product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Flightless I (116.40) Antibody
catalog :
sc-21716
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
116.40
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 10
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; mouse; fig 6
  • western blot; mouse; 1:1000; fig 6
Marei H, Carpy A, Macek B, Malliri A. Proteomic analysis of Rac1 signaling regulation by guanine nucleotide exchange factors. Cell Cycle. 2016;15:1961-74 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Turner C, Waters J, Jackson J, Arkell R, Cowin A. Fibroblast-specific upregulation of Flightless I impairs wound healing. Exp Dermatol. 2015;24:692-7 pubmed publisher
Marei H, Carpy A, Woroniuk A, Vennin C, White G, Timpson P, et al. Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration. Nat Commun. 2016;7:10664 pubmed publisher
Ruzehaji N, Grose R, Krumbiegel D, Zola H, Dasari P, Wallace H, et al. Cytoskeletal protein Flightless (Flii) is elevated in chronic and acute human wounds and wound fluid: neutralizing its activity in chronic but not acute wound fluid improves cellular proliferation. Eur J Dermatol. 2012;22:740-50 pubmed publisher
Jackson J, Kopecki Z, Adams D, Cowin A. Flii neutralizing antibodies improve wound healing in porcine preclinical studies. Wound Repair Regen. 2012;20:523-36 pubmed publisher
Mohammad I, Arora P, Naghibzadeh Y, Wang Y, Li J, Mascarenhas W, et al. Flightless I is a focal adhesion-associated actin-capping protein that regulates cell migration. FASEB J. 2012;26:3260-72 pubmed publisher
Lin C, Waters J, Powell B, Arkell R, Cowin A. Decreased expression of Flightless I, a gelsolin family member and developmental regulator, in early-gestation fetal wounds improves healing. Mamm Genome. 2011;22:341-52 pubmed publisher
Khositseth S, Pisitkun T, Slentz D, Wang G, Hoffert J, Knepper M, et al. Quantitative protein and mRNA profiling shows selective post-transcriptional control of protein expression by vasopressin in kidney cells. Mol Cell Proteomics. 2011;10:M110.004036 pubmed publisher
Adams D, Ruzehaji N, Strudwick X, Greenwood J, Campbell H, Arkell R, et al. Attenuation of Flightless I, an actin-remodelling protein, improves burn injury repair via modulation of transforming growth factor (TGF)-beta1 and TGF-beta3. Br J Dermatol. 2009;161:326-36 pubmed publisher
Adams D, Strudwick X, Kopecki Z, Hooper Jones J, Matthaei K, Campbell H, et al. Gender specific effects on the actin-remodelling protein Flightless I and TGF-beta1 contribute to impaired wound healing in aged skin. Int J Biochem Cell Biol. 2008;40:1555-69 pubmed publisher
product information
Catalog Number :
sc-21716
Product Name :
Flightless I (116.40) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
116.40
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Flightless I
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA