product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Cdk5 (DC 17) Antibody
catalog :
sc-249
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DC 17
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, other, western blot knockout validation
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; 1:1000; loading ...; fig 1f
Sang Y, Li Y, Zhang Y, Alvarez A, Yu B, Zhang W, et al. CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity. Nat Commun. 2019;10:4013 pubmed publisher
  • western blot; human; 1:5000; loading ...; fig s1c
  • western blot knockout validation; mouse; 1:5000; loading ...; fig 1c
Huang H, Lin X, Liang Z, Zhao T, Du S, Loy M, et al. Cdk5-dependent phosphorylation of liprin?1 mediates neuronal activity-dependent synapse development. Proc Natl Acad Sci U S A. 2017;114:E6992-E7001 pubmed publisher
  • western blot; human; 1:2000; fig 4
Xiang J, Guo S, Jiang S, Xu Y, Li J, Li L, et al. Silencing of Long Non-Coding RNA MALAT1 Promotes Apoptosis of Glioma Cells. J Korean Med Sci. 2016;31:688-94 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; rat; fig 3
  • western blot; mouse; 1:1000; fig 2
Zhang P, Fu W, Fu A, Ip N. S-nitrosylation-dependent proteasomal degradation restrains Cdk5 activity to regulate hippocampal synaptic strength. Nat Commun. 2015;6:8665 pubmed publisher
  • immunoprecipitation; human; fig 1
Jirawatnotai S, Sharma S, Michowski W, Suktitipat B, Geng Y, Quackenbush J, et al. The cyclin D1-CDK4 oncogenic interactome enables identification of potential novel oncogenes and clinical prognosis. Cell Cycle. 2014;13:2889-900 pubmed publisher
  • western blot; human; 1:2000; fig 7c
Ye T, Ip J, Fu A, Ip N. Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex. Nat Commun. 2014;5:4826 pubmed publisher
  • western blot; mouse
Tang J, Ip J, Ye T, Ng Y, Yung W, Wu Z, et al. Cdk5-dependent Mst3 phosphorylation and activity regulate neuronal migration through RhoA inhibition. J Neurosci. 2014;34:7425-36 pubmed publisher
di Meco A, Li J, Barrero C, Merali S, Pratico D. Elevated levels of brain homocysteine directly modulate the pathological phenotype of a mouse model of tauopathy. Mol Psychiatry. 2018;: pubmed publisher
Holmgren A, Bouhy D, de Winter V, Asselbergh B, Timmermans J, Irobi J, et al. Charcot-Marie-Tooth causing HSPB1 mutations increase Cdk5-mediated phosphorylation of neurofilaments. Acta Neuropathol. 2013;126:93-108 pubmed publisher
Arpitha P, Gao C, Tripathi B, Saravanamuthu S, Zelenka P. Cyclin-dependent kinase 5 promotes the stability of corneal epithelial cell junctions. Mol Vis. 2013;19:319-32 pubmed
Ohara Imaizumi M, Yoshida M, Aoyagi K, Saito T, Okamura T, Takenaka H, et al. Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis. PLoS ONE. 2010;5:e15553 pubmed publisher
Dong H, Lin W, Wu J, Chen T. Flavonoids activate pregnane x receptor-mediated CYP3A4 gene expression by inhibiting cyclin-dependent kinases in HepG2 liver carcinoma cells. BMC Biochem. 2010;11:23 pubmed publisher
product information
Product Name :
Cdk5 (DC 17) Antibody
Gene Name :
CDK5
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-249
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Cdk5
reactive species  :
m, r, h
Application :
WB, IP, IF, ELISA
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA