product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
PKC zeta (H-1) Antibody
catalog :
sc-17781
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H-1
reactivity :
human, mouse, rat, chicken
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, other
citations: 27
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig 5l
Qin Y, Chen W, Jiang G, Zhou L, Yang X, Li H, et al. Interfering MSN-NONO complex-activated CREB signaling serves as a therapeutic strategy for triple-negative breast cancer. Sci Adv. 2020;6:eaaw9960 pubmed publisher
  • immunoprecipitation; human; loading ...; fig s3c
  • western blot; human; 1:1000; loading ...; fig s3c
Kennedy S, Jarboui M, Srihari S, Raso C, Bryan K, Dernayka L, et al. Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D. Nat Commun. 2020;11:499 pubmed publisher
  • immunohistochemistry; mouse; 1:50; loading ...; fig s1b
Dumortier J, Le Verge Serandour M, Tortorelli A, Mielke A, de Plater L, Turlier H, et al. Hydraulic fracturing and active coarsening position the lumen of the mouse blastocyst. Science. 2019;365:465-468 pubmed publisher
  • western blot; human; fig 5b
Taoka R, Jinesh G, Xue W, Safe S, Kamat A. CF3DODA-Me induces apoptosis, degrades Sp1, and blocks the transformation phase of the blebbishield emergency program. Apoptosis. 2017;22:719-729 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 2b
Korotkevich E, Niwayama R, Courtois A, Friese S, Berger N, Buchholz F, et al. The Apical Domain Is Required and Sufficient for the First Lineage Segregation in the Mouse Embryo. Dev Cell. 2017;40:235-247.e7 pubmed publisher
  • immunohistochemistry; chicken; fig s3d
Akizu N, García M, Estarás C, Fueyo R, Badosa C, de la Cruz X, et al. EZH2 regulates neuroepithelium structure and neuroblast proliferation by repressing p21. Open Biol. 2016;6:150227 pubmed publisher
  • western blot; mouse
Lin T, Shih Y, Chen S, Lien C, Chang C, Huang T, et al. Running exercise delays neurodegeneration in amygdala and hippocampus of Alzheimer's disease (APP/PS1) transgenic mice. Neurobiol Learn Mem. 2015;118:189-97 pubmed publisher
  • other; human; loading ...; fig 2c
  • western blot; human; loading ...; fig 5b
Hartsink Segers S, Beaudoin J, Luijendijk M, Exalto C, Pieters R, den Boer M. PKC? and PKM? are overexpressed in TCF3-rearranged paediatric acute lymphoblastic leukaemia and are associated with increased thiopurine sensitivity. Leukemia. 2015;29:304-11 pubmed publisher
  • immunohistochemistry; chicken; 1:500; fig 6
  • western blot; chicken; 1:10,000; fig 5
Herrera A, Saade M, Menendez A, Marti E, Pons S. Sustained Wnt/?-catenin signalling causes neuroepithelial aberrations through the accumulation of aPKC at the apical pole. Nat Commun. 2014;5:4168 pubmed publisher
  • immunoprecipitation; human; fig 5
Corr S, Palsson McDermott E, Grishina I, Barry S, Aviello G, Bernard N, et al. MyD88 adaptor-like (Mal) functions in the epithelial barrier and contributes to intestinal integrity via protein kinase C. Mucosal Immunol. 2014;7:57-67 pubmed publisher
Li R, Zhong C, Yu Y, Liu H, Sakurai M, Yu L, et al. Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures. Cell. 2019;179:687-702.e18 pubmed publisher
Schiffhauer E, Ren Y, Iglesias V, Kothari P, Iglesias P, Robinson D. Myosin IIB assembly state determines its mechanosensitive dynamics. J Cell Biol. 2019;218:895-908 pubmed publisher
Hannaford M, Loyer N, Tonelli F, Zoltner M, Januschke J. A chemical-genetics approach to study the role of atypical Protein Kinase C in Drosophila. Development. 2019;146: pubmed publisher
Frum T, Murphy T, Ralston A. HIPPO signaling resolves embryonic cell fate conflicts during establishment of pluripotency in vivo. elife. 2018;7: pubmed publisher
Chen W, Qin Y, Wang D, Zhou L, Liu Y, Chen S, et al. CCL20 triggered by chemotherapy hinders the therapeutic efficacy of breast cancer. PLoS Biol. 2018;16:e2005869 pubmed publisher
Zhu M, Leung C, Shahbazi M, Zernicka Goetz M. Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo. Nat Commun. 2017;8:921 pubmed publisher
Leduc C, Etienne Manneville S. Regulation of microtubule-associated motors drives intermediate filament network polarization. J Cell Biol. 2017;216:1689-1703 pubmed publisher
Maître J, Turlier H, Illukkumbura R, Eismann B, Niwayama R, Nedelec F, et al. Asymmetric division of contractile domains couples cell positioning and fate specification. Nature. 2016;536:344-348 pubmed publisher
Jinesh G, Taoka R, Zhang Q, Gorantla S, Kamat A. Novel PKC-ζ to p47 phox interaction is necessary for transformation from blebbishields. Sci Rep. 2016;6:23965 pubmed publisher
Ma T, Trinh M, Wexler A, Bourbon C, Gatti E, Pierre P, et al. Suppression of eIF2? kinases alleviates Alzheimer's disease-related plasticity and memory deficits. Nat Neurosci. 2013;16:1299-305 pubmed publisher
Melemedjian O, Tillu D, Asiedu M, Mandell E, Moy J, Blute V, et al. BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state. Mol Pain. 2013;9:12 pubmed publisher
Guilgur L, Prudêncio P, Ferreira T, Pimenta Marques A, Martinho R. Drosophila aPKC is required for mitotic spindle orientation during symmetric division of epithelial cells. Development. 2012;139:503-13 pubmed publisher
Alarcon V. Cell polarity regulator PARD6B is essential for trophectoderm formation in the preimplantation mouse embryo. Biol Reprod. 2010;83:347-58 pubmed publisher
Lozovatsky L, Abayasekara N, Piawah S, Walther Z. CASK deletion in intestinal epithelia causes mislocalization of LIN7C and the DLG1/Scrib polarity complex without affecting cell polarity. Mol Biol Cell. 2009;20:4489-99 pubmed publisher
Huang H, Ruan H, Aw M, Hussain A, Guo L, Gao C, et al. Mypt1-mediated spatial positioning of Bmp2-producing cells is essential for liver organogenesis. Development. 2008;135:3209-18 pubmed publisher
Sarkar S, Bananis E, Nath S, Anwer M, Wolkoff A, Murray J. PKCzeta is required for microtubule-based motility of vesicles containing the ntcp transporter. Traffic. 2006;7:1078-91 pubmed
Skjøth I, Issinger O. Profiling of signaling molecules in four different human prostate carcinoma cell lines before and after induction of apoptosis. Int J Oncol. 2006;28:217-29 pubmed
product information
Product Name :
PKC zeta (H-1) Antibody
Gene Name :
PRKCZ
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-17781
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
PKC zeta
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
C-terminal (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA