product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Ku-70 (E-5) Antibody
catalog :
sc-17789
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
E-5
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 22
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig 3b
Craxton A, Munnur D, Jukes Jones R, Skalka G, Langlais C, Cain K, et al. PAXX and its paralogs synergistically direct DNA polymerase λ activity in DNA repair. Nat Commun. 2018;9:3877 pubmed publisher
  • western blot; human; fig 1
Laurette P, Strub T, Koludrovic D, Keime C, Le Gras S, Seberg H, et al. Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells. elife. 2015;4: pubmed publisher
  • western blot; human
Dutta B, Yan R, Lim S, Tam J, Sze S. Quantitative profiling of chromatome dynamics reveals a novel role for HP1BP3 in hypoxia-induced oncogenesis. Mol Cell Proteomics. 2014;13:3236-49 pubmed publisher
Takeda Y, Matoba K, Kawanami D, Nagai Y, Akamine T, Ishizawa S, et al. ROCK2 Regulates Monocyte Migration and Cell to Cell Adhesion in Vascular Endothelial Cells. Int J Mol Sci. 2019;20: pubmed publisher
Munnur D, Somers J, Skalka G, Weston R, Jukes Jones R, Bhogadia M, et al. NR4A Nuclear Receptors Target Poly-ADP-Ribosylated DNA-PKcs Protein to Promote DNA Repair. Cell Rep. 2019;26:2028-2036.e6 pubmed publisher
Wang H, Li S, Zhang H, Wang Y, Hao S, Wu X. BLM prevents instability of structure-forming DNA sequences at common fragile sites. PLoS Genet. 2018;14:e1007816 pubmed publisher
Xia Y, Ivanovska I, Zhu K, Smith L, Irianto J, Pfeifer C, et al. Nuclear rupture at sites of high curvature compromises retention of DNA repair factors. J Cell Biol. 2018;217:3796-3808 pubmed publisher
Sabatella M, Theil A, Ribeiro Silva C, Slyskova J, Thijssen K, Voskamp C, et al. Repair protein persistence at DNA lesions characterizes XPF defect with Cockayne syndrome features. Nucleic Acids Res. 2018;46:9563-9577 pubmed publisher
Liu H, Wang X, Feng B, Tang L, Li W, Zheng X, et al. Golgi phosphoprotein 3 (GOLPH3) promotes hepatocellular carcinoma progression by activating mTOR signaling pathway. BMC Cancer. 2018;18:661 pubmed publisher
Lesport E, Ferster A, Biver A, Roch B, Vasquez N, Jabado N, et al. Reduced recruitment of 53BP1 during interstrand crosslink repair is associated with genetically inherited attenuation of mitomycin C sensitivity in a family with Fanconi anemia. Oncotarget. 2018;9:3779-3793 pubmed publisher
Nagaria P, Robert C, Park T, Huo J, Zambidis E, Rassool F. High-Fidelity Reprogrammed Human IPSCs Have a High Efficacy of DNA Repair and Resemble hESCs in Their MYC Transcriptional Signature. Stem Cells Int. 2016;2016:3826249 pubmed publisher
Yao C, Chow J, Yang C, Kuo H, Chang C, Lee H, et al. Chinese Herbal Mixture, Tien-Hsien Liquid, Induces G2/M Cycle Arrest and Radiosensitivity in MCF-7 Human Breast Cancer Cells through Mechanisms Involving DNMT1 and Rad51 Downregulation. Evid Based Complement Alternat Med. 2016;2016:3251046 pubmed publisher
Suman S, Rodriguez O, Winters T, Fornace A, Albanese C, Datta K. Therapeutic and space radiation exposure of mouse brain causes impaired DNA repair response and premature senescence by chronic oxidant production. Aging (Albany NY). 2013;5:607-22 pubmed
Kappei D, Butter F, Benda C, Scheibe M, Draskovic I, Stevense M, et al. HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment. EMBO J. 2013;32:1681-701 pubmed publisher
Singh K, Matsuyama S, Drazba J, Almasan A. Autophagy-dependent senescence in response to DNA damage and chronic apoptotic stress. Autophagy. 2012;8:236-51 pubmed publisher
Di Paola D, Zannis Hadjopoulos M. Comparative analysis of pre-replication complex proteins in transformed and normal cells. J Cell Biochem. 2012;113:1333-47 pubmed publisher
Chen S, Wang H, Ng W, Curran W, Wang Y. Radiosensitizing effects of ectopic miR-101 on non-small-cell lung cancer cells depend on the endogenous miR-101 level. Int J Radiat Oncol Biol Phys. 2011;81:1524-9 pubmed publisher
Ng W, Yan D, Zhang X, Mo Y, Wang Y. Over-expression of miR-100 is responsible for the low-expression of ATM in the human glioma cell line: M059J. DNA Repair (Amst). 2010;9:1170-5 pubmed publisher
Fan J, Li L, Small D, Rassool F. Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy. Blood. 2010;116:5298-305 pubmed publisher
Yan D, Ng W, Zhang X, Wang P, Zhang Z, Mo Y, et al. Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation. PLoS ONE. 2010;5:e11397 pubmed publisher
Samanta A, Li B, Song X, Bembas K, Zhang G, Katsumata M, et al. TGF-beta and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3. Proc Natl Acad Sci U S A. 2008;105:14023-7 pubmed publisher
Lu L, Wang Y. Immunoprecipitation alert: DNA binding proteins directly bind to protein A/G without any antibody as the bridge. Cell Cycle. 2008;7:417-8 pubmed
product information
Product Name :
Ku-70 (E-5) Antibody
Gene Name :
XRCC6
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-17789
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Ku-70
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
302-609 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA