenetics Chromatin. 2019;12:48 pubmed publisher

Deng L, Ren R, Liu Z, Song M, Li J, Wu Z, et al. Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis. Nat Commun. 2019;10:3329 pubmed publisher

Ding K, Ji J, Zhang X, Huang B, Chen A, Zhang D, et al. RNA splicing factor USP39 promotes glioma progression by inducing TAZ mRNA maturation. Oncogene. 2019;38:6414-6428 pubmed publisher

Park H, Yu D, Sung M, Oh E, Kim M, Song J, et al. Molecular changes in solitary fibrous tumor progression. J Mol Med (Berl). 2019;97:1413-1425 pubmed publisher

Zhu C, Li L, Zhang Z, Bi M, Wang H, Su W, et al. A Non-canonical Role of YAP/TEAD Is Required for Activation of Estrogen-Regulated Enhancers in Breast Cancer. Mol Cell. 2019;75:791-806.e8 pubmed publisher

Reimer M, Pulakanti K, Shi L, Abel A, Liang M, Malarkannan S, et al. Deletion of Tet proteins results in quantitative disparities during ESC differentiation partially attributable to alterations in gene expression. BMC Dev Biol. 2019;19:16 pubmed publisher

Kaur S, Nag A, Gangenahalli G, Sharma K. Peroxisome Proliferator Activated Receptor Gamma Sensitizes Non-small Cell Lung Carcinoma to Gamma Irradiation Induced Apoptosis. Front Genet. 2019;10:554 pubmed publisher

Huang H, Kong W, Jean M, Fiches G, Zhou D, Hayashi T, et al. A CRISPR/Cas9 screen identifies the histone demethylase MINA53 as a novel HIV-1 latency-promoting gene (LPG). Nucleic Acids Res. 2019;: pubmed publisher

Torrini C, Cubero R, Dirkx E, Braga L, Ali H, Prosdocimo G, et al. Common Regulatory Pathways Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation. Cell Rep. 2019;27:2759-2771.e5 pubmed publisher

Rollins M, Jha S, Bartom E, Walsh D. RACK1 evolved species-specific multifunctionality in translational control through sequence plasticity within a loop domain. J Cell Sci. 2019;132: pubmed publisher

Zhang N, Heruth D, Wu W, Zhang L, Nsumu M, Shortt K, et al. Functional characterization of SLC26A3 c.392C>G (p.P131R) mutation in intestinal barrier function using CRISPR/CAS9-created cell models. Cell Biosci. 2019;9:40 pubmed publisher

Cho E, Jung W, Joo H, Park E, Kim M, Kim S, et al. Cluh plays a pivotal role during adipogenesis by regulating the activity of mitochondria. Sci Rep. 2019;9:6820 pubmed publisher

Lee Y, Lahens N, Zhang S, Bedont J, FIELD J, Sehgal A. G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment. PLoS Biol. 2019;17:e3000228 pubmed publisher

Lewis R, Li Y, Hoffman L, Hashizume R, Gravohac G, Rice G, et al. Global Reduction of H3K4me3 Improves Chemotherapeutic Efficacy for Pediatric Ependymomas. Neoplasia. 2019;21:505-515 pubmed publisher

Higuchi T, Takagi K, Tochimoto A, Ichimura Y, Norose T, Katsumata Y, et al. Antifibrotic effects of 2-carba cyclic phosphatidic acid (2ccPA) in systemic sclerosis: contribution to the novel treatment. Arthritis Res Ther. 2019;21:103 pubmed publisher

Chen L, Toke N, Luo S, Vasoya R, Fullem R, Parthasarathy A, et al. A reinforcing HNF4-SMAD4 feed-forward module stabilizes enterocyte identity. Nat Genet. 2019;51:777-785 pubmed publisher

Sakaguchi M, Cai W, Wang C, Cederquist C, Damasio M, Homan E, et al. FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism. Nat Commun. 2019;10:1582 pubmed publisher

Poggio M, Hu T, Pai C, Chu B, BELAIR C, Chang A, et al. Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory. Cell. 2019;177:414-427.e13 pubmed publisher

Scavello F, Zeni F, Tedesco C, Mensà E, Veglia F, Procopio A, et al. Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging. Aging (Albany NY). 2019;11:1648-1663 pubmed publisher

Li H, Petersen S, García Mariscal A, Brakebusch C. Negative Regulation of p53-Induced Senescence by N-WASP Is Crucial for DMBA/TPA-Induced Skin Tumor Formation. Cancer Res. 2019;79:2167-2181 pubmed publisher

Arceci A, Bonacci T, Wang X, Stewart K, Damrauer J, Hoadley K, et al. FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer. Cell Rep. 2019;26:3076-3086.e6 pubmed publisher

Pabon N, Zhang Q, Cruz J, Schipper D, Camacho C, Lee R. A network-centric approach to drugging TNF-induced NF-κB signaling. Nat Commun. 2019;10:860 pubmed publisher

Chaurasia M, Gupta S, Das A, Dwarakanath B, Simonsen A, Sharma K. Radiation induces EIF2AK3/PERK and ERN1/IRE1 mediated pro-survival autophagy. Autophagy. 2019;15:1391-1406 pubmed publisher

Chang H, Cho S, Lee J, Lee E, Seo J, Lee H, et al. Hypomorphic Mutations in TONSL Cause SPONASTRIME Dysplasia. Am J Hum Genet. 2019;104:439-453 pubmed publisher

Li Y, Jiang X, Zhang Y, Gao Z, Liu Y, Hu J, et al. Nuclear accumulation of UBC9 contributes to SUMOylation of lamin A/C and nucleophagy in response to DNA damage. J Exp Clin Cancer Res. 2019;38:67 pubmed publisher

Shortt K, Heruth D, Zhang N, Wu W, Singh S, Li D, et al. Identification of Novel Regulatory Genes in APAP Induced Hepatocyte Toxicity by a Genome-Wide CRISPR-Cas9 Screen. Sci Rep. 2019;9:1396 pubmed publisher

Mengwasser K, Adeyemi R, Leng Y, Choi M, Clairmont C, D Andrea A, et al. Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets. Mol Cell. 2019;73:885-899.e6 pubmed publisher

Alameda J, Ramirez A, Garcia Fernandez R, Navarro M, Page A, Segovia J, et al. Premature aging and cancer development in transgenic mice lacking functional CYLD. Aging (Albany NY). 2019;11:127-159 pubmed publisher

Narayana Y, Gadgil C, Mote R, Rajan R, Subramanyam D. Clathrin-Mediated Endocytosis Regulates a Balance between Opposing Signals to Maintain the Pluripotent State of Embryonic Stem Cells. Stem Cell Reports. 2019;12:152-164 pubmed publisher

Masola V, Bellin G, Vischini G, Dall Olmo L, Granata S, Gambaro G, et al. Inhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury. Oncotarget. 2018;9:36185-36201 pubmed publisher

Hatzi K, Geng H, Doane A, Meydan C, LaRiviere R, Cárdenas M, et al. Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis. Nat Immunol. 2019;20:86-96 pubmed publisher

Chen L, Pastorino F, Berry P, Bonner J, Kirk C, Wood K, et al. Preclinical evaluation of the first intravenous small molecule MDM2 antagonist alone and in combination with temozolomide in neuroblastoma. Int J Cancer. 2019;144:3146-3159 pubmed publisher

Kim J, Afshari A, Sengupta R, Sebastiano V, Gupta A, Kim Y, et al. Replication study: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. elife. 2018;7: pubmed publisher

Bressy C, Droby G, Maldonado B, Steuerwald N, Grdzelishvili V. Cell Cycle Arrest in G2/M Phase Enhances Replication of Interferon-Sensitive Cytoplasmic RNA Viruses via Inhibition of Antiviral Gene Expression. J Virol. 2019;93: pubmed publisher

Shi M, Chen B, Mahajan D, Boh B, Zhou Y, Dutta B, et al. Amino acids stimulate the endosome-to-Golgi trafficking through Ragulator and small GTPase Arl5. Nat Commun. 2018;9:4987 pubmed publisher

Matkovic R, Bernard E, Fontanel S, Eldin P, Chazal N, Hassan Hersi D, et al. The Host DHX9 DExH-Box Helicase Is Recruited to Chikungunya Virus Replication Complexes for Optimal Genomic RNA Translation. J Virol. 2019;93: pubmed publisher

Ratcliffe C, Siddiqui N, Coelho P, Laterreur N, Cookey T, Sonenberg N, et al. HGF-induced migration depends on the PI(3,4,5)P3-binding microexon-spliced variant of the Arf6 exchange factor cytohesin-1. J Cell Biol. 2019;218:285-298 pubmed publisher

Cheng C, Qi Y, Wang Y, Chi K, Chung Y, Ouyang C, et al. Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction. Commun Biol. 2018;1:178 pubmed publisher

Xia P, Liu Y, Chen J, Coates S, Liu D, Cheng Z. Inhibition of cyclin-dependent kinase 2 protects against doxorubicin-induced cardiomyocyte apoptosis and cardiomyopathy. J Biol Chem. 2018;293:19672-19685 pubmed publisher

Kim Y, Park W, Ahn S, Sung D, Chang Y. Intratracheal transplantation of mesenchymal stem cells attenuates hyperoxia-induced lung injury by down-regulating, but not direct inhibiting formyl peptide receptor 1 in the newborn mice. PLoS ONE. 2018;13:e0206311 pubmed publisher

Simhadri S, Vincelli G, Huo Y, Misenko S, Foo T, Ahlskog J, et al. PALB2 connects BRCA1 and BRCA2 in the G2/M checkpoint response. Oncogene. 2019;38:1585-1596 pubmed publisher

Kabacik S, Horvath S, Cohen H, Raj K. Epigenetic ageing is distinct from senescence-mediated ageing and is not prevented by telomerase expression. Aging (Albany NY). 2018;10:2800-2815 pubmed publisher

Muramatsu M, Akakura S, Gao L, Peresie J, Balderman B, Gelman I. SSeCKS/Akap12 suppresses metastatic melanoma lung colonization by attenuating Src-mediated pre-metastatic niche crosstalk. Oncotarget. 2018;9:33515-33527 pubmed publisher

Li W, Yue F, Dai Y, Shi B, Xu G, Jiang X, et al. Suppressor of hepatocellular carcinoma RASSF1A activates autophagy initiation and maturation. Cell Death Differ. 2018;: pubmed publisher

Inoue K, Deng Z, Chen Y, Giannopoulou E, Xu R, Gong S, et al. Bone protection by inhibition of microRNA-182. Nat Commun. 2018;9:4108 pubmed publisher

Dong P, Zhang X, Zhao J, Li D, Li L, Yang B. Anti-microRNA-132 causes sevoflurane‑induced neuronal apoptosis via the PI3K/AKT/FOXO3a pathway. Int J Mol Med. 2018;42:3238-3246 pubmed publisher

Pan H, Palekar R, Hou K, Bacon J, Yan H, Springer L, et al. Anti-JNK2 peptide-siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice. Int J Nanomedicine. 2018;13:5187-5205 pubmed publisher

Ma Z, Sun H, Lv J, Guo L, Yang Q. Expression and clinical significance of the NEK7-NLRP3 inflammasome signaling pathway in patients with systemic lupus erythematosus. J Inflamm (Lond). 2018;15:16 pubmed publisher

Cai W, Wu S, Pan Z, Xiao J, Li F, Cao J, et al. Disrupting interaction of PSD-95 with nNOS attenuates hemorrhage-induced thalamic pain. Neuropharmacology. 2018;141:238-248 pubmed publisher

Abbasi F, Miyata H, Shimada K, Morohoshi A, Nozawa K, Matsumura T, et al. RSPH6A is required for sperm flagellum formation and male fertility in mice. J Cell Sci. 2018;131: pubmed publisher

Zhang L, Li X, Chao Y, He R, Liu J, Yuan Y, et al. KLF4, a miR-32-5p targeted gene, promotes cisplatin-induced apoptosis by upregulating BIK expression in prostate cancer. Cell Commun Signal. 2018;16:53 pubmed publisher

Mackey L, Annab L, Yang J, Rao B, Kissling G, Schurman S, et al. Epigenetic Enzymes, Age, and Ancestry Regulate the Efficiency of Human iPSC Reprogramming. Stem Cells. 2018;36:1697-1708 pubmed publisher

Lee M, Han H, Han S, Kim I, Chae S, Lee C, et al. Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation. Nat Commun. 2018;9:3404 pubmed publisher

Lei K, Sun R, Chen L, Diplas B, Moure C, Wang W, et al. Mutant allele quantification reveals a genetic basis for TP53 mutation-driven castration resistance in prostate cancer cells. Sci Rep. 2018;8:12507 pubmed publisher

Kwapis J, Alaghband Y, Kramar E, Lopez A, Vogel Ciernia A, White A, et al. Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory. Nat Commun. 2018;9:3323 pubmed publisher

Kong X, Martinez Barricarte R, Kennedy J, Mele F, Lazarov T, Deenick E, et al. Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency. Nat Immunol. 2018;19:973-985 pubmed publisher

Richardson B, Jain A, Potteti H, Lazzara P, David B, Tamatam C, et al. Replacement of a Naphthalene Scaffold in Kelch-like ECH-Associated Protein 1 (KEAP1)/Nuclear Factor (Erythroid-derived 2)-like 2 (NRF2) Inhibitors. J Med Chem. 2018;61:8029-8047 pubmed publisher

Lamothe S, Hogan Cann A, Li W, Guo J, Yang T, Tschirhart J, et al. The N terminus and transmembrane segment S1 of Kv1.5 can coassemble with the rest of the channel independently of the S1-S2 linkage. J Biol Chem. 2018;293:15347-15358 pubmed publisher

Latremoliere A, Cheng L, DeLisle M, Wu C, Chew S, Hutchinson E, et al. Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration. Cell Rep. 2018;24:1865-1879.e9 pubmed publisher

Qian K, Feng L, Sun Y, Xiong B, Ding Y, Han P, et al. Overexpression of Salusin-α Inhibits Vascular Intimal Hyperplasia in an Atherosclerotic Rabbit Model. Biomed Res Int. 2018;2018:8973986 pubmed publisher

Zhang D, Lin J, Chao Y, Zhang L, Jin L, Li N, et al. Regulation of the adaptation to ER stress by KLF4 facilitates melanoma cell metastasis via upregulating NUCB2 expression. J Exp Clin Cancer Res. 2018;37:176 pubmed publisher

Freimer J, Hu T, Blelloch R. Decoupling the impact of microRNAs on translational repression versus RNA degradation in embryonic stem cells. elife. 2018;7: pubmed publisher

Kühnl A, Musiol A, Heitzig N, Johnson D, Ehrhardt C, Grewal T, et al. Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus. MBio. 2018;9: pubmed publisher

Sizemore G, Balakrishnan S, Thies K, Hammer A, Sizemore S, TRIMBOLI A, et al. Stromal PTEN determines mammary epithelial response to radiotherapy. Nat Commun. 2018;9:2783 pubmed publisher

Zhao X, Yu H, Yang Y, Wu W, Chen T, Jia K, et al. Polydatin prevents fructose-induced liver inflammation and lipid deposition through increasing miR-200a to regulate Keap1/Nrf2 pathway. Redox Biol. 2018;18:124-137 pubmed publisher

Sabbir M, Calcutt N, Fernyhough P. Muscarinic Acetylcholine Type 1 Receptor Activity Constrains Neurite Outgrowth by Inhibiting Microtubule Polymerization and Mitochondrial Trafficking in Adult Sensory Neurons. Front Neurosci. 2018;12:402 pubmed publisher

Langlois A, Marinach C, Manzoni G, Silvie O. Plasmodium sporozoites can invade hepatocytic cells independently of the Ephrin receptor A2. PLoS ONE. 2018;13:e0200032 pubmed publisher

Bonacci T, Suzuki A, Grant G, Stanley N, Cook J, Brown N, et al. Cezanne/OTUD7B is a cell cycle-regulated deubiquitinase that antagonizes the degradation of APC/C substrates. EMBO J. 2018;37: pubmed publisher

Okano Uchida T, Kent L, Ouseph M, McCarty B, Frank J, Kladney R, et al. Endoreduplication of the mouse genome in the absence of ORC1. Genes Dev. 2018;32:978-990 pubmed publisher

Barutcu S, Girnius N, Vernia S, Davis R. Role of the MAPK/cJun NH2-terminal kinase signaling pathway in starvation-induced autophagy. Autophagy. 2018;14:1586-1595 pubmed publisher

Stein C, Jadiya P, Zhang X, McLendon J, Abouassaly G, Witmer N, et al. Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency. Cell Rep. 2018;23:3710-3720.e8 pubmed publisher

Jayson C, Arlt H, Fischer A, Lai Z, Farese R, Walther T. Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells. Mol Biol Cell. 2018;29:2045-2054 pubmed publisher

Kaneko S, Li X. X chromosome protects against bladder cancer in females via a KDM6A-dependent epigenetic mechanism. Sci Adv. 2018;4:eaar5598 pubmed publisher

Tiwarekar V, Wohlfahrt J, Fehrholz M, Scholz C, Kneitz S, Schneider Schaulies J. APOBEC3G-Regulated Host Factors Interfere with Measles Virus Replication: Role of REDD1 and Mammalian TORC1 Inhibition. J Virol. 2018;92: pubmed publisher

Zonneville J, Safina A, Truskinovsky A, Arteaga C, Bakin A. TGF-β signaling promotes tumor vasculature by enhancing the pericyte-endothelium association. BMC Cancer. 2018;18:670 pubmed publisher

Wang Y, Sun H, Kumar S, Puerta M, Jo H, Rezvan A. ZBTB46 is a shear-sensitive transcription factor inhibiting endothelial cell proliferation via gene expression regulation of cell cycle proteins. Lab Invest. 2019;99:305-318 pubmed publisher

Brennan L, McGreal Estrada R, Logan C, Cvekl A, Menko A, Kantorow M. BNIP3L/NIX is required for elimination of mitochondria, endoplasmic reticulum and Golgi apparatus during eye lens organelle-free zone formation. Exp Eye Res. 2018;174:173-184 pubmed publisher

Back M, Ha H, Fu Z, Choi J, Piao Y, Won J, et al. Activation of neutral sphingomyelinase 2 by starvation induces cell-protective autophagy via an increase in Golgi-localized ceramide. Cell Death Dis. 2018;9:670 pubmed publisher

Brown Z, Fu Q, Ma C, Kruhlak M, Zhang H, Luo J, et al. Carnitine palmitoyltransferase gene upregulation by linoleic acid induces CD4+ T cell apoptosis promoting HCC development. Cell Death Dis. 2018;9:620 pubmed publisher

Reddy V, Chinta K, Saini V, Glasgow J, Hull T, Traylor A, et al. Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection. Front Immunol. 2018;9:860 pubmed publisher

Liu H, Lorenzini P, Zhang F, Xu S, Wong M, Zheng J, et al. Alternative splicing analysis in human monocytes and macrophages reveals MBNL1 as major regulator. Nucleic Acids Res. 2018;46:6069-6086 pubmed publisher

Ménard M, Costechareyre C, Ichim G, Blachier J, Neves D, Jarrosson Wuilleme L, et al. Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth. PLoS Biol. 2018;16:e2002912 pubmed publisher

Wang Q, Gao G, Zhang T, Yao K, Chen H, Park M, et al. TRAF1 Is Critical for Regulating the BRAF/MEK/ERK Pathway in Non-Small Cell Lung Carcinogenesis. Cancer Res. 2018;78:3982-3994 pubmed publisher

Walker J, Bleaken B, Romisher A, Alnwibit A, Menko A. In wound repair vimentin mediates the transition of mesenchymal leader cells to a myofibroblast phenotype. Mol Biol Cell. 2018;29:1555-1570 pubmed publisher

Aboudehen K, Farahani S, Kanchwala M, Chan S, Avdulov S, Mickelson A, et al. Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018;293:9388-9398 pubmed publisher

Stroobants S, Wolf H, Callaerts Vegh Z, Dierks T, Lübke T, D Hooge R. Sensorimotor and Neurocognitive Dysfunctions Parallel Early Telencephalic Neuropathology in Fucosidosis Mice. Front Behav Neurosci. 2018;12:69 pubmed publisher

Peng X, Xu X, Wang Y, Hawke D, Yu S, Han L, et al. A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer. Cancer Cell. 2018;33:817-828.e7 pubmed publisher

Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed publisher

Zhou L, Wang Y, Zhou M, Zhang Y, Wang P, Li X, et al. HOXA9 inhibits HIF-1α-mediated glycolysis through interacting with CRIP2 to repress cutaneous squamous cell carcinoma development. Nat Commun. 2018;9:1480 pubmed publisher

Guissart C, Latypova X, Rollier P, Khan T, Stamberger H, McWalter K, et al. Dual Molecular Effects of Dominant RORA Mutations Cause Two Variants of Syndromic Intellectual Disability with Either Autism or Cerebellar Ataxia. Am J Hum Genet. 2018;102:744-759 pubmed publisher

Yu X, Zhang Y, Ma X, Pertsemlidis A. miR-195 potentiates the efficacy of microtubule-targeting agents in non-small cell lung cancer. Cancer Lett. 2018;427:85-93 pubmed publisher

Wang Z, Yang B, Zhang M, Guo W, Wu Z, Wang Y, et al. lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer. Cancer Cell. 2018;33:706-720.e9 pubmed publisher

Pentimalli F, Forte I, Esposito L, Indovina P, Iannuzzi C, Alfano L, et al. RBL2/p130 is a direct AKT target and is required to induce apoptosis upon AKT inhibition in lung cancer and mesothelioma cell lines. Oncogene. 2018;37:3657-3671 pubmed publisher

Liu N, Hargreaves V, Zhu Q, Kurland J, Hong J, Kim W, et al. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch. Cell. 2018;173:430-442.e17 pubmed publisher

Pan L, Wu Y, Wang R, Chen J, Chen J, Zhang Y, et al. (-)-Epigallocatechin-3-Gallate Ameliorates Atherosclerosis and Modulates Hepatic Lipid Metabolic Gene Expression in Apolipoprotein E Knockout Mice: Involvement of TTC39B. Front Pharmacol. 2018;9:195 pubmed publisher

Kraakman M, Liu Q, Postigo Fernandez J, Ji R, Kon N, Larrea D, et al. PPAR? deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects. J Clin Invest. 2018;128:2600-2612 pubmed publisher

Kinyua A, Doan K, Yang D, Huynh M, Choi Y, Shin D, et al. Insulin Regulates Adrenal Steroidogenesis by Stabilizing SF-1 Activity. Sci Rep. 2018;8:5025 pubmed publisher

Russell J, Ko S, Saggi H, Singh S, Poddar M, Shin D, et al. Bromodomain and Extraterminal (BET) Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration. Am J Pathol. 2018;188:1389-1405 pubmed publisher

Lin C, Kitagawa M, Tang X, Hou M, Wu J, Qu D, et al. CoA synthase regulates mitotic fidelity via CBP-mediated acetylation. Nat Commun. 2018;9:1039 pubmed publisher

Danyukova T, Ariunbat K, Thelen M, Brocke Ahmadinejad N, Mole S, Storch S. Loss of CLN7 results in depletion of soluble lysosomal proteins and impaired mTOR reactivation. Hum Mol Genet. 2018;27:1711-1722 pubmed publisher

Wang Q, Yu J, Kadungure T, Beyene J, Zhang H, Lu Q. ARMMs as a versatile platform for intracellular delivery of macromolecules. Nat Commun. 2018;9:960 pubmed publisher

Sarikhani M, Mishra S, Maity S, Kotyada C, Wolfgeher D, Gupta M, et al. SIRT2 deacetylase regulates the activity of GSK3 isoforms independent of inhibitory phosphorylation. elife. 2018;7: pubmed publisher

Zhao Y, Mao M, Zhang W, Wang J, Li H, Yang Y, et al. Expanding RNA binding specificity and affinity of engineered PUF domains. Nucleic Acids Res. 2018;46:4771-4782 pubmed publisher

Delorme Axford E, Abernathy E, Lennemann N, Bernard A, Ariosa A, Coyne C, et al. The exoribonuclease Xrn1 is a post-transcriptional negative regulator of autophagy. Autophagy. 2018;14:898-912 pubmed publisher

Lu D, Liao H, Chen C, Tu H, Liou H, Gau S, et al. Impairment of social behaviors in Arhgef10 knockout mice. Mol Autism. 2018;9:11 pubmed publisher

Wu Q, Xiao Y, Duan M, Yuan Y, Jiang X, Yang Z, et al. Aucubin protects against pressure overload-induced cardiac remodelling via the β3 -adrenoceptor-neuronal NOS cascades. Br J Pharmacol. 2018;175:1548-1566 pubmed publisher

Ibar C, Kirichenko E, Keepers B, Enners E, Fleisch K, Irvine K. Tension-dependent regulation of mammalian Hippo signaling through LIMD1. J Cell Sci. 2018;131: pubmed publisher

Zhang F, Brenner M, Yang W, Wang P. A cold-inducible RNA-binding protein (CIRP)-derived peptide attenuates inflammation and organ injury in septic mice. Sci Rep. 2018;8:3052 pubmed publisher

Wang S, Hu B, Ding Z, Dang Y, Wu J, Li D, et al. ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells. Cell Discov. 2018;4:2 pubmed publisher

Legler K, Rosprim R, Karius T, Eylmann K, Rossberg M, Wirtz R, et al. Reduced mannosidase MAN1A1 expression leads to aberrant N-glycosylation and impaired survival in breast cancer. Br J Cancer. 2018;118:847-856 pubmed publisher

Jiang M, Xu C, Guo Y, Luo Q, Li L, Liu H, et al. ?-arrestin 2 attenuates lipopolysaccharide-induced liver injury via inhibition of TLR4/NF-?B signaling pathway-mediated inflammation in mice. World J Gastroenterol. 2018;24:216-225 pubmed publisher

Liang H, Xiao J, Zhou Z, Wu J, Ge F, Li Z, et al. Hypoxia induces miR-153 through the IRE1α-XBP1 pathway to fine tune the HIF1α/VEGFA axis in breast cancer angiogenesis. Oncogene. 2018;37:1961-1975 pubmed publisher

Uchino Y, Woodward A, Mauris J, Peterson K, Verma P, Nilsson U, et al. Galectin-3 is an amplifier of the interleukin-1β-mediated inflammatory response in corneal keratinocytes. Immunology. 2018;154:490-499 pubmed publisher

Leo D, Sukhanov I, Zoratto F, Illiano P, Caffino L, Sanna F, et al. Pronounced Hyperactivity, Cognitive Dysfunctions, and BDNF Dysregulation in Dopamine Transporter Knock-out Rats. J Neurosci. 2018;38:1959-1972 pubmed publisher

Liang Y, Liu L, Jin Z, Liang X, Fu Y, Gu X, et al. The high concentration of progesterone is harmful for endometrial receptivity and decidualization. Sci Rep. 2018;8:712 pubmed publisher

Li Y, Shang P, Shyu D, Carrillo C, Naraghi Arani P, Jaing C, et al. Nonstructural proteins nsp2TF and nsp2N of porcine reproductive and respiratory syndrome virus (PRRSV) play important roles in suppressing host innate immune responses. Virology. 2018;517:164-176 pubmed publisher

Choi J, Kim K, Koh E, Lee B. Gelidium elegans Extract Ameliorates Type 2 Diabetes via Regulation of MAPK and PI3K/Akt Signaling. Nutrients. 2018;10: pubmed publisher

Ding D, Bergmaier P, Sachs P, Klangwart M, Rückert T, Bartels N, et al. The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 mediates its association with KRAB-associated protein 1 (KAP1) and KAP1 target genes. J Biol Chem. 2018;293:2711-2724 pubmed publisher

Namasu C, Katzerke C, Bräuer Hartmann D, Wurm A, Gerloff D, Hartmann J, et al. ABR, a novel inducer of transcription factor C/EBP?, contributes to myeloid differentiation and is a favorable prognostic factor in acute myeloid leukemia. Oncotarget. 2017;8:103626-103639 pubmed publisher

Su Y, Chen R, Wang H, Song H, Zhang Q, Chen L, et al. Novel Targeting of Transcription and Metabolism in Glioblastoma. Clin Cancer Res. 2018;24:1124-1137 pubmed publisher

Chen G, Du C, Shen Z, Peng L, Xie H, Zang R, et al. MicroRNA-939 inhibits cell proliferation via targeting LRSAM1 in Hirschsprung's disease. Aging (Albany NY). 2017;9:2471-2479 pubmed publisher

Cho M, Lee J, Shin M, Kim H, Choi Y, Rho S, et al. TSC-22 inhibits CSF-1R function and induces apoptosis in cervical cancer. Oncotarget. 2017;8:97990-98003 pubmed publisher

Park S, Lee H, Seo Y, Son C, Bae H, Park J. Dentin sialophosphoprotein expression in enamel is regulated by Copine-7, a preameloblast-derived factor. Arch Oral Biol. 2018;86:131-137 pubmed publisher

Abdul A, De Silva B, Gary R. The GSK3 kinase inhibitor lithium produces unexpected hyperphosphorylation of β-catenin, a GSK3 substrate, in human glioblastoma cells. Biol Open. 2018;7: pubmed publisher

McNair C, Xu K, Mandigo A, Benelli M, Leiby B, Rodrigues D, et al. Differential impact of RB status on E2F1 reprogramming in human cancer. J Clin Invest. 2018;128:341-358 pubmed publisher

Kullar P, Gómez Durán A, Gammage P, Garone C, Minczuk M, Golder Z, et al. Heterozygous SSBP1 start loss mutation co-segregates with hearing loss and the m.1555A>G mtDNA variant in a large multigenerational family. Brain. 2018;141:55-62 pubmed publisher

Wu S, Lu Q, Wang N, Zhang J, Liu Q, Gao M, et al. Cyclic stretch induced-retinal pigment epithelial cell apoptosis and cytokine changes. BMC Ophthalmol. 2017;17:208 pubmed publisher

Yu L, Liu S, Zhao Z, Xia L, Zhang H, Lou J, et al. Extracorporeal Shock Wave Rebuilt Subchondral Bone In Vivo and Activated Wnt5a/Ca2+ Signaling In Vitro. Biomed Res Int. 2017;2017:1404650 pubmed publisher

Fung K, Wang C, Nyegaard S, Heit B, Fairn G, Lee W. SR-BI Mediated Transcytosis of HDL in Brain Microvascular Endothelial Cells Is Independent of Caveolin, Clathrin, and PDZK1. Front Physiol. 2017;8:841 pubmed publisher

Deng J, Orsini C, Shimp K, Setlow B. MeCP2 Expression in a Rat Model of Risky Decision Making. Neuroscience. 2018;369:212-221 pubmed publisher

Liu Z, Zhang C, Skamagki M, Khodadadi Jamayran A, Zhang W, Kong D, et al. Elevated p53 Activities Restrict Differentiation Potential of MicroRNA-Deficient Pluripotent Stem Cells. Stem Cell Reports. 2017;9:1604-1617 pubmed publisher

Wu X, Shi T, He Y, Wang F, Sang R, Ding J, et al. Methylation of transcription factor YY2 regulates its transcriptional activity and cell proliferation. Cell Discov. 2017;3:17035 pubmed publisher

Kang H, Kumar D, Liao G, Lichti Kaiser K, Gerrish K, Liao X, et al. GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation. J Clin Invest. 2017;127:4326-4337 pubmed publisher

Xue X, Bredell B, Anderson E, Martin A, Mays C, Nagao Kitamoto H, et al. Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer. Proc Natl Acad Sci U S A. 2017;114:E9608-E9617 pubmed publisher

Muramatsu M, Gao L, Peresie J, Balderman B, Akakura S, Gelman I. SSeCKS/AKAP12 scaffolding functions suppress B16F10-induced peritoneal metastasis by attenuating CXCL9/10 secretion by resident fibroblasts. Oncotarget. 2017;8:70281-70298 pubmed publisher

Koon H, Wang J, Mussatto C, Ortiz C, Lee E, Tran D, et al. Fidaxomicin and OP-1118 Inhibit Clostridium difficile Toxin A- and B-Mediated Inflammatory Responses via Inhibition of NF-κB Activity. Antimicrob Agents Chemother. 2018;62: pubmed publisher

Yue J, Lai F, Beckedorff F, Zhang A, Pastori C, Shiekhattar R. Integrator orchestrates RAS/ERK1/2 signaling transcriptional programs. Genes Dev. 2017;31:1809-1820 pubmed publisher

Lavallée Adam M, Cloutier P, Coulombe B, Blanchette M. Functional 5' UTR motif discovery with LESMoN: Local Enrichment of Sequence Motifs in biological Networks. Nucleic Acids Res. 2017;45:10415-10427 pubmed publisher

Masoodi K, Eisermann K, Yang Z, Dar J, Pascal L, Nguyen M, et al. Inhibition of Androgen Receptor Function and Level in Castration-Resistant Prostate Cancer Cells by 2-[(isoxazol-4-ylmethyl)thio]-1-(4-phenylpiperazin-1-yl)ethanone. Endocrinology. 2017;158:3152-3161 pubmed publisher

Softic S, Gupta M, Wang G, Fujisaka S, O Neill B, Rao T, et al. Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. J Clin Invest. 2017;127:4059-4074 pubmed publisher

Cao H, Zhang S, Shan S, Sun C, Li Y, Yu S, et al. Ligand-dependent corepressor (LCoR) represses the transcription factor C/EBPβ during early adipocyte differentiation. J Biol Chem. 2017;292:18973-18987 pubmed publisher

Pham T, He J, Kakazu A, Jun B, Bazan N, Bazan H. Defining a mechanistic link between pigment epithelium-derived factor, docosahexaenoic acid, and corneal nerve regeneration. J Biol Chem. 2017;292:18486-18499 pubmed publisher

Onodera Y, Teramura T, Takehara T, Obora K, Mori T, Fukuda K. miR-155 induces ROS generation through downregulation of antioxidation-related genes in mesenchymal stem cells. Aging Cell. 2017;16:1369-1380 pubmed publisher

George J, Jolly M, Xu S, Somarelli J, Levine H. Survival Outcomes in Cancer Patients Predicted by a Partial EMT Gene Expression Scoring Metric. Cancer Res. 2017;77:6415-6428 pubmed publisher

Waraky A, Lin Y, Warsito D, Haglund F, Aleem E, Larsson O. Nuclear insulin-like growth factor 1 receptor phosphorylates proliferating cell nuclear antigen and rescues stalled replication forks after DNA damage. J Biol Chem. 2017;292:18227-18239 pubmed publisher

Skarra D, Hernandez Carretero A, Rivera A, Anvar A, Thackray V. Hyperandrogenemia Induced by Letrozole Treatment of Pubertal Female Mice Results in Hyperinsulinemia Prior to Weight Gain and Insulin Resistance. Endocrinology. 2017;158:2988-3003 pubmed publisher

Wood M, Ishiyama N, Singaram I, Chung C, Flozak A, Yemelyanov A, et al. α-Catenin homodimers are recruited to phosphoinositide-activated membranes to promote adhesion. J Cell Biol. 2017;216:3767-3783 pubmed publisher

Pascal L, Masoodi K, Liu J, Qiu X, Song Q, Wang Y, et al. Conditional deletion of ELL2 induces murine prostate intraepithelial neoplasia. J Endocrinol. 2017;235:123-136 pubmed publisher

Li X, Wang C, Zhang G, Liang M, Zhang B. AKAP2 is upregulated in ovarian cancer, and promotes growth and migration of cancer cells. Mol Med Rep. 2017;16:5151-5156 pubmed publisher

Feng Y, Lund J, Li Y, Knabenes I, Bakke S, Kase E, et al. Loss of perilipin 2 in cultured myotubes enhances lipolysis and redirects the metabolic energy balance from glucose oxidation towards fatty acid oxidation. J Lipid Res. 2017;58:2147-2161 pubmed publisher

Zaytouni T, Tsai P, Hitchcock D, DuBois C, Freinkman E, Lin L, et al. Critical role for arginase 2 in obesity-associated pancreatic cancer. Nat Commun. 2017;8:242 pubmed publisher

Oh D, Jung K, Song J, Kim S, Shin S, Kwon Y, et al. Precision medicine approaches to lung adenocarcinoma with concomitant MET and HER2 amplification. BMC Cancer. 2017;17:535 pubmed publisher

Tong X, Zhang D, Charney N, Jin E, VanDommelen K, Stamper K, et al. DDB1-Mediated CRY1 Degradation Promotes FOXO1-Driven Gluconeogenesis in Liver. Diabetes. 2017;66:2571-2582 pubmed publisher

Delaney M, Malikov V, Chai Q, Zhao G, Naghavi M. Distinct functions of diaphanous-related formins regulate HIV-1 uncoating and transport. Proc Natl Acad Sci U S A. 2017;114:E6932-E6941 pubmed publisher

Norante R, Massimino M, Lorenzon P, De Mario A, Peggion C, Vicario M, et al. Generation and validation of novel adeno-associated viral vectors for the analysis of Ca2+ homeostasis in motor neurons. Sci Rep. 2017;7:6521 pubmed publisher

Sui Z, Gokhin D, Nowak R, Guo X, An X, Fowler V. Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells. Mol Biol Cell. 2017;28:2531-2542 pubmed publisher

Li L, Zviti R, Ha C, Wang Z, Hill J, Lin F. Forkhead box O3 (FoxO3) regulates kidney tubular autophagy following urinary tract obstruction. J Biol Chem. 2017;292:13774-13783 pubmed publisher

Kroh H, Chandrasekaran R, Rosenthal K, Woods R, Jin X, Ohi M, et al. Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface. J Biol Chem. 2017;292:14401-14412 pubmed publisher

Wurm A, Zjablovskaja P, Kardosova M, Gerloff D, Bräuer Hartmann D, Katzerke C, et al. Disruption of the C/EBP?-miR-182 balance impairs granulocytic differentiation. Nat Commun. 2017;8:46 pubmed publisher

McClatchie T, Meredith M, Ouédraogo M, Slow S, Lever M, Mann M, et al. Betaine is accumulated via transient choline dehydrogenase activation during mouse oocyte meiotic maturation. J Biol Chem. 2017;292:13784-13794 pubmed publisher

Miles L, Burga L, Gardner E, Bostina M, Poirier J, Rudin C. Anthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus. J Clin Invest. 2017;127:2957-2967 pubmed publisher

Fei T, Chen Y, Xiao T, Li W, Cato L, Zhang P, et al. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc Natl Acad Sci U S A. 2017;114:E5207-E5215 pubmed publisher

Smith S, Mellor P, Ward A, Kendall S, McDonald M, Vizeacoumar F, et al. Molecular characterization of breast cancer cell lines through multiple omic approaches. Breast Cancer Res. 2017;19:65 pubmed publisher

Suleymanova N, Crudden C, Shibano T, Worrall C, Oprea I, Tica A, et al. Functional antagonism of β-arrestin isoforms balance IGF-1R expression and signalling with distinct cancer-related biological outcomes. Oncogene. 2017;36:5734-5744 pubmed publisher

Felt S, Droby G, Grdzelishvili V. Ruxolitinib and Polycation Combination Treatment Overcomes Multiple Mechanisms of Resistance of Pancreatic Cancer Cells to Oncolytic Vesicular Stomatitis Virus. J Virol. 2017;91: pubmed publisher

Mompeán M, Romano V, Pantoja Uceda D, Stuani C, Baralle F, Buratti E, et al. Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions. J Biol Chem. 2017;292:11992-12006 pubmed publisher

Sahu S, Kumar M, Chakraborty S, Banerjee S, Kumar R, Gupta P, et al. MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling, the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection. PLoS Pathog. 2017;13:e1006410 pubmed publisher

Kim J, Toda C, Ramírez C, Fernandez Hernando C, Diano S. Hypothalamic Ventromedial Lin28a Enhances Glucose Metabolism in Diet-Induced Obesity. Diabetes. 2017;66:2102-2111 pubmed publisher

Loers G, Astafiev S, Hapiak Y, Saini V, Mishra B, Gul S, et al. The polysialic acid mimetics idarubicin and irinotecan stimulate neuronal survival and neurite outgrowth and signal via protein kinase C. J Neurochem. 2017;142:392-406 pubmed publisher

Vieira N, Spinazzola J, Alexander M, Moreira Y, Kawahara G, Gibbs D, et al. Repression of phosphatidylinositol transfer protein ? ameliorates the pathology of Duchenne muscular dystrophy. Proc Natl Acad Sci U S A. 2017;114:6080-6085 pubmed publisher

Kawasaki S, Fujita Y, Nagaike T, Tomita K, Saito H. Synthetic mRNA devices that detect endogenous proteins and distinguish mammalian cells. Nucleic Acids Res. 2017;45:e117 pubmed publisher

Nam M, Akie T, Sanosaka M, Craige S, Kant S, Keaney J, et al. Mitochondrial retrograde signaling connects respiratory capacity to thermogenic gene expression. Sci Rep. 2017;7:2013 pubmed publisher

Zaritsky A, Tseng Y, Rabadán M, Krishna S, Overholtzer M, Danuser G, et al. Diverse roles of guanine nucleotide exchange factors in regulating collective cell migration. J Cell Biol. 2017;216:1543-1556 pubmed publisher

Leikas J, Kohtala S, Theilmann W, Jalkanen A, Forsberg M, Rantamäki T. Brief isoflurane anesthesia regulates striatal AKT-GSK3? signaling and ameliorates motor deficits in a rat model of early-stage Parkinson's disease. J Neurochem. 2017;142:456-463 pubmed publisher

Gu J, Chen F, Iqbal K, Gong C, Wang X, Liu F. Transactive response DNA-binding protein 43 (TDP-43) regulates alternative splicing of tau exon 10: Implications for the pathogenesis of tauopathies. J Biol Chem. 2017;292:10600-10612 pubmed publisher

Aroor A, Habibi J, Kandikattu H, Garro Kacher M, Barron B, Chen D, et al. Dipeptidyl peptidase-4 (DPP-4) inhibition with linagliptin reduces western diet-induced myocardial TRAF3IP2 expression, inflammation and fibrosis in female mice. Cardiovasc Diabetol. 2017;16:61 pubmed publisher

Head P, Zhang H, Bastien A, Koyen A, Withers A, Daddacha W, et al. Sirtuin 2 mutations in human cancers impair its function in genome maintenance. J Biol Chem. 2017;292:9919-9931 pubmed publisher

Sokolowski M, Chynces M, Deharo D, Christian C, Belancio V. Truncated ORF1 proteins can suppress LINE-1 retrotransposition in trans. Nucleic Acids Res. 2017;45:5294-5308 pubmed publisher

Liu Y, Li L, An S, Zhang Y, Feng S, Zhao L, et al. Antifatigue Effects of Antrodia cinnamomea Cultured Mycelium via Modulation of Oxidative Stress Signaling in a Mouse Model. Biomed Res Int. 2017;2017:9374026 pubmed publisher

Lu K, Alcivar A, Ma J, Foo T, Zywea S, Mahdi A, et al. NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress-Induced DPP3-KEAP1 Interaction. Cancer Res. 2017;77:2881-2892 pubmed publisher

Wizeman J, Mohan R. Expression of peptidylarginine deiminase 4 in an alkali injury model of retinal gliosis. Biochem Biophys Res Commun. 2017;487:134-139 pubmed publisher

Li J, Xiu Z, Wang R, Yu C, Chi Y, Qin J, et al. The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPAR?. Life Sci. 2017;177:27-40 pubmed publisher

Liu Y, Wang J, Li L, Hu W, Qu Y, Ding Y, et al. Hepatoprotective Effects of Antrodia cinnamomea: The Modulation of Oxidative Stress Signaling in a Mouse Model of Alcohol-Induced Acute Liver Injury. Oxid Med Cell Longev. 2017;2017:7841823 pubmed publisher

Wasik U, Milkiewicz M, Kempińska Podhorodecka A, Milkiewicz P. Protection against oxidative stress mediated by the Nrf2/Keap1 axis is impaired in Primary Biliary Cholangitis. Sci Rep. 2017;7:44769 pubmed publisher

Moilanen J, Löffek S, Kokkonen N, Salo S, Väyrynen J, Hurskainen T, et al. Significant Role of Collagen XVII And Integrin β4 in Migration and Invasion of The Less Aggressive Squamous Cell Carcinoma Cells. Sci Rep. 2017;7:45057 pubmed publisher

Nguyen T, Li J, Lu C, Mamrosh J, Lu G, Cathers B, et al. p97/VCP promotes degradation of CRBN substrate glutamine synthetase and neosubstrates. Proc Natl Acad Sci U S A. 2017;114:3565-3571 pubmed publisher

Ferreira N, Engelsby H, Neess D, Kelly S, Volpert G, Merrill A, et al. Regulation of very-long acyl chain ceramide synthesis by acyl-CoA-binding protein. J Biol Chem. 2017;292:7588-7597 pubmed publisher

Choi M, Min Y, Pyo J, Lee C, Jang C, Kim J. TC Mps1 12, a novel Mps1 inhibitor, suppresses the growth of hepatocellular carcinoma cells via the accumulation of chromosomal instability. Br J Pharmacol. 2017;174:1810-1825 pubmed publisher

Kuo T, Chen T, Lee R, Nguyen N, Broughton A, Zhang D, et al. Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis. Diabetes. 2017;66:1601-1610 pubmed publisher

Petit M, Koziel R, Etemad S, Pircher H, Jansen Durr P. Depletion of oxaloacetate decarboxylase FAHD1 inhibits mitochondrial electron transport and induces cellular senescence in human endothelial cells. Exp Gerontol. 2017;92:7-12 pubmed publisher

Mu Y, Yan W, Yin T, Zhang Y, Li J, Yang J. Diet-induced obesity impairs spermatogenesis: a potential role for autophagy. Sci Rep. 2017;7:43475 pubmed publisher

Wang L, Cooper J. Optogenetic control of the Dab1 signaling pathway. Sci Rep. 2017;7:43760 pubmed publisher

Walker R, Czepnik M, Goebel E, McCoy J, Vujic A, Cho M, et al. Structural basis for potency differences between GDF8 and GDF11. BMC Biol. 2017;15:19 pubmed publisher

Liu Y, Liu R, Yang F, Cheng R, Chen X, Cui S, et al. miR-19a promotes colorectal cancer proliferation and migration by targeting TIA1. Mol Cancer. 2017;16:53 pubmed publisher

Liang D, Wang Z, Yan Z, Hou S, Xu W, Wang L, et al. Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module. Sci Rep. 2017;7:43798 pubmed publisher

Lerner N, Avissar S, Beit Yannai E. Extracellular vesicles mediate signaling between the aqueous humor producing and draining cells in the ocular system. PLoS ONE. 2017;12:e0171153 pubmed publisher

Kim Y, Choe S, Cho K, Cho D, Kang J, Park C, et al. Resveratrol suppresses breast cancer cell invasion by inactivating a RhoA/YAP signaling axis. Exp Mol Med. 2017;49:e296 pubmed publisher

Koide N, Kasamatsu A, Endo Sakamoto Y, Ishida S, Shimizu T, Kimura Y, et al. Evidence for Critical Role of Lymphocyte Cytosolic Protein 1 in Oral Cancer. Sci Rep. 2017;7:43379 pubmed publisher

Bakshi A, Moin M, Kumar M, Reddy A, Ren M, Datla R, et al. Ectopic expression of Arabidopsis Target of Rapamycin (AtTOR) improves water-use efficiency and yield potential in rice. Sci Rep. 2017;7:42835 pubmed publisher

An L, Hu X, Zhang S, Hu X, Song Z, Naz A, et al. UVRAG Deficiency Exacerbates Doxorubicin-Induced Cardiotoxicity. Sci Rep. 2017;7:43251 pubmed publisher

Liu Y, Xu H, Geng Y, Xu D, Zhang L, Yang Y, et al. Dibutyryl-cAMP attenuates pulmonary fibrosis by blocking myofibroblast differentiation via PKA/CREB/CBP signaling in rats with silicosis. Respir Res. 2017;18:38 pubmed publisher

Hsia H, Hutti J, Baldwin A. Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity. J Biol Chem. 2017;292:5405-5417 pubmed publisher

Barca Mayo O, Pons Espinal M, Follert P, Armirotti A, Berdondini L, De Pietri Tonelli D. Astrocyte deletion of Bmal1 alters daily locomotor activity and cognitive functions via GABA signalling. Nat Commun. 2017;8:14336 pubmed publisher

Siraj A, Masoodi T, Bu R, Pratheeshkumar P, Al Sanea N, Ashari L, et al. MED12 is recurrently mutated in Middle Eastern colorectal cancer. Gut. 2018;67:663-671 pubmed publisher

Qiu X, Pascal L, Song Q, Zang Y, Ai J, O Malley K, et al. Physical and Functional Interactions between ELL2 and RB in the Suppression of Prostate Cancer Cell Proliferation, Migration, and Invasion. Neoplasia. 2017;19:207-215 pubmed publisher

Kempińska Podhorodecka A, Milkiewicz M, Wasik U, Ligocka J, Zawadzki M, Krawczyk M, et al. Decreased Expression of Vitamin D Receptor Affects an Immune Response in Primary Biliary Cholangitis via the VDR-miRNA155-SOCS1 Pathway. Int J Mol Sci. 2017;18: pubmed publisher

Biehs R, Steinlage M, Barton O, Juhasz S, Künzel J, Spies J, et al. DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination. Mol Cell. 2017;65:671-684.e5 pubmed publisher

Cataldo L, Mizgier M, Bravo Sagua R, Jaña F, Cardenas C, Llanos P, et al. Prolonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cells. PLoS ONE. 2017;12:e0170213 pubmed publisher

Kissing S, Rudnik S, Damme M, Lüllmann Rauch R, Ichihara A, Kornak U, et al. Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes. Autophagy. 2017;13:670-685 pubmed publisher

Cai L, Wang H, Yang Q. CRKL overexpression promotes cell proliferation and inhibits apoptosis in endometrial carcinoma. Oncol Lett. 2017;13:51-56 pubmed publisher

An N, Luo X, Zhang M, Yu R. MicroRNA-376b promotes breast cancer metastasis by targeting Hoxd10 directly. Exp Ther Med. 2017;13:79-84 pubmed publisher

Lin Y, Liu H, Waraky A, Haglund F, Agarwal P, Jernberg Wiklund H, et al. SUMO-modified insulin-like growth factor 1 receptor (IGF-1R) increases cell cycle progression and cell proliferation. J Cell Physiol. 2017;232:2722-2730 pubmed publisher

Gan J, Wang F, Mu D, Qu Y, Luo R, Wang Q. RNA interference targeting Aurora-A sensitizes glioblastoma cells to temozolomide chemotherapy. Oncol Lett. 2016;12:4515-4523 pubmed publisher

Christian C, Sokolowski M, Deharo D, Kines K, Belancio V. Involvement of Conserved Amino Acids in the C-Terminal Region of LINE-1 ORF2p in Retrotransposition. Genetics. 2017;205:1139-1149 pubmed publisher

Worrall C, Suleymanova N, Crudden C, Trocoli Drakensjö I, Candrea E, Nedelcu D, et al. Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma. Oncogene. 2017;36:3274-3286 pubmed publisher

Muranen T, Iwanicki M, Curry N, Hwang J, DuBois C, Coloff J, et al. Starved epithelial cells uptake extracellular matrix for survival. Nat Commun. 2017;8:13989 pubmed publisher

Della Mina E, Borghesi A, Zhou H, Bougarn S, Boughorbel S, Israel L, et al. Inherited human IRAK-1 deficiency selectively impairs TLR signaling in fibroblasts. Proc Natl Acad Sci U S A. 2017;114:E514-E523 pubmed publisher

Kleinsimon S, Kauczor G, Jaeger S, Eggert A, Seifert G, Delebinski C. ViscumTT induces apoptosis and alters IAP expression in osteosarcoma in vitro and has synergistic action when combined with different chemotherapeutic drugs. BMC Complement Altern Med. 2017;17:26 pubmed publisher

Rai V, Thomas D, Beach J, Egelhoff T. Myosin IIA Heavy Chain Phosphorylation Mediates Adhesion Maturation and Protrusion in Three Dimensions. J Biol Chem. 2017;292:3099-3111 pubmed publisher

Chew W, Tabebordbar M, Cheng J, Mali P, Wu E, Ng A, et al. A multifunctional AAV-CRISPR-Cas9 and its host response. Nat Methods. 2016;13:868-74 pubmed publisher

Liu Z, Hui Y, Shi L, Chen Z, Xu X, Chi L, et al. Efficient CRISPR/Cas9-Mediated Versatile, Predictable, and Donor-Free Gene Knockout in Human Pluripotent Stem Cells. Stem Cell Reports. 2016;7:496-507 pubmed publisher

Cunningham C, Li S, Vizeacoumar F, Bhanumathy K, Lee J, Parameswaran S, et al. Therapeutic relevance of the protein phosphatase 2A in cancer. Oncotarget. 2016;7:61544-61561 pubmed publisher

Matkar P, Singh K, Rudenko D, Kim Y, Kuliszewski M, Prud homme G, et al. Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma. Oncotarget. 2016;7:69489-69506 pubmed publisher

Hastie E, Cataldi M, Moerdyk Schauwecker M, Felt S, Steuerwald N, Grdzelishvili V. Novel biomarkers of resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus. Oncotarget. 2016;7:61601-61618 pubmed publisher

Riascos Bernal D, Chinnasamy P, Cao L, Dunaway C, Valenta T, Basler K, et al. β-Catenin C-terminal signals suppress p53 and are essential for artery formation. Nat Commun. 2016;7:12389 pubmed publisher

Crippa V, Cicardi M, Ramesh N, Seguin S, Ganassi M, Bigi I, et al. The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity. Hum Mol Genet. 2016;25:3908-3924 pubmed publisher

Saisana M, Griffin S, May F. Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation. Oncotarget. 2016;7:54445-54462 pubmed publisher

Pratheeshkumar P, Son Y, Divya S, Turcios L, Roy R, Hitron J, et al. Hexavalent chromium induces malignant transformation of human lung bronchial epithelial cells via ROS-dependent activation of miR-21-PDCD4 signaling. Oncotarget. 2016;7:51193-51210 pubmed publisher

Liu Z, Lam N, Wang E, Virden R, Pawel B, Attiyeh E, et al. Identification of CASZ1 NES reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma. Oncogene. 2017;36:97-109 pubmed publisher

Yu J, Liang Q, Wang J, Wang K, Gao J, Zhang J, et al. REC8 functions as a tumor suppressor and is epigenetically downregulated in gastric cancer, especially in EBV-positive subtype. Oncogene. 2017;36:182-193 pubmed publisher

Christian C, Deharo D, Kines K, Sokolowski M, Belancio V. Identification of L1 ORF2p sequence important to retrotransposition using Bipartile Alu retrotransposition (BAR). Nucleic Acids Res. 2016;44:4818-34 pubmed publisher

Li M, Andersson Lendahl M, Sejersen T, Arner A. Knockdown of fast skeletal myosin-binding protein C in zebrafish results in a severe skeletal myopathy. J Gen Physiol. 2016;147:309-22 pubmed publisher

Jin H, Lee K, Kim Y, Oh H, Maeng Y, Kim T, et al. Scaffold protein FHL2 facilitates MDM2-mediated degradation of IER3 to regulate proliferation of cervical cancer cells. Oncogene. 2016;35:5106-18 pubmed publisher

Locard Paulet M, Lim L, Veluscek G, McMahon K, Sinclair J, van Weverwijk A, et al. Phosphoproteomic analysis of interacting tumor and endothelial cells identifies regulatory mechanisms of transendothelial migration. Sci Signal. 2016;9:ra15 pubmed publisher

Thornton T, Delgado P, Chen L, Salas B, Krementsov D, Fernández M, et al. Inactivation of nuclear GSK3β by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break response. Nat Commun. 2016;7:10553 pubmed publisher

Ying M, Zhang L, Zhou Q, Shao X, Cao J, Zhang N, et al. The E3 ubiquitin protein ligase MDM2 dictates all-trans retinoic acid-induced osteoblastic differentiation of osteosarcoma cells by modulating the degradation of RARα. Oncogene. 2016;35:4358-67 pubmed publisher

Liu Z, Skamagki M, Kim K, Zhao R. Canonical MicroRNA Activity Facilitates but May Be Dispensable for Transcription Factor-Mediated Reprogramming. Stem Cell Reports. 2015;5:1119-1127 pubmed publisher

Omori Y, Mano T, Ohtani T, Sakata Y, Takeda Y, Tamaki S, et al. Glucocorticoids Induce Cardiac Fibrosis via Mineralocorticoid Receptor in Oxidative Stress: Contribution of Elongation Factor Eleven-Nineteen Lysine-Rich Leukemia (ELL). Yonago Acta Med. 2014;57:109-16 pubmed

Jacobshagen M, Niquille M, Chaumont Dubel S, Marin P, Dayer A. The serotonin 6 receptor controls neuronal migration during corticogenesis via a ligand-independent Cdk5-dependent mechanism. Development. 2014;141:3370-7 pubmed publisher

Koch L, Schmitz V, Strassburg C, Raskopf E. Plasmid transfer of plasminogen K1-5 reduces subcutaneous hepatoma growth by affecting inflammatory factors. Biomed Res Int. 2014;2014:656527 pubmed publisher

Wang J, Ben Hamida S, Darcq E, Zhu W, Gibb S, Lanfranco M, et al. Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior. J Neurosci. 2012;32:15124-32 pubmed publisher

Filipe Santos O, Bustamante J, Haverkamp M, Vinolo E, Ku C, Puel A, et al. X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production. J Exp Med. 2006;203:1745-59 pubmed