product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
LAMP-2 (M3/84) Antibody
catalog :
sc-19991
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
M3/84
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, western blot knockout validation
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 1
  • western blot knockout validation; human; fig 3
Aizawa S, Fujiwara Y, Contu V, Hase K, Takahashi M, Kikuchi H, et al. Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes. Autophagy. 2016;12:565-78 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 4a
Varona S, Puertas L, Galán M, Orriols M, Cañes L, Aguiló S, et al. Rolipram Prevents the Formation of Abdominal Aortic Aneurysm (AAA) in Mice: PDE4B as a Target in AAA. Antioxidants (Basel). 2021;10: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2a
Clemente C, Rius C, Alonso Herranz L, Martín Alonso M, Pollán A, Camafeita E, et al. MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis. Nat Commun. 2018;9:910 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig st10
Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s6c
Fuster J, MacLauchlan S, Zuriaga M, Polackal M, Ostriker A, Chakraborty R, et al. Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice. Science. 2017;355:842-847 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:250; fig 4
Galán M, Varona S, Orriols M, Rodríguez J, Aguiló S, Dilmé J, et al. Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: therapeutic potential of HDAC inhibitors. Dis Model Mech. 2016;9:541-52 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Ampem G, Azegrouz H, Bacsadi Ã, Balogh L, Schmidt S, Thuróczy J, et al. Adipose tissue macrophages in non-rodent mammals: a comparative study. Cell Tissue Res. 2016;363:461-78 pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; fig 1f
  • immunohistochemistry; mouse; 1:200; loading ...; fig 2c
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 8a
Singh N, Kotla S, Dyukova E, Traylor J, Orr A, Chernoff J, et al. Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice. Nat Commun. 2015;6:7450 pubmed publisher
  • western blot; mouse; 1:200; fig 6
Kessinger C, Kim J, Henke P, Thompson B, McCarthy J, Hara T, et al. Statins improve the resolution of established murine venous thrombosis: reductions in thrombus burden and vein wall scarring. PLoS ONE. 2015;10:e0116621 pubmed publisher
Liu W, Ye C, Cheng Q, Zhang X, Yao L, Li Q, et al. Macrophage Raptor Deficiency-Induced Lysosome Dysfunction Exacerbates Nonalcoholic Steatohepatitis. Cell Mol Gastroenterol Hepatol. 2019;7:211-231 pubmed publisher
Raghavan S, Singh N, Mani A, Rao G. Protease-activated receptor 1 inhibits cholesterol efflux and promotes atherogenesis via cullin 3-mediated degradation of the ABCA1 transporter. J Biol Chem. 2018;293:10574-10589 pubmed publisher
Aizawa S, Contu V, Fujiwara Y, Hase K, Kikuchi H, Kabuta C, et al. Lysosomal membrane protein SIDT2 mediates the direct uptake of DNA by lysosomes. Autophagy. 2017;13:218-222 pubmed publisher
Kotla S, Singh N, Heckle M, Tigyi G, Rao G. The transcription factor CREB enhances interleukin-17A production and inflammation in a mouse model of atherosclerosis. Sci Signal. 2013;6:ra83 pubmed publisher
Meisner J, Song J, Price R. Arteriolar and venular remodeling are differentially regulated by bone marrow-derived cell-specific CX3CR1 and CCR2 expression. PLoS ONE. 2012;7:e46312 pubmed publisher
Fuster J, Molina Sánchez P, Jovaní D, Vinue A, Serrano M, Andres V. Increased gene dosage of the Ink4/Arf locus does not attenuate atherosclerosis development in hypercholesterolaemic mice. Atherosclerosis. 2012;221:98-105 pubmed publisher
Bektas M, Allende M, Lee B, Chen W, Amar M, Remaley A, et al. Sphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liver. J Biol Chem. 2010;285:10880-9 pubmed publisher
Dupasquier C, Dibrov E, Kneesh A, Cheung P, Lee K, Alexander H, et al. Dietary flaxseed inhibits atherosclerosis in the LDL receptor-deficient mouse in part through antiproliferative and anti-inflammatory actions. Am J Physiol Heart Circ Physiol. 2007;293:H2394-402 pubmed
Gonzalez Navarro H, Vila Caballer M, Pastor M, Vinue A, White M, Burks D, et al. Plasma insulin levels predict the development of atherosclerosis when IRS2 deficiency is combined with severe hypercholesterolemia in apolipoprotein E-null mice. Front Biosci. 2007;12:2291-8 pubmed
Sanz González S, Melero Fernández de Mera R, Malek N, Andres V. Atheroma development in apolipoprotein E-null mice is not regulated by phosphorylation of p27(Kip1) on threonine 187. J Cell Biochem. 2006;97:735-43 pubmed
Castro C, Campistol J, Barettino D, Andres V. Transcriptional profiling of early onset diet-induced atherosclerosis in apolipoprotein E-deficient mice. Front Biosci. 2005;10:1932-45 pubmed
Kanda T, Hayashi K, Wakino S, Homma K, Yoshioka K, Hasegawa K, et al. Role of Rho-kinase and p27 in angiotensin II-induced vascular injury. Hypertension. 2005;45:724-9 pubmed
product information
Catalog Number :
sc-19991
Product Name :
LAMP-2 (M3/84) Antibody
Product Type :
Monoclonal
Host Species :
rat
Clonality :
monoclonal
Clone Name :
M3/84
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
LAMP-2
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), FCM
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA