product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
FRS2 (A-5) Antibody
catalog :
sc-17841
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A-5
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human
Czaplinska D, Turczyk L, Grudowska A, Mieszkowska M, Lipinska A, Skladanowski A, et al. Phosphorylation of RSK2 at Tyr529 by FGFR2-p38 enhances human mammary epithelial cells migration. Biochim Biophys Acta. 2014;1843:2461-70 pubmed publisher
Boichuk S, Dunaev P, Skripova V, Galembikova A, Bikinieva F, Shagimardanova E, et al. Unraveling the Mechanisms of Sensitivity to Anti-FGF Therapies in Imatinib-Resistant Gastrointestinal Stromal Tumors (GIST) Lacking Secondary KIT Mutations. Cancers (Basel). 2023;15: pubmed publisher
Zarczynska I, Gorska Arcisz M, Cortez A, Kujawa K, Wilk A, Skladanowski A, et al. p38 Mediates Resistance to FGFR Inhibition in Non-Small Cell Lung Cancer. Cells. 2021;10: pubmed publisher
Kitowska K, Gorska Arcisz M, Antoun D, Zarczynska I, Czaplinska D, Szczepaniak A, et al. MET-Pyk2 Axis Mediates Acquired Resistance to FGFR Inhibition in Cancer Cells. Front Oncol. 2021;11:633410 pubmed publisher
Valencia T, Joseph A, Kachroo N, Darby S, Meakin S, Gnanapragasam V. Role and expression of FRS2 and FRS3 in prostate cancer. BMC Cancer. 2011;11:484 pubmed publisher
Dutt A, Ramos A, Hammerman P, Mermel C, Cho J, Sharifnia T, et al. Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer. PLoS ONE. 2011;6:e20351 pubmed publisher
Dutt A, Salvesen H, Chen T, Ramos A, Onofrio R, Hatton C, et al. Drug-sensitive FGFR2 mutations in endometrial carcinoma. Proc Natl Acad Sci U S A. 2008;105:8713-7 pubmed publisher
product information
Product Name :
FRS2 (A-5) Antibody
Gene Name :
FRS2
Size :
200 µg/ml
Catalog Number :
sc-17841
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
FRS2
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
258-348 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA