product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Hemoglobin β (37-8) Antibody
catalog :
sc-21757
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
37-8
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 22
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:200; loading ...; fig 2e
Creed M, Baldeosingh R, Eberly C, Schlee C, Kim M, Cutler J, et al. PAX-SIX-EYA-DACH Network modulates GATA-FOG function in fly hematopoiesis and human erythropoiesis. Development. 2019;: pubmed publisher
  • western blot; human; loading ...; fig 2d
Cai L, Bai H, Mahairaki V, Gao Y, He C, Wen Y, et al. A Universal Approach to Correct Various HBB Gene Mutations in Human Stem Cells for Gene Therapy of Beta-Thalassemia and Sickle Cell Disease. Stem Cells Transl Med. 2018;7:87-97 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 2a
Trakarnsanga K, Griffiths R, Wilson M, Blair A, Satchwell T, Meinders M, et al. An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells. Nat Commun. 2017;8:14750 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Baksi S, Tripathi A, Singh N. Alpha-synuclein modulates retinal iron homeostasis by facilitating the uptake of transferrin-bound iron: Implications for visual manifestations of Parkinson's disease. Free Radic Biol Med. 2016;97:292-306 pubmed publisher
  • western blot; human; 1:200; fig 7
Breveglieri G, Mancini I, Bianchi N, Lampronti I, Salvatori F, Fabbri E, et al. Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β -Globin Gene with the IVSI-6 Thalassemia Mutation. Biomed Res Int. 2015;2015:687635 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2
Romero Z, Campo Fernandez B, Wherley J, Kaufman M, Urbinati F, Cooper A, et al. The human ankyrin 1 promoter insulator sustains gene expression in a β-globin lentiviral vector in hematopoietic stem cells. Mol Ther Methods Clin Dev. 2015;2:15012 pubmed publisher
  • immunocytochemistry; human; 1:75
  • western blot; human; 1:100
Emara M, Turner A, Allalunis Turner J. Adult, embryonic and fetal hemoglobin are expressed in human glioblastoma cells. Int J Oncol. 2014;44:514-20 pubmed publisher
  • western blot; human; 1:500
Peng L, Liu J, Li Y, Huang Z, Wang P, Gu Y, et al. Serum proteomics analysis and comparisons using iTRAQ in the progression of hepatitis B. Exp Ther Med. 2013;6:1169-1176 pubmed
  • flow cytometry; human
Huang X, Shah S, Wang J, Ye Z, Dowey S, Tsang K, et al. Extensive ex vivo expansion of functional human erythroid precursors established from umbilical cord blood cells by defined factors. Mol Ther. 2014;22:451-463 pubmed publisher
Starlard Davenport A, Smith A, Vu L, Li B, Pace B. MIR29B mediates epigenetic mechanisms of HBG gene activation. Br J Haematol. 2019;186:91-100 pubmed publisher
Muniz L, Davidson L, West S. Poly(A) Polymerase and the Nuclear Poly(A) Binding Protein, PABPN1, Coordinate the Splicing and Degradation of a Subset of Human Pre-mRNAs. Mol Cell Biol. 2015;35:2218-30 pubmed publisher
Roversi F, da Cunha A, Brugnerotto A, Carazzolle M, de Albuquerque D, Lanaro C, et al. Gene expression analysis of the Brazilian type of hereditary persistence of fetal hemoglobin: identification of genes that could be related to ?-globin activation. Hemoglobin. 2013;37:516-35 pubmed publisher
Yocum A, Steiner L, Seidel N, Cline A, Rout E, Lin J, et al. A tissue-specific chromatin loop activates the erythroid ankyrin-1 promoter. Blood. 2012;120:3586-93 pubmed publisher
Costa F, Fedosyuk H, Neades R, de Los Rios J, Barbas C, Peterson K. Induction of Fetal Hemoglobin In Vivo Mediated by a Synthetic ?-Globin Zinc Finger Activator. Anemia. 2012;2012:507894 pubmed publisher
Park T, Zimmerlin L, Zambidis E. Efficient and simultaneous generation of hematopoietic and vascular progenitors from human induced pluripotent stem cells. Cytometry A. 2013;83:114-26 pubmed publisher
Capulli M, Angelucci A, Driouch K, Garcia T, Clément Lacroix P, Martella F, et al. Increased expression of a set of genes enriched in oxygen binding function discloses a predisposition of breast cancer bone metastases to generate metastasis spread in multiple organs. J Bone Miner Res. 2012;27:2387-98 pubmed publisher
Sjeklocha L, Park C, Wong P, Roney M, Belcher J, Kaufman D, et al. Erythroid-specific expression of ?-globin from Sleeping Beauty-transduced human hematopoietic progenitor cells. PLoS ONE. 2011;6:e29110 pubmed publisher
Xu J, Peng C, Sankaran V, Shao Z, Esrick E, Chong B, et al. Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing. Science. 2011;334:993-6 pubmed publisher
Wong S, Keyvanfar K, Wan Z, Kajigaya S, Young N, Zhi N. Establishment of an erythroid cell line from primary CD36+ erythroid progenitor cells. Exp Hematol. 2010;38:994-1005.e1-2 pubmed publisher
Suzuki Y, Takeda Y, Ikuta T. Immunoblotting conditions for human hemoglobin chains. Anal Biochem. 2008;378:218-20 pubmed publisher
Sekikawa T, Iwase S, Saito S, Arakawa Y, Agawa M, Horiguchi Yamada J, et al. JAS-R, a new megakaryo-erythroid leukemic cell line that secretes erythropoietin. Anticancer Res. 2006;26:843-50 pubmed
Onda M, Akaishi J, Asaka S, Okamoto J, Miyamoto S, Mizutani K, et al. Decreased expression of haemoglobin beta (HBB) gene in anaplastic thyroid cancer and recovery of its expression inhibits cell growth. Br J Cancer. 2005;92:2216-24 pubmed
product information
Catalog Number :
sc-21757
Product Name :
Hemoglobin β (37-8) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
37-8
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Hemoglobin beta
Specificity :
human
Uses :
WB, IP, IF, IHC(P), FCM
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA