product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
vinculin (H-10) Antibody
catalog :
sc-25336
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H-10
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 34
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 1h
Su S, Chen J, Jiang Y, Wang Y, Vital T, Zhang J, et al. SPOP and OTUD7A Control EWS-FLI1 Protein Stability to Govern Ewing Sarcoma Growth. Adv Sci (Weinh). 2021;8:e2004846 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3h
Cheung E, DeNicola G, Nixon C, Blyth K, Labuschagne C, Tuveson D, et al. Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer. Cancer Cell. 2020;37:168-182.e4 pubmed publisher
  • western blot; human; loading ...; fig 1b
Barbero G, Castro M, Villanueva M, Quezada M, Fernández N, Demorrow S, et al. An Autocrine Wnt5a Loop Promotes NF-κB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma. Cells. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig 1b
SCHADE A, Oser M, Nicholson H, DeCaprio J. Cyclin D-CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB. Oncogene. 2019;38:4962-4976 pubmed publisher
  • western blot; human; loading ...; fig 1b
Kais Z, Rondinelli B, Holmes A, O Leary C, Kozono D, D Andrea A, et al. FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair. Cell Rep. 2016;15:2488-99 pubmed publisher
  • western blot; human; 1:1000; fig 2
Tsang Y, Dogruluk T, Tedeschi P, Wardwell Ozgo J, Lu H, Espitia M, et al. Functional annotation of rare gene aberration drivers of pancreatic cancer. Nat Commun. 2016;7:10500 pubmed publisher
  • western blot; human; 1:1000; fig 1
de Lange J, Faramarz A, Oostra A, de Menezes R, van der Meulen I, Rooimans M, et al. Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function. Nat Commun. 2015;6:8399 pubmed publisher
  • western blot; human; 1:1000; fig 3
Kushwaha D, O Leary C, Cron K, Deraska P, Zhu K, D Andrea A, et al. USP9X inhibition promotes radiation-induced apoptosis in non-small cell lung cancer cells expressing mid-to-high MCL1. Cancer Biol Ther. 2015;16:392-401 pubmed publisher
  • immunocytochemistry; human; fig 5
Ward J, Ha J, Jayaraman M, Dhanasekaran D. LPA-mediated migration of ovarian cancer cells involves translocalization of Gαi2 to invadopodia and association with Src and β-pix. Cancer Lett. 2015;356:382-91 pubmed publisher
de la Cruz Herrera C, Tatham M, Siddiqi U, Shire K, Marcon E, Greenblatt J, et al. Changes in SUMO-modified proteins in Epstein-Barr virus infection identifies reciprocal regulation of TRIM24/28/33 complexes and the lytic switch BZLF1. PLoS Pathog. 2023;19:e1011477 pubmed publisher
Hsieh E, Janssens D, Paddison P, Browne E, Henikoff S, OhAinle M, et al. A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency. PLoS Pathog. 2023;19:e1011101 pubmed publisher
Pedrazza L, Martinez Martinez A, S xe1 nchez de Diego C, Valer J, Pimenta Lopes C, Sala Gaston J, et al. HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling. Cell Death Dis. 2023;14:17 pubmed publisher
Schleicher E, Dhoonmoon A, Jackson L, Khatib J, Nicolae C, Moldovan G. The TIP60-ATM axis regulates replication fork stability in BRCA-deficient cells. Oncogenesis. 2022;11:33 pubmed publisher
Bakr A, Hey J, Sigismondo G, Liu C, Sadik A, Goyal A, et al. ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition. Nucleic Acids Res. 2021;49:11666-11689 pubmed publisher
Clements K, Schleicher E, Thakar T, Hale A, Dhoonmoon A, Tolman N, et al. Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens. Nat Commun. 2020;11:6118 pubmed publisher
van Schie J, Faramarz A, Balk J, Stewart G, Cantelli E, Oostra A, et al. Warsaw Breakage Syndrome associated DDX11 helicase resolves G-quadruplex structures to support sister chromatid cohesion. Nat Commun. 2020;11:4287 pubmed publisher
Mayor Ruiz C, Bauer S, Brand M, Kozicka Z, Siklos M, Imrichová H, et al. Rational discovery of molecular glue degraders via scalable chemical profiling. Nat Chem Biol. 2020;: pubmed publisher
Anania S, Peiffer R, Rademaker G, Hego A, Thiry M, Deldicque L, et al. Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics' Machinery in Pancreas Cancer Cells. Cancers (Basel). 2020;12: pubmed publisher
Verdura S, Cuyàs E, Cortada E, Brunet J, Lopez Bonet E, Martin Castillo B, et al. Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity. Aging (Albany NY). 2020;12:8-34 pubmed publisher
Liu T, Han Y, Yu C, Ji Y, Wang C, Chen X, et al. MYC predetermines the sensitivity of gastrointestinal cancer to antifolate drugs through regulating TYMS transcription. EBioMedicine. 2019;48:289-300 pubmed publisher
Haque M, Li J, Huang Y, Almowaled M, Barger C, Karpf A, et al. NPM-ALK Is a Key Regulator of the Oncoprotein FOXM1 in ALK-Positive Anaplastic Large Cell Lymphoma. Cancers (Basel). 2019;11: pubmed publisher
Fukumoto T, Zhu H, Nacarelli T, Karakashev S, Fatkhutdinov N, Wu S, et al. N6-Methylation of Adenosine of FZD10 mRNA Contributes to PARP Inhibitor Resistance. Cancer Res. 2019;79:2812-2820 pubmed publisher
Xiong L, Wu F, Wu Q, Xu L, Cheung O, Kang W, et al. Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming. Nat Commun. 2019;10:335 pubmed publisher
Bonacci T, Suzuki A, Grant G, Stanley N, Cook J, Brown N, et al. Cezanne/OTUD7B is a cell cycle-regulated deubiquitinase that antagonizes the degradation of APC/C substrates. EMBO J. 2018;37: pubmed publisher
Nabet B, Roberts J, Buckley D, Paulk J, Dastjerdi S, Yang A, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018;14:431-441 pubmed publisher
Gechijian L, Buckley D, Lawlor M, Reyes J, Paulk J, Ott C, et al. Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands. Nat Chem Biol. 2018;14:405-412 pubmed publisher
Zeid R, Lawlor M, Poon E, Reyes J, Fulciniti M, Lopez M, et al. Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma. Nat Genet. 2018;50:515-523 pubmed publisher
Castaño E, Caviedes L, Hirsch S, Llanos M, Iniguez G, Ronco A. Folate Transporters in Placentas from Preterm Newborns and Their Relation to Cord Blood Folate and Vitamin B12 Levels. PLoS ONE. 2017;12:e0170389 pubmed publisher
Ceccaldi R, Liu J, Amunugama R, Hajdu I, Primack B, Petalcorin M, et al. Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair. Nature. 2015;518:258-62 pubmed publisher
Cron K, Zhu K, Kushwaha D, Hsieh G, Merzon D, Rameseder J, et al. Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer. PLoS ONE. 2013;8:e73710 pubmed publisher
Knies K, Schuster B, Ameziane N, Rooimans M, Bettecken T, de Winter J, et al. Genotyping of fanconi anemia patients by whole exome sequencing: advantages and challenges. PLoS ONE. 2012;7:e52648 pubmed publisher
Logotheti S, Papaevangeliou D, Michalopoulos I, Sideridou M, Tsimaratou K, Christodoulou I, et al. Progression of mouse skin carcinogenesis is associated with increased ER? levels and is repressed by a dominant negative form of ER?. PLoS ONE. 2012;7:e41957 pubmed publisher
Chng K, Chang C, Tan S, Yang C, Hong S, Sng N, et al. A transcriptional repressor co-regulatory network governing androgen response in prostate cancers. EMBO J. 2012;31:2810-23 pubmed publisher
Chen C, Kennedy R, Sidi S, Look A, D ANDREA A. CHK1 inhibition as a strategy for targeting Fanconi Anemia (FA) DNA repair pathway deficient tumors. Mol Cancer. 2009;8:24 pubmed publisher
product information
Catalog Number :
sc-25336
Product Name :
vinculin (H-10) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
H-10
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
vinculin
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA