product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
52 kDa Ro/SSA (D-12) Antibody
catalog :
sc-25351
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D-12
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, western blot knockout validation
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; 1:1000; loading ...; fig s1a
Bottermann M, Foss S, Caddy S, Clift D, van Tienen L, Vaysburd M, et al. Complement C4 Prevents Viral Infection through Capsid Inactivation. Cell Host Microbe. 2019;25:617-629.e7 pubmed publisher
  • western blot; human; loading ...; fig 6b
Cao X, Zhou Z, Tian Y, Liu Z, Cheng K, Chen X, et al. Opposing roles of E3 ligases TRIM23 and TRIM21 in regulation of ion channel ANO1 protein levels. J Biol Chem. 2021;296:100738 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 3a
Zhao Z, Wang Y, Yun D, Huang Q, Meng D, Li Q, et al. TRIM21 overexpression promotes tumor progression by regulating cell proliferation, cell migration and cell senescence in human glioma. Am J Cancer Res. 2020;10:114-130 pubmed
  • western blot; human; loading ...; fig 4d
Xu D, Li X, Shao F, Lv G, Lv H, Lee J, et al. The protein kinase activity of fructokinase A specifies the antioxidant responses of tumor cells by phosphorylating p62. Sci Adv. 2019;5:eaav4570 pubmed publisher
  • western blot; human; loading ...; fig 5c
Agod Z, Pazmandi K, Bencze D, Vereb G, Biro T, Szabo A, et al. Signaling Lymphocyte Activation Molecule Family 5 Enhances Autophagy and Fine-Tunes Cytokine Response in Monocyte-Derived Dendritic Cells via Stabilization of Interferon Regulatory Factor 8. Front Immunol. 2018;9:62 pubmed publisher
  • western blot; human; 1:1000; fig 5
Du L, LI Y, Fakih M, Wiatrek R, Duldulao M, Chen Z, et al. Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal. Nat Commun. 2016;7:12326 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Pankow S, Bamberger C, Calzolari D, Martínez Bartolomé S, Lavallée Adam M, Balch W, et al. ∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis. Nature. 2015;528:510-6 pubmed publisher
  • western blot; human; fig 7
Watkinson R, McEwan W, Tam J, Vaysburd M, James L. TRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus. PLoS Pathog. 2015;11:e1005253 pubmed publisher
  • western blot; human
Vogelsang P, Karlsen M, Brun J, Jonsson R, Appel S. Altered phenotype and Stat1 expression in Toll-like receptor 7/8 stimulated monocyte-derived dendritic cells from patients with primary Sjögren's syndrome. Arthritis Res Ther. 2014;16:R166 pubmed publisher
Kong W, Hayashi T, Fiches G, Xu Q, Li M, Que J, et al. Diversified Application of Barcoded PLATO (PLATO-BC) Platform for Identification of Protein Interactions. Genomics Proteomics Bioinformatics. 2019;17:319-331 pubmed publisher
Lee J, Haddon D, Wand H, Price J, Diep V, Hall D, et al. Multiplex giant magnetoresistive biosensor microarrays identify interferon-associated autoantibodies in systemic lupus erythematosus. Sci Rep. 2016;6:27623 pubmed publisher
Manocha G, Mishra R, Sharma N, Kumawat K, Basu A, Singh S. Regulatory role of TRIM21 in the type-I interferon pathway in Japanese encephalitis virus-infected human microglial cells. J Neuroinflammation. 2014;11:24 pubmed publisher
Hauler F, Mallery D, McEwan W, Bidgood S, James L. AAA ATPase p97/VCP is essential for TRIM21-mediated virus neutralization. Proc Natl Acad Sci U S A. 2012;109:19733-8 pubmed publisher
Mallery D, McEwan W, Bidgood S, Towers G, Johnson C, James L. Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21). Proc Natl Acad Sci U S A. 2010;107:19985-90 pubmed publisher
Tanaka M, Tanji K, Niida M, Kamitani T. Dynamic movements of Ro52 cytoplasmic bodies along microtubules. Histochem Cell Biol. 2010;133:273-84 pubmed publisher
product information
Catalog Number :
sc-25351
Product Name :
52 kDa Ro/SSA (D-12) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
D-12
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
52 kDa Ro/SSA
Specificity :
human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA