product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
HCAM (IM7) Antibody
catalog :
sc-18849
quantity :
200 µg/ml
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
IM7
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 16
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig 5e
Han Y, Feng H, Sun J, Liang X, Wang Z, Xing W, et al. Lkb1 deletion in periosteal mesenchymal progenitors induces osteogenic tumors through mTORC1 activation. J Clin Invest. 2019;130: pubmed publisher
  • flow cytometry; mouse; fig 2
Liang Y, Hu J, Li J, Liu Y, Yu J, Zhuang X, et al. Epigenetic Activation of TWIST1 by MTDH Promotes Cancer Stem-like Cell Traits in Breast Cancer. Cancer Res. 2015;75:3672-80 pubmed publisher
  • immunocytochemistry; human; fig 3
  • western blot; human; fig 3
Li L, Qi L, Liang Z, Song W, Liu Y, Wang Y, et al. Transforming growth factor-β1 induces EMT by the transactivation of epidermal growth factor signaling through HA/CD44 in lung and breast cancer cells. Int J Mol Med. 2015;36:113-22 pubmed publisher
  • flow cytometry; human; loading ...; fig 3a
Ghotra V, He S, van der Horst G, Nijhoff S, de Bont H, Lekkerkerker A, et al. SYK is a candidate kinase target for the treatment of advanced prostate cancer. Cancer Res. 2015;75:230-40 pubmed publisher
  • immunocytochemistry; mouse; 1:50
Yuan F, Li X, Lin J, Schwabe C, Bullesbach E, Rao C, et al. The role of RXFP2 in mediating androgen-induced inguinoscrotal testis descent in LH receptor knockout mice. Reproduction. 2010;139:759-69 pubmed publisher
Boers R, Boers J, Tan B, van Leeuwen M, Wassenaar E, Sanchez E, et al. Retrospective analysis of enhancer activity and transcriptome history. Nat Biotechnol. 2023;: pubmed publisher
Fu D, Wang L, Chouairi F, Rose I, Abetov D, Miller A, et al. Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5-CD44+ cells. Nat Commun. 2020;11:84 pubmed publisher
Zhang H, Brown R, Wei Y, Zhao P, Liu S, Liu X, et al. CD44 splice isoform switching determines breast cancer stem cell state. Genes Dev. 2019;33:166-179 pubmed publisher
Chow H, Dong B, Valencia C, Zeng C, Koch J, Prudnikova T, et al. Group I Paks are essential for epithelial- mesenchymal transition in an Apc-driven model of colorectal cancer. Nat Commun. 2018;9:3473 pubmed publisher
Decker R, Um H, Dyment N, Cottingham N, Usami Y, Enomoto Iwamoto M, et al. Cell origin, volume and arrangement are drivers of articular cartilage formation, morphogenesis and response to injury in mouse limbs. Dev Biol. 2017;426:56-68 pubmed publisher
Wang P, Weng C, Hou Y, Jian S, Fang K, Hou M, et al. Activation of VCAM-1 and its associated molecule CD44 leads to increased malignant potential of breast cancer cells. Int J Mol Sci. 2014;15:3560-79 pubmed publisher
Milovancev M, Hilgart Martiszus I, McNamara M, Goodall C, Seguin B, Bracha S, et al. Comparative analysis of the surface exposed proteome of two canine osteosarcoma cell lines and normal canine osteoblasts. BMC Vet Res. 2013;9:116 pubmed publisher
Su H, Weng C, Hsiao P, Chen L, Kuo T, Chen Y, et al. Stem cell marker nestin is critical for TGF-?1-mediated tumor progression in pancreatic cancer. Mol Cancer Res. 2013;11:768-79 pubmed publisher
Kurth T, Dell accio F, Crouch V, Augello A, Sharpe P, De Bari C. Functional mesenchymal stem cell niches in adult mouse knee joint synovium in vivo. Arthritis Rheum. 2011;63:1289-300 pubmed publisher
Tolg C, Hamilton S, Nakrieko K, Kooshesh F, Walton P, McCarthy J, et al. Rhamm-/- fibroblasts are defective in CD44-mediated ERK1,2 motogenic signaling, leading to defective skin wound repair. J Cell Biol. 2006;175:1017-28 pubmed
Hayer S, Steiner G, Görtz B, Reiter E, Tohidast Akrad M, Amling M, et al. CD44 is a determinant of inflammatory bone loss. J Exp Med. 2005;201:903-14 pubmed
product information
Product Name :
HCAM (IM7) Antibody
Gene Name :
CD44
Size :
200 µg/ml
Catalog Number :
sc-18849
Type :
Monoclonal
Host :
rat monoclonal
Antigen :
HCAM
reactive species  :
m, r, h, canine, feline, equine
Application :
WB, IP, IF, IHC(P), FCM
Epitope :
FL (m)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA