Published Application/Species/Sample/Dilution | Reference |
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- immunohistochemistry; mouse; 1:1000; loading ...; fig e2b
| Kiryu Seo S, Matsushita R, Tashiro Y, Yoshimura T, Iguchi Y, Katsuno M, et al. Impaired disassembly of the axon initial segment restricts mitochondrial entry into damaged axons. EMBO J. 2022;41:e110486 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; loading ...; fig 1g
| Reibring C, El Shahawy M, Hallberg K, Harfe B, Linde A, Gritli Linde A. Loss of BMP2 and BMP4 Signaling in the Dental Epithelium Causes Defective Enamel Maturation and Aberrant Development of Ameloblasts. Int J Mol Sci. 2022;23: pubmed publisher
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- immunohistochemistry; mouse; 1:2000; loading ...; fig 4a
| Bassal M, Liu J, Jankowiak W, Saftig P, Bartsch U. Rapid and Progressive Loss of Multiple Retinal Cell Types in Cathepsin D-Deficient Mice-An Animal Model of CLN10 Disease. Cells. 2021;10: pubmed publisher
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- immunocytochemistry; mouse; 1:200; loading ...; fig s16a
| Mousavy Gharavy S, Owen B, Millership S, Chabosseau P, Pizza G, Martinez Sanchez A, et al. Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis. Diabetologia. 2021;64:850-864 pubmed publisher
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- immunocytochemistry; mouse; 1:200; loading ...; fig 1b
| Escamilla Ayala A, Sannerud R, Mondin M, Poersch K, Vermeire W, Paparelli L, et al. Super-resolution microscopy reveals majorly mono- and dimeric presenilin1/γ-secretase at the cell surface. elife. 2020;9: pubmed publisher
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- immunocytochemistry; rhesus macaque; 1:50; loading ...; fig 7a
| Du T, Zhu G, Chen Y, Shi L, Liu D, Liu Y, et al. Anterior thalamic nucleus stimulation protects hippocampal neurons by activating autophagy in epileptic monkeys. Aging (Albany NY). 2020;12:6324-6339 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 2f
| Jaynes J, Sable R, Ronzetti M, Bautista W, Knotts Z, Abisoye Ogunniyan A, et al. Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses. Sci Transl Med. 2020;12: pubmed publisher
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- immunohistochemistry - free floating section; mouse; 1:10; loading ...; fig s8c
| Zhang P, Kishimoto Y, Grammatikakis I, Gottimukkala K, Cutler R, Zhang S, et al. Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model. Nat Neurosci. 2019;22:719-728 pubmed publisher
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- immunohistochemistry - frozen section; mouse; loading ...; fig 2b
| Cabrera J, Manivanh R, North B, Leib D. The ESCRT-Related ATPase Vps4 Is Modulated by Interferon during Herpes Simplex Virus 1 Infection. MBio. 2019;10: pubmed publisher
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- immunohistochemistry; rat; 1:400; loading ...; fig s1
| Alissafi T, Hatzioannou A, Mintzas K, Barouni R, Banos A, Sormendi S, et al. Autophagy orchestrates the regulatory program of tumor-associated myeloid-derived suppressor cells. J Clin Invest. 2018;128:3840-3852 pubmed publisher
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- immunocytochemistry; mouse; loading ...; fig 3e
| Iseka F, Goetz B, Mushtaq I, An W, Cypher L, Bielecki T, et al. Role of the EHD Family of Endocytic Recycling Regulators for TCR Recycling and T Cell Function. J Immunol. 2018;200:483-499 pubmed publisher
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- immunocytochemistry; mouse; loading ...; fig 1g
| Bartolomeo R, Cinque L, De Leonibus C, Forrester A, Salzano A, Monfregola J, et al. mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy. J Clin Invest. 2017;127:3717-3729 pubmed publisher
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- immunocytochemistry; human; 1:50; fig 3g
| Olivares O, Mayers J, Gouirand V, Torrence M, Gicquel T, Borge L, et al. Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions. Nat Commun. 2017;8:16031 pubmed publisher
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- immunohistochemistry; mouse; 1:400; loading ...; fig 1c
| Alissafi T, Banos A, Boon L, Sparwasser T, Ghigo A, Wing K, et al. Tregs restrain dendritic cell autophagy to ameliorate autoimmunity. J Clin Invest. 2017;127:2789-2804 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 3b
| Allison R, Edgar J, Pearson G, Rizo T, Newton T, Günther S, et al. Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia. J Cell Biol. 2017;216:1337-1355 pubmed publisher
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- immunocytochemistry; mouse; 1:500; loading ...; fig 4a
| Bagh M, Peng S, Chandra G, Zhang Z, Singh S, Pattabiraman N, et al. Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model. Nat Commun. 2017;8:14612 pubmed publisher
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- immunohistochemistry; mouse; 1:50; loading ...; fig 3a
| Pi H, Li M, Tian L, Yang Z, Yu Z, Zhou Z. Enhancing lysosomal biogenesis and autophagic flux by activating the transcription factor EB protects against cadmium-induced neurotoxicity. Sci Rep. 2017;7:43466 pubmed publisher
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- western blot; mouse; 1:50
| Lee H, Noh H, Mun J, Gu C, Sever S, Park S. Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis. Nat Commun. 2016;7:12799 pubmed publisher
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- immunohistochemistry; mouse; loading ...; fig s2c
| Safaiyan S, Kannaiyan N, Snaidero N, Brioschi S, Biber K, Yona S, et al. Age-related myelin degradation burdens the clearance function of microglia during aging. Nat Neurosci. 2016;19:995-8 pubmed publisher
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- western blot; mouse; fig 3
| Pastore N, Brady O, Diab H, Martina J, Sun L, Huynh T, et al. TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages. Autophagy. 2016;12:1240-58 pubmed publisher
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- immunocytochemistry; mouse; loading ...; fig 3c
| O Rourke J, Bogdanik L, Yáñez A, Lall D, Wolf A, Muhammad A, et al. C9orf72 is required for proper macrophage and microglial function in mice. Science. 2016;351:1324-9 pubmed publisher
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- immunocytochemistry; mouse; fig 3
| Katzenell S, Leib D. Herpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory Neurons. J Virol. 2016;90:4706-4719 pubmed publisher
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- western blot; mouse; loading ...; fig s5b
| Liu Y, Takahashi Y, Desai N, Zhang J, Serfass J, Shi Y, et al. Bif-1 deficiency impairs lipid homeostasis and causes obesity accompanied by insulin resistance. Sci Rep. 2016;6:20453 pubmed publisher
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- immunohistochemistry; human
| GarcÃa Prat L, MartÃnez Vicente M, Perdiguero E, Ortet L, RodrÃguez Ubreva J, Rebollo E, et al. Autophagy maintains stemness by preventing senescence. Nature. 2016;529:37-42 pubmed publisher
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- immunocytochemistry; mouse; fig 4
| He J, Johnson J, Monfregola J, Ramadass M, Pestonjamasp K, Napolitano G, et al. Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses. Mol Biol Cell. 2016;27:572-87 pubmed publisher
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- immunocytochemistry; mouse; fig 1b
| Chesarino N, McMichael T, Yount J. E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3. PLoS Pathog. 2015;11:e1005095 pubmed publisher
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| Balaji K, French C, Miller J, Colicelli J. The RAB5-GEF function of RIN1 regulates multiple steps during Listeria monocytogenes infection. Traffic. 2014;15:1206-18 pubmed publisher
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- immunohistochemistry; mouse; loading ...; fig 6c
| Reibring C, El Shahawy M, Hallberg K, Kannius Janson M, Nilsson J, Parkkila S, et al. Expression patterns and subcellular localization of carbonic anhydrases are developmentally regulated during tooth formation. PLoS ONE. 2014;9:e96007 pubmed publisher
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| Krogsaeter E, McKetney J, Marquez A, Cakir Z, Stevenson E, Jang G, et al. Lysosomal proteomics reveals mechanisms of neuronal apoE4associated lysosomal dysfunction. bioRxiv. 2023;: pubmed publisher
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| Li M, Wu X, Jing W, Hou W, Hu S, Yan W. Inosine enhances tumor mitochondrial respiration by inducing Rag GTPases and nascent protein synthesis under nutrient starvation. Cell Death Dis. 2023;14:492 pubmed publisher
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| Breitmeyer R, Vogel S, Heider J, Hartmann S, W xfc st R, Keller A, et al. Regulation of synaptic connectivity in schizophrenia spectrum by mutual neuron-microglia interaction. Commun Biol. 2023;6:472 pubmed publisher
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| Chen J, Zou L, Lu G, Grinchuk O, Fang L, Ong D, et al. PFKP alleviates glucose starvation-induced metabolic stress in lung cancer cells via AMPK-ACC2 dependent fatty acid oxidation. Cell Discov. 2022;8:52 pubmed publisher
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| Barral D, Staiano L, Guimas Almeida C, Cutler D, Eden E, Futter C, et al. Current methods to analyze lysosome morphology, positioning, motility and function. Traffic. 2022;23:238-269 pubmed publisher
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| Rahman F, Johnson J, Zhang J, He J, Pestonjamasp K, Cherqui S, et al. DYNC1LI2 regulates localization of the chaperone-mediated autophagy receptor LAMP2A and improves cellular homeostasis in cystinosis. Autophagy. 2021;:1-19 pubmed publisher
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| Wang H, Qi W, Zou C, Xie Z, Zhang M, Naito M, et al. NEK1-mediated retromer trafficking promotes blood-brain barrier integrity by regulating glucose metabolism and RIPK1 activation. Nat Commun. 2021;12:4826 pubmed publisher
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| Silwal P, Kim J, Jeon S, Lee J, Kim Y, Kim Y, et al. Mitofusin-2 boosts innate immunity through the maintenance of aerobic glycolysis and activation of xenophagy in mice. Commun Biol. 2021;4:548 pubmed publisher
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| Ou P, Wen L, Liu X, HUANG J, Huang X, Su C, et al. Thioesterase PPT1 balances viral resistance and efficient T cell crosspriming in dendritic cells. J Exp Med. 2019;: pubmed publisher
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| Tamura N, Kageyama S, Komatsu M, Waguri S. Hyperosmotic stress induces unconventional autophagy independent of the Ulk1 complex. Mol Cell Biol. 2019;: pubmed publisher
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| Zhang J, He J, Johnson J, Napolitano G, Ramadass M, Rahman F, et al. Cross-regulation of defective endolysosome trafficking and enhanced autophagy through TFEB in UNC13D deficiency. Autophagy. 2019;:1-19 pubmed publisher
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| Wang R, Tan J, Chen T, Han H, Tian R, Tan Y, et al. ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome-lysosome fusion. J Cell Biol. 2019;218:267-284 pubmed publisher
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| Plesch E, Chen C, Butz E, Scotto Rosato A, Krogsaeter E, Yinan H, et al. Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells. elife. 2018;7: pubmed publisher
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| Abdelkarim H, Marshall M, Scesa G, Smith R, Rue E, Marshall J, et al. ?-Synuclein interacts directly but reversibly with psychosine: implications for ?-synucleinopathies. Sci Rep. 2018;8:12462 pubmed publisher
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| Zhang Y, Burberry A, Wang J, Sandoe J, Ghosh S, Udeshi N, et al. The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis. Genes Dev. 2018;32:929-943 pubmed publisher
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| Lotfi P, Tse D, di Ronza A, Seymour M, Martano G, Cooper J, et al. Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency. Autophagy. 2018;14:1419-1434 pubmed publisher
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| Zhang J, Johnson J, He J, Napolitano G, Ramadass M, Rocca C, et al. Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A. J Biol Chem. 2017;292:10328-10346 pubmed publisher
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| Rojansky R, Cha M, Chan D. Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1. elife. 2016;5: pubmed publisher
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| Marcó S, Pujol A, Roca C, Motas S, Ribera A, Garcia M, et al. Progressive neurologic and somatic disease in a novel mouse model of human mucopolysaccharidosis type IIIC. Dis Model Mech. 2016;9:999-1013 pubmed publisher
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| Marquer C, Tian H, Yi J, Bastien J, Dall Armi C, Yang Klingler Y, et al. Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism. Nat Commun. 2016;7:11919 pubmed publisher
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| Johnson J, He J, Ramadass M, Pestonjamasp K, Kiosses W, Zhang J, et al. Munc13-4 Is a Rab11-binding Protein That Regulates Rab11-positive Vesicle Trafficking and Docking at the Plasma Membrane. J Biol Chem. 2016;291:3423-38 pubmed publisher
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| Marbiah M, Harvey A, West B, Louzolo A, Banerjee P, Alden J, et al. Identification of a gene regulatory network associated with prion replication. EMBO J. 2014;33:1527-47 pubmed publisher
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| Getty A, Kovács A, Lengyel Nelson T, Cardillo A, Hof C, Chan C, et al. Osmotic stress changes the expression and subcellular localization of the Batten disease protein CLN3. PLoS ONE. 2013;8:e66203 pubmed publisher
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| Doursout M, Schurdell M, Young L, Osuagwu U, Hook D, Poindexter B, et al. Inflammatory cells and cytokines in the olfactory bulb of a rat model of neuroinflammation; insights into neurodegeneration?. J Interferon Cytokine Res. 2013;33:376-83 pubmed publisher
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| Hughes J, Frago S, Bühnemann C, Carter E, Hassan A. Maternal transmission of a humanised Igf2r allele results in an Igf2 dependent hypomorphic and non-viable growth phenotype. PLoS ONE. 2013;8:e57270 pubmed publisher
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| Ohmi K, Zhao H, Neufeld E. Defects in the medial entorhinal cortex and dentate gyrus in the mouse model of Sanfilippo syndrome type B. PLoS ONE. 2011;6:e27461 pubmed publisher
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| Cao Y, Staropoli J, Biswas S, Espinola J, MacDonald M, Lee J, et al. Distinct early molecular responses to mutations causing vLINCL and JNCL presage ATP synthase subunit C accumulation in cerebellar cells. PLoS ONE. 2011;6:e17118 pubmed publisher
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| Eliyahu E, Shtraizent N, Martinuzzi K, Barritt J, He X, Wei H, et al. Acid ceramidase improves the quality of oocytes and embryos and the outcome of in vitro fertilization. FASEB J. 2010;24:1229-38 pubmed publisher
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| Korbelik M, Cooper P. Potentiation of photodynamic therapy of cancer by complement: the effect of gamma-inulin. Br J Cancer. 2007;96:67-72 pubmed
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| Leblanc P, Alais S, Porto Carreiro I, Lehmann S, Grassi J, Raposo G, et al. Retrovirus infection strongly enhances scrapie infectivity release in cell culture. EMBO J. 2006;25:2674-85 pubmed
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