product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
HSP 70/HSC 70 (W27) Antibody
catalog :
sc-24
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
W27
reactivity :
redtail notho, human, mouse, rat, bee
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 125
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig 2h
Ma S, Mangala L, Hu W, Bayaktar E, Yokoi A, Hu W, et al. CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance. Cell Rep. 2021;36:109549 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3d, 3e
  • western blot; mouse; 1:1000; loading ...; fig 3d
Shen C, Hsieh C, Jiang K, Lin C, Chiang N, Li T, et al. AUY922 induces retinal toxicity through attenuating TRPM1. J Biomed Sci. 2021;28:55 pubmed publisher
  • western blot; mouse; loading ...; fig 2a
Kashyap R, Balzano M, Lechat B, Lambaerts K, Egea Jimenez A, Lembo F, et al. Syntenin-knock out reduces exosome turnover and viral transduction. Sci Rep. 2021;11:4083 pubmed publisher
  • immunohistochemistry; human; 1:200; fig 4
Hondius D, Koopmans F, Leistner C, Pita Illobre D, Peferoen Baert R, Marbus F, et al. The proteome of granulovacuolar degeneration and neurofibrillary tangles in Alzheimer's disease. Acta Neuropathol. 2021;141:341-358 pubmed publisher
  • western blot; human; 1:5000; loading ...; fig 6a
Pathak T, Gueguinou M, Walter V, Delierneux C, Johnson M, Zhang X, et al. Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis. elife. 2020;9: pubmed publisher
  • western blot; mouse; loading ...; fig 3c
Kuo I, Lee J, Wang Y, Chiang H, Huang C, Hsieh P, et al. Potential enhancement of host immunity and anti-tumor efficacy of nanoscale curcumin and resveratrol in colorectal cancers by modulated electro- hyperthermia. BMC Cancer. 2020;20:603 pubmed publisher
  • western blot; mouse; loading ...; fig 1b
Inouye S, Hatori Y, Kubo T, Saito S, Kitamura H, Akagi R. NRF2 and HSF1 coordinately regulate heme oxygenase-1 expression. Biochem Biophys Res Commun. 2018;506:7-11 pubmed publisher
  • western blot; mouse; loading ...; fig 4i
  • western blot; human; loading ...; fig 4h
Gerber T, Murawala P, Knapp D, Masselink W, Schuez M, Hermann S, et al. Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration. Science. 2018;362: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 7i
Fujimoto M, Takii R, Katiyar A, Srivastava P, Nakai A. Poly(ADP-Ribose) Polymerase 1 Promotes the Human Heat Shock Response by Facilitating Heat Shock Transcription Factor 1 Binding to DNA. Mol Cell Biol. 2018;38: pubmed publisher
  • western blot; human; fig s4g
Aneichyk T, Hendriks W, Yadav R, Shin D, Gao D, Vaine C, et al. Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly. Cell. 2018;172:897-909.e21 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s3c
  • western blot; mouse; loading ...; fig s3a
  • western blot; human; loading ...; fig s2b
Zhao T, Hong Y, Yin P, Li S, Li X. Differential HspBP1 expression accounts for the greater vulnerability of neurons than astrocytes to misfolded proteins. Proc Natl Acad Sci U S A. 2017;114:E7803-E7811 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 1
Zhang Q, Ma C, Oberli A, Zinz A, Engels S, Przyborski J. Proteomic analysis of exported chaperone/co-chaperone complexes of P. falciparum reveals an array of complex protein-protein interactions. Sci Rep. 2017;7:42188 pubmed publisher
  • western blot; human; loading ...; fig s3a
Melchionna R, Iapicca P, Di Modugno F, Trono P, Sperduti I, Fassan M, et al. The pattern of hMENA isoforms is regulated by TGF-?1 in pancreatic cancer and may predict patient outcome. Oncoimmunology. 2016;5:e1221556 pubmed publisher
  • immunohistochemistry; mouse; 1:50; loading ...; fig s6g
Nagaraj R, Sharpley M, Chi F, Braas D, Zhou Y, Kim R, et al. Nuclear Localization of Mitochondrial TCA Cycle Enzymes as a Critical Step in Mammalian Zygotic Genome Activation. Cell. 2017;168:210-223.e11 pubmed publisher
  • western blot; human; fig 6d
Seo B, Min K, Woo S, Choe M, Choi K, Lee Y, et al. Inhibition of Cathepsin S Induces Mitochondrial ROS That Sensitizes TRAIL-Mediated Apoptosis Through p53-Mediated Downregulation of Bcl-2 and c-FLIP. Antioxid Redox Signal. 2017;27:215-233 pubmed publisher
  • western blot; human; loading ...; fig 2a
Fritsch J, Fickers R, Klawitter J, Särchen V, Zingler P, Adam D, et al. TNF induced cleavage of HSP90 by cathepsin D potentiates apoptotic cell death. Oncotarget. 2016;7:75774-75789 pubmed publisher
  • immunohistochemistry; mouse; fig s3
Yamanaka T, Tosaki A, Miyazaki H, Kurosawa M, Koike M, Uchiyama Y, et al. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Sci Rep. 2016;6:34575 pubmed publisher
  • western blot; human; loading ...; fig 5a
Szymanska M, Fosdahl A, Nikolaysen F, Pedersen M, Grandal M, Stang E, et al. A combination of two antibodies recognizing non-overlapping epitopes of HER2 induces kinase activity-dependent internalization of HER2. J Cell Mol Med. 2016;20:1999-2011 pubmed publisher
  • western blot; human; fig 3
Ansari M, Haqqi T. Interleukin-1β induced Stress Granules Sequester COX-2 mRNA and Regulates its Stability and Translation in Human OA Chondrocytes. Sci Rep. 2016;6:27611 pubmed publisher
  • western blot; rat; fig 5e
Lin Y, Warren C, Li J, McKinsey T, Russell B. Myofibril growth during cardiac hypertrophy is regulated through dual phosphorylation and acetylation of the actin capping protein CapZ. Cell Signal. 2016;28:1015-24 pubmed publisher
  • western blot; mouse; 1:1000; fig 8
Dhar S, Kumar A, Zhang L, Rimando A, Lage J, Lewin J, et al. Dietary pterostilbene is a novel MTA1-targeted chemopreventive and therapeutic agent in prostate cancer. Oncotarget. 2016;7:18469-84 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500; fig 2
Ojima H, Masugi Y, Tsujikawa H, Emoto K, Fujii Nishimura Y, Hatano M, et al. Early hepatocellular carcinoma with high-grade atypia in small vaguely nodular lesions. Cancer Sci. 2016;107:543-50 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 4
Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, et al. Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nat Immunol. 2015;16:1235-44 pubmed publisher
  • western blot; mouse
Shi C, Huang X, Zhang B, Zhu D, Luo H, Lu Q, et al. The Inhibition of Heat Shock Protein 90 Facilitates the Degradation of Poly-Alanine Expanded Poly (A) Binding Protein Nuclear 1 via the Carboxyl Terminus of Heat Shock Protein 70-Interacting Protein. PLoS ONE. 2015;10:e0138936 pubmed publisher
  • western blot; human; fig 2
Serban A, Stanca L, Geicu O, Dinischiotu A. AGEs-Induced IL-6 Synthesis Precedes RAGE Up-Regulation in HEK 293 Cells: An Alternative Inflammatory Mechanism?. Int J Mol Sci. 2015;16:20100-17 pubmed publisher
  • western blot; human; fig 4,5,6
Wu Y, Chen H, Lu J, Zhang M, Zhang R, Duan T, et al. Acetylation-dependent function of human single-stranded DNA binding protein 1. Nucleic Acids Res. 2015;43:7878-87 pubmed publisher
  • western blot; human; 1:1000; fig 1
Frühbeis C, Helmig S, Tug S, Simon P, Krämer Albers E. Physical exercise induces rapid release of small extracellular vesicles into the circulation. J Extracell Vesicles. 2015;4:28239 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 5b
Sung B, Ketova T, Hoshino D, Zijlstra A, Weaver A. Directional cell movement through tissues is controlled by exosome secretion. Nat Commun. 2015;6:7164 pubmed publisher
  • western blot; human
Pospichalova V, Svoboda J, Dave Z, Kotrbova A, Kaiser K, Klemová D, et al. Simplified protocol for flow cytometry analysis of fluorescently labeled exosomes and microvesicles using dedicated flow cytometer. J Extracell Vesicles. 2015;4:25530 pubmed publisher
  • flow cytometry; human
Dudek Perić A, Ferreira G, Muchowicz A, Wouters J, Prada N, Martin S, et al. Antitumor immunity triggered by melphalan is potentiated by melanoma cell surface-associated calreticulin. Cancer Res. 2015;75:1603-14 pubmed publisher
  • western blot; human
Kim H, Jung G. Reactive oxygen species increase HEPN1 expression via activation of the XBP1 transcription factor. FEBS Lett. 2014;588:4413-21 pubmed publisher
  • western blot; redtail notho; 1:1000
Wang X, Chang Q, Wang Y, Su F, Zhang S. Late-onset temperature reduction can retard the aging process in aged fish via a combined action of an anti-oxidant system and the insulin/insulin-like growth factor 1 signaling pathway. Rejuvenation Res. 2014;17:507-17 pubmed publisher
  • western blot; rat; 1:500
Carloni S, Albertini M, Galluzzi L, Buonocore G, Proietti F, Balduini W. Increased autophagy reduces endoplasmic reticulum stress after neonatal hypoxia-ischemia: role of protein synthesis and autophagic pathways. Exp Neurol. 2014;255:103-12 pubmed publisher
  • western blot; human; loading ...; fig 2b
Xia Q, Cai Y, Peng R, Wu G, Shi Y, Jiang W. The CDK1 inhibitor RO3306 improves the response of BRCA-pro?cient breast cancer cells to PARP inhibition. Int J Oncol. 2014;44:735-44 pubmed publisher
  • western blot; bee ; 1:1000
Hsu C, Chuang Y, Chan Y. Changes in cellular degradation activity in young and old worker honeybees (Apis mellifera). Exp Gerontol. 2014;50:128-36 pubmed publisher
  • western blot; human; 1:1000
Armstrong A, Mattsson N, Appelqvist H, Janefjord C, Sandin L, Agholme L, et al. Lysosomal network proteins as potential novel CSF biomarkers for Alzheimer's disease. Neuromolecular Med. 2014;16:150-60 pubmed publisher
  • western blot; human; fig 8b
Alfonso Pérez T, Domínguez Sánchez M, Garcia Dominguez M, Reyes J. Cytoplasmic interaction of the tumour suppressor protein hSNF5 with dynamin-2 controls endocytosis. Oncogene. 2014;33:3064-74 pubmed publisher
  • western blot; human
Zhong X, Ding J, Adams J, Ghosh G, Fu X. Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones. Genes Dev. 2009;23:482-95 pubmed publisher
Cato L, Neeb A, Sharp A, Buzon V, Ficarro S, Yang L, et al. Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer. elife. 2017;6: pubmed publisher
Choe C, Shin Y, Kim C, Choi S, Lee J, Kim S, et al. Crosstalk with cancer-associated fibroblasts induces resistance of non-small cell lung cancer cells to epidermal growth factor receptor tyrosine kinase inhibition. Onco Targets Ther. 2015;8:3665-78 pubmed publisher
Lu C, Hsu C. Ambient temperature reduction extends lifespan via activating cellular degradation activity in an annual fish (Nothobranchius rachovii). Age (Dordr). 2015;37:33 pubmed publisher
Dossena M, Bedini G, Rusmini P, Giorgetti E, Canazza A, Tosetti V, et al. Human adipose-derived mesenchymal stem cells as a new model of spinal and bulbar muscular atrophy. PLoS ONE. 2014;9:e112746 pubmed publisher
Tsuzura H, Genda T, Sato S, Murata A, Kanemitsu Y, Narita Y, et al. Expression of aldo-keto reductase family 1 member b10 in the early stages of human hepatocarcinogenesis. Int J Mol Sci. 2014;15:6556-68 pubmed publisher
Chen J, Li C, Wang S. Periodic heat shock accelerated the chondrogenic differentiation of human mesenchymal stem cells in pellet culture. PLoS ONE. 2014;9:e91561 pubmed publisher
Przybyla B, Shafirstein G, Vishal S, Dennis R, Griffin R. Molecular changes in bone marrow, tumor and serum after conductive ablation of murine 4T1 breast carcinoma. Int J Oncol. 2014;44:600-8 pubmed publisher
Cushman Nick M, Bonini N, Shorter J. Hsp104 suppresses polyglutamine-induced degeneration post onset in a drosophila MJD/SCA3 model. PLoS Genet. 2013;9:e1003781 pubmed publisher
Xia D, Li W, Qian H, Yao S, Liu J, Qi X. Ischemia preconditioning is neuroprotective in a rat cerebral ischemic injury model through autophagy activation and apoptosis inhibition. Braz J Med Biol Res. 2013;46:580-8 pubmed publisher
Caligiuri I, Toffoli G, Giordano A, Rizzolio F. pRb controls estrogen receptor alpha protein stability and activity. Oncotarget. 2013;4:875-83 pubmed
Lu C, Lei L, Peng B, Tang L, Ding H, Gong S, et al. Chlamydia trachomatis GlgA is secreted into host cell cytoplasm. PLoS ONE. 2013;8:e68764 pubmed publisher
Park S, Choi H, Nam K, Na J, Huh C, Park K. Immediate induction of heat shock proteins is not protective against cryopreservation in normal human fibroblasts. Cryo Letters. 2013;34:239-47 pubmed
Rappa F, Unti E, Baiamonte P, Cappello F, Scibetta N. Different immunohistochemical levels of Hsp60 and Hsp70 in a subset of brain tumors and putative role of Hsp60 in neuroepithelial tumorigenesis. Eur J Histochem. 2013;57:e20 pubmed publisher
Kostourou V, Lechertier T, Reynolds L, Lees D, Baker M, Jones D, et al. FAK-heterozygous mice display enhanced tumour angiogenesis. Nat Commun. 2013;4:2020 pubmed publisher
Kim E, Jeong H, Yun H, Baek K, Kwon N, Park K, et al. Geranylgeranylacetone inhibits melanin synthesis via ERK activation in Mel-Ab cells. Life Sci. 2013;93:226-32 pubmed publisher
Gao B, Zhang X, Han R, Zhang T, Chen C, Qin Z, et al. The endoplasmic reticulum stress inhibitor salubrinal inhibits the activation of autophagy and neuroprotection induced by brain ischemic preconditioning. Acta Pharmacol Sin. 2013;34:657-66 pubmed publisher
Gantke T, Boussouf S, Janzen J, Morrice N, Howell S, Mühlberger E, et al. Ebola virus VP35 induces high-level production of recombinant TPL-2-ABIN-2-NF-?B1 p105 complex in co-transfected HEK-293 cells. Biochem J. 2013;452:359-65 pubmed publisher
Boiani M, Daniel C, Liu X, Hogarty M, Marnett L. The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737. J Biol Chem. 2013;288:6980-90 pubmed publisher
Hou S, Lei L, Yang Z, Qi M, Liu Q, Zhong G. Chlamydia trachomatis outer membrane complex protein B (OmcB) is processed by the protease CPAF. J Bacteriol. 2013;195:951-7 pubmed publisher
Coco M, Caggia S, Musumeci G, Perciavalle V, Graziano A, Pannuzzo G, et al. Sodium L-lactate differently affects brain-derived neurothrophic factor, inducible nitric oxide synthase, and heat shock protein 70 kDa production in human astrocytes and SH-SY5Y cultures. J Neurosci Res. 2013;91:313-20 pubmed publisher
Rao U, Hood B, Jones Laughner J, Sun M, Conrads T. Distinct profiles of oxidative stress-related and matrix proteins in adult bone and soft tissue osteosarcoma and desmoid tumors: a proteomics study. Hum Pathol. 2013;44:725-33 pubmed publisher
Willmer T, Contu L, Blatch G, Edkins A. Knockdown of Hop downregulates RhoC expression, and decreases pseudopodia formation and migration in cancer cell lines. Cancer Lett. 2013;328:252-60 pubmed publisher
Lei L, Li Z, Zhong G. Rottlerin-mediated inhibition of Chlamydia trachomatis growth and uptake of sphingolipids is independent of p38-regulated/activated protein kinase (PRAK). PLoS ONE. 2012;7:e44733 pubmed publisher
Sabirzhanov B, Stoica B, Hanscom M, Piao C, Faden A. Over-expression of HSP70 attenuates caspase-dependent and caspase-independent pathways and inhibits neuronal apoptosis. J Neurochem. 2012;123:542-54 pubmed publisher
La Montagna R, Caligiuri I, Maranta P, Lucchetti C, Esposito L, Paggi M, et al. Androgen receptor serine 81 mediates Pin1 interaction and activity. Cell Cycle. 2012;11:3415-20 pubmed publisher
Gong X, Luo T, Deng P, Liu Z, Xiu J, Shi H, et al. Stress-induced interaction between p38 MAPK and HSP70. Biochem Biophys Res Commun. 2012;425:357-62 pubmed publisher
Han D, Choi M, Jung K, Lee H, Park J, Ohn T, et al. Proteomic analysis of the copper ion-induced stress response in a human embryonic carcinoma cell line. Int J Toxicol. 2012;31:397-406 pubmed publisher
Cai M, Wang X, Zhang J, Han H, Liu C, Bei J, et al. Expression of heat shock protein 70 in nasopharyngeal carcinomas: different expression patterns correlate with distinct clinical prognosis. J Transl Med. 2012;10:96 pubmed publisher
Rizzolio F, Caligiuri I, Lucchetti C, Fratamico R, Tomei V, Gallo G, et al. Dissecting Pin1 and phospho-pRb regulation. J Cell Physiol. 2013;228:73-7 pubmed publisher
Inoue T, Kudo M, Komuta M, Hayaishi S, Ueda T, Takita M, et al. Assessment of Gd-EOB-DTPA-enhanced MRI for HCC and dysplastic nodules and comparison of detection sensitivity versus MDCT. J Gastroenterol. 2012;47:1036-47 pubmed publisher
Sheng R, Liu X, Zhang L, Gao B, Han R, Wu Y, et al. Autophagy regulates endoplasmic reticulum stress in ischemic preconditioning. Autophagy. 2012;8:310-25 pubmed publisher
Tomasello G, Sciume C, Rappa F, Rodolico V, Zerilli M, Martorana A, et al. Hsp10, Hsp70, and Hsp90 immunohistochemical levels change in ulcerative colitis after therapy. Eur J Histochem. 2011;55:e38 pubmed publisher
Barut A, Barut F, Kandemir N, Aktunc E, Arikan I, Harma M, et al. Placental chorangiosis: the association with oxidative stress and angiogenesis. Gynecol Obstet Invest. 2012;73:141-51 pubmed publisher
Rylander M, Stafford R, Hazle J, Whitney J, Diller K. Heat shock protein expression and temperature distribution in prostate tumours treated with laser irradiation and nanoshells. Int J Hyperthermia. 2011;27:791-801 pubmed publisher
Lei L, Qi M, Budrys N, Schenken R, Zhong G. Localization of Chlamydia trachomatis hypothetical protein CT311 in host cell cytoplasm. Microb Pathog. 2011;51:101-9 pubmed publisher
Wu X, Lei L, Gong S, Chen D, Flores R, Zhong G. The chlamydial periplasmic stress response serine protease cHtrA is secreted into host cell cytosol. BMC Microbiol. 2011;11:87 pubmed publisher
Qi M, Lei L, Gong S, Liu Q, DeLisa M, Zhong G. Chlamydia trachomatis secretion of an immunodominant hypothetical protein (CT795) into host cell cytoplasm. J Bacteriol. 2011;193:2498-509 pubmed publisher
Qi M, Gong S, Lei L, Liu Q, Zhong G. A Chlamydia trachomatis OmcB C-terminal fragment is released into the host cell cytoplasm and is immunogenic in humans. Infect Immun. 2011;79:2193-203 pubmed publisher
Zhang B, Huang B, Guan H, Zhang S, Xu Q, He X, et al. Proteomic profiling revealed the functional networks associated with mitotic catastrophe of HepG2 hepatoma cells induced by 6-bromine-5-hydroxy-4-methoxybenzaldehyde. Toxicol Appl Pharmacol. 2011;252:307-17 pubmed publisher
Appelqvist H, Nilsson C, Garner B, Brown A, Kågedal K, Ollinger K. Attenuation of the lysosomal death pathway by lysosomal cholesterol accumulation. Am J Pathol. 2011;178:629-39 pubmed publisher
Gong S, Lei L, Chang X, Belland R, Zhong G. Chlamydia trachomatis secretion of hypothetical protein CT622 into host cell cytoplasm via a secretion pathway that can be inhibited by the type III secretion system inhibitor compound 1. Microbiology. 2011;157:1134-44 pubmed publisher
Cotogni P, Bini R, Trombetta A, Olivero G. Pyrrolidine dithiocarbamate modulates HSP70, iNOS, and apoptosis during hemorrhagic shock resuscitation in rats. J Invest Surg. 2010;23:295-302 pubmed publisher
Um H, Kang E, Koo J, Kim H, Jin Lee -, Kim E, et al. Treadmill exercise represses neuronal cell death in an aged transgenic mouse model of Alzheimer's disease. Neurosci Res. 2011;69:161-73 pubmed publisher
Rylander M, Feng Y, Zimmermann K, Diller K. Measurement and mathematical modeling of thermally induced injury and heat shock protein expression kinetics in normal and cancerous prostate cells. Int J Hyperthermia. 2010;26:748-64 pubmed publisher
Cwiklinska H, Mycko M, Szymanska B, Matysiak M, Selmaj K. Aberrant stress-induced Hsp70 expression in immune cells in multiple sclerosis. J Neurosci Res. 2010;88:3102-10 pubmed publisher
Chien V, Aitken J, Zhang S, Buchanan C, Hickey A, Brittain T, et al. The chaperone proteins HSP70, HSP40/DnaJ and GRP78/BiP suppress misfolding and formation of ?-sheet-containing aggregates by human amylin: a potential role for defective chaperone biology in Type 2 diabetes. Biochem J. 2010;432:113-21 pubmed publisher
Federico M, Symonds C, Bagella L, Rizzolio F, Fanale D, Russo A, et al. R-Roscovitine (Seliciclib) prevents DNA damage-induced cyclin A1 upregulation and hinders non-homologous end-joining (NHEJ) DNA repair. Mol Cancer. 2010;9:208 pubmed publisher
Lin S, Hsueh C, Yu S, Su C, Shum W, Yeh K, et al. HLJ1 is a novel caspase-3 substrate and its expression enhances UV-induced apoptosis in non-small cell lung carcinoma. Nucleic Acids Res. 2010;38:6148-58 pubmed publisher
Barut F, Barut A, Dogan Gun B, Kandemir N, Aktunc E, Harma M, et al. Expression of heat shock protein 70 and endothelial nitric oxide synthase in placental tissue of preeclamptic and intrauterine growth-restricted pregnancies. Pathol Res Pract. 2010;206:651-6 pubmed publisher
Zapletal C, Fallsehr C, Reidel M, Löffler T, Gebhard M, Golling M, et al. Induction of HSP70 shows differences in protection against I/R injury derived by ischemic preconditioning and intermittent clamping. Microvasc Res. 2010;80:365-71 pubmed publisher
Han D, Kang S, Park O, Cho J, Won C, Park H, et al. Polychlorinated biphenyls have inhibitory effect on testicular steroidogenesis by downregulation of P450(17alpha) and P450(scc). Toxicol Ind Health. 2010;26:287-96 pubmed publisher
Nalvarte I, Schwend T, Gustafsson J. Proteomics analysis of the estrogen receptor alpha receptosome. Mol Cell Proteomics. 2010;9:1411-22 pubmed publisher
Cho J, Um H, Kang E, Cho I, Kim C, Cho J, et al. The combination of exercise training and alpha-lipoic acid treatment has therapeutic effects on the pathogenic phenotypes of Alzheimer's disease in NSE/APPsw-transgenic mice. Int J Mol Med. 2010;25:337-46 pubmed
Behrends M, Martinez Palli G, Niemann C, Cohen S, Ramachandran R, Hirose R. Acute hyperglycemia worsens hepatic ischemia/reperfusion injury in rats. J Gastrointest Surg. 2010;14:528-35 pubmed publisher
Hsu C, Chiu Y. Ambient temperature influences aging in an annual fish (Nothobranchius rachovii). Aging Cell. 2009;8:726-37 pubmed publisher
Corsino P, HORENSTEIN N, Ostrov D, Rowe T, Law M, Barrett A, et al. A novel class of cyclin-dependent kinase inhibitors identified by molecular docking act through a unique mechanism. J Biol Chem. 2009;284:29945-55 pubmed publisher
Ozacmak V, Barut F, Ozacmak H. Melatonin provides neuroprotection by reducing oxidative stress and HSP70 expression during chronic cerebral hypoperfusion in ovariectomized rats. J Pineal Res. 2009;47:156-63 pubmed publisher
Brusa D, Garetto S, Chiorino G, Scatolini M, Migliore E, Camussi G, et al. Post-apoptotic tumors are more palatable to dendritic cells and enhance their antigen cross-presentation activity. Vaccine. 2008;26:6422-32 pubmed publisher
Zhang S, Miller J, Stolz D, Serpero L, Zhao W, Gozal D, et al. Type I epithelial cells are the main target of whole-body hypoxic preconditioning in the lung. Am J Respir Cell Mol Biol. 2009;40:332-9 pubmed publisher
Li Z, Chen D, Zhong Y, Wang S, Zhong G. The chlamydial plasmid-encoded protein pgp3 is secreted into the cytosol of Chlamydia-infected cells. Infect Immun. 2008;76:3415-28 pubmed publisher
Lee Y, Lee J, Moon H, Jung J, Sharma M, Park B, et al. Differential effect of oxidative stress on the apoptosis of early and late passage human diploid fibroblasts: implication of heat shock protein 60. Cell Biochem Funct. 2008;26:502-8 pubmed publisher
Bao X, Liu G. Bicyclol: a novel antihepatitis drug with hepatic heat shock protein 27/70-inducing activity and cytoprotective effects in mice. Cell Stress Chaperones. 2008;13:347-55 pubmed publisher
Yamanaka T, Miyazaki H, Oyama F, Kurosawa M, Washizu C, Doi H, et al. Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor. EMBO J. 2008;27:827-39 pubmed publisher
Cheng W, Shivshankar P, Li Z, Chen L, Yeh I, Zhong G. Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection. Infect Immun. 2008;76:515-22 pubmed
Erata G, Kocak Toker N, Durlanik O, Kadioglu A, Aktan G, Aykac Toker G. The role of heat shock protein 70 (Hsp 70) in male infertility: is it a line of defense against sperm DNA fragmentation?. Fertil Steril. 2008;90:322-7 pubmed
Tanimura S, Hirano A, Hashizume J, Yasunaga M, Kawabata T, Ozaki K, et al. Anticancer drugs up-regulate HspBP1 and thereby antagonize the prosurvival function of Hsp70 in tumor cells. J Biol Chem. 2007;282:35430-9 pubmed
Ramp U, Mahotka C, Heikaus S, Shibata T, Grimm M, Willers R, et al. Expression of heat shock protein 70 in renal cell carcinoma and its relation to tumor progression and prognosis. Histol Histopathol. 2007;22:1099-107 pubmed publisher
Wang S, Xie W, Rylander M, Tucker P, Aggarwal S, Diller K. HSP70 kinetics study by continuous observation of HSP-GFP fusion protein expression on a perfusion heating stage. Biotechnol Bioeng. 2008;99:146-54 pubmed
Della Ragione F, Cucciolla V, Borriello A, Oliva A, Perrotta S. Erythropoietin receptors on cancer cells: a still open question. J Clin Oncol. 2007;25:1812-3; author reply 1815 pubmed
Di Tommaso L, Franchi G, Park Y, Fiamengo B, Destro A, Morenghi E, et al. Diagnostic value of HSP70, glypican 3, and glutamine synthetase in hepatocellular nodules in cirrhosis. Hepatology. 2007;45:725-34 pubmed
Jiang H, He J, Pu S, Tang C, Xu G. Heat shock protein 70 is translocated to lipid droplets in rat adipocytes upon heat stimulation. Biochim Biophys Acta. 2007;1771:66-74 pubmed
Mileo A, Piombino E, Severino A, Tritarelli A, Paggi M, Lombardi D. Multiple interference of the human papillomavirus-16 E7 oncoprotein with the functional role of the metastasis suppressor Nm23-H1 protein. J Bioenerg Biomembr. 2006;38:215-25 pubmed
Voss A, Krebs D, Thomas T. C3G regulates the size of the cerebral cortex neural precursor population. EMBO J. 2006;25:3652-63 pubmed
Gottschalg E, Moore N, Ryan A, Travis L, Waller R, Pratt S, et al. Phenotypic anchoring of arsenic and cadmium toxicity in three hepatic-related cell systems reveals compound- and cell-specific selective up-regulation of stress protein expression: implications for fingerprint profiling of cytotoxicity. Chem Biol Interact. 2006;161:251-61 pubmed
Wang J, Wang S, Manzer R, McConville G, Mason R. Ozone induces oxidative stress in rat alveolar type II and type I-like cells. Free Radic Biol Med. 2006;40:1914-28 pubmed
Mohan J, Gandhi A, Bhavya B, Rashmi R, Karunagaran D, Indu R, et al. Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol. J Biol Chem. 2006;281:17599-611 pubmed
Wei H, Campbell W, Vander Heide R. Heat shock-induced cardioprotection activates cytoskeletal-based cell survival pathways. Am J Physiol Heart Circ Physiol. 2006;291:H638-47 pubmed
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product information
Catalog Number :
sc-24
Product Name :
HSP 70/HSC 70 (W27) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
W27
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
HSP 70
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), FCM
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA