product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
FXR (D-3) Antibody
catalog :
sc-25309
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D-3
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 5
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...; fig 2a
  • immunocytochemistry; human; 1:100; loading ...; fig 4b
  • western blot; human; loading ...; fig 1c
Yu J, Yang K, Zheng J, Zhao P, Xia J, Sun X, et al. Activation of FXR and inhibition of EZH2 synergistically inhibit colorectal cancer through cooperatively accelerating FXR nuclear location and upregulating CDX2 expression. Cell Death Dis. 2022;13:388 pubmed publisher
Balasubramaniyan N, Luo Y, Sun A, Suchy F. SUMOylation of the farnesoid X receptor (FXR) regulates the expression of FXR target genes. J Biol Chem. 2013;288:13850-62 pubmed publisher
Balasubramaniyan N, Ananthanarayanan M, Suchy F. Direct methylation of FXR by Set7/9, a lysine methyltransferase, regulates the expression of FXR target genes. Am J Physiol Gastrointest Liver Physiol. 2012;302:G937-47 pubmed publisher
Purushotham A, Xu Q, Lu J, Foley J, Yan X, Kim D, et al. Hepatic deletion of SIRT1 decreases hepatocyte nuclear factor 1?/farnesoid X receptor signaling and induces formation of cholesterol gallstones in mice. Mol Cell Biol. 2012;32:1226-36 pubmed publisher
Chen F, Ellis E, Strom S, Shneider B. ATPase Class I Type 8B Member 1 and protein kinase C zeta induce the expression of the canalicular bile salt export pump in human hepatocytes. Pediatr Res. 2010;67:183-7 pubmed publisher
product information
Catalog Number :
sc-25309
Product Name :
FXR (D-3) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
D-3
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
FXR
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA