product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
CUG-BP1 (3B1) Antibody
catalog :
sc-20003
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3B1
reactivity :
human, mouse, chicken, Xenopus laevis
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, proximity ligation assay, RNA immunoprecipitation
citations: 23
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4c
  • western blot; mouse; 1:1000; loading ...; fig 4a
Shen X, Xu F, Li M, Wu S, Zhang J, Wang A, et al. miR-322/-503 rescues myoblast defects in myotonic dystrophy type 1 cell model by targeting CUG repeats. Cell Death Dis. 2020;11:891 pubmed publisher
  • western blot; human; loading ...; fig 4d
Valanejad L, Lewis K, Wright M, Jiang Y, D Souza A, Karns R, et al. FXR-Gankyrin axis is involved in development of pediatric liver cancer. Carcinogenesis. 2017;38:738-747 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 3b
  • western blot; human; 1:1000; loading ...; fig 3a
Liu X, Zhao B, Sun L, Bhuripanyo K, Wang Y, Bi Y, et al. Orthogonal ubiquitin transfer identifies ubiquitination substrates under differential control by the two ubiquitin activating enzymes. Nat Commun. 2017;8:14286 pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; fig 3e
  • western blot; mouse; 1:1000; loading ...; fig 2c
Wu X, Wu X, Ma Y, Shao F, Tan Y, Tan T, et al. CUG-binding protein 1 regulates HSC activation and liver fibrogenesis. Nat Commun. 2016;7:13498 pubmed publisher
  • western blot; mouse; loading ...; tbl 1
Liang R, Dong W, Shen X, Peng X, Aceves A, Liu Y. Modeling Myotonic Dystrophy 1 in C2C12 Myoblast Cells. J Vis Exp. 2016;: pubmed publisher
  • western blot; human; loading ...; fig 1a
Le Tonquèze O, Gschloessl B, Legagneux V, Paillard L, Audic Y. Identification of CELF1 RNA targets by CLIP-seq in human HeLa cells. Genom Data. 2016;8:97-103 pubmed publisher
  • immunohistochemistry - frozen section; Xenopus laevis; loading ...; fig 4d
  • western blot; Xenopus laevis; loading ...; fig 4a
  • immunohistochemistry - frozen section; chicken; fig 1a
  • western blot; chicken; fig 2a
Blech Hermoni Y, Sullivan C, Jenkins M, Wessely O, Ladd A. CUG-BP, Elav-like family member 1 (CELF1) is required for normal myofibrillogenesis, morphogenesis, and contractile function in the embryonic heart. Dev Dyn. 2016;245:854-73 pubmed publisher
  • western blot; human; 1:1000; fig 1
Bondy Chorney E, Crawford Parks T, Ravel Chapuis A, Klinck R, Rocheleau L, Pelchat M, et al. Staufen1 Regulates Multiple Alternative Splicing Events either Positively or Negatively in DM1 Indicating Its Role as a Disease Modifier. PLoS Genet. 2016;12:e1005827 pubmed publisher
  • RNA immunoprecipitation; mouse; fig 6
Tang Y, Wang H, Wei B, Guo Y, Gu L, Yang Z, et al. CUG-BP1 regulates RyR1 ASI alternative splicing in skeletal muscle atrophy. Sci Rep. 2015;5:16083 pubmed publisher
  • western blot; human; fig 5
Boulanger G, Cibois M, Viet J, Fostier A, Deschamps S, Pastezeur S, et al. Hypogonadism Associated with Cyp19a1 (Aromatase) Posttranscriptional Upregulation in Celf1 Knockout Mice. Mol Cell Biol. 2015;35:3244-53 pubmed publisher
  • western blot; human; 1:4000; fig 8
Dansithong W, Paul S, Figueroa K, Rinehart M, Wiest S, Pflieger L, et al. Ataxin-2 regulates RGS8 translation in a new BAC-SCA2 transgenic mouse model. PLoS Genet. 2015;11:e1005182 pubmed publisher
  • proximity ligation assay; mouse; 1:100; fig 3
Hausburg M, Doles J, Clement S, Cadwallader A, Hall M, Blackshear P, et al. Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay. elife. 2015;4:e03390 pubmed publisher
Sarfstein R, Nagaraj K, LeRoith D, Werner H. Differential Effects of Insulin and IGF1 Receptors on ERK and AKT Subcellular Distribution in Breast Cancer Cells. Cells. 2019;8: pubmed publisher
Iadevaia V, Wouters M, Kanitz A, Matia Gonz xe1 lez A, Laing E, Gerber A. Tandem RNA isolation reveals functional rearrangement of RNA-binding proteins on CDKN1B/p27Kip1 3'UTRs in cisplatin treated cells. RNA Biol. 2020;17:33-46 pubmed publisher
Dumbovic G, Biayna J, Banús J, Samuelsson J, Roth A, Diederichs S, et al. A novel long non-coding RNA from NBL2 pericentromeric macrosatellite forms a perinucleolar aggregate structure in colon cancer. Nucleic Acids Res. 2018;46:5504-5524 pubmed publisher
Ramanathan M, Majzoub K, Rao D, Neela P, Zarnegar B, Mondal S, et al. RNA-protein interaction detection in living cells. Nat Methods. 2018;15:207-212 pubmed publisher
Cho D, Doles J. Single cell transcriptome analysis of muscle satellite cells reveals widespread transcriptional heterogeneity. Gene. 2017;636:54-63 pubmed publisher
Lewis K, Valanejad L, Cast A, Wright M, Wei C, Iakova P, et al. RNA Binding Protein CUGBP1 Inhibits Liver Cancer in a Phosphorylation-Dependent Manner. Mol Cell Biol. 2017;37: pubmed publisher
Sarfstein R, Pasmanik Chor M, Yeheskel A, Edry L, Shomron N, Warman N, et al. Insulin-like growth factor-I receptor (IGF-IR) translocates to nucleus and autoregulates IGF-IR gene expression in breast cancer cells. J Biol Chem. 2012;287:2766-76 pubmed publisher
Lee J, Lee J, Wilusz J, Tian B, Wilusz C. Systematic analysis of cis-elements in unstable mRNAs demonstrates that CUGBP1 is a key regulator of mRNA decay in muscle cells. PLoS ONE. 2010;5:e11201 pubmed publisher
Le Tonquèze O, Gschloessl B, Namanda Vanderbeken A, Legagneux V, Paillard L, Audic Y. Chromosome wide analysis of CUGBP1 binding sites identifies the tetraspanin CD9 mRNA as a target for CUGBP1-mediated down-regulation. Biochem Biophys Res Commun. 2010;394:884-9 pubmed publisher
Dansithong W, Wolf C, Sarkar P, Paul S, Chiang A, Holt I, et al. Cytoplasmic CUG RNA foci are insufficient to elicit key DM1 features. PLoS ONE. 2008;3:e3968 pubmed publisher
Kawane T, Mimura J, Fujii Kuriyama Y, Horiuchi N. Identification of the promoter region of the parathyroid hormone receptor gene responsible for transcriptional suppression by insulin-like growth factor-I. Arch Biochem Biophys. 2005;439:61-9 pubmed
product information
Catalog Number :
sc-20003
Product Name :
CUG-BP1 (3B1) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
3B1
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
CUG-BP1
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA