Published Application/Species/Sample/Dilution | Reference |
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- western blot; human; loading ...; fig 6d
| Zhu H, Su Z, Ning J, Zhou L, Tan L, Sayed S, et al. Transmembrane protein 97 exhibits oncogenic properties via enhancing LRP6-mediated Wnt signaling in breast cancer. Cell Death Dis. 2021;12:912 pubmed publisher
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- western blot; human; 1:500; loading ...; fig 6f
| Hsieh M, Weng C, Lin Y, Wu C, Chen L, Cheng K. Inhibition of β-Catenin Activity Abolishes LKB1 Loss-Driven Pancreatic Cystadenoma in Mice. Int J Mol Sci. 2021;22: pubmed publisher
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- western blot; human; loading ...; fig 10
| Thangaraj K, Balasubramanian B, Park S, Natesan K, Liu W, Manju V. Orientin Induces G0/G1 Cell Cycle Arrest and Mitochondria Mediated Intrinsic Apoptosis in Human Colorectal Carcinoma HT29 Cells. Biomolecules. 2019;9: pubmed publisher
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- western blot; human; loading ...; fig 3d
| Forte I, Indovina P, Iannuzzi C, Cirillo D, Di Marzo D, Barone D, et al. Targeted therapy based on p53 reactivation reduces both glioblastoma cell growth and resistance to temozolomide. Int J Oncol. 2019;54:2189-2199 pubmed publisher
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- western blot; human; loading ...; fig 5f
| Urtishak K, Wang L, Culjkovic Kraljacic B, Davenport J, Porazzi P, Vincent T, et al. Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia. Oncogene. 2019;38:2241-2262 pubmed publisher
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- western blot; human; 1:200; loading ...; fig s3
| Oldrini B, Hsieh W, Erdjument Bromage H, Codega P, Carro M, Curiel García A, et al. EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer. Nat Commun. 2017;8:2035 pubmed publisher
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- western blot; human; loading ...; fig 2b
| Periyasamy M, Singh A, Gemma C, Kranjec C, Farzan R, Leach D, et al. p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells. Nucleic Acids Res. 2017;45:11056-11069 pubmed publisher
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- western blot; human; fig 2b
| Liu Z, Li H, Liu J, Wu M, Chen X, Liu L, et al. Inactivated Wnt signaling in resveratrol-treated epidermal squamous cancer cells and its biological implication. Oncol Lett. 2017;14:2239-2243 pubmed publisher
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- immunohistochemistry; mouse; 1:100; loading ...; fig 6b
| Sgourdou P, Mishra Gorur K, Saotome I, Henagariu O, Tuysuz B, Campos C, et al. Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly. Sci Rep. 2017;7:43708 pubmed publisher
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- immunohistochemistry; human; 1:100; loading ...; fig s3
| Abadía Molina F, Morón Calvente V, Baird S, Shamim F, Martin F, MacKenzie A. Neuronal apoptosis inhibitory protein (NAIP) localizes to the cytokinetic machinery during cell division. Sci Rep. 2017;7:39981 pubmed publisher
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- western blot; human; loading ...; fig 2b
| Park S, Jwa E, Shin S, Ju E, Park I, Pak J, et al. Ibulocydine sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis via calpain-mediated Bax cleavage. Int J Biochem Cell Biol. 2017;83:47-55 pubmed publisher
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- immunohistochemistry; human; 1:50; fig 4
- western blot; human; 1:200
| Fotouhi O, Kjellin H, Larsson C, Hashemi J, Barriuso J, Juhlin C, et al. Proteomics Suggests a Role for APC-Survivin in Response to Somatostatin Analog Treatment of Neuroendocrine Tumors. J Clin Endocrinol Metab. 2016;101:3616-3627 pubmed
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- immunohistochemistry - paraffin section; human; 1:50; fig 1
| Takasaki C, Kobayashi M, Ishibashi H, Akashi T, Okubo K. Expression of hypoxia-inducible factor-1? affects tumor proliferation and antiapoptosis in surgically resected lung cancer. Mol Clin Oncol. 2016;5:295-300 pubmed
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- immunocytochemistry; human; 1:300; fig 1
- western blot; human; fig 2
| Sasai K, Katayama H, Hawke D, Sen S. Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex. PLoS ONE. 2016;11:e0157305 pubmed publisher
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- flow cytometry; human; 1:25; fig 1b
- immunohistochemistry; human; loading ...; fig 1a
- western blot; human; 1:50; fig 1d
| Venkatesan N, Kanwar J, Deepa P, Navaneethakrishnan S, Joseph C, Krishnakumar S. Targeting HSP90/Survivin using a cell permeable structure based peptido-mimetic shepherdin in retinoblastoma. Chem Biol Interact. 2016;252:141-9 pubmed publisher
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- immunohistochemistry - paraffin section; human; fig 5
| Andersson E, Arvidsson Y, Swärd C, Hofving T, Wängberg B, Kristiansson E, et al. Expression profiling of small intestinal neuroendocrine tumors identifies subgroups with clinical relevance, prognostic markers and therapeutic targets. Mod Pathol. 2016;29:616-29 pubmed publisher
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- western blot; human; fig 1
| Li Y, Lu W, Saini S, Moukha Chafiq O, Pathak V, Ananthan S. Identification of quinazoline compounds as novel potent inhibitors of Wnt/?-catenin signaling in colorectal cancer cells. Oncotarget. 2016;7:11263-70 pubmed publisher
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- western blot; human; fig 5
| Vartanian S, Ma T, Lee J, Haverty P, Kirkpatrick D, Yu K, et al. Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis. Mol Cell Proteomics. 2016;15:1220-31 pubmed publisher
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- western blot; human; fig 1
| Ciamporcero E, Shen H, Ramakrishnan S, Yu Ku S, Chintala S, Shen L, et al. YAP activation protects urothelial cell carcinoma from treatment-induced DNA damage. Oncogene. 2016;35:1541-53 pubmed publisher
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- western blot; mouse; loading ...; fig 7d
| Raimondi L, De Luca A, Amodio N, Manno M, Raccosta S, Taverna S, et al. Involvement of multiple myeloma cell-derived exosomes in osteoclast differentiation. Oncotarget. 2015;6:13772-89 pubmed
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- western blot; human; 1:75
| Rogler A, Kendziorra E, Giedl J, Stoehr C, Taubert H, Goebell P, et al. Functional analyses and prognostic significance of SFRP1 expression in bladder cancer. J Cancer Res Clin Oncol. 2015;141:1779-90 pubmed publisher
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| Papanikolaou V, Stefanou N, Dubos S, Papathanasiou I, Palianopoulou M, Valiakou V, et al. Synergy of leptin/STAT3 with HER2 receptor induces tamoxifen resistance in breast cancer cells through regulation of apoptosis-related genes. Cell Oncol (Dordr). 2015;38:155-64 pubmed publisher
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- western blot; mouse; fig 6
| Olayanju A, Copple I, Bryan H, Edge G, Sison R, Wong M, et al. Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2. Free Radic Biol Med. 2015;78:202-12 pubmed publisher
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| Leiphrakpam P, Rajput A, Mathiesen M, Agarwal E, Lazenby A, Are C, et al. Ezrin expression and cell survival regulation in colorectal cancer. Cell Signal. 2014;26:868-79 pubmed publisher
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| Cheng Y, Holloway M, Nguyen K, McCauley D, Landesman Y, Kauffman M, et al. XPO1 (CRM1) inhibition represses STAT3 activation to drive a survivin-dependent oncogenic switch in triple-negative breast cancer. Mol Cancer Ther. 2014;13:675-86 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:50
| Lauxen I, Oliveira M, Rados P, Lingen M, Nor J, Sant Ana Filho M. Immunoprofiling of oral squamous cell carcinomas reveals high p63 and survivin expression. Oral Dis. 2014;20:e76-80 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:50
| Kobayashi M, Huang C, Sonobe M, Kikuchi R, Ishikawa M, Kitamura J, et al. Intratumoral Wnt2B expression affects tumor proliferation and survival in malignant pleural mesothelioma patients. Exp Ther Med. 2012;3:952-958 pubmed
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- western blot; human; 1:100
| Liu D, Kadota K, Ueno M, Nakashima N, Yokomise H, Huang C. Adenoviral vector expressing short hairpin RNA targeting Wnt2B has an effective antitumour activity against Wnt2B2-overexpressing tumours. Eur J Cancer. 2012;48:1208-18 pubmed publisher
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| Zhao B, Song A, Haque R, Lei F, Weiler L, Xiong X, et al. Cooperation between molecular targets of costimulation in promoting T cell persistence and tumor regression. J Immunol. 2009;182:6744-52 pubmed publisher
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| Mohammed Salama M. Role of Napsin A and Survivin Immunohistochemical Expression in Bronchogenic Adenocarcinoma. Asian Pac J Cancer Prev. 2020;21:3345-3348 pubmed publisher
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| Jin L, Zhao K, Xu L, Zhao R, Werle K, Wang Y, et al. LKB1 inactivation leads to centromere defects and genome instability via p53-dependent upregulation of survivin. Aging (Albany NY). 2020;12:14341-14354 pubmed publisher
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| Lee J, Lee H, Ryu K, Kim M, Ko D, Chung K, et al. KCP10043F Represses the Proliferation of Human Non-Small Cell Lung Cancer Cells by Caspase-Mediated Apoptosis via STAT3 Inactivation. J Clin Med. 2020;9: pubmed publisher
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| Carpi S, Fogli S, Giannetti A, Adinolfi B, Tombelli S, Da Pozzo E, et al. Theranostic properties of a survivin-directed molecular beacon in human melanoma cells. PLoS ONE. 2014;9:e114588 pubmed publisher
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| Macha M, Rachagani S, Gupta S, Pai P, Ponnusamy M, Batra S, et al. Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling. Cancer Lett. 2013;341:166-77 pubmed publisher
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| Lazarova D, Chiaro C, Wong T, Drago E, Rainey A, O Malley S, et al. CBP Activity Mediates Effects of the Histone Deacetylase Inhibitor Butyrate on WNT Activity and Apoptosis in Colon Cancer Cells. J Cancer. 2013;4:481-90 pubmed publisher
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| Ly B, Chi H, Yamagishi M, Kano Y, Hara Y, Nakano K, et al. Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells. PLoS ONE. 2013;8:e66378 pubmed publisher
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| Nair S, Marlow F, ABRAMS E, KAPP L, Mullins M, Pelegri F. The chromosomal passenger protein birc5b organizes microfilaments and germ plasm in the zebrafish embryo. PLoS Genet. 2013;9:e1003448 pubmed publisher
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| Cui C, Wang Y, Wang Y, Zhao M, Peng S. Alsterpaullone, a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells through Apoptosis-Inducing Effect. J Anal Methods Chem. 2013;2013:602091 pubmed publisher
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| Al Dhaheri Y, Eid A, Abuqamar S, Attoub S, Khasawneh M, Aiche G, et al. Mitotic arrest and apoptosis in breast cancer cells induced by Origanum majorana extract: upregulation of TNF-? and downregulation of survivin and mutant p53. PLoS ONE. 2013;8:e56649 pubmed publisher
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| Chi H, Ly B, Kano Y, Tojo A, Watanabe T, Sato Y. ETV6-NTRK3 as a therapeutic target of small molecule inhibitor PKC412. Biochem Biophys Res Commun. 2012;429:87-92 pubmed publisher
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| Li J, Wang H, Ma Z, Fan W, Li Y, Han B, et al. TAT-Apoptin induces apoptosis in the human bladder cancer EJ cell line and regulates Bax, Bcl-2, caspase-3 and survivin expression. Exp Ther Med. 2012;3:1033-1038 pubmed
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| Freiburghaus C, Lindmark Månsson H, Paulsson M, Oredsson S. Reduction of ultraviolet light-induced DNA damage in human colon cancer cells treated with a lactoferrin-derived peptide. J Dairy Sci. 2012;95:5552-60 pubmed publisher
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| McCarthy B, Yang L, Ding J, Ren M, King W, Elsalanty M, et al. NF-?B2 mutation targets survival, proliferation and differentiation pathways in the pathogenesis of plasma cell tumors. BMC Cancer. 2012;12:203 pubmed publisher
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| al Yacoub N, Fecker L, Möbs M, Plötz M, Braun F, Sterry W, et al. Apoptosis induction by SAHA in cutaneous T-cell lymphoma cells is related to downregulation of c-FLIP and enhanced TRAIL signaling. J Invest Dermatol. 2012;132:2263-74 pubmed publisher
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| Yuan B, Xian R, Wu X, Jing J, Chen K, Liu G, et al. Endoplasmic reticulum chaperone glucose regulated protein 170-Pokemon complexes elicit a robust antitumor immune response in vivo. Immunobiology. 2012;217:738-42 pubmed publisher
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| Glienke W, Maute L, Wicht J, Bergmann L. The dual PI3K/mTOR inhibitor NVP-BGT226 induces cell cycle arrest and regulates Survivin gene expression in human pancreatic cancer cell lines. Tumour Biol. 2012;33:757-65 pubmed publisher
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| Ekeblad S, Lejonklou M, Stalberg P, Skogseid B. Prognostic relevance of survivin in pancreatic endocrine tumors. World J Surg. 2012;36:1411-8 pubmed publisher
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| Wang Z, Zhao J, Zeng J, Wu K, Chen Y, Wang X, et al. Specific survivin dual fluorescence resonance energy transfer molecular beacons for detection of human bladder cancer cells. Acta Pharmacol Sin. 2011;32:1522-8 pubmed publisher
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| Zhang C, Elkahloun A, Robertson M, Gills J, Tsurutani J, Shih J, et al. Loss of cytoplasmic CDK1 predicts poor survival in human lung cancer and confers chemotherapeutic resistance. PLoS ONE. 2011;6:e23849 pubmed publisher
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| Morrison D, Hogan L, Condos G, Bhatla T, Germino N, Moskowitz N, et al. Endogenous knockdown of survivin improves chemotherapeutic response in ALL models. Leukemia. 2012;26:271-9 pubmed publisher
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| Zhou F, Zhang L, van Laar T, van Dam H, Ten Dijke P. GSK3? inactivation induces apoptosis of leukemia cells by repressing the function of c-Myb. Mol Biol Cell. 2011;22:3533-40 pubmed publisher
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| Nardiello T, Jungbluth A, Mei A, DiLiberto M, Huang X, Dabrowski A, et al. MAGE-A inhibits apoptosis in proliferating myeloma cells through repression of Bax and maintenance of survivin. Clin Cancer Res. 2011;17:4309-19 pubmed publisher
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| Jeong J, Jin C, Park C, Hong S, Kim G, Jeong Y, et al. Induction of apoptosis by cordycepin via reactive oxygen species generation in human leukemia cells. Toxicol In Vitro. 2011;25:817-24 pubmed publisher
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| Huang J, Wang F, Okuka M, Liu N, Ji G, Ye X, et al. Association of telomere length with authentic pluripotency of ES/iPS cells. Cell Res. 2011;21:779-92 pubmed publisher
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| Liu F, Hu X, Zimmerman M, Waller J, Wu P, Hayes Jordan A, et al. TNF? cooperates with IFN-? to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis. PLoS ONE. 2011;6:e16241 pubmed publisher
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| Glienke W, Hausmann E, Bergmann L. Downregulation of STAT3 signaling induces apoptosis but also promotes anti-apoptotic gene expression in human pancreatic cancer cell lines. Tumour Biol. 2011;32:493-500 pubmed publisher
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| Hoang T, Bui T, Taguchi T, Watanabe T, Sato Y. All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein. J Exp Clin Cancer Res. 2010;29:165 pubmed publisher
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| Wang H, Gambosova K, Cooper Z, Holloway M, Kassai A, Izquierdo D, et al. EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic ?-cells. BMC Mol Biol. 2010;11:66 pubmed publisher
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| Zhou J, Gan N, Zhang W, Lu W, Xie X. Proliferation suppression and apoptosis of ovarian carcinoma cells induced by small interfering RNA against vascular endothelial growth factor. J Obstet Gynaecol Res. 2010;36:232-8 pubmed publisher
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| Zhou S, Qu X, Yu Z, Zhong L, Ruan M, Ma C, et al. Survivin as a potential early marker in the carcinogenesis of oral submucous fibrosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109:575-81 pubmed publisher
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| Wimmershoff J, Polkinghorne A, Grest P, Schade B, Marchal T, Keller S, et al. Immunohistochemical detection of survivin in canine lymphoma. J Comp Pathol. 2010;142:311-22 pubmed publisher
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| Kim Y, Lee E, Kim Y, Kim S, Park J, Myoung H, et al. Anti-cancer effects of celecoxib in head and neck carcinoma. Mol Cells. 2010;29:185-94 pubmed publisher
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| Kim Y, Kim S, Kim Y, Hong S, Kim M, Myoung H. Evaluation of survivin as a prognostic marker in oral squamous cell carcinoma. J Oral Pathol Med. 2010;39:368-75 pubmed publisher
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| Bennett K, Romigh T, Eng C. Disruption of transforming growth factor-beta signaling by five frequently methylated genes leads to head and neck squamous cell carcinoma pathogenesis. Cancer Res. 2009;69:9301-5 pubmed publisher
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| Yang L, Ma X, Xiao L, Tang M, Weng X, Sun L, et al. Uniquely modified RNA oligonucleotides targeting STAT3 suppress melanoma growth both in vitro and in vivo. Cancer Biol Ther. 2009;8:2065-72 pubmed
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| Koelink P, Mieremet Ooms M, Corver W, Wolanin K, Hommes D, Lamers C, et al. 5-aminosalicylic acid interferes in the cell cycle of colorectal cancer cells and induces cell death modes. Inflamm Bowel Dis. 2010;16:379-89 pubmed publisher
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| Chi H, Vu H, Iwasaki R, Thao L, Hara Y, Taguchi T, et al. Green tea (-)-epigalocatechin-3-gallate inhibits KIT activity and causes caspase-dependent cell death in gastrointestinal stromal tumor including imatinib-resistant cells. Cancer Biol Ther. 2009;8:1934-9 pubmed
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| Bourhis E, Lingel A, Phung Q, Fairbrother W, Cochran A. Phosphorylation of a borealin dimerization domain is required for proper chromosome segregation. Biochemistry. 2009;48:6783-93 pubmed publisher
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| Yang L, Xiao L, Ma X, Tang M, Weng X, Chen X, et al. Effect of DNAzymes targeting Akt1 on cell proliferation and apoptosis in nasopharyngeal carcinoma. Cancer Biol Ther. 2009;8:366-71 pubmed
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| Schünemann H, Castelli M, Muti P. Systematic reviews for the Journal of Experimental & Clinical Cancer Research: going where the science takes us. J Exp Clin Cancer Res. 2007;26:169-74 pubmed
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| Lukiw W, Cui J, Li Y, Culicchia F. Up-regulation of micro-RNA-221 (miRNA-221; chr Xp11.3) and caspase-3 accompanies down-regulation of the survivin-1 homolog BIRC1 (NAIP) in glioblastoma multiforme (GBM). J Neurooncol. 2009;91:27-32 pubmed publisher
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| Win H, Acevedo Duncan M. Atypical protein kinase C phosphorylates IKKalphabeta in transformed non-malignant and malignant prostate cell survival. Cancer Lett. 2008;270:302-11 pubmed publisher
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| Nakano J, Huang C, Liu D, Masuya D, Yokomise H, Ueno M, et al. The clinical significance of splice variants and subcellular localisation of survivin in non-small cell lung cancers. Br J Cancer. 2008;98:1109-17 pubmed publisher
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| Gonzalez S, Aubert S, Kerdraon O, Haddad O, Fantoni J, Biserte J, et al. Prognostic value of combined p53 and survivin in pT1G3 urothelial carcinoma of the bladder. Am J Clin Pathol. 2008;129:232-7 pubmed publisher
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| Holst C, Johansson V, Alm K, Oredsson S. Novel anti-apoptotic effect of Bcl-2: prevention of polyamine depletion-induced cell death. Cell Biol Int. 2008;32:66-74 pubmed
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| Bourhis E, Hymowitz S, Cochran A. The mitotic regulator Survivin binds as a monomer to its functional interactor Borealin. J Biol Chem. 2007;282:35018-23 pubmed
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| Braun F, Fecker L, Schwarz C, Walden P, Assaf C, Dürkop H, et al. Blockade of death receptor-mediated pathways early in the signaling cascade coincides with distinct apoptosis resistance in cutaneous T-cell lymphoma cells. J Invest Dermatol. 2007;127:2425-37 pubmed
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| Vischioni B, Oudejans J, Kruyt F, Giaccone G, Rodriguez J. Immunohistochemical detection of nuclear survivin in NSCLC: a comparison of commercial antibodies. Histopathology. 2007;50:671-5 pubmed
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| Calviello G, Resci F, Serini S, Piccioni E, Toesca A, Boninsegna A, et al. Docosahexaenoic acid induces proteasome-dependent degradation of beta-catenin, down-regulation of survivin and apoptosis in human colorectal cancer cells not expressing COX-2. Carcinogenesis. 2007;28:1202-9 pubmed
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| Kurbanov B, Fecker L, Geilen C, Sterry W, Eberle J. Resistance of melanoma cells to TRAIL does not result from upregulation of antiapoptotic proteins by NF-kappaB but is related to downregulation of initiator caspases and DR4. Oncogene. 2007;26:3364-77 pubmed
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| Shinohara E, Gonzalez A, Massion P, Chen H, Li M, Freyer A, et al. Nuclear survivin predicts recurrence and poor survival in patients with resected nonsmall cell lung carcinoma. Cancer. 2005;103:1685-92 pubmed
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| Lu B, Gonzalez A, Massion P, Shyr Y, Shaktour B, Carbone D, et al. Nuclear survivin as a biomarker for non-small-cell lung cancer. Br J Cancer. 2004;91:537-40 pubmed
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