product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
ERCC1 (D-10) Antibody
catalog :
sc-17809
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D-10
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, reverse phase protein lysate microarray, other
citations: 22
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1a
Sabatella M, Theil A, Ribeiro Silva C, Slyskova J, Thijssen K, Voskamp C, et al. Repair protein persistence at DNA lesions characterizes XPF defect with Cockayne syndrome features. Nucleic Acids Res. 2018;46:9563-9577 pubmed publisher
  • western blot; human; 1:1000; fig 3ai
Galanos P, Pappas G, Polyzos A, Kotsinas A, Svolaki I, Giakoumakis N, et al. Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability. Genome Biol. 2018;19:37 pubmed publisher
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • reverse phase protein lysate microarray; human; loading ...; fig st6
Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
. Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 4
van Cuijk L, van Belle G, Turkyilmaz Y, Poulsen S, Janssens R, Theil A, et al. SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair. Nat Commun. 2015;6:7499 pubmed publisher
  • immunocytochemistry; human; 1:150
Liu Y, Jiang Y, Wang B, Hao J, Shang L, Zhang T, et al. A panel of protein markers for the early detection of lung cancer with bronchial brushing specimens. Cancer Cytopathol. 2014;122:833-41 pubmed publisher
Marcozzi S, Rossi V, Salvatore G, Di Rella F, De Felici M, Klinger F. Distinct effects of epirubicin, cisplatin and cyclophosphamide on ovarian somatic cells of prepuberal ovaries. Aging (Albany NY). 2019;11:10532-10556 pubmed publisher
Zhang H, Chen Z, Ye Y, Ye Z, Cao D, Xiong Y, et al. SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair. Nucleic Acids Res. 2019;47:10181-10201 pubmed publisher
MacGregor T, Carter R, Gillies R, Findlay J, Kartsonaki C, Castro Giner F, et al. Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma. Sci Rep. 2018;8:7265 pubmed publisher
Tomita T, Ieguchi K, Coin F, Coin F, Kato Y, Kikuchi H, et al. ZFC3H1, a zinc finger protein, modulates IL-8 transcription by binding with celastramycin A, a potential immune suppressor. PLoS ONE. 2014;9:e108957 pubmed publisher
Mohni K, Kavanaugh G, Cortez D. ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency. Cancer Res. 2014;74:2835-45 pubmed publisher
Hatch S, Swift L, Caporali S, Carter R, Hill E, Macgregor T, et al. XPF protein levels determine sensitivity of malignant melanoma cells to oxaliplatin chemotherapy: suitability as a biomarker for patient selection. Int J Cancer. 2014;134:1495-503 pubmed publisher
Renaud E, Rosselli F. FANC pathway promotes UV-induced stalled replication forks recovery by acting both upstream and downstream Pol? and Rev1. PLoS ONE. 2013;8:e53693 pubmed publisher
Song L, Robson T, Doig T, Brenn T, Mathers M, Brown E, et al. DNA repair and replication proteins as prognostic markers in melanoma. Histopathology. 2013;62:343-50 pubmed publisher
Das M, Riess J, Frankel P, Schwartz E, Bennis R, Hsieh H, et al. ERCC1 expression in circulating tumor cells (CTCs) using a novel detection platform correlates with progression-free survival (PFS) in patients with metastatic non-small-cell lung cancer (NSCLC) receiving platinum chemotherapy. Lung Cancer. 2012;77:421-6 pubmed publisher
Rageul J, Frémin C, Ezan F, Baffet G, Langouet S. The knock-down of ERCC1 but not of XPF causes multinucleation. DNA Repair (Amst). 2011;10:978-90 pubmed publisher
Somlo G, Lau S, Frankel P, Hsieh H, Liu X, Yang L, et al. Multiple biomarker expression on circulating tumor cells in comparison to tumor tissues from primary and metastatic sites in patients with locally advanced/inflammatory, and stage IV breast cancer, using a novel detection technology. Breast Cancer Res Treat. 2011;128:155-63 pubmed publisher
Zhang Y, Regairaz M, Seiler J, Agama K, Doroshow J, Pommier Y. Poly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells. Nucleic Acids Res. 2011;39:3607-20 pubmed publisher
Selfridge J, Song L, Brownstein D, Melton D. Mice with DNA repair gene Ercc1 deficiency in a neural crest lineage are a model for late-onset Hirschsprung disease. DNA Repair (Amst). 2010;9:653-60 pubmed publisher
Gonzalez Suarez I, Redwood A, Perkins S, Vermolen B, Lichtensztejin D, Grotsky D, et al. Novel roles for A-type lamins in telomere biology and the DNA damage response pathway. EMBO J. 2009;28:2414-27 pubmed publisher
Chen H, Shao C, Chen F, Kwan A, Chen Z. Role of ERCC1 promoter hypermethylation in drug resistance to cisplatin in human gliomas. Int J Cancer. 2010;126:1944-1954 pubmed publisher
product information
Product Name :
ERCC1 (D-10) Antibody
Gene Name :
ERCC1
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-17809
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
ERCC1
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
1-297 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA