product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
E2F-1 (KH95) X Antibody
catalog :
sc-251 X
quantity :
200 µg/0.1 ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
KH95
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, other
citations: 23
Published Application/Species/Sample/DilutionReference
  • chromatin immunoprecipitation; human; loading ...; fig 2d
  • immunoprecipitation; human; loading ...; fig 1a
  • immunocytochemistry; human; loading ...; fig 1b
  • western blot; human; loading ...; fig 2a
Goody D, Gupta S, Engelmann D, Spitschak A, Marquardt S, Mikkat S, et al. Drug Repositioning Inferred from E2F1-Coregulator Interactions Studies for the Prevention and Treatment of Metastatic Cancers. Theranostics. 2019;9:1490-1509 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 2c
  • western blot; human; loading ...; fig 2b
Komori H, Goto Y, Kurayoshi K, Ozono E, Iwanaga R, Bradford A, et al. Differential requirement for dimerization partner DP between E2F-dependent activation of tumor suppressor and growth-related genes. Sci Rep. 2018;8:8438 pubmed publisher
  • western blot; mouse; loading ...; fig 1b
Swartz K, Wood S, Murthy T, Ramirez O, Qin G, Pillai M, et al. E2F-2 Promotes Nuclear Condensation and Enucleation of Terminally Differentiated Erythroblasts. Mol Cell Biol. 2017;37: pubmed publisher
  • western blot; human; loading ...; fig 6b
Cao L, Zhang L, Zhao X, Zhang Y. A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells. PLoS ONE. 2016;11:e0161025 pubmed publisher
  • western blot; human; fig 1
Hossain M, Stillman B. Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription. elife. 2016;5: pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 4a
  • western blot; human; loading ...; fig 4b
Wang C, Chen Y, Wang C, Yu J, Chang Y, Yu C. mTOR regulates proteasomal degradation and Dp1/E2F1- mediated transcription of KPNA2 in lung cancer cells. Oncotarget. 2016;7:25432-42 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; human; fig 5
Mahanic C, Budhavarapu V, Graves J, Li G, Lin W. Regulation of E2 promoter binding factor 1 (E2F1) transcriptional activity through a deubiquitinating enzyme, UCH37. J Biol Chem. 2015;290:26508-22 pubmed publisher
  • western blot; mouse; fig 1
Ma Q, Hu Q, Xu R, Zhen X, Wang G. Protease Omi facilitates neurite outgrowth in mouse neuroblastoma N2a cells by cleaving transcription factor E2F1. Acta Pharmacol Sin. 2015;36:966-75 pubmed publisher
  • western blot; human; 1:200; loading ...; fig 3a
Wang Y, Deng O, Feng Z, Du Z, Xiong X, Lai J, et al. RNF126 promotes homologous recombination via regulation of E2F1-mediated BRCA1 expression. Oncogene. 2016;35:1363-72 pubmed publisher
  • western blot; human
Aguilar H, Urruticoechea A, Halonen P, Kiyotani K, Mushiroda T, Barril X, et al. VAV3 mediates resistance to breast cancer endocrine therapy. Breast Cancer Res. 2014;16:R53 pubmed publisher
  • chromatin immunoprecipitation; human
  • immunoprecipitation; human
  • western blot; human
Zhang W, Ji W, Liu X, Ouyang G, Xiao W. ELL inhibits E2F1 transcriptional activity by enhancing E2F1 deacetylation via recruitment of histone deacetylase 1. Mol Cell Biol. 2014;34:765-75 pubmed publisher
Ankers J, Awais R, Jones N, Boyd J, Ryan S, Adamson A, et al. Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation. elife. 2016;5: pubmed publisher
Wang B, Ma A, Zhang L, Jin W, Qian Y, Xu G, et al. POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation. Nat Commun. 2015;6:8704 pubmed publisher
Wang Y, Alla V, Goody D, Gupta S, Spitschak A, Wolkenhauer O, et al. Epigenetic factor EPC1 is a master regulator of DNA damage response by interacting with E2F1 to silence death and activate metastasis-related gene signatures. Nucleic Acids Res. 2016;44:117-33 pubmed publisher
Chi S, Seo Y, Park Y, Yoon S, Park C, Kim Y, et al. REGNET: mining context-specific human transcription networks using composite genomic information. BMC Genomics. 2014;15:450 pubmed publisher
Kagawa Y, Matsumoto S, Kamioka Y, Mimori K, Naito Y, Ishii T, et al. Cell cycle-dependent Rho GTPase activity dynamically regulates cancer cell motility and invasion in vivo. PLoS ONE. 2013;8:e83629 pubmed publisher
McGirt L, Adams C, Baerenwald D, Zwerner J, Zic J, Eischen C. miR-223 regulates cell growth and targets proto-oncogenes in mycosis fungoides/cutaneous T-cell lymphoma. J Invest Dermatol. 2014;134:1101-1107 pubmed publisher
Zalmas L, Coutts A, Helleday T, La Thangue N. E2F-7 couples DNA damage-dependent transcription with the DNA repair process. Cell Cycle. 2013;12:3037-51 pubmed publisher
Docquier A, Augereau P, Lapierre M, Harmand P, Badia E, Annicotte J, et al. The RIP140 gene is a transcriptional target of E2F1. PLoS ONE. 2012;7:e35839 pubmed publisher
Hayami S, Yoshimatsu M, Veerakumarasivam A, Unoki M, Iwai Y, Tsunoda T, et al. Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway. Mol Cancer. 2010;9:59 pubmed publisher
Nonne N, Ameyar Zazoua M, Souidi M, Harel Bellan A. Tandem affinity purification of miRNA target mRNAs (TAP-Tar). Nucleic Acids Res. 2010;38:e20 pubmed publisher
Halaban R, Cheng E, Smicun Y, Germino J. Deregulated E2F transcriptional activity in autonomously growing melanoma cells. J Exp Med. 2000;191:1005-16 pubmed
product information
Catalog Number :
sc-251 X
Product Name :
E2F-1 (KH95) X Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
KH95
Isotype :
IgG2a
Size :
200 µg/0.1 ml
List Price :
316 USD
Immunogen :
E2F-1
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA