product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
TH (F-11) Antibody
catalog :
sc-25269
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
F-11
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 37
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; rat; 1:500; loading ...; fig 5c
  • western blot; rat; loading ...; fig 5a
Song S, Jang W, Jang E, Kim O, Kim H, Son T, et al. Striatal miR-183-5p inhibits methamphetamine-induced locomotion by regulating glucocorticoid receptor signaling. Front Pharmacol. 2022;13:997701 pubmed publisher
  • immunohistochemistry - free floating section; mouse; loading ...; fig 2c
  • immunocytochemistry; mouse; loading ...; fig s1b
  • western blot; mouse; loading ...; fig 5a
  • immunohistochemistry - paraffin section; human; loading ...; fig 1d, 1e
  • western blot; human; loading ...; fig 1b
Chen G, Ahn E, Kang S, Xia Y, Liu X, Zhang Z, et al. UNC5C Receptor Proteolytic Cleavage by Active AEP Promotes Dopaminergic Neuronal Degeneration in Parkinson's Disease. Adv Sci (Weinh). 2022;9:e2103396 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 1b
Zhang C, Zhao M, Wang B, Su Z, Guo B, Qin L, et al. The Nrf2-NLRP3-caspase-1 axis mediates the neuroprotective effects of Celastrol in Parkinson's disease. Redox Biol. 2021;47:102134 pubmed publisher
  • immunohistochemistry; mouse; 1:2000; fig 3d
Uchida S, Soya S, Saito Y, Hirano A, Koga K, Tsuda M, et al. A discrete glycinergic neuronal population in the ventromedial medulla that induces muscle atonia during REM sleep and cataplexy in mice. J Neurosci. 2020;: pubmed publisher
  • immunohistochemistry; rat; 1:1000; loading ...; fig 3a
Jung D, Ahn S, Pak M, Lee H, Jung Y, Kim K, et al. Therapeutic effects of anodal transcranial direct current stimulation in a rat model of ADHD. elife. 2020;9: pubmed publisher
  • immunohistochemistry; mouse; loading ...
Niu H, Wang Q, Zhao W, Liu J, Wang D, Muhammad B, et al. IL-1β/IL-1R1 signaling induced by intranasal lipopolysaccharide infusion regulates alpha-Synuclein pathology in the olfactory bulb, substantia nigra and striatum. Brain Pathol. 2020;30:1102-1118 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1a
  • western blot; mouse; loading ...; fig 2a, 8b
Zhang W, Zhou M, Lu W, Gong J, Gao F, Li Y, et al. CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes. Theranostics. 2020;10:3000-3021 pubmed publisher
  • western blot; mouse; loading ...; fig 2a
Hurr C, Simonyan H, Morgan D, Rahmouni K, Young C. Liver sympathetic denervation reverses obesity-induced hepatic steatosis. J Physiol. 2019;597:4565-4580 pubmed publisher
  • immunohistochemistry; mouse; fig 2b
  • western blot; mouse; fig 2c
Zhang Z, Chu S, Wang S, Jiang Y, Gao Y, Yang P, et al. RTP801 is a critical factor in the neurodegeneration process of A53T α-synuclein in a mouse model of Parkinson's disease under chronic restraint stress. Br J Pharmacol. 2018;175:590-605 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:10,000; fig s9d
van Groningen T, Koster J, Valentijn L, Zwijnenburg D, Akogul N, Hasselt N, et al. Neuroblastoma is composed of two super-enhancer-associated differentiation states. Nat Genet. 2017;49:1261-1266 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 5
  • western blot; mouse; loading ...; fig 7a
Fukada M, Nakayama A, Mamiya T, Yao T, Kawaguchi Y. Dopaminergic abnormalities in Hdac6-deficient mice. Neuropharmacology. 2016;110:470-479 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 7
Winiecka Klimek M, Smolarz M, Walczak M, Zieba J, Hulas Bigoszewska K, Kmieciak B, et al. SOX2 and SOX2-MYC Reprogramming Process of Fibroblasts to the Neural Stem Cells Compromised by Senescence. PLoS ONE. 2015;10:e0141688 pubmed publisher
  • western blot; mouse; loading ...; fig 1
Tuon T, Souza P, Santos M, Pereira F, Pedroso G, Luciano T, et al. Physical Training Regulates Mitochondrial Parameters and Neuroinflammatory Mechanisms in an Experimental Model of Parkinson's Disease. Oxid Med Cell Longev. 2015;2015:261809 pubmed publisher
Kang J, Huang G, Ma L, Tong Y, Shahapal A, Chen P, et al. Cell autonomous role of leucine-rich repeat kinase in protection of dopaminergic neuron survival. bioRxiv. 2023;: pubmed publisher
Chen D, Qi Y, Zhang J, Yang Y. Deconstruction of a hypothalamic astrocyte-white adipocyte sympathetic axis that regulates lipolysis in mice. Nat Commun. 2022;13:7536 pubmed publisher
Takahashi A, Durand de Cuttoli R, Flanigan M, Hasegawa E, Tsunematsu T, Aleyasin H, et al. Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice. Nat Commun. 2022;13:4039 pubmed publisher
Wang N, Ji X, Wu Y, Zhou S, Peng H, Wang J, et al. The Different Molecular Code in Generation of Dopaminergic Neurons from Astrocytes and Mesenchymal Stem Cells. Int J Mol Sci. 2021;22: pubmed publisher
Zhang W, Chen H, Ding L, Gong J, Zhang M, Guo W, et al. Trojan Horse Delivery of 4,4'-Dimethoxychalcone for Parkinsonian Neuroprotection. Adv Sci (Weinh). 2021;8:2004555 pubmed publisher
Cascella R, Chen S, Bigi A, Camino J, Xu C, Dobson C, et al. The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells. Nat Commun. 2021;12:1814 pubmed publisher
Lapierre M, Godbersen S, Torres Esteban M, Schad A, Treier M, Ghoshdastider U, et al. MicroRNA-7a2 Regulates Prolactin in Developing Lactotrophs and Prolactinoma Cells. Endocrinology. 2021;162: pubmed publisher
Bengoa Vergniory N, Faggiani E, Ramos Gonzalez P, Kirkiz E, Connor Robson N, Brown L, et al. CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease. Nat Commun. 2020;11:4885 pubmed publisher
Bosi G, Lorenzoni M, Carosi A, Sayyaf Dezfuli B. Mucosal Hallmarks in the Alimentary Canal of Northern Pike Esox lucius (Linnaeus). Animals (Basel). 2020;10: pubmed publisher
Katsurada K, Nandi S, Sharma N, Zheng H, Liu X, Patel K. Does glucagon-like peptide-1 induce diuresis and natriuresis by modulating afferent renal nerve activity?. Am J Physiol Renal Physiol. 2019;317:F1010-F1021 pubmed publisher
Tuesta L, Djekidel M, Chen R, Lu F, Wang W, Sabatini B, et al. In vivo nuclear capture and molecular profiling identifies Gmeb1 as a transcriptional regulator essential for dopamine neuron function. Nat Commun. 2019;10:2508 pubmed publisher
Lim J, Bang Y, Choi J, Han A, Kwon M, Liu K, et al. LRRK2 G2019S Induces Anxiety/Depression-like Behavior before the Onset of Motor Dysfunction with 5-HT1A Receptor Upregulation in Mice. J Neurosci. 2018;38:1611-1621 pubmed publisher
Kodani S, Soya S, Sakurai T. Excitation of GABAergic Neurons in the Bed Nucleus of the Stria Terminalis Triggers Immediate Transition from Non-Rapid Eye Movement Sleep to Wakefulness in Mice. J Neurosci. 2017;37:7164-7176 pubmed publisher
Di X, Yan J, Zhao Y, Chang Y, Zhao B. L-theanine inhibits nicotine-induced dependence via regulation of the nicotine acetylcholine receptor-dopamine reward pathway. Sci China Life Sci. 2012;55:1064-74 pubmed publisher
Park S, Kim E, Koh S, Maeng S, Lee W, Lim J, et al. Dopaminergic differentiation of neural progenitors derived from placental mesenchymal stem cells in the brains of Parkinson's disease model rats and alleviation of asymmetric rotational behavior. Brain Res. 2012;1466:158-66 pubmed publisher
Kim S, Lim J, Bang Y, Gal J, Lee S, Cho Y, et al. Licochalcone E activates Nrf2/antioxidant response element signaling pathway in both neuronal and microglial cells: therapeutic relevance to neurodegenerative disease. J Nutr Biochem. 2012;23:1314-23 pubmed publisher
Esteve Rudd J, Fernández Sánchez L, Lax P, de Juan E, Martín Nieto J, Cuenca N. Rotenone induces degeneration of photoreceptors and impairs the dopaminergic system in the rat retina. Neurobiol Dis. 2011;44:102-15 pubmed publisher
Lu J, Chen S, Zhang X, Ding J, Meng L. The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells. Invest New Drugs. 2011;29:1276-83 pubmed publisher
Wills J, Jones J, Haggerty T, Duka V, Joyce J, Sidhu A. Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementia. Exp Neurol. 2010;225:210-8 pubmed publisher
Alladi P, Mahadevan A, Shankar S, Raju T, Muthane U. Expression of GDNF receptors GFRalpha1 and RET is preserved in substantia nigra pars compacta of aging Asian Indians. J Chem Neuroanat. 2010;40:43-52 pubmed publisher
Rieske P, Golanska E, Zakrzewska M, Piaskowski S, Hulas Bigoszewska K, Wolańczyk M, et al. Arrested neural and advanced mesenchymal differentiation of glioblastoma cells-comparative study with neural progenitors. BMC Cancer. 2009;9:54 pubmed publisher
Michard Q, Commo S, Rocchetti J, El Houari F, Alleaume A, Wakamatsu K, et al. TRP-2 expression protects HEK cells from dopamine- and hydroquinone-induced toxicity. Free Radic Biol Med. 2008;45:1002-10 pubmed publisher
Witusik M, Piaskowski S, Hulas Bigoszewska K, Zakrzewska M, Gresner S, Azizi S, et al. Successful elimination of non-neural cells and unachievable elimination of glial cells by means of commonly used cell culture manipulations during differentiation of GFAP and SOX2 positive neural progenitors (NHA) to neuronal cells. BMC Biotechnol. 2008;8:56 pubmed publisher
Shin N, Jeong H, Kwon J, Heo H, Kwon J, Yun H, et al. LRRK2 regulates synaptic vesicle endocytosis. Exp Cell Res. 2008;314:2055-65 pubmed publisher
product information
Catalog Number :
sc-25269
Product Name :
TH (F-11) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
F-11
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
TH
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA