product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
CD3 (PC3/188A) Antibody
catalog :
sc-20047
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PC3/188A
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 29
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 5d
Guo D, Yamamoto M, Hernandez C, Khodadadi H, Baban B, Stranahan A. Beige adipocytes mediate the neuroprotective and anti-inflammatory effects of subcutaneous fat in obese mice. Nat Commun. 2021;12:4623 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 2a
Chen C, Wang D, Yu Y, Zhao T, Min N, Wu Y, et al. Legumain promotes tubular ferroptosis by facilitating chaperone-mediated autophagy of GPX4 in AKI. Cell Death Dis. 2021;12:65 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200
Wang L, Xu D, Qiao Z, Shen L, Dai H, Ji Y. Follicular dendritic cell sarcoma of the spleen: A case report and review of the literature. Oncol Lett. 2016;12:2062-2064 pubmed
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig s8a
Guo X, Sun X, Hu D, Wang Y, Fujioka H, Vyas R, et al. VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease. Nat Commun. 2016;7:12646 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5a
Abdullah C, Li Z, Wang X, Jin Z. Depletion of T lymphocytes ameliorates cardiac fibrosis in streptozotocin-induced diabetic cardiomyopathy. Int Immunopharmacol. 2016;39:251-264 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 1
Liu Y, Xia T, Jin C, Gu D, Yu J, Shi W, et al. FOXP3 and CEACAM6 expression and T cell infiltration in the occurrence and development of colon cancer. Oncol Lett. 2016;11:3693-3701 pubmed
  • flow cytometry; rat; 1:1000
Wang X, Zeng X, Yang B, Zhao S, Chen W, Guo X. Efficacy of thymosin α1 and interferon α for the treatment of severe acute pancreatitis in a rat model. Mol Med Rep. 2015;12:6775-81 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 6
Zhao H, Bauzon F, Bi E, Yu J, Fu H, Lu Z, et al. Substituting threonine 187 with alanine in p27Kip1 prevents pituitary tumorigenesis by two-hit loss of Rb1 and enhances humoral immunity in old age. J Biol Chem. 2015;290:5797-809 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 6
Li Z, Abdullah C, Jin Z. Inhibition of PKC-? preserves cardiac function and reduces fibrosis in streptozotocin-induced diabetic cardiomyopathy. Br J Pharmacol. 2014;171:2913-24 pubmed publisher
  • immunohistochemistry; mouse
Zhou D, Tan R, Lin L, Zhou L, Liu Y. Activation of hepatocyte growth factor receptor, c-met, in renal tubules is required for renoprotection after acute kidney injury. Kidney Int. 2013;84:509-20 pubmed publisher
  • immunohistochemistry; mouse
Giannopoulou M, Dai C, Tan X, Wen X, Michalopoulos G, Liu Y. Hepatocyte growth factor exerts its anti-inflammatory action by disrupting nuclear factor-kappaB signaling. Am J Pathol. 2008;173:30-41 pubmed publisher
Sun P, Wang Z, Liu W, Li M, Wei S, Xu Y, et al. Programmed death-1 mediates venous neointimal hyperplasia in humans and rats. Aging (Albany NY). 2021;13:16656-16666 pubmed publisher
Del Rio C, Cantarero I, Palomares B, Gómez Cañas M, Fernandez Ruiz J, Pavicic C, et al. VCE-004.3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPARγ- and CB2 receptor-dependent pathways. Br J Pharmacol. 2018;175:3813-3831 pubmed publisher
Overgaard N, Principe D, Schachtschneider K, Jakobsen J, Rund L, Grippo P, et al. Genetically Induced Tumors in the Oncopig Model Invoke an Antitumor Immune Response Dominated by Cytotoxic CD8β+ T Cells and Differentiated γδ T Cells Alongside a Regulatory Response Mediated by FOXP3+ T Cells and Immunoregulatory Molecules. Front Immunol. 2018;9:1301 pubmed publisher
Long Y, Zhen X, Zhu F, Hu Z, Lei W, Li S, et al. Hyperhomocysteinemia Exacerbates Cisplatin-induced Acute Kidney Injury. Int J Biol Sci. 2017;13:219-231 pubmed publisher
Luo F, Herrup K, Qi X, Yang Y. Inhibition of Drp1 hyper-activation is protective in animal models of experimental multiple sclerosis. Exp Neurol. 2017;292:21-34 pubmed publisher
Zhao S, Xu Z, Wang H, Reese B, Gushchina L, Jiang M, et al. Bioengineering of injectable encapsulated aggregates of pluripotent stem cells for therapy of myocardial infarction. Nat Commun. 2016;7:13306 pubmed publisher
Seemann S, Lupp A. Administration of AMD3100 in endotoxemia is associated with pro-inflammatory, pro-oxidative, and pro-apoptotic effects in vivo. J Biomed Sci. 2016;23:68 pubmed
Fanton d Andon M, Quellard N, Fernandez B, Ratet G, Lacroix Lamandé S, Vandewalle A, et al. Leptospira Interrogans induces fibrosis in the mouse kidney through Inos-dependent, TLR- and NLR-independent signaling pathways. PLoS Negl Trop Dis. 2014;8:e2664 pubmed publisher
Zhou Y, Fang L, Jiang L, Wen P, Cao H, He W, et al. Uric acid induces renal inflammation via activating tubular NF-?B signaling pathway. PLoS ONE. 2012;7:e39738 pubmed publisher
Sawatsky B, Wong X, Hinkelmann S, Cattaneo R, von Messling V. Canine distemper virus epithelial cell infection is required for clinical disease but not for immunosuppression. J Virol. 2012;86:3658-66 pubmed publisher
Li Y, Wen X, Liu Y. Tubular cell dedifferentiation and peritubular inflammation are coupled by the transcription regulator Id1 in renal fibrogenesis. Kidney Int. 2012;81:880-91 pubmed publisher
Bianchi M, Calvo V, Chasseing N, Lago N, Libertun C, Montaner A, et al. Oligodeoxynucleotide IMT504: lack of effect on immune parameters during islet regeneration in single dose streptozotocin-induced diabetes. Diabetes Metab Res Rev. 2012;28:156-63 pubmed publisher
Pillet S, Kobasa D, Meunier I, Gray M, Laddy D, Weiner D, et al. Cellular immune response in the presence of protective antibody levels correlates with protection against 1918 influenza in ferrets. Vaccine. 2011;29:6793-801 pubmed publisher
Doherty L, Kwon H, Taylor H. Regulation of tryptophan 2,3-dioxygenase by HOXA10 enhances embryo viability through serotonin signaling. Am J Physiol Endocrinol Metab. 2011;300:E86-93 pubmed publisher
Strissel K, DeFuria J, Shaul M, Bennett G, Greenberg A, Obin M. T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice. Obesity (Silver Spring). 2010;18:1918-25 pubmed publisher
Tan X, He W, Liu Y. Combination therapy with paricalcitol and trandolapril reduces renal fibrosis in obstructive nephropathy. Kidney Int. 2009;76:1248-57 pubmed publisher
Pillet S, von Messling V. Canine distemper virus selectively inhibits apoptosis progression in infected immune cells. J Virol. 2009;83:6279-87 pubmed publisher
Tan X, Wen X, Liu Y. Paricalcitol inhibits renal inflammation by promoting vitamin D receptor-mediated sequestration of NF-kappaB signaling. J Am Soc Nephrol. 2008;19:1741-52 pubmed publisher
product information
Catalog Number :
sc-20047
Product Name :
CD3 (PC3/188A) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
PC3/188A
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
CD313E0GL0RK4
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), FCM
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA