Published Application/Species/Sample/Dilution | Reference |
---|
- western blot knockout validation; mouse; 1:1000; loading ...; fig 1c
| Langhans M, Gao J, Tang Y, Wang B, Alexander P, Tuan R. Wdpcp regulates cellular proliferation and differentiation in the developing limb via hedgehog signaling. BMC Dev Biol. 2021;21:10 pubmed publisher
|
- western blot; human; 1:500; loading ...
| Lou X, Ning J, Liu W, Li K, Qian B, Xu D, et al. YTHDF1 Promotes Cyclin B1 Translation through m6A Modulation and Contributes to the Poor Prognosis of Lung Adenocarcinoma with KRAS/TP53 Co-Mutation. Cells. 2021;10: pubmed publisher
|
- western blot; human; loading ...; fig 5e
| Fischietti M, Eckerdt F, Blyth G, Arslan A, Mati W, Oku C, et al. Schlafen 5 as a novel therapeutic target in pancreatic ductal adenocarcinoma. Oncogene. 2021;40:3273-3286 pubmed publisher
|
| Xue J, Zhao Y, Aronowitz J, Mai T, Vides A, Qeriqi B, et al. Rapid non-uniform adaptation to conformation-specific KRAS(G12C) inhibition. Nature. 2020;577:421-425 pubmed publisher
|
- western blot; human; loading ...; fig 3c
| Singh V, Khalil M, De Benedetti A. The TLK1/Nek1 axis contributes to mitochondrial integrity and apoptosis prevention via phosphorylation of VDAC1. Cell Cycle. 2020;19:363-375 pubmed publisher
|
- immunoprecipitation; human; loading ...; fig 4a
- immunocytochemistry; human; loading ...; fig 4b
- immunohistochemistry; human; loading ...; fig 1g, 1h
- western blot; human; loading ...; fig 3a
| Kwan S, Au Yeung C, Yeung T, Rynne Vidal A, Wong K, Risinger J, et al. Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) Promotes Uterine Serous Cancer Cell Proliferation and Cell Cycle Progression. Cancers (Basel). 2020;12: pubmed publisher
|
- western blot; human; 1:800; loading ...; fig 4
| Horton A, Brooker J, Streitfeld W, Flessa M, Pillai B, Simpson R, et al. Nkx2-5 Second Heart Field Target Gene Ccdc117 Regulates DNA Metabolism and Proliferation. Sci Rep. 2019;9:1738 pubmed publisher
|
- western blot; human; 1:1000; loading ...; fig 5a
| Lei T, Zhang P, Zhang X, Xiao X, Zhang J, Qiu T, et al. Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation. Nat Commun. 2018;9:1876 pubmed publisher
|
- immunocytochemistry; human; 1:25; loading ...; fig 5a
| Ruppert J, Samejima K, Platani M, Molina O, Kimura H, Jeyaprakash A, et al. HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry. EMBO J. 2018;37: pubmed publisher
|
- western blot; human; loading ...; fig 1a
| Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira N, et al. Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance. Nature. 2018;553:91-95 pubmed publisher
|
- western blot; human; 1:300; loading ...; fig s4j
| Huang C, Wu S, Ji H, Yan X, Xie Y, Murai S, et al. Identification of XBP1-u as a novel regulator of the MDM2/p53 axis using an shRNA library. Sci Adv. 2017;3:e1701383 pubmed publisher
|
- immunoprecipitation; human; loading ...; fig 2c
- western blot; human; loading ...; fig 2a
| Giono L, Resnick Silverman L, Carvajal L, St Clair S, Manfredi J. Mdm2 promotes Cdc25C protein degradation and delays cell cycle progression through the G2/M phase. Oncogene. 2017;36:6762-6773 pubmed publisher
|
- western blot; human; 1:2000; loading ...; fig s6d
| Takaki T, Montagner M, Serres M, Le Berre M, Russell M, Collinson L, et al. Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability. Nat Commun. 2017;8:16013 pubmed publisher
|
- western blot; human; 1:1000; loading ...; fig 2d
| Li Z, Li D, Choi E, Lapidus R, Zhang L, Huang S, et al. Silencing of solute carrier family 13 member 5 disrupts energy homeostasis and inhibits proliferation of human hepatocarcinoma cells. J Biol Chem. 2017;292:13890-13901 pubmed publisher
|
- western blot; human; loading ...; fig 2e
| Paul A, Wang B. RNF8- and Ube2S-Dependent Ubiquitin Lysine 11-Linkage Modification in Response to DNA Damage. Mol Cell. 2017;66:458-472.e5 pubmed publisher
|
- western blot; human; 1:500; loading ...; fig 3c
| Sandén E, Dyberg C, Krona C, Gallo Oller G, Olsen T, Enríquez Pérez J, et al. Establishment and characterization of an orthotopic patient-derived Group 3 medulloblastoma model for preclinical drug evaluation. Sci Rep. 2017;7:46366 pubmed publisher
|
- western blot; human; 1:500; loading ...; fig 6e; S6i
| Vallejo A, Perurena N, Guruceaga E, Mazur P, Martínez Canarias S, Zandueta C, et al. An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer. Nat Commun. 2017;8:14294 pubmed publisher
|
- western blot; human; fig 2a
| Shin S, Song J, Hwang B, Noh D, Park S, Kim W, et al. HSPA6 augments garlic extract-induced inhibition of proliferation, migration, and invasion of bladder cancer EJ cells; Implication for cell cycle dysregulation, signaling pathway alteration, and transcription factor-associated MMP-9 regulation. PLoS ONE. 2017;12:e0171860 pubmed publisher
|
- immunocytochemistry; human; 1:400; loading ...; fig 4b
| Bot C, Pfeiffer A, Giordano F, Manjeera D, Dantuma N, Ström L. Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage. J Cell Sci. 2017;130:1134-1146 pubmed publisher
|
- western blot; mouse; fig 2a
| Tormos A, Rius Pérez S, Jorques M, Rada P, Ramírez L, Valverde A, et al. p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging. PLoS ONE. 2017;12:e0171738 pubmed publisher
|
- immunocytochemistry; human; loading ...; fig ms1
| Li J, Dang N, Wood D, Huang J. The kinetochore-dependent and -independent formation of the CDC20-MAD2 complex and its functions in HeLa cells. Sci Rep. 2017;7:41072 pubmed publisher
|
- immunocytochemistry; human; loading ...; fig 5c
| Huang Z, Zhou X, He Y, Ke X, Wen Y, Zou F, et al. Hyperthermia enhances 17-DMAG efficacy in hepatocellular carcinoma cells with aggravated DNA damage and impaired G2/M transition. Sci Rep. 2016;6:38072 pubmed publisher
|
- immunocytochemistry; rat; fig 6a
| Dubey A, Copeland P. The Selenocysteine-Specific Elongation Factor Contains Unique Sequences That Are Required for Both Nuclear Export and Selenocysteine Incorporation. PLoS ONE. 2016;11:e0165642 pubmed publisher
|
- western blot; human; loading ...; fig 2e
| Matsuura K, Huang N, Cocce K, Zhang L, Kornbluth S. Downregulation of the proapoptotic protein MOAP-1 by the UBR5 ubiquitin ligase and its role in ovarian cancer resistance to cisplatin. Oncogene. 2017;36:1698-1706 pubmed publisher
|
- western blot; human; 1:500; loading ...; fig 2c
| Wei R, Lin S, Wu W, Chen L, Li C, Chen H, et al. A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Toxicol Appl Pharmacol. 2016;311:88-98 pubmed publisher
|
- immunocytochemistry; human; 1:500; fig 1
- western blot; human; 1:500; fig 3
| Feringa F, Krenning L, Koch A, van den Berg J, van den Broek B, Jalink K, et al. Hypersensitivity to DNA damage in antephase as a safeguard for genome stability. Nat Commun. 2016;7:12618 pubmed publisher
|
- western blot; human; fig 2b
| Park Y, Nam H, Do M, Lee J. The p90 ribosomal S6 kinase 2 specifically affects mitotic progression by regulating the basal level, distribution and stability of mitotic spindles. Exp Mol Med. 2016;48:e250 pubmed publisher
|
- western blot; human; loading ...; fig s2a
| Zhang X, Ling Y, Guo Y, Bai Y, Shi X, Gong F, et al. Mps1 kinase regulates tumor cell viability via its novel role in mitochondria. Cell Death Dis. 2016;7:e2292 pubmed publisher
|
- western blot; human; loading ...; fig 2j
| Gholkar A, Cheung K, Williams K, Lo Y, Hamideh S, Nnebe C, et al. Fatostatin Inhibits Cancer Cell Proliferation by Affecting Mitotic Microtubule Spindle Assembly and Cell Division. J Biol Chem. 2016;291:17001-8 pubmed publisher
|
- western blot; mouse; 1:200; loading ...; fig 2c
| Rozo M, Li L, Fan C. Targeting ?1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice. Nat Med. 2016;22:889-96 pubmed publisher
|
- western blot; human; loading ...; fig 1c
| Chung H, Park J, Lee N, Kim H, Jang C. Phosphorylation of Astrin Regulates Its Kinetochore Function. J Biol Chem. 2016;291:17579-92 pubmed publisher
|
- western blot; human; 1:200; fig 3
| Ercilla A, Llopis A, Feu S, Aranda S, Ernfors P, Freire R, et al. New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress. Nucleic Acids Res. 2016;44:4745-62 pubmed publisher
|
- western blot; human; 1:1000; fig 2
| Liu T, Fang Z, Wang G, Shi M, Wang X, Jiang K, et al. Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells. Oncol Lett. 2016;11:182-188 pubmed
|
- flow cytometry; human; fig 2
- western blot; human; fig 1
| Hasvold G, Lund Andersen C, Lando M, Patzke S, Hauge S, Suo Z, et al. Hypoxia-induced alterations of G2 checkpoint regulators. Mol Oncol. 2016;10:764-73 pubmed publisher
|
- western blot; human; 1:1000; fig 5c
| O Connor A, Maffini S, Rainey M, Kaczmarczyk A, Gaboriau D, Musacchio A, et al. Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint. Biol Open. 2015;5:11-9 pubmed publisher
|
- western blot; human; 1:1000; fig s6
| Lyu L, Whitcomb E, Jiang S, Chang M, Gu Y, Duncan M, et al. Unfolded-protein response-associated stabilization of p27(Cdkn1b) interferes with lens fiber cell denucleation, leading to cataract. FASEB J. 2016;30:1087-95 pubmed publisher
|
- western blot; human; fig 3
| Lohberger B, Leithner A, Stuendl N, Kaltenegger H, Kullich W, Steinecker Frohnwieser B. Diacerein retards cell growth of chondrosarcoma cells at the G2/M cell cycle checkpoint via cyclin B1/CDK1 and CDK2 downregulation. BMC Cancer. 2015;15:891 pubmed publisher
|
- western blot; human; fig 1
| Fuchs M, Luthold C, Guilbert S, Varlet A, Lambert H, Jetté A, et al. A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis. PLoS Genet. 2015;11:e1005582 pubmed publisher
|
- western blot; human; 1:1000; fig s3
| Lauková J, KozubÃk A, Hofmanová J, Nekvindová J, Sova P, Moyer M, et al. Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells. PLoS ONE. 2015;10:e0141020 pubmed publisher
|
- western blot; mouse; fig 5c
| Gao L, Tang H, He H, Liu J, Mao J, Ji H, et al. Glycyrrhizic acid alleviates bleomycin-induced pulmonary fibrosis in rats. Front Pharmacol. 2015;6:215 pubmed publisher
|
- immunocytochemistry; human; fig 1
- western blot; human; fig s2
| Voets E, Marsman J, Demmers J, Beijersbergen R, Wolthuis R. The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1. Sci Rep. 2015;5:14798 pubmed publisher
|
- western blot; human; 1:500; loading ...; fig 7d
| Maleszewska M, Vanchin B, Harmsen M, Krenning G. The decrease in histone methyltransferase EZH2 in response to fluid shear stress alters endothelial gene expression and promotes quiescence. Angiogenesis. 2016;19:9-24 pubmed publisher
|
- western blot; human; 1:500
| Seo M, Jang W, Rhee K. Integrity of the Pericentriolar Material Is Essential for Maintaining Centriole Association during M Phase. PLoS ONE. 2015;10:e0138905 pubmed publisher
|
- western blot; human; fig 2
| Bailey M, Singh T, Mero P, Moffat J, Hieter P. Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint. Genetics. 2015;201:885-95 pubmed publisher
|
- western blot; human; fig 5
| Kruiswijk F, Hasenfuss S, Sivapatham R, Baar M, Putavet D, Naipal K, et al. Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signaling. Oncogene. 2016;35:2166-77 pubmed publisher
|
- western blot; human; fig 4
| Wu C, Huang K, Yang T, Li Y, Wen C, Hsu S, et al. The Topoisomerase 1 Inhibitor Austrobailignan-1 Isolated from Koelreuteria henryi Induces a G2/M-Phase Arrest and Cell Death Independently of p53 in Non-Small Cell Lung Cancer Cells. PLoS ONE. 2015;10:e0132052 pubmed publisher
|
- immunocytochemistry; human; fig 3b
- western blot; human; fig 3a
| Liu R, Fan M, Candas D, Qin L, Zhang X, Eldridge A, et al. CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance. Mol Cancer Ther. 2015;14:2090-102 pubmed publisher
|
- western blot; human; 1:200; fig 3
| Moiseeva O, Lessard F, Acevedo Aquino M, Vernier M, Tsantrizos Y, Ferbeyre G. Mutant lamin A links prophase to a p53 independent senescence program. Cell Cycle. 2015;14:2408-21 pubmed publisher
|
- western blot; human; 1:500; fig 1e
| Li C, Wu W, Wu W, Liao Y, Chen L, Huang C, et al. The cAMP responsive element binding protein 1 transactivates epithelial membrane protein 2, a potential tumor suppressor in the urinary bladder urothelial carcinoma. Oncotarget. 2015;6:9220-39 pubmed
|
- immunoprecipitation; human
- western blot; human
| Voets E, Wolthuis R. MASTL promotes cyclin B1 destruction by enforcing Cdc20-independent binding of cyclin B1 to the APC/C. Biol Open. 2015;4:484-95 pubmed publisher
|
- western blot; human; 1:1000
| Masuda K, Chiyoda T, Sugiyama N, Segura Cabrera A, Kabe Y, Ueki A, et al. LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C. PLoS ONE. 2015;10:e0118662 pubmed publisher
|
- western blot; human; fig 3
| Jeong H, Gil N, Lee H, Cho S, Kim K, Chun K, et al. Timely Degradation of Wip1 Phosphatase by APC/C Activator Protein Cdh1 is Necessary for Normal Mitotic Progression. J Cell Biochem. 2015;116:1602-12 pubmed publisher
|
- western blot; human; 1:500
| Hamdi A, Lesnard A, Suzanne P, Robert T, Miteva M, Pellerano M, et al. Tampering with cell division by using small-molecule inhibitors of CDK-CKS protein interactions. Chembiochem. 2015;16:432-9 pubmed publisher
|
| Rizkallah R, Batsomboon P, Dudley G, Hurt M. Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins. Oncotarget. 2015;6:1446-61 pubmed
|
- western blot; human; 1:200; fig 8
| Pérès E, Gérault A, Valable S, Roussel S, Toutain J, Divoux D, et al. Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe. Oncotarget. 2015;6:2101-19 pubmed
|
- western blot; rat; 1:1000; fig 9
| Pino M, Verstraeten S. Tl(I) and Tl(III) alter the expression of EGF-dependent signals and cyclins required for pheochromocytoma (PC12) cell-cycle resumption and progression. J Appl Toxicol. 2015;35:952-69 pubmed publisher
|
| Xue L, Furusawa Y, Okayasu R, Miura M, Cui X, Liu C, et al. The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function. DNA Repair (Amst). 2015;25:72-83 pubmed publisher
|
- immunocytochemistry; human; 1:100
| Brownlow N, Pike T, Zicha D, Collinson L, Parker P. Mitotic catenation is monitored and resolved by a PKCε-regulated pathway. Nat Commun. 2014;5:5685 pubmed publisher
|
| Eifler M, Uecker R, Weisbach H, Bogdanow B, Richter E, König L, et al. PUL21a-Cyclin A2 interaction is required to protect human cytomegalovirus-infected cells from the deleterious consequences of mitotic entry. PLoS Pathog. 2014;10:e1004514 pubmed publisher
|
- western blot; human; loading ...; fig 3b
| Li Y, Kim B, Cho S, Bang M, Kim S, Park D. 6,7-di-O-acetylsinococuline (FK-3000) induces G2/M phase arrest in breast carcinomas through p38 MAPK phosphorylation and CDC25B dephosphorylation. Int J Oncol. 2015;46:578-86 pubmed publisher
|
| Ohoka N, Nagai K, Hattori T, Okuhira K, Shibata N, Cho N, et al. Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin-proteasome pathway. Cell Death Dis. 2014;5:e1513 pubmed publisher
|
- western blot; human; 1:2000; loading ...; fig 2d
| Greve K, Lindgreen J, Terp M, Pedersen C, Schmidt S, Mollenhauer J, et al. Ectopic expression of cancer/testis antigen SSX2 induces DNA damage and promotes genomic instability. Mol Oncol. 2015;9:437-49 pubmed publisher
|
- immunocytochemistry; human
- western blot; human
| van der Lelij P, Stocsits R, Ladurner R, Petzold G, Kreidl E, Koch B, et al. SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs. EMBO J. 2014;33:2643-58 pubmed publisher
|
- western blot; human; 1:1000; fig 5a
| Shandilya J, Toska E, Richard D, Medler K, Roberts S. WT1 interacts with MAD2 and regulates mitotic checkpoint function. Nat Commun. 2014;5:4903 pubmed publisher
|
| Izumi H, Kaneko Y. Trim32 facilitates degradation of MYCN on spindle poles and induces asymmetric cell division in human neuroblastoma cells. Cancer Res. 2014;74:5620-30 pubmed publisher
|
- western blot; mouse; 1:1000
| Jiao G, Lian H, Gao Y, Sun M, Gong S, Zheng L, et al. Carrying-over effects of GVBD blocking on post-blocking meiotic progression of oocytes: species difference and the signaling pathway leading to MPF activation. PLoS ONE. 2014;9:e103838 pubmed publisher
|
- western blot; human; fig 6
| Otani K, Dong Y, Li X, Lu J, Zhang N, Xu L, et al. Odd-skipped related 1 is a novel tumour suppressor gene and a potential prognostic biomarker in gastric cancer. J Pathol. 2014;234:302-15 pubmed publisher
|
| Hu K, Liao D, Wu W, Han A, Shi H, Wang F, et al. Targeting the anaphase-promoting complex/cyclosome (APC/C)- bromodomain containing 7 (BRD7) pathway for human osteosarcoma. Oncotarget. 2014;5:3088-100 pubmed
|
- western blot; human; 1:1000
| Kuijt T, Omerzu M, Saurin A, Kops G. Conditional targeting of MAD1 to kinetochores is sufficient to reactivate the spindle assembly checkpoint in metaphase. Chromosoma. 2014;123:471-80 pubmed publisher
|
- western blot; human; 1:1000; fig 1
| Kitagawa M, Fung S, Hameed U, Goto H, Inagaki M, Lee S. Cdk1 coordinates timely activation of MKlp2 kinesin with relocation of the chromosome passenger complex for cytokinesis. Cell Rep. 2014;7:166-79 pubmed publisher
|
- immunohistochemistry; mouse; 1:100
| Hu J, Lu J, Lian G, Zhang J, Hecht J, Sheen V. Filamin B regulates chondrocyte proliferation and differentiation through Cdk1 signaling. PLoS ONE. 2014;9:e89352 pubmed publisher
|
| Matthess Y, Raab M, Knecht R, Becker S, Strebhardt K. Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis. Mol Oncol. 2014;8:596-608 pubmed publisher
|
- western blot; human; fig 2
| Kim S, Park E, Joo H, Shen Y, Hong S, Kim C, et al. RRM1 maintains centrosomal integrity via CHK1 and CDK1 signaling during replication stress. Cancer Lett. 2014;346:249-56 pubmed publisher
|
- western blot; human; fig 2
| Xu Q, Zhang Y, Xiong X, Huang Y, Salisbury J, Hu J, et al. PIPKI? targets to the centrosome and restrains centriole duplication. J Cell Sci. 2014;127:1293-305 pubmed publisher
|
- western blot; human; 1:1000; fig 8
| Myatt S, Kongsema M, Man C, Kelly D, Gomes A, Khongkow P, et al. SUMOylation inhibits FOXM1 activity and delays mitotic transition. Oncogene. 2014;33:4316-29 pubmed publisher
|
- western blot; human; fig 7
| Liu X, Xiao W, Wang X, Li Y, Han J, Li Y. The p38-interacting protein (p38IP) regulates G2/M progression by promoting ?-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5. J Biol Chem. 2013;288:36648-61 pubmed publisher
|
| Maier B, Kirsch M, Anderhub S, Zentgraf H, Krämer A. The novel actin/focal adhesion-associated protein MISP is involved in mitotic spindle positioning in human cells. Cell Cycle. 2013;12:1457-71 pubmed publisher
|
| Gao D, Inuzuka H, Tseng A, Chin R, Toker A, Wei W. Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. Nat Cell Biol. 2009;11:397-408 pubmed publisher
|
| Bengoechea Alonso M, Punga T, Ericsson J. Hyperphosphorylation regulates the activity of SREBP1 during mitosis. Proc Natl Acad Sci U S A. 2005;102:11681-6 pubmed
|
- immunoprecipitation; human
- western blot; human
| Pappa A, Brown D, Koutalos Y, DeGregori J, White C, Vasiliou V. Human aldehyde dehydrogenase 3A1 inhibits proliferation and promotes survival of human corneal epithelial cells. J Biol Chem. 2005;280:27998-8006 pubmed
|
| Morgan E, Patterson M, Ryder E, Lee S, Wasson C, Harper K, et al. MicroRNA-18a targeting of the STK4/MST1 tumour suppressor is necessary for transformation in HPV positive cervical cancer. PLoS Pathog. 2020;16:e1008624 pubmed publisher
|
| Bobkov G, Huang A, van den Berg S, Mitra S, Anselm E, Lazou V, et al. Spt6 is a maintenance factor for centromeric CENP-A. Nat Commun. 2020;11:2919 pubmed publisher
|
| Odle R, Walker S, Oxley D, Kidger A, Balmanno K, Gilley R, et al. An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis. Mol Cell. 2019;: pubmed publisher
|
| Stauffer S, Zeng Y, Santos M, Zhou J, Chen Y, Dong J. Cyclin-dependent kinase 1-mediated AMPK phosphorylation regulates chromosome alignment and mitotic progression. J Cell Sci. 2019;132: pubmed publisher
|
| Thangaraj K, Balasubramanian B, Park S, Natesan K, Liu W, Manju V. Orientin Induces G0/G1 Cell Cycle Arrest and Mitochondria Mediated Intrinsic Apoptosis in Human Colorectal Carcinoma HT29 Cells. Biomolecules. 2019;9: pubmed publisher
|
| Roman M, Lopez I, Guruceaga E, Baraibar I, Ecay M, Collantes M, et al. Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network. Cancer Res. 2019;79:625-638 pubmed publisher
|
| Kim S, Jin H, Seo H, Lee H, Lee Y. Regulating BRCA1 protein stability by cathepsin S-mediated ubiquitin degradation. Cell Death Differ. 2019;26:812-825 pubmed publisher
|
| Zhou Y, Chu L, Wang Q, Dai W, Zhang X, Chen J, et al. CD59 is a potential biomarker of esophageal squamous cell carcinoma radioresistance by affecting DNA repair. Cell Death Dis. 2018;9:887 pubmed publisher
|
| Hayashi Y, Fujimura A, Kato K, Udagawa R, Hirota T, Kimura K. Nucleolar integrity during interphase supports faithful Cdk1 activation and mitotic entry. Sci Adv. 2018;4:eaap7777 pubmed publisher
|
| Noguchi A, Adachi S, Yokota N, Hatta T, Natsume T, Kawahara H. ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest. Biol Open. 2018;7: pubmed publisher
|
| Misiak M, Heldt M, Szeligowska M, Mazzini S, Scaglioni L, Grabe G, et al. Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7. Oncotarget. 2017;8:105137-105154 pubmed publisher
|
| Zhuge W, Chen R, Vladimir K, Dong X, Zia K, Sun X, et al. Costunolide specifically binds and inhibits thioredoxin reductase 1 to induce apoptosis in colon cancer. Cancer Lett. 2018;412:46-58 pubmed publisher
|
| Iwahori S, Kalejta R. Phosphorylation of transcriptional regulators in the retinoblastoma protein pathway by UL97, the viral cyclin-dependent kinase encoded by human cytomegalovirus. Virology. 2017;512:95-103 pubmed publisher
|
| Nechemia Arbely Y, Fachinetti D, Miga K, Sekulic N, Soni G, Kim D, et al. Human centromeric CENP-A chromatin is a homotypic, octameric nucleosome at all cell cycle points. J Cell Biol. 2017;216:607-621 pubmed publisher
|
| Zhang T, Zhou Y, Li L, Wang Z, Shen W, Schatten H, et al. CenpH regulates meiotic G2/M transition by modulating the APC/CCdh1-cyclin B1 pathway in oocytes. Development. 2017;144:305-312 pubmed publisher
|
| Dawar S, Lim Y, Puccini J, White M, Thomas P, Bouchier Hayes L, et al. Caspase-2-mediated cell death is required for deleting aneuploid cells. Oncogene. 2017;36:2704-2714 pubmed publisher
|
| Uematsu K, Okumura F, Tonogai S, Joo Okumura A, Alemayehu D, Nishikimi A, et al. ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation. J Cell Biol. 2016;215:95-106 pubmed
|
| Lv C, Zhao G, Sun X, Wang P, Xie N, Luo J, et al. Acetylation of FOXM1 is essential for its transactivation and tumor growth stimulation. Oncotarget. 2016;7:60366-60382 pubmed publisher
|
| Müssnich P, Raverot G, Jaffrain Rea M, Fraggetta F, Wierinckx A, Trouillas J, et al. Downregulation of miR-410 targeting the cyclin B1 gene plays a role in pituitary gonadotroph tumors. Cell Cycle. 2015;14:2590-7 pubmed publisher
|
| Müllers E, Silva Cascales H, Jaiswal H, Saurin A, Lindqvist A. Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase. Cell Cycle. 2014;13:2733-43 pubmed publisher
|
| Eichhorn J, Kothari A, Chambers T. Cyclin B1 overexpression induces cell death independent of mitotic arrest. PLoS ONE. 2014;9:e113283 pubmed publisher
|
| Park S, Yu S, Chai Y, Jang Y. CDK2-dependent phosphorylation of Suv39H1 is involved in control of heterochromatin replication during cell cycle progression. Nucleic Acids Res. 2014;42:6196-207 pubmed publisher
|
| Hardy T, Lee M, Hames R, Prosser S, Cheary D, Samant M, et al. Multisite phosphorylation of C-Nap1 releases it from Cep135 to trigger centrosome disjunction. J Cell Sci. 2014;127:2493-506 pubmed publisher
|
| Kuang Z, Yao Y, Shi Y, Gu Z, Sun Z, Tso J. Winter hibernation and UCHL1-p34cdc2 association in toad oocyte maturation competence. PLoS ONE. 2013;8:e78785 pubmed publisher
|
| van der Horst A, Lens S. Cell division: control of the chromosomal passenger complex in time and space. Chromosoma. 2014;123:25-42 pubmed publisher
|
| Tu W, Li B, Huang B, Wang Y, Liu X, Guan H, et al. ?H2AX foci formation in the absence of DNA damage: mitotic H2AX phosphorylation is mediated by the DNA-PKcs/CHK2 pathway. FEBS Lett. 2013;587:3437-43 pubmed publisher
|
| Tao J, Yan C, Tian X, Liu S, Li Y, Zhang J, et al. CREG promotes the proliferation of human umbilical vein endothelial cells through the ERK/cyclin E signaling pathway. Int J Mol Sci. 2013;14:18437-56 pubmed publisher
|
| Redon S, Zemp I, Lingner J. A three-state model for the regulation of telomerase by TERRA and hnRNPA1. Nucleic Acids Res. 2013;41:9117-28 pubmed publisher
|
| Zineldeen D, Wagih A, Nakanishi M. Cloning and functional characterization of Ptpcd2 as a novel cell cycle related protein tyrosine phosphatase that regulates mitotic exit. Asian Pac J Cancer Prev. 2013;14:3669-76 pubmed
|
| Passaro C, Abagnale A, Libertini S, Volpe M, Botta G, Cella L, et al. Ionizing radiation enhances dl922-947-mediated cell death of anaplastic thyroid carcinoma cells. Endocr Relat Cancer. 2013;20:633-47 pubmed publisher
|
| Esterlechner J, Reichert N, Iltzsche F, Krause M, Finkernagel F, Gaubatz S. LIN9, a subunit of the DREAM complex, regulates mitotic gene expression and proliferation of embryonic stem cells. PLoS ONE. 2013;8:e62882 pubmed publisher
|
| Sakai Y, Fukamachi K, Futakuchi M, Hayashi H, Suzui M. Promotive effects of cell proliferation and chromosomal instability induced by tribbles-related protein 3 in mouse mammary tumor cells. Oncol Rep. 2013;30:64-70 pubmed publisher
|
| Cai Y, Xia Q, Luo R, Huang P, Sun Y, Shi Y, et al. Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo. J Nat Med. 2014;68:53-62 pubmed publisher
|
| Pfaff K, King R. Determinants of human cyclin B1 association with mitotic chromosomes. PLoS ONE. 2013;8:e59169 pubmed publisher
|
| Bodor D, Valente L, Mata J, Black B, Jansen L. Assembly in G1 phase and long-term stability are unique intrinsic features of CENP-A nucleosomes. Mol Biol Cell. 2013;24:923-32 pubmed publisher
|
| Zhang Y, Foreman O, Wigle D, Kosari F, Vasmatzis G, Salisbury J, et al. USP44 regulates centrosome positioning to prevent aneuploidy and suppress tumorigenesis. J Clin Invest. 2012;122:4362-74 pubmed publisher
|
| Uzunova K, Dye B, Schutz H, Ladurner R, Petzold G, Toyoda Y, et al. APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex. Nat Struct Mol Biol. 2012;19:1116-23 pubmed publisher
|
| Fedor Y, Vignard J, Nicolau Travers M, Boutet Robinet E, Watrin C, Salles B, et al. From single-strand breaks to double-strand breaks during S-phase: a new mode of action of the Escherichia coli Cytolethal Distending Toxin. Cell Microbiol. 2013;15:1-15 pubmed publisher
|
| Wang Z, Inuzuka H, Zhong J, Fukushima H, Wan L, Liu P, et al. DNA damage-induced activation of ATM promotes ?-TRCP-mediated Mdm2 ubiquitination and destruction. Oncotarget. 2012;3:1026-35 pubmed
|
| Sakurikar N, Eichhorn J, Chambers T. Cyclin-dependent kinase-1 (Cdk1)/cyclin B1 dictates cell fate after mitotic arrest via phosphoregulation of antiapoptotic Bcl-2 proteins. J Biol Chem. 2012;287:39193-204 pubmed publisher
|
| Kim S, Park H, Kim J, Yoon J, Kim E, Cho C, et al. Anti-leukemic effect of a synthetic compound, (±) trans-dihydronarciclasine (HYU-01) via cell-cycle arrest and apoptosis in acute myeloid leukemia. APMIS. 2012;120:836-45 pubmed publisher
|
| Llopis A, Salvador N, Ercilla A, Guaita Esteruelas S, Barrantes I, Gupta J, et al. The stress-activated protein kinases p38?/? and JNK1/2 cooperate with Chk1 to inhibit mitotic entry upon DNA replication arrest. Cell Cycle. 2012;11:3627-37 pubmed publisher
|
| Beck H, Nähse Kumpf V, Larsen M, O Hanlon K, Patzke S, Holmberg C, et al. Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption. Mol Cell Biol. 2012;32:4226-36 pubmed
|
| Lan R, Lin G, Yin F, Xu J, Zhang X, Wang J, et al. Dissecting the phenotypes of Plk1 inhibition in cancer cells using novel kinase inhibitory chemical CBB2001. Lab Invest. 2012;92:1503-14 pubmed publisher
|
| Manzotti G, Mariani S, Corradini F, Bussolari R, Cesi V, Vergalli J, et al. Expression of p89(c-Mybex9b), an alternatively spliced form of c-Myb, is required for proliferation and survival of p210BCR/ABL-expressing cells. Blood Cancer J. 2012;2:e71 pubmed publisher
|
| Lee K, Rhee K. Separase-dependent cleavage of pericentrin B is necessary and sufficient for centriole disengagement during mitosis. Cell Cycle. 2012;11:2476-85 pubmed publisher
|
| Lian G, Lu J, Hu J, Zhang J, Cross S, Ferland R, et al. Filamin a regulates neural progenitor proliferation and cortical size through Wee1-dependent Cdk1 phosphorylation. J Neurosci. 2012;32:7672-84 pubmed publisher
|
| Llaurado M, Majem B, Castellvi J, Cabrera S, Gil Moreno A, Reventos J, et al. Analysis of gene expression regulated by the ETV5 transcription factor in OV90 ovarian cancer cells identifies FOXM1 overexpression in ovarian cancer. Mol Cancer Res. 2012;10:914-24 pubmed publisher
|
| Rouzeau S, Cordelières F, Buhagiar Labarchède G, Hurbain I, Onclercq Delic R, Gemble S, et al. Bloom's syndrome and PICH helicases cooperate with topoisomerase II? in centromere disjunction before anaphase. PLoS ONE. 2012;7:e33905 pubmed publisher
|
| Logan P, Steiner M, Ponnampalam A, Mitchell M. Cell cycle regulation of human endometrial stromal cells during decidualization. Reprod Sci. 2012;19:883-94 pubmed publisher
|
| Zuryn A, Gagat M, Grzanka A, Gackowska L, Grzanka A. Expression of cyclin B1 after induction of senescence and cell death in non-small cell lung carcinoma A549 cells. Folia Histochem Cytobiol. 2012;50:58-67 pubmed publisher
|
| Down C, Millour J, Lam E, Watson R. Binding of FoxM1 to G2/M gene promoters is dependent upon B-Myb. Biochim Biophys Acta. 2012;1819:855-62 pubmed publisher
|
| Lee S, Park S, Kim W, Moon S. Gleditsia sinensis thorn extract inhibits proliferation and TNF-?-induced MMP-9 expression in vascular smooth muscle cells. Am J Chin Med. 2012;40:373-86 pubmed
|
| Takahashi A, Kikuguchi C, Morita M, Shimodaira T, Tokai Nishizumi N, Yokoyama K, et al. Involvement of CNOT3 in mitotic progression through inhibition of MAD1 expression. Biochem Biophys Res Commun. 2012;419:268-73 pubmed publisher
|
| Zuco V, De Cesare M, Cincinelli R, Nannei R, Pisano C, Zaffaroni N, et al. Synergistic antitumor effects of novel HDAC inhibitors and paclitaxel in vitro and in vivo. PLoS ONE. 2011;6:e29085 pubmed publisher
|
| Kim W, Kim R, Park G, Park J, Kim J. Deficiency of H3K79 histone methyltransferase Dot1-like protein (DOT1L) inhibits cell proliferation. J Biol Chem. 2012;287:5588-99 pubmed publisher
|
| Silva M, Bodor D, Stellfox M, Martins N, Hochegger H, Foltz D, et al. Cdk activity couples epigenetic centromere inheritance to cell cycle progression. Dev Cell. 2012;22:52-63 pubmed publisher
|
| Schlick S, Wood C, Gunnell A, Webb H, Khasnis S, Schepers A, et al. Upregulation of the cell-cycle regulator RGC-32 in Epstein-Barr virus-immortalized cells. PLoS ONE. 2011;6:e28638 pubmed publisher
|
| Tipton A, Tipton M, Yen T, Liu S. Closed MAD2 (C-MAD2) is selectively incorporated into the mitotic checkpoint complex (MCC). Cell Cycle. 2011;10:3740-50 pubmed publisher
|
| Chu R, Terrano D, Chambers T. Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration. Biochem Pharmacol. 2012;83:199-206 pubmed publisher
|
| Xiao D, Dai B, Chen J, Luo Q, Liu X, Lin Q, et al. Loss of macrophage migration inhibitory factor impairs the growth properties of human HeLa cervical cancer cells. Cell Prolif. 2011;44:582-90 pubmed publisher
|
| Kim E, Yoon S, Kim E, Kim Y, Lee H, Kim K, et al. Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation. PLoS ONE. 2011;6:e25870 pubmed publisher
|
| Sasaki T, Li A, Gillespie P, Blow J, Gilbert D. Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity. Nucleus. 2011;2:455-64 pubmed publisher
|
| Acin S, Li Z, Mejía O, Roop D, El Naggar A, Caulin C. Gain-of-function mutant p53 but not p53 deletion promotes head and neck cancer progression in response to oncogenic K-ras. J Pathol. 2011;225:479-89 pubmed publisher
|
| Cheung C, Lin W, Hsu J, Hour T, Yeh T, Ko S, et al. BPR1K653, a novel Aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells. PLoS ONE. 2011;6:e23485 pubmed publisher
|
| Scharadin T, Jiang H, Jans R, Rorke E, Eckert R. TIG3 tumor suppressor-dependent organelle redistribution and apoptosis in skin cancer cells. PLoS ONE. 2011;6:e23230 pubmed publisher
|
| Zhang Y, van Deursen J, Galardy P. Overexpression of ubiquitin specific protease 44 (USP44) induces chromosomal instability and is frequently observed in human T-cell leukemia. PLoS ONE. 2011;6:e23389 pubmed publisher
|
| Lee J, Lee H, Moon B, Song S, Lee M, Shim S, et al. Generation of cancerous neural stem cells forming glial tumor by oncogenic stimulation. Stem Cell Rev. 2012;8:532-45 pubmed publisher
|
| Crombez L, Morris M, Heitz F, Divita G. A non-covalent peptide-based strategy for ex vivo and in vivo oligonucleotide delivery. Methods Mol Biol. 2011;764:59-73 pubmed publisher
|
| Giovinazzi S, Lindsay C, Morozov V, Escobar Cabrera E, Summers M, Han H, et al. Regulation of mitosis and taxane response by Daxx and Rassf1. Oncogene. 2012;31:13-26 pubmed publisher
|
| Korfali N, Srsen V, Waterfall M, Batrakou D, Pekovic V, Hutchison C, et al. A flow cytometry-based screen of nuclear envelope transmembrane proteins identifies NET4/Tmem53 as involved in stress-dependent cell cycle withdrawal. PLoS ONE. 2011;6:e18762 pubmed publisher
|
| Tipton A, Wang K, Link L, Bellizzi J, Huang H, Yen T, et al. BUBR1 and closed MAD2 (C-MAD2) interact directly to assemble a functional mitotic checkpoint complex. J Biol Chem. 2011;286:21173-9 pubmed publisher
|
| Ho C, Hau P, Marxer M, Poon R. The requirement of p53 for maintaining chromosomal stability during tetraploidization. Oncotarget. 2010;1:583-95 pubmed
|
| Hage Sleiman R, Herveau S, Matera E, Laurier J, Dumontet C. Silencing of tubulin binding cofactor C modifies microtubule dynamics and cell cycle distribution and enhances sensitivity to gemcitabine in breast cancer cells. Mol Cancer Ther. 2011;10:303-12 pubmed publisher
|
| Nadalutti C, Viiri K, Kaukinen K, Maki M, Lindfors K. Extracellular transglutaminase 2 has a role in cell adhesion, whereas intracellular transglutaminase 2 is involved in regulation of endothelial cell proliferation and apoptosis. Cell Prolif. 2011;44:49-58 pubmed publisher
|
| Yu R, Hu X, Xu S, Jiang Z, Yang W. Effects of fucoxanthin on proliferation and apoptosis in human gastric adenocarcinoma MGC-803 cells via JAK/STAT signal pathway. Eur J Pharmacol. 2011;657:10-9 pubmed publisher
|
| Kim H, Kim C, Lee J, Jang S, Hwang J, Ro S, et al. CG0006, a novel histone deacetylase inhibitor, induces breast cancer cell death via histone-acetylation and chaperone-disrupting pathways independent of ER status. Breast Cancer Res Treat. 2011;130:365-75 pubmed publisher
|
| Wirt S, Adler A, Gebala V, Weimann J, Schaffer B, Saddic L, et al. G1 arrest and differentiation can occur independently of Rb family function. J Cell Biol. 2010;191:809-25 pubmed publisher
|
| Matthess Y, Raab M, Sanhaji M, Lavrik I, Strebhardt K. Cdk1/cyclin B1 controls Fas-mediated apoptosis by regulating caspase-8 activity. Mol Cell Biol. 2010;30:5726-40 pubmed publisher
|
| Bhattacharya A, Li Y, Wade K, Paonessa J, Fahey J, Zhang Y. Allyl isothiocyanate-rich mustard seed powder inhibits bladder cancer growth and muscle invasion. Carcinogenesis. 2010;31:2105-10 pubmed publisher
|
| Sun T, Yang X, Wang W, Zhang X, Xu Q, Zhu S, et al. Cellular abundance of Mps1 and the role of its carboxyl terminal tail in substrate recruitment. J Biol Chem. 2010;285:38730-9 pubmed publisher
|
| Tovar C, Higgins B, Deo D, Kolinsky K, Liu J, Heimbrook D, et al. Small-molecule inducer of cancer cell polyploidy promotes apoptosis or senescence: Implications for therapy. Cell Cycle. 2010;9:3364-75 pubmed publisher
|
| Eves E, Rosner M. MAP kinase regulation of the mitotic spindle checkpoint. Methods Mol Biol. 2010;661:497-505 pubmed publisher
|
| Marais A, Ji Z, Child E, Krause E, Mann D, Sharrocks A. Cell cycle-dependent regulation of the forkhead transcription factor FOXK2 by CDK·cyclin complexes. J Biol Chem. 2010;285:35728-39 pubmed publisher
|
| Nantajit D, Fan M, Duru N, Wen Y, Reed J, Li J. Cyclin B1/Cdk1 phosphorylation of mitochondrial p53 induces anti-apoptotic response. PLoS ONE. 2010;5:e12341 pubmed publisher
|
| Douglas M, Mishima M. Still entangled: assembly of the central spindle by multiple microtubule modulators. Semin Cell Dev Biol. 2010;21:899-908 pubmed publisher
|
| Schwarze F, Meraner J, Lechner M, Loidl A, Stasyk T, Laich A, et al. Cell cycle-dependent acetylation of Rb2/p130 in NIH3T3 cells. Oncogene. 2010;29:5755-60 pubmed publisher
|
| Lee S, Park K, Ha S, Kim W, Moon S. Gleditsia sinensis thorn extract inhibits human colon cancer cells: the role of ERK1/2, G2/M-phase cell cycle arrest and p53 expression. Phytother Res. 2010;24:1870-6 pubmed publisher
|
| Liu J, Wang X, Cheng F, Liou Y, Deng L. Phosphorylation of mixed lineage leukemia 5 by CDC2 affects its cellular distribution and is required for mitotic entry. J Biol Chem. 2010;285:20904-14 pubmed publisher
|
| Lee J, Kim J, Margolis R, Fotedar R. Substrate degradation by the anaphase promoting complex occurs during mitotic slippage. Cell Cycle. 2010;9:1792-801 pubmed
|
| Hsu F, Lin T, Chen J, Shieh S. p53-Mediated transactivation of LIMK2b links actin dynamics to cell cycle checkpoint control. Oncogene. 2010;29:2864-76 pubmed publisher
|
| van Vugt M, Gardino A, Linding R, Ostheimer G, Reinhardt H, Ong S, et al. A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint. PLoS Biol. 2010;8:e1000287 pubmed publisher
|
| Chandris P, Giannouli C, Panayotou G, Kletsas D. Compromise in mRNA processing machinery in senescent human fibroblasts: implications for a novel potential role of Phospho-ATR (ser428). Biogerontology. 2010;11:421-36 pubmed publisher
|
| Trougakos I, Chondrogianni N, Amarantos I, Blake J, Schwager C, Wirkner U, et al. Genome-wide transcriptome profile of the human osteosarcoma Sa OS and U-2 OS cell lines. Cancer Genet Cytogenet. 2010;196:109-18 pubmed publisher
|
| Balasubramanian S, Adhikary G, Eckert R. The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survival. Carcinogenesis. 2010;31:496-503 pubmed publisher
|
| Yan K, Yao C, Chang H, Lai G, Cheng A, Chuang S. The synergistic anticancer effect of troglitazone combined with aspirin causes cell cycle arrest and apoptosis in human lung cancer cells. Mol Carcinog. 2010;49:235-46 pubmed publisher
|
| Levin V, Panchabhai S, Shen L, Kornblau S, Qiu Y, Baggerly K. Different changes in protein and phosphoprotein levels result from serum starvation of high-grade glioma and adenocarcinoma cell lines. J Proteome Res. 2010;9:179-91 pubmed publisher
|
| Lee S, Moon G, Jung K, Kim W, Moon S. c-Jun N-terminal kinase 1 is required for cordycepin-mediated induction of G2/M cell-cycle arrest via p21WAF1 expression in human colon cancer cells. Food Chem Toxicol. 2010;48:277-83 pubmed publisher
|
| Garnier D, Loyer P, Ribault C, Guguen Guillouzo C, Corlu A. Cyclin-dependent kinase 1 plays a critical role in DNA replication control during rat liver regeneration. Hepatology. 2009;50:1946-56 pubmed publisher
|
| Lee S, Kim S, Choi W, Kim W, Moon S. Cordycepin causes p21WAF1-mediated G2/M cell-cycle arrest by regulating c-Jun N-terminal kinase activation in human bladder cancer cells. Arch Biochem Biophys. 2009;490:103-9 pubmed publisher
|
| Yang X, Li H, Liu X, Deng A, Liu X. Cdc2-mediated phosphorylation of CLIP-170 is essential for its inhibition of centrosome reduplication. J Biol Chem. 2009;284:28775-82 pubmed publisher
|
| Li S, Brignole C, Marcellus R, Thirlwell S, Binda O, McQuoid M, et al. The adenovirus E4orf4 protein induces G2/M arrest and cell death by blocking protein phosphatase 2A activity regulated by the B55 subunit. J Virol. 2009;83:8340-52 pubmed publisher
|
| Crombez L, Morris M, Dufort S, Aldrian Herrada G, Nguyen Q, Mc Master G, et al. Targeting cyclin B1 through peptide-based delivery of siRNA prevents tumour growth. Nucleic Acids Res. 2009;37:4559-69 pubmed publisher
|
| Gao D, Inuzuka H, Korenjak M, Tseng A, Wu T, Wan L, et al. Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways. Mol Biol Cell. 2009;20:3305-16 pubmed publisher
|
| Knight A, Notaridou M, Watson R. A Lin-9 complex is recruited by B-Myb to activate transcription of G2/M genes in undifferentiated embryonal carcinoma cells. Oncogene. 2009;28:1737-47 pubmed publisher
|
| Katsuno Y, Suzuki A, Sugimura K, Okumura K, Zineldeen D, Shimada M, et al. Cyclin A-Cdk1 regulates the origin firing program in mammalian cells. Proc Natl Acad Sci U S A. 2009;106:3184-9 pubmed publisher
|
| Lee J, Kim J, Barbier V, Fotedar A, Fotedar R. DNA damage triggers p21WAF1-dependent Emi1 down-regulation that maintains G2 arrest. Mol Biol Cell. 2009;20:1891-902 pubmed publisher
|
| Li W, Kotoshiba S, Berthet C, Hilton M, Kaldis P. Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G1/S transition. Proc Natl Acad Sci U S A. 2009;106:486-91 pubmed publisher
|
| Yamauchi H, Katayama K, Ueno M, Kanemitsu H, Nam C, Mikami T, et al. Etoposide induces TRP53-dependent apoptosis and TRP53-independent cell cycle arrest in trophoblasts of the developing mouse placenta. Biol Reprod. 2009;80:813-22 pubmed publisher
|
| Sinha S, Cao Y, Dutta S, Wang E, Mukhopadhyay D. VEGF neutralizing antibody increases the therapeutic efficacy of vinorelbine for renal cell carcinoma. J Cell Mol Med. 2010;14:647-58 pubmed publisher
|
| Kim E, Kim J, Choi M, Hong S, Bae Y. Effects of excretory/secretory products from Clonorchis sinensis and the carcinogen dimethylnitrosamine on the proliferation and cell cycle modulation of human epithelial HEK293T cells. Korean J Parasitol. 2008;46:127-32 pubmed publisher
|
| Erenpreisa J, Ivanov A, Wheatley S, Kosmacek E, Ianzini F, Anisimov A, et al. Endopolyploidy in irradiated p53-deficient tumour cell lines: persistence of cell division activity in giant cells expressing Aurora-B kinase. Cell Biol Int. 2008;32:1044-56 pubmed publisher
|
| Zuco V, Zunino F. Cyclic pifithrin-alpha sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis. Neoplasia. 2008;10:587-96 pubmed
|
| Bosque A, Aguiló J, Del Rey M, Paz Artal E, Allende L, Naval J, et al. Cell cycle regulation by FasL and Apo2L/TRAIL in human T-cell blasts. Implications for autoimmune lymphoproliferative syndromes. J Leukoc Biol. 2008;84:488-98 pubmed publisher
|
| Chan D, Yu S, Chiu P, Yao K, Liu V, Cheung A, et al. Over-expression of FOXM1 transcription factor is associated with cervical cancer progression and pathogenesis. J Pathol. 2008;215:245-52 pubmed publisher
|
| Raina K, Rajamanickam S, Deep G, Singh M, Agarwal R, Agarwal C. Chemopreventive effects of oral gallic acid feeding on tumor growth and progression in TRAMP mice. Mol Cancer Ther. 2008;7:1258-67 pubmed publisher
|
| Bolton D, Barnitz R, Sakai K, Lenardo M. 14-3-3 theta binding to cell cycle regulatory factors is enhanced by HIV-1 Vpr. Biol Direct. 2008;3:17 pubmed publisher
|
| Kim M, Lee J, Lee S. Transient suppression of nuclear Cdc2 activity in response to ionizing radiation. Oncol Rep. 2008;19:1323-9 pubmed
|
| Laoukili J, Alvarez M, Meijer L, Stahl M, Mohammed S, Kleij L, et al. Activation of FoxM1 during G2 requires cyclin A/Cdk-dependent relief of autorepression by the FoxM1 N-terminal domain. Mol Cell Biol. 2008;28:3076-87 pubmed publisher
|
| Smith Donald B, Durand L, Roizman B. Role of cellular phosphatase cdc25C in herpes simplex virus 1 replication. J Virol. 2008;82:4527-32 pubmed publisher
|
| Smith Donald B, Roizman B. The interaction of herpes simplex virus 1 regulatory protein ICP22 with the cdc25C phosphatase is enabled in vitro by viral protein kinases US3 and UL13. J Virol. 2008;82:4533-43 pubmed publisher
|
| Hansen C, Bartek J, Jensen S. A functional link between the human cell cycle-regulatory phosphatase Cdc14A and the atypical mitogen-activated kinase Erk3. Cell Cycle. 2008;7:325-34 pubmed
|
| Molestina R, El Guendy N, Sinai A. Infection with Toxoplasma gondii results in dysregulation of the host cell cycle. Cell Microbiol. 2008;10:1153-65 pubmed publisher
|
| Kilbey A, Blyth K, Wotton S, Terry A, Jenkins A, Bell M, et al. Runx2 disruption promotes immortalization and confers resistance to oncogene-induced senescence in primary murine fibroblasts. Cancer Res. 2007;67:11263-71 pubmed
|
| Sasaki T, Katayose Y, Yamamoto K, Mizuma M, Shiraso S, Yabuuchi S, et al. Adenovirus expressing mutant p27kip1 enhanced apoptosis and inhibited the growth of xenografted human breast cancer. Surg Today. 2007;37:1073-82 pubmed
|
| Kim Y, Choi M, Hong S, Bae Y. Proliferative effects of excretory/secretory products from Clonorchis sinensis on the human epithelial cell line HEK293 via regulation of the transcription factor E2F1. Parasitol Res. 2008;102:411-7 pubmed
|
| Kim D, Lee H, Park S, Lee S, Ryoo I, Kim W, et al. Terrein inhibits keratinocyte proliferation via ERK inactivation and G2/M cell cycle arrest. Exp Dermatol. 2008;17:312-7 pubmed
|
| Denicourt C, Saenz C, Datnow B, Cui X, Dowdy S. Relocalized p27Kip1 tumor suppressor functions as a cytoplasmic metastatic oncogene in melanoma. Cancer Res. 2007;67:9238-43 pubmed
|
| Kamasani U, DuHadaway J, Alberts A, Prendergast G. mDia function is critical for the cell suicide program triggered by farnesyl transferase inhibition. Cancer Biol Ther. 2007;6:1422-7 pubmed
|
| Newcomb E, Lukyanov Y, Schnee T, Esencay M, Fischer I, Hong D, et al. The geldanamycin analogue 17-allylamino-17-demethoxygeldanamycin inhibits the growth of GL261 glioma cells in vitro and in vivo. Anticancer Drugs. 2007;18:875-82 pubmed
|
| Lee K, Song K. Actin dysfunction activates ERK1/2 and delays entry into mitosis in mammalian cells. Cell Cycle. 2007;6:1487-95 pubmed
|
| Raina K, Singh R, Agarwal R, Agarwal C. Oral grape seed extract inhibits prostate tumor growth and progression in TRAMP mice. Cancer Res. 2007;67:5976-82 pubmed
|
| Schepelmann S, Ogilvie L, Hedley D, Friedlos F, Martin J, Scanlon I, et al. Suicide gene therapy of human colon carcinoma xenografts using an armed oncolytic adenovirus expressing carboxypeptidase G2. Cancer Res. 2007;67:4949-55 pubmed
|
| Stegmeier F, Sowa M, Nalepa G, Gygi S, Harper J, Elledge S. The tumor suppressor CYLD regulates entry into mitosis. Proc Natl Acad Sci U S A. 2007;104:8869-74 pubmed
|
| Heffeter P, Jakupec M, Korner W, Chiba P, Pirker C, Dornetshuber R, et al. Multidrug-resistant cancer cells are preferential targets of the new antineoplastic lanthanum compound KP772 (FFC24). Biochem Pharmacol. 2007;73:1873-86 pubmed
|
| Draviam V, Stegmeier F, Nalepa G, Sowa M, Chen J, Liang A, et al. A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling. Nat Cell Biol. 2007;9:556-64 pubmed
|
| Lanzetti L, Margaria V, Melander F, Virgili L, Lee M, Bartek J, et al. Regulation of the Rab5 GTPase-activating protein RN-tre by the dual specificity phosphatase Cdc14A in human cells. J Biol Chem. 2007;282:15258-70 pubmed
|
| Morris M, Gros E, Aldrian Herrada G, Choob M, Archdeacon J, Heitz F, et al. A non-covalent peptide-based carrier for in vivo delivery of DNA mimics. Nucleic Acids Res. 2007;35:e49 pubmed
|
| Dornetshuber R, Heffeter P, Kamyar M, Peterbauer T, Berger W, Lemmens Gruber R. Enniatin exerts p53-dependent cytostatic and p53-independent cytotoxic activities against human cancer cells. Chem Res Toxicol. 2007;20:465-73 pubmed
|
| Taguchi N, Ishihara N, Jofuku A, Oka T, Mihara K. Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission. J Biol Chem. 2007;282:11521-9 pubmed
|
| Mateyak M, Zakian V. Human PIF helicase is cell cycle regulated and associates with telomerase. Cell Cycle. 2006;5:2796-804 pubmed
|
| Balasubramanian S, Eckert R. Curcumin suppresses AP1 transcription factor-dependent differentiation and activates apoptosis in human epidermal keratinocytes. J Biol Chem. 2007;282:6707-15 pubmed
|
| Yu T, Peng Y, Androphy E. Mitotic kinesin-like protein 2 binds and colocalizes with papillomavirus E2 during mitosis. J Virol. 2007;81:1736-45 pubmed
|
| Pilkinton M, Sandoval R, Song J, Ness S, Colamonici O. Mip/LIN-9 regulates the expression of B-Myb and the induction of cyclin A, cyclin B, and CDK1. J Biol Chem. 2007;282:168-75 pubmed
|
| Culjkovic B, Topisirovic I, Skrabanek L, Ruiz Gutierrez M, Borden K. eIF4E is a central node of an RNA regulon that governs cellular proliferation. J Cell Biol. 2006;175:415-26 pubmed
|
| Reverte C, Benware A, Jones C, LaFlamme S. Perturbing integrin function inhibits microtubule growth from centrosomes, spindle assembly, and cytokinesis. J Cell Biol. 2006;174:491-7 pubmed
|
| Dangi S, Chen F, Shapiro P. Activation of extracellular signal-regulated kinase (ERK) in G2 phase delays mitotic entry through p21CIP1. Cell Prolif. 2006;39:261-79 pubmed
|
| Vassilev L, Tovar C, Chen S, Knezevic D, Zhao X, Sun H, et al. Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1. Proc Natl Acad Sci U S A. 2006;103:10660-5 pubmed
|
| Coisy Quivy M, Disson O, Roure V, Muchardt C, Blanchard J, Dantonel J. Role for Brm in cell growth control. Cancer Res. 2006;66:5069-76 pubmed
|
| Korgun E, Celik Ozenci C, Acar N, Cayli S, Desoye G, Demir R. Location of cell cycle regulators cyclin B1, cyclin A, PCNA, Ki67 and cell cycle inhibitors p21, p27 and p57 in human first trimester placenta and deciduas. Histochem Cell Biol. 2006;125:615-24 pubmed
|
| Morris K, Schang L, Brindley D. Lipid phosphate phosphatase-2 activity regulates S-phase entry of the cell cycle in Rat2 fibroblasts. J Biol Chem. 2006;281:9297-306 pubmed
|
| Jeganathan K, Malureanu L, van Deursen J. The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation. Nature. 2005;438:1036-9 pubmed
|
| Heffeter P, Jakupec M, Körner W, Wild S, von Keyserlingk N, Elbling L, et al. Anticancer activity of the lanthanum compound [tris(1,10-phenanthroline)lanthanum(III)]trithiocyanate (KP772; FFC24). Biochem Pharmacol. 2006;71:426-40 pubmed
|
| Knauf J, Ouyang B, Knudsen E, Fukasawa K, Babcock G, Fagin J. Oncogenic RAS induces accelerated transition through G2/M and promotes defects in the G2 DNA damage and mitotic spindle checkpoints. J Biol Chem. 2006;281:3800-9 pubmed
|
| Haraguchi K, Hayashi T, Jimbo T, Yamamoto T, Akiyama T. Role of the kinesin-2 family protein, KIF3, during mitosis. J Biol Chem. 2006;281:4094-9 pubmed
|
| Bellanger S, Blachon S, Mechali F, Bonne Andrea C, Thierry F. High-risk but not low-risk HPV E2 proteins bind to the APC activators Cdh1 and Cdc20 and cause genomic instability. Cell Cycle. 2005;4:1608-15 pubmed publisher
|
| Paronetto M, Zalfa F, Botti F, Geremia R, Bagni C, Sette C. The nuclear RNA-binding protein Sam68 translocates to the cytoplasm and associates with the polysomes in mouse spermatocytes. Mol Biol Cell. 2006;17:14-24 pubmed
|
| Shen G, Xu C, Chen C, Hebbar V, Kong A. p53-independent G1 cell cycle arrest of human colon carcinoma cells HT-29 by sulforaphane is associated with induction of p21CIP1 and inhibition of expression of cyclin D1. Cancer Chemother Pharmacol. 2006;57:317-27 pubmed
|
| Niida H, Tsuge S, Katsuno Y, Konishi A, Takeda N, Nakanishi M. Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe. J Biol Chem. 2005;280:39246-52 pubmed
|
| Balciunaite E, Spektor A, Lents N, Cam H, te Riele H, Scime A, et al. Pocket protein complexes are recruited to distinct targets in quiescent and proliferating cells. Mol Cell Biol. 2005;25:8166-78 pubmed
|
| Schmidt M, Budirahardja Y, Klompmaker R, Medema R. Ablation of the spindle assembly checkpoint by a compound targeting Mps1. EMBO Rep. 2005;6:866-72 pubmed
|
| Liu X, Guo Y, Li Y, Jiang Y, Chubb S, Azuma A, et al. Molecular basis for G2 arrest induced by 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine and consequences of checkpoint abrogation. Cancer Res. 2005;65:6874-81 pubmed
|
| Soghoian D, Jayaraman V, Silane M, Berenstein A, Jayaraman T. Inositol 1,4,5-trisphosphate receptor phosphorylation in breast cancer. Tumour Biol. 2005;26:207-12 pubmed
|
| Herman Antosiewicz A, Singh S. Checkpoint kinase 1 regulates diallyl trisulfide-induced mitotic arrest in human prostate cancer cells. J Biol Chem. 2005;280:28519-28 pubmed
|
| Fukuda T, Mishina Y, Walker M, DiAugustine R. Conditional transgenic system for mouse aurora a kinase: degradation by the ubiquitin proteasome pathway controls the level of the transgenic protein. Mol Cell Biol. 2005;25:5270-81 pubmed
|
| Chen H, Tang C, Chen C, Tang T. Overexpression of an Aurora-C kinase-deficient mutant disrupts the Aurora-B/INCENP complex and induces polyploidy. J Biomed Sci. 2005;12:297-310 pubmed
|
| Dangi S, Shapiro P. Cdc2-mediated inhibition of epidermal growth factor activation of the extracellular signal-regulated kinase pathway during mitosis. J Biol Chem. 2005;280:24524-31 pubmed
|
| Lacrima K, Valentini A, Lambertini C, Taborelli M, Rinaldi A, Zucca E, et al. In vitro activity of cyclin-dependent kinase inhibitor CYC202 (Seliciclib, R-roscovitine) in mantle cell lymphomas. Ann Oncol. 2005;16:1169-76 pubmed
|
| He G, Siddik Z, Huang Z, Wang R, Koomen J, Kobayashi R, et al. Induction of p21 by p53 following DNA damage inhibits both Cdk4 and Cdk2 activities. Oncogene. 2005;24:2929-43 pubmed
|
| Gupta B, Levchenko T, Torchilin V. Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides. Adv Drug Deliv Rev. 2005;57:637-51 pubmed
|
| Fujii Yamamoto H, Kim J, Arai K, Masai H. Cell cycle and developmental regulations of replication factors in mouse embryonic stem cells. J Biol Chem. 2005;280:12976-87 pubmed
|
| Wei J, Chou Y, Ou Y, Yeh Y, Tyan S, Sun T, et al. TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68. J Biol Chem. 2005;280:7748-57 pubmed
|
| Morris C, Jalinot P. Silencing of human Int-6 impairs mitosis progression and inhibits cyclin B-Cdk1 activation. Oncogene. 2005;24:1203-11 pubmed
|
| Goshima G, Kiyomitsu T, Yoda K, Yanagida M. Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway. J Cell Biol. 2003;160:25-39 pubmed
|
| Levesque A, Compton D. The chromokinesin Kid is necessary for chromosome arm orientation and oscillation, but not congression, on mitotic spindles. J Cell Biol. 2001;154:1135-46 pubmed
|