product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
PCNA (F-2) Antibody
catalog :
sc-25280
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
F-2
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 72
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; loading ...; fig 6a
Wang H, Gong P, Chen T, Gao S, Wu Z, Wang X, et al. Colorectal Cancer Stem Cell States Uncovered by Simultaneous Single-Cell Analysis of Transcriptome and Telomeres. Adv Sci (Weinh). 2021;8:2004320 pubmed publisher
  • western blot; rat; loading ...; fig s5b
Du J, Yu Q, Liu Y, Du S, Huang L, Xu D, et al. A novel role of kallikrein-related peptidase 8 in the pathogenesis of diabetic cardiac fibrosis. Theranostics. 2021;11:4207-4231 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2d
Ge W, Tan S, Wang S, Li L, Sun X, Shen W, et al. Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development. Theranostics. 2020;10:7581-7598 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2a
Huang G, Liu L, Wang H, Gou M, Gong P, Tian C, et al. Tet1 Deficiency Leads to Premature Reproductive Aging by Reducing Spermatogonia Stem Cells and Germ Cell Differentiation. iScience. 2020;23:100908 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4b
Long J, Idoko Akoh A, Mistry B, Goldhill D, Staller E, Schreyer J, et al. Species specific differences in use of ANP32 proteins by influenza A virus. elife. 2019;8: pubmed publisher
  • immunohistochemistry - paraffin section; rat; loading ...; fig 5c
Qin D, Yan Y, Hu B, Zhang W, Li H, Li X, et al. Wisp2 disruption represses Cxcr4 expression and inhibits BMSCs homing to injured liver. Oncotarget. 2017;8:98823-98836 pubmed publisher
  • western blot; mouse; loading ...; fig 3f
Guo H, Kazadaeva Y, Ortega F, Manjunath N, Desai T. Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung. Dev Biol. 2017;430:214-223 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4c
Jiang C, Diao F, Sang Y, Xu N, Zhu R, Wang X, et al. GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary. PLoS Genet. 2017;13:e1006535 pubmed publisher
  • western blot; human; fig 2c
Liao X, Li J, Dong X, Wang X, Xiang Y, Li H, et al. ER? inhibited myocardin-induced differentiation in uterine fibroids. Exp Cell Res. 2017;350:73-82 pubmed publisher
  • western blot; human; loading ...; fig 1a
Chen Y, Wang X, Duan C, Chen J, Su M, Jin Y, et al. Loss of TAB3 expression by shRNA exhibits suppressive bioactivity and increased chemical sensitivity of ovarian cancer cell lines via the NF-?B pathway. Cell Prolif. 2016;49:657-668 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 4b
Shi Y, He Z, Jia Z, Xu C. Inhibitory effect of metformin combined with gemcitabine on pancreatic cancer cells in vitro and in vivo. Mol Med Rep. 2016;14:2921-8 pubmed publisher
  • western blot; human; fig 4
Li C, Li Q, Cai Y, He Y, Lan X, Wang W, et al. Overexpression of angiopoietin 2 promotes the formation of oral squamous cell carcinoma by increasing epithelial-mesenchymal transition-induced angiogenesis. Cancer Gene Ther. 2016;23:295-302 pubmed publisher
  • immunohistochemistry; human; 1:100; loading ...; fig 4a
Fang W, Yao M, Brummer G, Acevedo D, Alhakamy N, Berkland C, et al. Targeted gene silencing of CCL2 inhibits triple negative breast cancer progression by blocking cancer stem cell renewal and M2 macrophage recruitment. Oncotarget. 2016;7:49349-49367 pubmed publisher
  • western blot; rat; fig 5c
Lin Y, Warren C, Li J, McKinsey T, Russell B. Myofibril growth during cardiac hypertrophy is regulated through dual phosphorylation and acetylation of the actin capping protein CapZ. Cell Signal. 2016;28:1015-24 pubmed publisher
  • western blot; human; loading ...; fig 2b
Cereijo R, Gallego Escuredo J, Moure R, Villarroya J, Domingo J, Fontdevila J, et al. The Molecular Signature of HIV-1-Associated Lipomatosis Reveals Differential Involvement of Brown and Beige/Brite Adipocyte Cell Lineages. PLoS ONE. 2015;10:e0136571 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 6a
Li Y, Zhou Q, Hu Z, Yang B, Li Q, Wang J, et al. 5-Aminolevulinic Acid-Based Sonodynamic Therapy Induces the Apoptosis of Osteosarcoma in Mice. PLoS ONE. 2015;10:e0132074 pubmed publisher
  • western blot; human
  • western blot; mouse
Holtzhausen A, Zhao F, Evans K, Tsutsui M, Orabona C, Tyler D, et al. Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy. Cancer Immunol Res. 2015;3:1082-95 pubmed publisher
  • western blot; human
Cannito S, Turato C, Paternostro C, Biasiolo A, Colombatto S, Cambieri I, et al. Hypoxia up-regulates SERPINB3 through HIF-2α in human liver cancer cells. Oncotarget. 2015;6:2206-21 pubmed
  • western blot; rat; 1:5000; fig 2
Gulec S, Collins J. Silencing of the Menkes copper-transporting ATPase (Atp7a) gene increases cyclin D1 protein expression and impairs proliferation of rat intestinal epithelial (IEC-6) cells. J Trace Elem Med Biol. 2014;28:459-64 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Son A, Sheleg M, Cooper M, Sun Y, Kleiman N, Zhou R. Formation of persistent hyperplastic primary vitreous in ephrin-A5-/- mice. Invest Ophthalmol Vis Sci. 2014;55:1594-606 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400
  • western blot; mouse
Yuan J, Zhang D, Wang L, Liu M, Mao J, Yin Y, et al. No evidence for neo-oogenesis may link to ovarian senescence in adult monkey. Stem Cells. 2013;31:2538-50 pubmed publisher
Wang Y, Ma B, Liu X, Gao G, Che Z, Fan M, et al. ZFP281-BRCA2 prevents R-loop accumulation during DNA replication. Nat Commun. 2022;13:3493 pubmed publisher
Yu W, Hua Y, Qiu H, Hao J, Zou K, Li Z, et al. PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer. Cell Death Dis. 2020;11:506 pubmed publisher
Dutta P, Islam S, Choppara S, Sengupta P, Kumar A, Kumar A, et al. The tumor suppressor FBXO31 preserves genomic integrity by regulating DNA replication and segregation through precise control of cyclin A levels. J Biol Chem. 2019;294:14879-14895 pubmed publisher
Tocci P, Cianfrocca R, Di Castro V, Rosanò L, Sacconi A, Donzelli S, et al. β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer. Nat Commun. 2019;10:3196 pubmed publisher
Luan P, Jian W, Xu X, Kou W, Yu Q, Hu H, et al. NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ. Nat Commun. 2019;10:2882 pubmed publisher
Mitra S, Sharma P, Kaur S, Khursheed M, Gupta S, Chaudhary M, et al. Dual regulation of lin28a by Myc is necessary during zebrafish retina regeneration. J Cell Biol. 2019;218:489-507 pubmed publisher
Yang T, Zhang W, Xiao C, Wang L, Gong Y, Huang D, et al. Co-culture of dendritic cells and cytokine-induced killer cells effectively suppresses liver cancer stem cell growth by inhibiting pathways in the immune system. BMC Cancer. 2018;18:984 pubmed publisher
Wang X, Cui X, Zhu C, Li M, Zhao J, Shen Z, et al. FKBP11 protects intestinal epithelial cells against inflammation‑induced apoptosis via the JNK‑caspase pathway in Crohn's disease. Mol Med Rep. 2018;18:4428-4438 pubmed publisher
Rodríguez Uribe G, Serafín Higuera N, Damian Morales G, Cortés Malagón E, García Hernández V, Verdejo Torres O, et al. HPV16-E6 Oncoprotein Activates TGF-β and Wnt/β-Catenin Pathways in the Epithelium-Mesenchymal Transition of Cataracts in a Transgenic Mouse Model. Biomed Res Int. 2018;2018:2847873 pubmed publisher
Achilleos C, Michael S, Strati K. Terc is dispensable for most of the short-term HPV16 oncogene-mediated phenotypes in mice. PLoS ONE. 2018;13:e0196604 pubmed publisher
Zhenilo S, Deyev I, Litvinova E, Zhigalova N, Kaplun D, Sokolov A, et al. DeSUMOylation switches Kaiso from activator to repressor upon hyperosmotic stress. Cell Death Differ. 2018;25:1938-1951 pubmed publisher
Yun J, Park M, Son D, Nam K, Moon D, Ju J, et al. IL-32 gamma reduces lung tumor development through upregulation of TIMP-3 overexpression and hypomethylation. Cell Death Dis. 2018;9:306 pubmed publisher
Gupta G, Agrawal T, Rai V, Del Core M, Hunter W, Agrawal D. Vitamin D Supplementation Reduces Intimal Hyperplasia and Restenosis following Coronary Intervention in Atherosclerotic Swine. PLoS ONE. 2016;11:e0156857 pubmed publisher
Luciani Torres M, Moore D, Goodson W, Dairkee S. Exposure to the polyester PET precursor--terephthalic acid induces and perpetuates DNA damage-harboring non-malignant human breast cells. Carcinogenesis. 2015;36:168-76 pubmed publisher
Shen T, Ma J, Zhang L, Yu X, Liu M, Hou Y, et al. Positive feedback-loop of telomerase reverse transcriptase and 15-lipoxygenase-2 promotes pulmonary hypertension. PLoS ONE. 2013;8:e83132 pubmed publisher
Kraemer A, Barjaktarovic Z, Sarioglu H, Winkler K, Eckardt Schupp F, Tapio S, et al. Cell survival following radiation exposure requires miR-525-3p mediated suppression of ARRB1 and TXN1. PLoS ONE. 2013;8:e77484 pubmed publisher
Zhang C, Guo L, Zhu B, Feng Y, Yu S, An N, et al. Effects of 3, 5, 3'-triiodothyronine (t3) and follicle stimulating hormone on apoptosis and proliferation of rat ovarian granulosa cells. Chin J Physiol. 2013;56:298-305 pubmed publisher
Salleh N, Helmy M, Fadila K, Yeong S. Isoflavone genistein induces fluid secretion and morphological changes in the uteri of post-pubertal rats. Int J Med Sci. 2013;10:665-75 pubmed publisher
Li H, Huang D, Gao Z, Chen Y, Zhang L, Zheng J. Scutellarin inhibits the growth and invasion of human tongue squamous carcinoma through the inhibition of matrix metalloproteinase-2 and -9 and ?v?6 integrin. Int J Oncol. 2013;42:1674-81 pubmed publisher
Li H, Fan H, Wang Z, Zheng J, Cao W. Potentiation of scutellarin on human tongue carcinoma xenograft by low-intensity ultrasound. PLoS ONE. 2013;8:e59473 pubmed publisher
Guasti L, Candy Sze W, McKay T, Grose R, King P. FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development. Mol Cell Endocrinol. 2013;371:182-8 pubmed publisher
Araújo T, de Oliveira A, Tobar N, Saad M, Moreira L, Reis E, et al. Liver regeneration following partial hepatectomy is improved by enhancing the HGF/Met axis and Akt and Erk pathways after low-power laser irradiation in rats. Lasers Med Sci. 2013;28:1511-7 pubmed publisher
Chairuangkitti P, Lawanprasert S, Roytrakul S, Aueviriyavit S, Phummiratch D, Kulthong K, et al. Silver nanoparticles induce toxicity in A549 cells via ROS-dependent and ROS-independent pathways. Toxicol In Vitro. 2013;27:330-8 pubmed publisher
Gupta G, Agrawal T, Del Core M, Hunter W, Agrawal D. Decreased expression of vitamin D receptors in neointimal lesions following coronary artery angioplasty in atherosclerotic swine. PLoS ONE. 2012;7:e42789 pubmed publisher
Wu Y, Wang N, Gu L, Yang H, Xia N, Zhang H. The suppressive effect of metabotropic glutamate receptor 5 (mGlu5) inhibition on hepatocarcinogenesis. Biochimie. 2012;94:2366-75 pubmed publisher
Kim S, Song J. Therapeutic targeting of oncogenic transforming growth factor-?1 signaling by antisense oligonucleotides in oral squamous cell carcinoma. Oncol Rep. 2012;28:539-44 pubmed publisher
Zhang W, Khatibi N, Yamaguchi Okada M, Yan J, Chen C, Hu Q, et al. Mammalian target of rapamycin (mTOR) inhibition reduces cerebral vasospasm following a subarachnoid hemorrhage injury in canines. Exp Neurol. 2012;233:799-806 pubmed publisher
Berdiel Acer M, Bohem M, Lopez Doriga A, Vidal A, Salazar R, Martínez Iniesta M, et al. Hepatic carcinoma-associated fibroblasts promote an adaptative response in colorectal cancer cells that inhibit proliferation and apoptosis: nonresistant cells die by nonapoptotic cell death. Neoplasia. 2011;13:931-46 pubmed
Han X, Wu Z, Di J, Pan Y, Zhang H, Du Y, et al. CXCL9 attenuated chemotherapy-induced intestinal mucositis by inhibiting proliferation and reducing apoptosis. Biomed Pharmacother. 2011;65:547-54 pubmed publisher
Tian F, Lu J, Wang L, Li L, Yang J, Li Y, et al. Increased expression of cellular FLICE/caspase-8 inhibitory protein in condyloma acuminatum. Eur J Dermatol. 2011;21:529-33 pubmed publisher
Gupta G, Dhar K, Del Core M, Hunter W, Hatzoudis G, Agrawal D. Suppressor of cytokine signaling-3 and intimal hyperplasia in porcine coronary arteries following coronary intervention. Exp Mol Pathol. 2011;91:346-52 pubmed publisher
Pillich R, Scarsella G, Risuleo G. Regeneration and DNA demethylation do not trigger PDX-1 expression in rat hepatocytes. World J Biol Chem. 2010;1:281-5 pubmed publisher
Sears D, Luong P, Yuan M, Nteliopoulos G, Man Y, Melo J, et al. Functional phosphoproteomic analysis reveals cold-shock domain protein A to be a Bcr-Abl effector-regulating proliferation and transformation in chronic myeloid leukemia. Cell Death Dis. 2010;1:e93 pubmed publisher
Lin W, Rahman N, Lin J, Zhang H, Gou K, Yu W, et al. Molecular mechanisms of bladder outlet obstruction in transgenic male mice overexpressing aromatase (Cyp19a1). Am J Pathol. 2011;178:1233-44 pubmed publisher
Schütz M, Auth T, Gehrt A, Bosen F, Körber I, Strenzke N, et al. The connexin26 S17F mouse mutant represents a model for the human hereditary keratitis-ichthyosis-deafness syndrome. Hum Mol Genet. 2011;20:28-39 pubmed publisher
Wu Z, Han X, Qin S, Zheng Q, Wang Z, Xiang D, et al. Interleukin 1 receptor antagonist reduces lethality and intestinal toxicity of 5-fluorouracil in a mouse mucositis model. Biomed Pharmacother. 2010;64:589-93 pubmed publisher
Hu J, Yan D, Gao J, Xu C, Yuan Y, Zhu R, et al. rhIL-1Ra reduces hepatocellular apoptosis in mice with acetaminophen-induced acute liver failure. Lab Invest. 2010;90:1737-46 pubmed publisher
Matsumoto K, Huang J, Viswakarma N, Bai L, Jia Y, Zhu Y, et al. Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse. Carcinogenesis. 2010;31:318-25 pubmed publisher
Lu X, Liu J, Legerski R. Cyclin E is stabilized in response to replication fork barriers leading to prolonged S phase arrest. J Biol Chem. 2009;284:35325-37 pubmed publisher
Hu C, Wu Y, Wan Y, Wang Q, Song J. Introduction of hIGF-1 gene into bone marrow stromal cells and its effects on the cell's biological behaviors. Cell Transplant. 2008;17:1067-81 pubmed
Yang J, Li Y, Liu Y, Long J, Tian F, Dong J, et al. Expression of antiapoptotic protein c-FLIP is upregulated in psoriasis epidermis. Eur J Dermatol. 2009;19:29-33 pubmed publisher
Sinha S, Cao Y, Dutta S, Wang E, Mukhopadhyay D. VEGF neutralizing antibody increases the therapeutic efficacy of vinorelbine for renal cell carcinoma. J Cell Mol Med. 2010;14:647-58 pubmed publisher
Shen A, Gao S, Ben Z, Wang H, Jia J, Tao T, et al. Identification and potential role of PSD-95 in Schwann cells. Neurol Sci. 2008;29:321-30 pubmed publisher
Qiao L, Xu Y, Liu X, Xie J, Wang J, Du C, et al. PKC promotes proliferation of airway smooth muscle cells by regulating cyclinD1 expression in asthmatic rats. Acta Pharmacol Sin. 2008;29:677-86 pubmed publisher
Pedrana G, Sloboda D, Perez W, Newnham J, Bielli A, Martin G. Effects of pre-natal glucocorticoids on testicular development in sheep. Anat Histol Embryol. 2008;37:352-8 pubmed publisher
Purow B, Sundaresan T, Burdick M, Kefas B, Comeau L, Hawkinson M, et al. Notch-1 regulates transcription of the epidermal growth factor receptor through p53. Carcinogenesis. 2008;29:918-25 pubmed publisher
Souza Rodrígues E, Estanyol J, Friedrich Heineken E, Olmedo E, Vera J, Canela N, et al. Proteomic analysis of p16ink4a-binding proteins. Proteomics. 2007;7:4102-11 pubmed
Keck M, Romero Aleshire M, Cai Q, Hoyer P, Brooks H. Hormonal status affects the progression of STZ-induced diabetes and diabetic renal damage in the VCD mouse model of menopause. Am J Physiol Renal Physiol. 2007;293:F193-9 pubmed
Horton J, Margulies B, Strauss J, Bariteau J, Damron T, Spadaro J, et al. Restoration of growth plate function following radiotherapy is driven by increased proliferative and synthetic activity of expansions of chondrocytic clones. J Orthop Res. 2006;24:1945-56 pubmed
Pestana I, Vazquez Padron R, Aitouche A, Pham S. Nicotinic and PDGF-receptor function are essential for nicotine-stimulated mitogenesis in human vascular smooth muscle cells. J Cell Biochem. 2005;96:986-95 pubmed
Chen H, Liu Y, Zhou X, Luo R. Expression of cellular FLICE/caspase-8 inhibitory protein is associated with malignant potential in endometrial carcinoma. Int J Gynecol Cancer. 2005;15:663-70 pubmed
product information
Catalog Number :
sc-25280
Product Name :
PCNA (F-2) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
F-2
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
PCNA
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA