product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Topo IIβ (H-8) Antibody
catalog :
sc-25330
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H-8
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:300; loading ...; fig 4b
Li Y, Hao H, Swerdel M, Cho H, Lee K, Hart R, et al. Top2b is involved in the formation of outer segment and synapse during late-stage photoreceptor differentiation by controlling key genes of photoreceptor transcriptional regulatory network. J Neurosci Res. 2017;95:1951-1964 pubmed publisher
  • western blot; human; 1:1000
Kong L, Wei J, Haider A, Liebelt B, Ling X, Conrad C, et al. Therapeutic targets in subependymoma. J Neuroimmunol. 2014;277:168-75 pubmed publisher
  • immunohistochemistry; mouse; fig 3
  • western blot; mouse; fig 3
  • immunohistochemistry; human; fig 3
  • western blot; human; fig 3
Zhang H, Zhang Y, Yasukawa T, Dalla Rosa I, Khiati S, Pommier Y. Increased negative supercoiling of mtDNA in TOP1mt knockout mice and presence of topoisomerases II? and II? in vertebrate mitochondria. Nucleic Acids Res. 2014;42:7259-67 pubmed publisher
  • western blot; mouse
Wang R, Wang Y, Gao Z, Qu X. The comparative study of acetyl-11-keto-beta-boswellic acid (AKBA) and aspirin in the prevention of intestinal adenomatous polyposis in APC(Min/+) mice. Drug Discov Ther. 2014;8:25-32 pubmed
Bunch H, Kim D, Naganuma M, Nakagawa R, Cong A, Jeong J, et al. ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes. Nat Commun. 2023;14:8341 pubmed publisher
Bunch H, Jeong J, Kang K, Jo D, Cong A, Kim D, et al. BRCA1-BARD1 regulates transcription through modulating topoisomerase IIβ. Open Biol. 2021;11:210221 pubmed publisher
Khiati S, Dalla Rosa I, Sourbier C, Ma X, Rao V, Neckers L, et al. Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity. Clin Cancer Res. 2014;20:4873-81 pubmed publisher
Niu X, Zhang T, Liao L, Zhou L, Lindner D, Zhou M, et al. The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C. Oncogene. 2012;31:776-86 pubmed publisher
product information
Catalog Number :
sc-25330
Product Name :
Topo IIβ (H-8) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
H-8
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Topo IIbeta
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA