product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
EMMPRIN (8D6) Antibody
catalog :
sc-21746
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
8D6
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 17
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 2b
Cai S, Hu T, Venkatesan M, Allam M, Schneider F, Ramalingam S, et al. Multiplexed protein profiling reveals spatial subcellular signaling networks. iScience. 2022;25:104980 pubmed publisher
  • western blot; human; loading ...; fig 5c, s7d
Heider M, Eichner R, Stroh J, Morath V, Kuisl A, Zecha J, et al. The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma. Mol Cell. 2021;: pubmed publisher
  • western blot; human; fig 2a
Zhu Y, Shi C, Bruins L, Wang X, Riggs D, Porter B, et al. Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4. Blood Cancer J. 2019;9:19 pubmed publisher
  • flow cytometry; human; fig 2
  • immunoprecipitation; human; fig 2
  • immunocytochemistry; human; fig 2
  • western blot; human; 1:200; fig 5
Eichner R, Heider M, Fernández Sáiz V, van Bebber F, Garz A, Lemeer S, et al. Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity. Nat Med. 2016;22:735-43 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 6a
Bhat N, Adams C, Chen Y, Bieber M, Teng N. Identification of Cell Surface Straight Chain Poly-N-Acetyl-Lactosamine Bearing Protein Ligands for VH4-34-Encoded Natural IgM Antibodies. J Immunol. 2015;195:5178-88 pubmed publisher
  • immunohistochemistry; human; 1:100; fig 2
Hemdan T, Malmström P, Jahnson S, Segersten U. Emmprin Expression Predicts Response and Survival following Cisplatin Containing Chemotherapy for Bladder Cancer: A Validation Study. J Urol. 2015;194:1575-81 pubmed publisher
Giebel N, de Jaime Soguero A, García Del Arco A, Landry J, Tietje M, Villacorta L, et al. USP42 protects ZNRF3/RNF43 from R-spondin-dependent clearance and inhibits Wnt signalling. EMBO Rep. 2021;22:e51415 pubmed publisher
Voss D, Spina R, Carter D, Lim K, Jeffery C, Bar E. Disruption of the monocarboxylate transporter-4-basigin interaction inhibits the hypoxic response, proliferation, and tumor progression. Sci Rep. 2017;7:4292 pubmed publisher
Kendrick A, Schafer J, Dzieciatkowska M, Nemkov T, D Alessandro A, Neelakantan D, et al. CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming. Oncotarget. 2017;8:6742-6762 pubmed publisher
To M, Peterson C, Roberts M, Counihan J, Wu T, Forster M, et al. Lipid disequilibrium disrupts ER proteostasis by impairing ERAD substrate glycan trimming and dislocation. Mol Biol Cell. 2017;28:270-284 pubmed publisher
El Rehim D, El Maqsoud N, El Hamid A, El Bab T, Galal E. Expression of extracellular matrix metalloproteinase inducer and fascin in urinary bladder cancer: Correlation with clinicopathological characteristics. Mol Clin Oncol. 2013;1:297-304 pubmed
Tian L, Zhang Y, Chen Y, Cai M, Dong H, Xiong L. EMMPRIN is an independent negative prognostic factor for patients with astrocytic glioma. PLoS ONE. 2013;8:e58069 pubmed publisher
Bi X, Liu J, He H, Ye Y, Han Z, Dai Q, et al. Extracellular matrix metalloproteinase inducer: a novel poor prognostic marker for human seminomas. Clin Transl Oncol. 2012;14:190-6 pubmed
Du Z, Hu C, Shao Q, Huang M, Kou C, Zhu X, et al. Upregulation of caveolin-1 and CD147 expression in nasopharyngeal carcinoma enhanced tumor cell migration and correlated with poor prognosis of the patients. Int J Cancer. 2009;125:1832-41 pubmed publisher
Umar A, Kang H, Timmermans A, Look M, Meijer van Gelder M, Den Bakker M, et al. Identification of a putative protein profile associated with tamoxifen therapy resistance in breast cancer. Mol Cell Proteomics. 2009;8:1278-94 pubmed publisher
Sillanpää S, Anttila M, Suhonen K, Hamalainen K, Turpeenniemi Hujanen T, Puistola U, et al. Prognostic significance of extracellular matrix metalloproteinase inducer and matrix metalloproteinase 2 in epithelial ovarian cancer. Tumour Biol. 2007;28:280-9 pubmed
Als A, Dyrskjøt L, von der Maase H, Koed K, Mansilla F, Toldbod H, et al. Emmprin and survivin predict response and survival following cisplatin-containing chemotherapy in patients with advanced bladder cancer. Clin Cancer Res. 2007;13:4407-14 pubmed
product information
Catalog Number :
sc-21746
Product Name :
EMMPRIN (8D6) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
8D6
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
EMMPRIN
Specificity :
human
Uses :
WB, IP, IF, IHC(P), FCM
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA