product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
nestin (10c2) Antibody
catalog :
sc-23927
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10C2
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 40
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:100; fig 2c
Sighel D, Notarangelo M, Aibara S, Re A, Ricci G, Guida M, et al. Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth. Cell Rep. 2021;35:109024 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 6c
Arber C, Lovejoy C, Harris L, Willumsen N, Alatza A, Casey J, et al. Familial Alzheimer's Disease Mutations in PSEN1 Lead to Premature Human Stem Cell Neurogenesis. Cell Rep. 2021;34:108615 pubmed publisher
  • flow cytometry; human; fig s1b
Torres A, Vargas Y, Uribe D, Jaramillo C, Gleisner A, Salazar Onfray F, et al. Adenosine A3 receptor elicits chemoresistance mediated by multiple resistance-associated protein-1 in human glioblastoma stem-like cells. Oncotarget. 2016;7:67373-67386 pubmed publisher
  • immunocytochemistry; human; fig 7
Kushwaha R, Jagadish N, Kustagi M, Mendiratta G, Seandel M, Soni R, et al. Mechanism and Role of SOX2 Repression in Seminoma: Relevance to Human Germline Specification. Stem Cell Reports. 2016;6:772-783 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig 4
Vinci L, Ravarino A, Fanos V, Naccarato A, Senes G, Gerosa C, et al. Immunohistochemical markers of neural progenitor cells in the early embryonic human cerebral cortex. Eur J Histochem. 2016;60:2563 pubmed publisher
  • immunocytochemistry; human; fig 1
Yap M, Tang Y, Yeo Y, Lim W, Lim L, Tan K, et al. Pluripotent Human embryonic stem cell derived neural lineages for in vitro modelling of enterovirus 71 infection and therapy. Virol J. 2016;13:5 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 1d
Wang W, Long L, Wang L, Tan C, Fei X, Chen L, et al. Knockdown of Cathepsin L promotes radiosensitivity of glioma stem cells both in vivo and in vitro. Cancer Lett. 2016;371:274-84 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
  • western blot; human; fig 2
Joseph J, van Roosmalen I, Busschers E, Tomar T, Conroy S, Eggens Meijer E, et al. Serum-Induced Differentiation of Glioblastoma Neurospheres Leads to Enhanced Migration/Invasion Capacity That Is Associated with Increased MMP9. PLoS ONE. 2015;10:e0145393 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 9
Martínez Revollar G, Garay E, Martín Tapia D, Nava P, Huerta M, Lopez Bayghen E, et al. Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways. Exp Cell Res. 2015;339:67-80 pubmed publisher
  • immunocytochemistry; human; 1:250; loading ...; fig s7
Fessler E, Borovski T, Medema J. Endothelial cells induce cancer stem cell features in differentiated glioblastoma cells via bFGF. Mol Cancer. 2015;14:157 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig S4
Tate C, Mc Entire J, Pallini R, Vakana E, Wyss L, Blosser W, et al. A BMP7 Variant Inhibits Tumor Angiogenesis In Vitro and In Vivo through Direct Modulation of Endothelial Cell Biology. PLoS ONE. 2015;10:e0125697 pubmed publisher
  • immunohistochemistry - paraffin section; human
  • western blot; human; 1:500
Joseph J, Conroy S, Tomar T, Eggens Meijer E, Bhat K, Copray S, et al. TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion. Cell Death Dis. 2014;5:e1443 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig 4
Bodi I, Curran O, Selway R, Elwes R, Burrone J, Laxton R, et al. Two cases of multinodular and vacuolating neuronal tumour. Acta Neuropathol Commun. 2014;2:7 pubmed publisher
  • immunohistochemistry - paraffin section; human
Ishida M, Iwai M, Yoshida K, Kagotani A, Okabe H. Signet-ring cell melanoma with sentinel lymph node metastasis: A case report with immunohistochemical analysis and review of the clinicopathological features. Oncol Lett. 2014;7:65-68 pubmed
  • immunohistochemistry - paraffin section; human
Sellheyer K, Krahl D. Spatiotemporal expression pattern of neuroepithelial stem cell marker nestin suggests a role in dermal homeostasis, neovasculogenesis, and tumor stroma development: a study on embryonic and adult human skin. J Am Acad Dermatol. 2010;63:93-113 pubmed publisher
Chen W, Ding Y, Liu D, Lu Z, Wang Y, Yuan Y. Kaposi's sarcoma-associated herpesvirus vFLIP promotes MEndT to generate hybrid M/E state for tumorigenesis. PLoS Pathog. 2021;17:e1009600 pubmed publisher
Townshend R, Shao Y, Wang S, Cortez C, Esfahani S, Spence J, et al. Effect of Cell Spreading on Rosette Formation by Human Pluripotent Stem Cell-Derived Neural Progenitor Cells. Front Cell Dev Biol. 2020;8:588941 pubmed publisher
Lee J, Lee J, Cho Y. Peroxisome Proliferator-Activated Receptor α Agonist and Its Target Nanog Cooperate to Induce Pluripotency. J Clin Med. 2018;7: pubmed publisher
Witusik Perkowska M, Zakrzewska M, Sikorska B, Papierz W, Jaskolski D, Szemraj J, et al. Glioblastoma-derived cells in vitro unveil the spectrum of drug resistance capability - comparative study of tumour chemosensitivity in different culture systems. Biosci Rep. 2017;37: pubmed publisher
Cruceru M, Enciu A, Popa A, Albulescu R, Neagu M, Tanase C, et al. Signal transduction molecule patterns indicating potential glioblastoma therapy approaches. Onco Targets Ther. 2013;6:1737-49 pubmed publisher
Ladstein R, Bachmann I, Straume O, Akslen L. Nestin expression is associated with aggressive cutaneous melanoma of the nodular type. Mod Pathol. 2014;27:396-401 pubmed publisher
Suman S, Rodriguez O, Winters T, Fornace A, Albanese C, Datta K. Therapeutic and space radiation exposure of mouse brain causes impaired DNA repair response and premature senescence by chronic oxidant production. Aging (Albany NY). 2013;5:607-22 pubmed
Korkolopoulou P, Levidou G, El Habr E, Adamopoulos C, Fragkou P, Boviatsis E, et al. Sox11 expression in astrocytic gliomas: correlation with nestin/c-Met/IDH1-R132H expression phenotypes, p-Stat-3 and survival. Br J Cancer. 2013;108:2142-52 pubmed publisher
Romano S, Staibano S, Greco A, Brunetti A, Nappo G, Ilardi G, et al. FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential. Cell Death Dis. 2013;4:e578 pubmed publisher
Cakici C, Buyrukcu B, Duruksu G, Haliloglu A, Aksoy A, Isik A, et al. Recovery of fertility in azoospermia rats after injection of adipose-tissue-derived mesenchymal stem cells: the sperm generation. Biomed Res Int. 2013;2013:529589 pubmed publisher
Kruger K, Stefansson I, Collett K, Arnes J, Aas T, Akslen L. Microvessel proliferation by co-expression of endothelial nestin and Ki-67 is associated with a basal-like phenotype and aggressive features in breast cancer. Breast. 2013;22:282-8 pubmed publisher
Park S, Kim E, Koh S, Maeng S, Lee W, Lim J, et al. Dopaminergic differentiation of neural progenitors derived from placental mesenchymal stem cells in the brains of Parkinson's disease model rats and alleviation of asymmetric rotational behavior. Brain Res. 2012;1466:158-66 pubmed publisher
Bodi I, Selway R, Bannister P, Doey L, Mullatti N, Elwes R, et al. Diffuse form of dysembryoplastic neuroepithelial tumour: the histological and immunohistochemical features of a distinct entity showing transition to dysembryoplastic neuroepithelial tumour and ganglioglioma. Neuropathol Appl Neurobiol. 2012;38:411-25 pubmed publisher
Trabzuni D, Ryten M, Walker R, Smith C, Imran S, Ramasamy A, et al. Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies. J Neurochem. 2011;119:275-82 pubmed publisher
Casabona F, Priano V, Vallerino V, Cogliandro A, Lavagnino G. New surgical approach to lichen sclerosus of the vulva: the role of adipose-derived mesenchymal cells and platelet-rich plasma in tissue regeneration. Plast Reconstr Surg. 2010;126:210e-211e pubmed publisher
Bakos R, Maier T, Besch R, Mestel D, Ruzicka T, Sturm R, et al. Nestin and SOX9 and SOX10 transcription factors are coexpressed in melanoma. Exp Dermatol. 2010;19:e89-94 pubmed publisher
Tiede S, Kloepper J, Ernst N, Poeggeler B, Kruse C, Paus R. Nestin in human skin: exclusive expression in intramesenchymal skin compartments and regulation by leptin. J Invest Dermatol. 2009;129:2711-20 pubmed publisher
Gravdal K, Halvorsen O, Haukaas S, Akslen L. Proliferation of immature tumor vessels is a novel marker of clinical progression in prostate cancer. Cancer Res. 2009;69:4708-15 pubmed publisher
Rieske P, Golanska E, Zakrzewska M, Piaskowski S, Hulas Bigoszewska K, Wolańczyk M, et al. Arrested neural and advanced mesenchymal differentiation of glioblastoma cells-comparative study with neural progenitors. BMC Cancer. 2009;9:54 pubmed publisher
Edwards K. Welcome to the first issue of the seventh volume of the Plant Biotechnology Journal. Plant Biotechnol J. 2009;7:1 pubmed publisher
Rieske P, Augelli B, Stawski R, Gaughan J, Azizi S, Krynska B. A population of human brain cells expressing phenotypic markers of more than one lineage can be induced in vitro to differentiate into mesenchymal cells. Exp Cell Res. 2009;315:462-73 pubmed publisher
Corsino P, Davis B, Nørgaard P, Parker N, Law M, Dunn W, et al. Mammary tumors initiated by constitutive Cdk2 activation contain an invasive basal-like component. Neoplasia. 2008;10:1240-52 pubmed
Flammiger A, Besch R, Cook A, Maier T, Sturm R, Berking C. SOX9 and SOX10 but not BRN2 are required for nestin expression in human melanoma cells. J Invest Dermatol. 2009;129:945-53 pubmed publisher
Witusik M, Piaskowski S, Hulas Bigoszewska K, Zakrzewska M, Gresner S, Azizi S, et al. Successful elimination of non-neural cells and unachievable elimination of glial cells by means of commonly used cell culture manipulations during differentiation of GFAP and SOX2 positive neural progenitors (NHA) to neuronal cells. BMC Biotechnol. 2008;8:56 pubmed publisher
Rosellini A, Papini S, Giannarini C, Nardi M, Revoltella R. Human conjunctival epithelial precursor cells and their progeny in 3D organotypic culture. Int J Dev Biol. 2007;51:739-43 pubmed
product information
Catalog Number :
sc-23927
Product Name :
nestin (10c2) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
10c2
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
nestin
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA