Published Application/Species/Sample/Dilution | Reference |
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- western blot; mouse; 1:500; loading ...; fig 8d
| Edwards G, Perkins G, Kim K, Kong Y, Lee Y, Choi S, et al. Loss of AKAP1 triggers Drp1 dephosphorylation-mediated mitochondrial fission and loss in retinal ganglion cells. Cell Death Dis. 2020;11:254 pubmed publisher
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- western blot; human; 1:200; loading ...; fig 3b
| Moncsek A, Al Suraih M, Trussoni C, O Hara S, Splinter P, Zuber C, et al. Targeting senescent cholangiocytes and activated fibroblasts with B-cell lymphoma-extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2-/- ) mice. Hepatology. 2017;: pubmed publisher
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- western blot; dogs; loading ...; fig s5b
| Zhang K, Myllymäki S, Gao P, Devarajan R, Kytölä V, Nykter M, et al. Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with αV-Class integrins to promote EMT. Oncogene. 2017;36:5681-5694 pubmed publisher
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- western blot; mouse; loading ...; fig 2b
| Xiao F, Zhang J, Zhang C, An W. Hepatic stimulator substance inhibits calcium overflow through the mitochondria-associated membrane compartment during nonalcoholic steatohepatitis. Lab Invest. 2017;97:289-301 pubmed publisher
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- western blot; pigs ; fig 3
| Zhao X, Song X, Bai X, Fei N, Huang Y, Zhao Z, et al. miR-27b attenuates apoptosis induced by transmissible gastroenteritis virus (TGEV) infection via targeting runt-related transcription factor 1 (RUNX1). Peerj. 2016;4:e1635 pubmed publisher
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| Su C, Sun F, Cunningham R, Rybalchenko N, Singh M. ERK5/KLF4 signaling as a common mediator of the neuroprotective effects of both nerve growth factor and hydrogen peroxide preconditioning. Age (Dordr). 2014;36:9685 pubmed publisher
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- immunoprecipitation; mouse
- western blot; mouse
| Bai L, Chen J, McEachern D, Liu L, Zhou H, Aguilar A, et al. BM-1197: a novel and specific Bcl-2/Bcl-xL inhibitor inducing complete and long-lasting tumor regression in vivo. PLoS ONE. 2014;9:e99404 pubmed publisher
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- western blot; mouse; fig 4
| Ying Y, Kim J, Westphal S, Long K, Padanilam B. Targeted deletion of p53 in the proximal tubule prevents ischemic renal injury. J Am Soc Nephrol. 2014;25:2707-16 pubmed publisher
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| Guerzoni C, Amatori S, Giorgi L, Manara M, Landuzzi L, Lollini P, et al. An aza-macrocycle containing maltolic side-arms (maltonis) as potential drug against human pediatric sarcomas. BMC Cancer. 2014;14:137 pubmed publisher
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- immunoprecipitation; human
| Annibaldi A, Heulot M, Martinou J, Widmann C. TAT-RasGAP317-326-mediated tumor cell death sensitization can occur independently of Bax and Bak. Apoptosis. 2014;19:719-33 pubmed publisher
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- immunocytochemistry; mouse; 1:200
| Faccenda D, Tan C, Seraphim A, Duchen M, Campanella M. IF1 limits the apoptotic-signalling cascade by preventing mitochondrial remodelling. Cell Death Differ. 2013;20:686-97 pubmed publisher
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- immunocytochemistry; human; 1:500
| Cazanave S, Mott J, Bronk S, Werneburg N, Fingas C, Meng X, et al. Death receptor 5 signaling promotes hepatocyte lipoapoptosis. J Biol Chem. 2011;286:39336-48 pubmed publisher
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- immunoprecipitation; rhesus macaque
- western blot; rhesus macaque
| Martin Latil S, Mousson L, Autret A, Colbere Garapin F, Blondel B. Bax is activated during rotavirus-induced apoptosis through the mitochondrial pathway. J Virol. 2007;81:4457-64 pubmed
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| Preston A, Rogers A, Sharp M, Mitchell G, Toruno C, Barney B, et al. Elephant TP53-RETROGENE 9 induces transcription-independent apoptosis at the mitochondria. Cell Death Discov. 2023;9:66 pubmed publisher
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| Schmitt H, Fehrman R, Maes M, Yang H, Guo L, Schlamp C, et al. Increased Susceptibility and Intrinsic Apoptotic Signaling in Neurons by Induced HDAC3 Expression. Invest Ophthalmol Vis Sci. 2021;62:14 pubmed publisher
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| Maes M, Grosser J, Fehrman R, Schlamp C, Nickells R. Completion of BAX recruitment correlates with mitochondrial fission during apoptosis. Sci Rep. 2019;9:16565 pubmed publisher
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| Robinson E, Aguiar S, Kouwenhoven W, Starmans D, von Oerthel L, Smidt M, et al. Survival of midbrain dopamine neurons depends on the Bcl2 factor Mcl1. Cell Death Discov. 2018;4:107 pubmed publisher
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| Nie X, Zheng J, Ricupero C, He L, Jiao K, Mao J. mTOR acts as a pivotal signaling hub for neural crest cells during craniofacial development. PLoS Genet. 2018;14:e1007491 pubmed publisher
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| Shim M, Kim K, Bu J, Nam H, Jeong S, Park T, et al. Elevated intracellular cAMP exacerbates vulnerability to oxidative stress in optic nerve head astrocytes. Cell Death Dis. 2018;9:285 pubmed publisher
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| Matsuura K, Huang N, Cocce K, Zhang L, Kornbluth S. Downregulation of the proapoptotic protein MOAP-1 by the UBR5 ubiquitin ligase and its role in ovarian cancer resistance to cisplatin. Oncogene. 2017;36:1698-1706 pubmed publisher
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| Zhang L, Wu H, Sun G, Xu X, Sun X, Cao L. Trichloromethane fraction of Incarvillea compacta induces lytic cytotoxicity and apoptosis in Epstein-Barr virus-positive gastric cancer AGS cells. BMC Complement Altern Med. 2016;16:344 pubmed publisher
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| Strappazzon F, Di Rita A, Cianfanelli V, D Orazio M, Nazio F, Fimia G, et al. Prosurvival AMBRA1 turns into a proapoptotic BH3-like protein during mitochondrial apoptosis. Autophagy. 2016;12:963-75 pubmed publisher
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| Haschka M, Soratroi C, Kirschnek S, Hacker G, Hilbe R, Geley S, et al. The NOXA-MCL1-BIM axis defines lifespan on extended mitotic arrest. Nat Commun. 2015;6:6891 pubmed publisher
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| Yang C, Matsuura K, Huang N, Robeson A, Huang B, Zhang L, et al. Fatty acid synthase inhibition engages a novel caspase-2 regulatory mechanism to induce ovarian cancer cell death. Oncogene. 2015;34:3264-72 pubmed publisher
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| Sizova O, Shinde V, Lenox A, Gorbatyuk M. Modulation of cellular signaling pathways in P23H rhodopsin photoreceptors. Cell Signal. 2014;26:665-672 pubmed publisher
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| Song J, Ryu S, Cho Y, Kim Y, Lee B, Lee S, et al. Wip1 suppresses apoptotic cell death through direct dephosphorylation of BAX in response to ?-radiation. Cell Death Dis. 2013;4:e744 pubmed publisher
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| Song T, Liang F, Zhang Z, Liu Y, Sheng H, Xie M. S1 kills MCF-7/ADR cells more than MCF-7 cells: A protective mechanism of endoplasmic reticulum stress. Biomed Pharmacother. 2013;67:731-6 pubmed publisher
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| Song T, Xue Z, Zhang Z, Shen X, Li X. Pan-BH3 mimetic S1 exhibits broad-spectrum antitumour effects by cooperation between Bax and Bak. Basic Clin Pharmacol Toxicol. 2013;113:145-51 pubmed publisher
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| Gwak M, Cao L, Li L, Zuo Z. Isoflurane preconditioning reduces oxygen-glucose deprivation-induced neuronal injury via B-cell lymphoma 2 protein. Environ Toxicol Pharmacol. 2011;31:262-5 pubmed publisher
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| Zhang Z, Song T, Zhang T, Gao J, Wu G, An L, et al. A novel BH3 mimetic S1 potently induces Bax/Bak-dependent apoptosis by targeting both Bcl-2 and Mcl-1. Int J Cancer. 2011;128:1724-35 pubmed publisher
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| Zheng Y, Zhou M, Ye A, Li Q, Bai Y, Zhang Q. The conformation change of Bcl-2 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in SGC7901 human gastric cancer cells. World J Surg Oncol. 2010;8:31 pubmed publisher
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| Jia G, Kwon M, Liang H, Mortensen J, Nilakantan V, Sweeney W, et al. Chronic treatment with lisinopril decreases proliferative and apoptotic pathways in autosomal recessive polycystic kidney disease. Pediatr Nephrol. 2010;25:1139-46 pubmed publisher
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| Wang X, Viswanath R, Zhao J, Tang S, Hewlett I. Changes in the level of apoptosis-related proteins in Jurkat cells infected with HIV-1 versus HIV-2. Mol Cell Biochem. 2010;337:175-83 pubmed publisher
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| Liu J, Zhou W, Li S, Sun Z, Lin B, Lang Y, et al. Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues. Cancer Res. 2008;68:8871-80 pubmed publisher
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| Chai W, Zhu X, Li S, Fan J, Chen B. Role of Bcl-2 family members in caspase-3/9-dependent apoptosis during Pseudomonas aeruginosa infection in U937 cells. Apoptosis. 2008;13:833-43 pubmed publisher
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| Xu Q, Ohara N, Liu J, Nakabayashi K, DeManno D, Chwalisz K, et al. Selective progesterone receptor modulator asoprisnil induces endoplasmic reticulum stress in cultured human uterine leiomyoma cells. Am J Physiol Endocrinol Metab. 2007;293:E1002-11 pubmed
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| Autret A, Martin Latil S, Mousson L, Wirotius A, Petit F, Arnoult D, et al. Poliovirus induces Bax-dependent cell death mediated by c-Jun NH2-terminal kinase. J Virol. 2007;81:7504-16 pubmed
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| Shankar S, Srivastava R. Bax and Bak genes are essential for maximum apoptotic response by curcumin, a polyphenolic compound and cancer chemopreventive agent derived from turmeric, Curcuma longa. Carcinogenesis. 2007;28:1277-86 pubmed
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| Zhang Y, McLaughlin R, Goodyer C, LeBlanc A. Selective cytotoxicity of intracellular amyloid beta peptide1-42 through p53 and Bax in cultured primary human neurons. J Cell Biol. 2002;156:519-29 pubmed
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