product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
LRP6 (C-10) Antibody
catalog :
sc-25317
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-10
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:50; fig s1-1c
Ortiz Cordero C, Magli A, Dhoke N, Kuebler T, Selvaraj S, Oliveira N, et al. NAD+ enhances ribitol and ribose rescue of α-dystroglycan functional glycosylation in human FKRP-mutant myotubes. elife. 2021;10: pubmed publisher
  • western blot; human; loading ...; fig s3i
Wang H, Nicolay B, Chick J, Gao X, Geng Y, Ren H, et al. The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival. Nature. 2017;546:426-430 pubmed publisher
  • immunoprecipitation; mouse; loading ...; fig 5c
  • immunohistochemistry; mouse; 1:50; loading ...; fig s6e
  • western blot; mouse; 1:500; loading ...; fig s7b
  • immunocytochemistry; human; 1:500; loading ...; fig s6f
Lian G, Dettenhofer M, Lu J, Downing M, Chenn A, Wong T, et al. Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway. Development. 2016;143:4509-4520 pubmed
  • western blot; human; fig 2
Guo J, Li Y, Ren Y, Sun Z, Dong J, Yan H, et al. Mutant LRP6 Impairs Endothelial Cell Functions Associated with Familial Normolipidemic Coronary Artery Disease. Int J Mol Sci. 2016;17: pubmed publisher
  • western blot; human; fig s2
Ozeki N, Mogi M, Hase N, Hiyama T, Yamaguchi H, Kawai R, et al. Wnt16 Signaling Is Required for IL-1β-Induced Matrix Metalloproteinase-13-Regulated Proliferation of Human Stem Cell-Derived Osteoblastic Cells. Int J Mol Sci. 2016;17:221 pubmed publisher
Cha B, Geng X, Mahamud M, Zhang J, Chen L, Kim W, et al. Complementary Wnt Sources Regulate Lymphatic Vascular Development via PROX1-Dependent Wnt/β-Catenin Signaling. Cell Rep. 2018;25:571-584.e5 pubmed publisher
Huang M, Qi W, Fang S, Jiang P, Yang C, Mo Y, et al. Pigment Epithelium-Derived Factor Plays a Role in Alzheimer's Disease by Negatively Regulating Aβ42. Neurotherapeutics. 2018;15:728-741 pubmed publisher
Liu X, Fagotto F. A method to separate nuclear, cytosolic, and membrane-associated signaling molecules in cultured cells. Sci Signal. 2011;4:pl2 pubmed publisher
Zhang L, Zhou F, van Laar T, Zhang J, van Dam H, Ten Dijke P. Fas-associated factor 1 antagonizes Wnt signaling by promoting ?-catenin degradation. Mol Biol Cell. 2011;22:1617-24 pubmed publisher
Honda T, Yamamoto H, Ishii A, Inui M. PDZRN3 negatively regulates BMP-2-induced osteoblast differentiation through inhibition of Wnt signaling. Mol Biol Cell. 2010;21:3269-77 pubmed publisher
Chen M, Philipp M, Wang J, Premont R, Garrison T, Caron M, et al. G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway. J Biol Chem. 2009;284:35040-8 pubmed publisher
product information
Catalog Number :
sc-25317
Product Name :
LRP6 (C-10) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
C-10
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
LRP6
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA