product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Fascin 1 (55K-2) Antibody
catalog :
sc-21743
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
55K-2
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 1c
Yu S, Cheng L, Tian D, Li Z, Yao F, Luo Y, et al. Fascin-1 is Highly Expressed Specifically in Microglia After Spinal Cord Injury and Regulates Microglial Migration. Front Pharmacol. 2021;12:729524 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 4b
Pocaterra A, Scattolin G, Romani P, Ament C, Ribback S, Chen X, et al. Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development. Commun Biol. 2021;4:763 pubmed publisher
  • immunocytochemistry; mouse; 1:20; loading ...; fig s11
Kage F, Winterhoff M, Dimchev V, Mueller J, Thalheim T, Freise A, et al. FMNL formins boost lamellipodial force generation. Nat Commun. 2017;8:14832 pubmed publisher
  • immunocytochemistry; human; 1:100
Liu Y, Jiang Y, Wang B, Hao J, Shang L, Zhang T, et al. A panel of protein markers for the early detection of lung cancer with bronchial brushing specimens. Cancer Cytopathol. 2014;122:833-41 pubmed publisher
  • western blot; human
Sun J, He H, Pillai S, Xiong Y, Challa S, Xu L, et al. GATA3 transcription factor abrogates Smad4 transcription factor-mediated fascin overexpression, invadopodium formation, and breast cancer cell invasion. J Biol Chem. 2013;288:36971-82 pubmed publisher
  • western blot; mouse; loading ...; fig s1f
Block J, Breitsprecher D, Kuhn S, Winterhoff M, Kage F, Geffers R, et al. FMNL2 drives actin-based protrusion and migration downstream of Cdc42. Curr Biol. 2012;22:1005-12 pubmed publisher
Miao Q, Hill M, Chen F, Mo Q, Ku A, Ramos C, et al. SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair. Nat Commun. 2019;10:4042 pubmed publisher
Saad A, Bijian K, Qiu D, da Silva S, Marques M, Chang C, et al. Insights into a novel nuclear function for Fascin in the regulation of the amino-acid transporter SLC3A2. Sci Rep. 2016;6:36699 pubmed publisher
Wang X, Shi L, Deng Y, Qu M, Mao S, Xu L, et al. Inhibition of leucine aminopeptidase 3 suppresses invasion of ovarian cancer cells through down-regulation of fascin and MMP-2/9. Eur J Pharmacol. 2015;768:116-22 pubmed publisher
El Rehim D, El Maqsoud N, El Hamid A, El Bab T, Galal E. Expression of extracellular matrix metalloproteinase inducer and fascin in urinary bladder cancer: Correlation with clinicopathological characteristics. Mol Clin Oncol. 2013;1:297-304 pubmed
Liu Y, Lin D, Xiao T, Ma Y, Hu Z, Zheng H, et al. An immunohistochemical analysis-based decision tree model for estimating the risk of lymphatic metastasis in pN0 squamous cell carcinomas of the lung. Histopathology. 2011;59:882-91 pubmed publisher
Sun J, He H, Xiong Y, Lu S, Shen J, Cheng A, et al. Fascin protein is critical for transforming growth factor ? protein-induced invasion and filopodia formation in spindle-shaped tumor cells. J Biol Chem. 2011;286:38865-75 pubmed publisher
Yasmeen A, Alachkar A, Dekhil H, Gambacorti Passerini C, Al Moustafa A. Locking Src/Abl Tyrosine Kinase Activities Regulate Cell Differentiation and Invasion of Human Cervical Cancer Cells Expressing E6/E7 Oncoproteins of High-Risk HPV. J Oncol. 2010;2010: pubmed publisher
Megiorni F, Indovina P, Mora B, Mazzilli M. Minor expression of fascin-1 gene (FSCN1) in NTera2 cells depleted of CREB-binding protein. Neurosci Lett. 2005;381:169-74 pubmed
product information
Catalog Number :
sc-21743
Product Name :
Fascin 1 (55K-2) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
55K-2
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Fascin
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA