product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
CD68 (KP1) Antibody
catalog :
sc-20060
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
KP1
reactivity :
African green monkey, human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 41
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; tbl 3
Pulkka O, Viisanen L, Tynninen O, Laaksonen M, Reichardt P, Reichardt A, et al. Fibrinogen-like protein 2 in gastrointestinal stromal tumour. J Cell Mol Med. 2022;26:1083-1094 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 4
xc5 lgars A, Kemppinen L, Fair M xe4 kel xe4 R, Mustonen H, Haglund C, Jalkanen S. Stage I-IV Colorectal Cancer Prognosis Can Be Predicted by Type and Number of Intratumoral Macrophages and CLEVER-1+ Vessel Density. Cancers (Basel). 2021;13: pubmed publisher
  • immunohistochemistry; rat; loading ...; fig 7j
  • western blot; rat; fig 7h
Shi Y, Hu Y, Wang Y, Ma X, Tang L, Tao M, et al. Blockade of Autophagy Prevents the Development and Progression of Peritoneal Fibrosis. Front Pharmacol. 2021;12:724141 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 5m
Kimura K, Ramirez K, Nguyen T, Yamashiro Y, Sada A, Yanagisawa H. Contribution of PDGFRα-positive cells in maintenance and injury responses in mouse large vessels. Sci Rep. 2021;11:8683 pubmed publisher
  • immunohistochemistry; mouse; 1:50; loading ...; fig 7a
Li S, Zhu Z, Xue M, Pan X, Tong G, Yi X, et al. The protective effects of fibroblast growth factor 10 against hepatic ischemia-reperfusion injury in mice. Redox Biol. 2021;40:101859 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 6i
Song M, YEKU O, Rafiq S, Purdon T, Dong X, Zhu L, et al. Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages. Nat Commun. 2020;11:6298 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1c
Cho H, Lim Y, Kim J, Koh W, Song C, Kang M. Different macrophage polarization between drug-susceptible and multidrug-resistant pulmonary tuberculosis. BMC Infect Dis. 2020;20:81 pubmed publisher
  • immunohistochemistry - paraffin section; rat; loading ...; fig 4b
Zilberman Itskovich S, Abu Hamad R, Zarura R, Sova M, Hachmo Y, Stark M, et al. Human mesenchymal stromal cells ameliorate complement induced inflammatory cascade and improve renal functions in a rat model of ischemia-reperfusion induced acute kidney injury. PLoS ONE. 2019;14:e0222354 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 6a
Tsai C, Lin Y, Huang C, Shih C, Tsai Y, Tsao N, et al. Thrombomodulin regulates monocye differentiation via PKC? and ERK1/2 pathway in vitro and in atherosclerotic artery. Sci Rep. 2016;6:38421 pubmed publisher
  • western blot; human; loading ...
Baghel K, Tewari B, Shrivastava R, Malik S, Lone M, Jain N, et al. Macrophages promote matrix protrusive and invasive function of breast cancer cells via MIP-1? dependent upregulation of MYO3A gene in breast cancer cells. Oncoimmunology. 2016;5:e1196299 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200
Wang L, Xu D, Qiao Z, Shen L, Dai H, Ji Y. Follicular dendritic cell sarcoma of the spleen: A case report and review of the literature. Oncol Lett. 2016;12:2062-2064 pubmed
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 1c
Fan T, Warmoes M, Sun Q, Song H, Turchan Cholewo J, Martin J, et al. Distinctly perturbed metabolic networks underlie differential tumor tissue damages induced by immune modulator ?-glucan in a two-case ex vivo non-small-cell lung cancer study. Cold Spring Harb Mol Case Stud. 2016;2:a000893 pubmed publisher
  • immunohistochemistry - frozen section; African green monkey; fig 8A
Ploquin M, Madec Y, Casrouge A, Huot N, Passaes C, Lécuroux C, et al. Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset. PLoS Pathog. 2016;12:e1005774 pubmed publisher
  • immunohistochemistry - paraffin section; human; 4 ug/ml; fig 4
Koeppen A, Ramirez R, Becker A, Mazurkiewicz J. Dorsal root ganglia in Friedreich ataxia: satellite cell proliferation and inflammation. Acta Neuropathol Commun. 2016;4:46 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:300; fig 6
Tietz O, Wuest M, Marshall A, Glubrecht D, Hamann I, Wang M, et al. PET imaging of cyclooxygenase-2 (COX-2) in a pre-clinical colorectal cancer model. EJNMMI Res. 2016;6:37 pubmed publisher
  • immunohistochemistry; human; fig 1
Li X, Wu L, Li S, Zhou W, Wang M, Zuo G, et al. Effect of CD16a, the surface receptor of Kupffer cells, on the growth of hepatocellular carcinoma cells. Int J Mol Med. 2016;37:1465-74 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 3
Shankman L, Gomez D, Cherepanova O, Salmon M, Alencar G, Haskins R, et al. KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. Nat Med. 2015;21:628-37 pubmed publisher
  • immunohistochemistry - paraffin section; human
Koeppen A, Ramirez R, Becker A, Bjork S, Levi S, Santambrogio P, et al. The pathogenesis of cardiomyopathy in Friedreich ataxia. PLoS ONE. 2015;10:e0116396 pubmed publisher
  • immunohistochemistry - paraffin section; rat
  • immunohistochemistry - paraffin section; human
Fukuda M, Aoki T, Manabe T, Maekawa A, Shirakawa T, Kataoka H, et al. Exacerbation of intracranial aneurysm and aortic dissection in hypertensive rat treated with the prostaglandin F-receptor antagonist AS604872. J Pharmacol Sci. 2014;126:230-42 pubmed
Wu M, Ge Y, Wang E, Liao Q, Ren Z, Yu Y, et al. Enhancement of efferocytosis through biased FPR2 signaling attenuates intestinal inflammation. EMBO Mol Med. 2023;15:e17815 pubmed publisher
Garc xed a V xed lchez R, A xf1 azco Guenkova A, Dietmann S, L xf3 pez J, Mor xf3 n Calvente V, D Ambrosi S, et al. METTL1 promotes tumorigenesis through tRNA-derived fragment biogenesis in prostate cancer. Mol Cancer. 2023;22:119 pubmed publisher
Shin H, Jeong E, Lee J, An H, Jang H, Ahn Y, et al. Lipocalin-2 Deficiency Reduces Oxidative Stress and Neuroinflammation and Results in Attenuation of Kainic Acid-Induced Hippocampal Cell Death. Antioxidants (Basel). 2021;10: pubmed publisher
Wu M, Liu L, Wang E, Xiao H, Cai C, Wang J, et al. PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation. Autophagy. 2020;:1-16 pubmed publisher
Popovic D, Kocic G, Katic V, Zarubica A, Velickovic L, Ničković V, et al. Anthocyanins Protect Hepatocytes against CCl4-Induced Acute Liver Injury in Rats by Inhibiting Pro-inflammatory mediators, Polyamine Catabolism, Lipocalin-2, and Excessive Proliferation of Kupffer Cells. Antioxidants (Basel). 2019;8: pubmed publisher
Han Y, Shin K, Kim J, Khadka D, Kim H, Lee Y, et al. A maresin 1/RORα/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis. J Clin Invest. 2019;130:1684-1698 pubmed publisher
Ramírez Carracedo R, Tesoro L, Hernández I, Diez Mata J, Filice M, Toro R, et al. Non-Invasive Detection of Extracellular Matrix Metalloproteinase Inducer EMMPRIN, a New Therapeutic Target against Atherosclerosis, Inhibited by Endothelial Nitric Oxide. Int J Mol Sci. 2018;19: pubmed publisher
Wu Q, Chen J, Chen Y, Cai L, Wang X, Guo W, et al. The chemokine receptor CCR10 promotes inflammation-driven hepatocarcinogenesis via PI3K/Akt pathway activation. Cell Death Dis. 2018;9:232 pubmed publisher
Watanabe R, Shirai T, Namkoong H, Zhang H, Berry G, Wallis B, et al. Pyruvate controls the checkpoint inhibitor PD-L1 and suppresses T cell immunity. J Clin Invest. 2017;127:2725-2738 pubmed publisher
Darbinyan A, Major E, Morgello S, Holland S, Ryschkewitsch C, Monaco M, et al. BK virus encephalopathy and sclerosing vasculopathy in a patient with hypohidrotic ectodermal dysplasia and immunodeficiency. Acta Neuropathol Commun. 2016;4:73 pubmed publisher
Huang L, Li G, Feng X, Wang L. 15d-PGJ2 Reduced Microglia Activation and Alleviated Neurological Deficit of Ischemic Reperfusion in Diabetic Rat Model. Biomed Res Int. 2015;2015:864509 pubmed publisher
Cao W, Peters J, Nieman D, Sharma M, Watson T, Yu J. Macrophage subtype predicts lymph node metastasis in oesophageal adenocarcinoma and promotes cancer cell invasion in vitro. Br J Cancer. 2015;113:738-46 pubmed publisher
Genin M, Clement F, Fattaccioli A, Raes M, Michiels C. M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide. BMC Cancer. 2015;15:577 pubmed publisher
Huang H, Chen A, Wang T, Wang M, Ning X, He M, et al. Detecting cell-in-cell structures in human tumor samples by E-cadherin/CD68/CD45 triple staining. Oncotarget. 2015;6:20278-87 pubmed
Ramírez C, Lin C, Abdelmohsen K, Goedeke L, Yoon J, Madrigal Matute J, et al. RNA binding protein HuR regulates the expression of ABCA1. J Lipid Res. 2014;55:1066-76 pubmed publisher
Amanzada A, Malik I, Blaschke M, Khan S, Rahman H, Ramadori G, et al. Identification of CD68(+) neutrophil granulocytes in in vitro model of acute inflammation and inflammatory bowel disease. Int J Clin Exp Pathol. 2013;6:561-70 pubmed
Mehra S, Alvarez X, Didier P, Doyle L, Blanchard J, Lackner A, et al. Granuloma correlates of protection against tuberculosis and mechanisms of immune modulation by Mycobacterium tuberculosis. J Infect Dis. 2013;207:1115-27 pubmed publisher
Mogilenko D, Orlov S, Trulioff A, Ivanov A, Nagumanov V, Kudriavtsev I, et al. Endogenous apolipoprotein A-I stabilizes ATP-binding cassette transporter A1 and modulates Toll-like receptor 4 signaling in human macrophages. FASEB J. 2012;26:2019-30 pubmed publisher
Wang R, Zhang J, Chen S, Lu M, Luo X, Yao S, et al. Tumor-associated macrophages provide a suitable microenvironment for non-small lung cancer invasion and progression. Lung Cancer. 2011;74:188-96 pubmed publisher
Wang R, Lu M, Zhang J, Chen S, Luo X, Qin Y, et al. Increased IL-10 mRNA expression in tumor-associated macrophage correlated with late stage of lung cancer. J Exp Clin Cancer Res. 2011;30:62 pubmed publisher
Zhang W, Wang L, Zhou D, Cui Q, Zhao D, Wu Y. Expression of tumor-associated macrophages and vascular endothelial growth factor correlates with poor prognosis of peripheral T-cell lymphoma, not otherwise specified. Leuk Lymphoma. 2011;52:46-52 pubmed publisher
Shun C, Yeh C, Chang C, Wu S, Lien H, Chen J, et al. Activation of human valve interstitial cells by a viridians streptococci modulin induces chemotaxis of mononuclear cells. J Infect Dis. 2009;199:1488-96 pubmed publisher
product information
Catalog Number :
sc-20060
Product Name :
CD68 (KP1) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
KP1
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
CD68
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), FCM
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA