| Published Application/Species/Sample/Dilution | Reference | 
|---|
| western blot; human; loading ...; fig 6d
 | Zhu H, Su Z, Ning J, Zhou L, Tan L, Sayed S, et al . Transmembrane protein 97 exhibits oncogenic properties via enhancing LRP6-mediated Wnt signaling in breast cancer. Cell Death Dis. 2021;12:912 pubmed  publisher | 
| western blot; human; 1:500; loading ...; fig 6f
 | Hsieh M, Weng C, Lin Y, Wu C, Chen L, Cheng K. Inhibition of β-Catenin Activity Abolishes LKB1 Loss-Driven Pancreatic Cystadenoma in Mice. Int J Mol Sci. 2021;22: pubmed  publisher | 
| western blot; human; loading ...; fig 10
 | Thangaraj K, Balasubramanian B, Park S, Natesan K, Liu W, Manju V. Orientin Induces G0/G1 Cell Cycle Arrest and Mitochondria Mediated Intrinsic Apoptosis in Human Colorectal Carcinoma HT29 Cells. Biomolecules. 2019;9: pubmed  publisher | 
| western blot; human; loading ...; fig 3d
 | Forte I, Indovina P, Iannuzzi C, Cirillo D, Di Marzo D, Barone D, et al . Targeted therapy based on p53 reactivation reduces both glioblastoma cell growth and resistance to temozolomide. Int J Oncol. 2019;54:2189-2199 pubmed  publisher | 
| western blot; human; loading ...; fig 5f
 | Urtishak K, Wang L, Culjkovic Kraljacic B, Davenport J, Porazzi P, Vincent T, et al . Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia. Oncogene. 2019;38:2241-2262 pubmed  publisher | 
| western blot; human; 1:200; loading ...; fig s3
 | Oldrini B, Hsieh W, Erdjument Bromage H, Codega P, Carro M, Curiel García A, et al . EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer. Nat Commun. 2017;8:2035 pubmed  publisher | 
| western blot; human; loading ...; fig 2b
 | Periyasamy M, Singh A, Gemma C, Kranjec C, Farzan R, Leach D, et al . p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells. Nucleic Acids Res. 2017;45:11056-11069 pubmed  publisher | 
| western blot; human; fig 2b
 | Liu Z, Li H, Liu J, Wu M, Chen X, Liu L, et al . Inactivated Wnt signaling in resveratrol-treated epidermal squamous cancer cells and its biological implication. Oncol Lett. 2017;14:2239-2243 pubmed  publisher | 
| immunohistochemistry; mouse; 1:100; loading ...; fig 6b
 | Sgourdou P, Mishra Gorur K, Saotome I, Henagariu O, Tuysuz B, Campos C, et al . Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly. Sci Rep. 2017;7:43708 pubmed  publisher | 
| immunohistochemistry; human; 1:100; loading ...; fig s3
 | Abadía Molina F, Morón Calvente V, Baird S, Shamim F, Martin F, MacKenzie A. Neuronal apoptosis inhibitory protein (NAIP) localizes to the cytokinetic machinery during cell division. Sci Rep. 2017;7:39981 pubmed  publisher | 
| western blot; human; loading ...; fig 2b
 | Park S, Jwa E, Shin S, Ju E, Park I, Pak J, et al . Ibulocydine sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis via calpain-mediated Bax cleavage. Int J Biochem Cell Biol. 2017;83:47-55 pubmed  publisher | 
| immunohistochemistry; human; 1:50; fig 4western blot; human; 1:200
 | Fotouhi O, Kjellin H, Larsson C, Hashemi J, Barriuso J, Juhlin C, et al . Proteomics Suggests a Role for APC-Survivin in Response to Somatostatin Analog Treatment of Neuroendocrine Tumors. J Clin Endocrinol Metab. 2016;101:3616-3627 pubmed | 
| immunohistochemistry - paraffin section; human; 1:50; fig 1
 | Takasaki C, Kobayashi M, Ishibashi H, Akashi T, Okubo K. Expression of hypoxia-inducible factor-1? affects tumor proliferation and antiapoptosis in surgically resected lung cancer. Mol Clin Oncol. 2016;5:295-300 pubmed | 
| immunocytochemistry; human; 1:300; fig 1western blot; human; fig 2
 | Sasai K, Katayama H, Hawke D, Sen S. Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex. PLoS ONE. 2016;11:e0157305 pubmed  publisher | 
| flow cytometry; human; 1:25; fig 1bimmunohistochemistry; human; loading ...; fig 1awestern blot; human; 1:50; fig 1d
 | Venkatesan N, Kanwar J, Deepa P, Navaneethakrishnan S, Joseph C, Krishnakumar S. Targeting HSP90/Survivin using a cell permeable structure based peptido-mimetic shepherdin in retinoblastoma. Chem Biol Interact. 2016;252:141-9 pubmed  publisher | 
| immunohistochemistry - paraffin section; human; fig 5
 | Andersson E, Arvidsson Y, Swärd C, Hofving T, Wängberg B, Kristiansson E, et al . Expression profiling of small intestinal neuroendocrine tumors identifies subgroups with clinical relevance, prognostic markers and therapeutic targets. Mod Pathol. 2016;29:616-29 pubmed  publisher | 
| western blot; human; fig 1
 | Li Y, Lu W, Saini S, Moukha Chafiq O, Pathak V, Ananthan S. Identification of quinazoline compounds as novel potent inhibitors of Wnt/?-catenin signaling in colorectal cancer cells. Oncotarget. 2016;7:11263-70 pubmed  publisher | 
| western blot; human; fig 5
 | Vartanian S, Ma T, Lee J, Haverty P, Kirkpatrick D, Yu K, et al . Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis. Mol Cell Proteomics. 2016;15:1220-31 pubmed  publisher | 
| western blot; human; fig 1
 | Ciamporcero E, Shen H, Ramakrishnan S, Yu Ku S, Chintala S, Shen L, et al . YAP activation protects urothelial cell carcinoma from treatment-induced DNA damage. Oncogene. 2016;35:1541-53 pubmed  publisher | 
| western blot; mouse; loading ...; fig 7d
 | Raimondi L, De Luca A, Amodio N, Manno M, Raccosta S, Taverna S, et al . Involvement of multiple myeloma cell-derived exosomes in osteoclast differentiation. Oncotarget. 2015;6:13772-89 pubmed | 
| western blot; human; 1:75
 | Rogler A, Kendziorra E, Giedl J, Stoehr C, Taubert H, Goebell P, et al . Functional analyses and prognostic significance of SFRP1 expression in bladder cancer. J Cancer Res Clin Oncol. 2015;141:1779-90 pubmed  publisher | 
|  | Papanikolaou V, Stefanou N, Dubos S, Papathanasiou I, Palianopoulou M, Valiakou V, et al . Synergy of leptin/STAT3 with HER2 receptor induces tamoxifen resistance in breast cancer cells through regulation of apoptosis-related genes. Cell Oncol (Dordr). 2015;38:155-64 pubmed  publisher | 
| western blot; mouse; fig 6
 | Olayanju A, Copple I, Bryan H, Edge G, Sison R, Wong M, et al . Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2. Free Radic Biol Med. 2015;78:202-12 pubmed  publisher | 
|  | Leiphrakpam P, Rajput A, Mathiesen M, Agarwal E, Lazenby A, Are C, et al . Ezrin expression and cell survival regulation in colorectal cancer. Cell Signal. 2014;26:868-79 pubmed  publisher | 
|  | Cheng Y, Holloway M, Nguyen K, McCauley D, Landesman Y, Kauffman M, et al . XPO1 (CRM1) inhibition represses STAT3 activation to drive a survivin-dependent oncogenic switch in triple-negative breast cancer. Mol Cancer Ther. 2014;13:675-86 pubmed  publisher | 
| immunohistochemistry - paraffin section; human; 1:50
 | Lauxen I, Oliveira M, Rados P, Lingen M, Nor J, Sant Ana Filho M. Immunoprofiling of oral squamous cell carcinomas reveals high p63 and survivin expression. Oral Dis. 2014;20:e76-80 pubmed  publisher | 
| immunohistochemistry - paraffin section; human; 1:50
 | Kobayashi M, Huang C, Sonobe M, Kikuchi R, Ishikawa M, Kitamura J, et al . Intratumoral Wnt2B expression affects tumor proliferation and survival in malignant pleural mesothelioma patients. Exp Ther Med. 2012;3:952-958 pubmed | 
| western blot; human; 1:100
 | Liu D, Kadota K, Ueno M, Nakashima N, Yokomise H, Huang C. Adenoviral vector expressing short hairpin RNA targeting Wnt2B has an effective antitumour activity against Wnt2B2-overexpressing tumours. Eur J Cancer. 2012;48:1208-18 pubmed  publisher | 
|  | Zhao B, Song A, Haque R, Lei F, Weiler L, Xiong X, et al . Cooperation between molecular targets of costimulation in promoting T cell persistence and tumor regression. J Immunol. 2009;182:6744-52 pubmed  publisher | 
|  | Mohammed Salama M. Role of Napsin A and Survivin Immunohistochemical Expression in Bronchogenic Adenocarcinoma. Asian Pac J Cancer Prev. 2020;21:3345-3348 pubmed  publisher | 
|  | Jin L, Zhao K, Xu L, Zhao R, Werle K, Wang Y, et al . LKB1 inactivation leads to centromere defects and genome instability via p53-dependent upregulation of survivin. Aging (Albany NY). 2020;12:14341-14354 pubmed  publisher | 
|  | Lee J, Lee H, Ryu K, Kim M, Ko D, Chung K, et al . KCP10043F Represses the Proliferation of Human Non-Small Cell Lung Cancer Cells by Caspase-Mediated Apoptosis via STAT3 Inactivation. J Clin Med. 2020;9: pubmed  publisher | 
|  | Carpi S, Fogli S, Giannetti A, Adinolfi B, Tombelli S, Da Pozzo E, et al . Theranostic properties of a survivin-directed molecular beacon in human melanoma cells. PLoS ONE. 2014;9:e114588 pubmed  publisher | 
|  | Macha M, Rachagani S, Gupta S, Pai P, Ponnusamy M, Batra S, et al . Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling. Cancer Lett. 2013;341:166-77 pubmed  publisher | 
|  | Lazarova D, Chiaro C, Wong T, Drago E, Rainey A, O Malley S, et al . CBP Activity Mediates Effects of the Histone Deacetylase Inhibitor Butyrate on WNT Activity and Apoptosis in Colon Cancer Cells. J Cancer. 2013;4:481-90 pubmed  publisher | 
|  | Ly B, Chi H, Yamagishi M, Kano Y, Hara Y, Nakano K, et al . Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells. PLoS ONE. 2013;8:e66378 pubmed  publisher | 
|  | Nair S, Marlow F, ABRAMS E, KAPP L, Mullins M, Pelegri F. The chromosomal passenger protein birc5b organizes microfilaments and germ plasm in the zebrafish embryo. PLoS Genet. 2013;9:e1003448 pubmed  publisher | 
|  | Cui C, Wang Y, Wang Y, Zhao M, Peng S. Alsterpaullone, a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells through Apoptosis-Inducing Effect. J Anal Methods Chem. 2013;2013:602091 pubmed  publisher | 
|  | Al Dhaheri Y, Eid A, Abuqamar S, Attoub S, Khasawneh M, Aiche G, et al . Mitotic arrest and apoptosis in breast cancer cells induced by Origanum majorana extract: upregulation of TNF-? and downregulation of survivin and mutant p53. PLoS ONE. 2013;8:e56649 pubmed  publisher | 
|  | Chi H, Ly B, Kano Y, Tojo A, Watanabe T, Sato Y. ETV6-NTRK3 as a therapeutic target of small molecule inhibitor PKC412. Biochem Biophys Res Commun. 2012;429:87-92 pubmed  publisher | 
|  | Li J, Wang H, Ma Z, Fan W, Li Y, Han B, et al . TAT-Apoptin induces apoptosis in the human bladder cancer EJ cell line and regulates Bax, Bcl-2, caspase-3 and survivin expression. Exp Ther Med. 2012;3:1033-1038 pubmed | 
|  | Freiburghaus C, Lindmark Månsson H, Paulsson M, Oredsson S. Reduction of ultraviolet light-induced DNA damage in human colon cancer cells treated with a lactoferrin-derived peptide. J Dairy Sci. 2012;95:5552-60 pubmed  publisher | 
|  | McCarthy B, Yang L, Ding J, Ren M, King W, Elsalanty M, et al . NF-?B2 mutation targets survival, proliferation and differentiation pathways in the pathogenesis of plasma cell tumors. BMC Cancer. 2012;12:203 pubmed  publisher | 
|  | al Yacoub N, Fecker L, Möbs M, Plötz M, Braun F, Sterry W, et al . Apoptosis induction by SAHA in cutaneous T-cell lymphoma cells is related to downregulation of c-FLIP and enhanced TRAIL signaling. J Invest Dermatol. 2012;132:2263-74 pubmed  publisher | 
|  | Yuan B, Xian R, Wu X, Jing J, Chen K, Liu G, et al . Endoplasmic reticulum chaperone glucose regulated protein 170-Pokemon complexes elicit a robust antitumor immune response in vivo. Immunobiology. 2012;217:738-42 pubmed  publisher | 
|  | Glienke W, Maute L, Wicht J, Bergmann L. The dual PI3K/mTOR inhibitor NVP-BGT226 induces cell cycle arrest and regulates Survivin gene expression in human pancreatic cancer cell lines. Tumour Biol. 2012;33:757-65 pubmed  publisher | 
|  | Ekeblad S, Lejonklou M, Stalberg P, Skogseid B. Prognostic relevance of survivin in pancreatic endocrine tumors. World J Surg. 2012;36:1411-8 pubmed  publisher | 
|  | Wang Z, Zhao J, Zeng J, Wu K, Chen Y, Wang X, et al . Specific survivin dual fluorescence resonance energy transfer molecular beacons for detection of human bladder cancer cells. Acta Pharmacol Sin. 2011;32:1522-8 pubmed  publisher | 
|  | Zhang C, Elkahloun A, Robertson M, Gills J, Tsurutani J, Shih J, et al . Loss of cytoplasmic CDK1 predicts poor survival in human lung cancer and confers chemotherapeutic resistance. PLoS ONE. 2011;6:e23849 pubmed  publisher | 
|  | Morrison D, Hogan L, Condos G, Bhatla T, Germino N, Moskowitz N, et al . Endogenous knockdown of survivin improves chemotherapeutic response in ALL models. Leukemia. 2012;26:271-9 pubmed  publisher | 
|  | Zhou F, Zhang L, van Laar T, van Dam H, Ten Dijke P. GSK3? inactivation induces apoptosis of leukemia cells by repressing the function of c-Myb. Mol Biol Cell. 2011;22:3533-40 pubmed  publisher | 
|  | Nardiello T, Jungbluth A, Mei A, DiLiberto M, Huang X, Dabrowski A, et al . MAGE-A inhibits apoptosis in proliferating myeloma cells through repression of Bax and maintenance of survivin. Clin Cancer Res. 2011;17:4309-19 pubmed  publisher | 
|  | Jeong J, Jin C, Park C, Hong S, Kim G, Jeong Y, et al . Induction of apoptosis by cordycepin via reactive oxygen species generation in human leukemia cells. Toxicol In Vitro. 2011;25:817-24 pubmed  publisher | 
|  | Huang J, Wang F, Okuka M, Liu N, Ji G, Ye X, et al . Association of telomere length with authentic pluripotency of ES/iPS cells. Cell Res. 2011;21:779-92 pubmed  publisher | 
|  | Liu F, Hu X, Zimmerman M, Waller J, Wu P, Hayes Jordan A, et al . TNF? cooperates with IFN-? to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis. PLoS ONE. 2011;6:e16241 pubmed  publisher | 
|  | Glienke W, Hausmann E, Bergmann L. Downregulation of STAT3 signaling induces apoptosis but also promotes anti-apoptotic gene expression in human pancreatic cancer cell lines. Tumour Biol. 2011;32:493-500 pubmed  publisher | 
|  | Hoang T, Bui T, Taguchi T, Watanabe T, Sato Y. All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein. J Exp Clin Cancer Res. 2010;29:165 pubmed  publisher | 
|  | Wang H, Gambosova K, Cooper Z, Holloway M, Kassai A, Izquierdo D, et al . EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic ?-cells. BMC Mol Biol. 2010;11:66 pubmed  publisher | 
|  | Zhou J, Gan N, Zhang W, Lu W, Xie X. Proliferation suppression and apoptosis of ovarian carcinoma cells induced by small interfering RNA against vascular endothelial growth factor. J Obstet Gynaecol Res. 2010;36:232-8 pubmed  publisher | 
|  | Zhou S, Qu X, Yu Z, Zhong L, Ruan M, Ma C, et al . Survivin as a potential early marker in the carcinogenesis of oral submucous fibrosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109:575-81 pubmed  publisher | 
|  | Wimmershoff J, Polkinghorne A, Grest P, Schade B, Marchal T, Keller S, et al . Immunohistochemical detection of survivin in canine lymphoma. J Comp Pathol. 2010;142:311-22 pubmed  publisher | 
|  | Kim Y, Lee E, Kim Y, Kim S, Park J, Myoung H, et al . Anti-cancer effects of celecoxib in head and neck carcinoma. Mol Cells. 2010;29:185-94 pubmed  publisher | 
|  | Kim Y, Kim S, Kim Y, Hong S, Kim M, Myoung H. Evaluation of survivin as a prognostic marker in oral squamous cell carcinoma. J Oral Pathol Med. 2010;39:368-75 pubmed  publisher | 
|  | Bennett K, Romigh T, Eng C. Disruption of transforming growth factor-beta signaling by five frequently methylated genes leads to head and neck squamous cell carcinoma pathogenesis. Cancer Res. 2009;69:9301-5 pubmed  publisher | 
|  | Yang L, Ma X, Xiao L, Tang M, Weng X, Sun L, et al . Uniquely modified RNA oligonucleotides targeting STAT3 suppress melanoma growth both in vitro and in vivo. Cancer Biol Ther. 2009;8:2065-72 pubmed | 
|  | Koelink P, Mieremet Ooms M, Corver W, Wolanin K, Hommes D, Lamers C, et al . 5-aminosalicylic acid interferes in the cell cycle of colorectal cancer cells and induces cell death modes. Inflamm Bowel Dis. 2010;16:379-89 pubmed  publisher | 
|  | Chi H, Vu H, Iwasaki R, Thao L, Hara Y, Taguchi T, et al . Green tea (-)-epigalocatechin-3-gallate inhibits KIT activity and causes caspase-dependent cell death in gastrointestinal stromal tumor including imatinib-resistant cells. Cancer Biol Ther. 2009;8:1934-9 pubmed | 
|  | Bourhis E, Lingel A, Phung Q, Fairbrother W, Cochran A. Phosphorylation of a borealin dimerization domain is required for proper chromosome segregation. Biochemistry. 2009;48:6783-93 pubmed  publisher | 
|  | Yang L, Xiao L, Ma X, Tang M, Weng X, Chen X, et al . Effect of DNAzymes targeting Akt1 on cell proliferation and apoptosis in nasopharyngeal carcinoma. Cancer Biol Ther. 2009;8:366-71 pubmed | 
|  | Schünemann H, Castelli M, Muti P. Systematic reviews for the Journal of Experimental & Clinical Cancer Research: going where the science takes us. J Exp Clin Cancer Res. 2007;26:169-74 pubmed | 
|  | Lukiw W, Cui J, Li Y, Culicchia F. Up-regulation of micro-RNA-221 (miRNA-221; chr Xp11.3) and caspase-3 accompanies down-regulation of the survivin-1 homolog BIRC1 (NAIP) in glioblastoma multiforme (GBM). J Neurooncol. 2009;91:27-32 pubmed  publisher | 
|  | Win H, Acevedo Duncan M. Atypical protein kinase C phosphorylates IKKalphabeta in transformed non-malignant and malignant prostate cell survival. Cancer Lett. 2008;270:302-11 pubmed  publisher | 
|  | Nakano J, Huang C, Liu D, Masuya D, Yokomise H, Ueno M, et al . The clinical significance of splice variants and subcellular localisation of survivin in non-small cell lung cancers. Br J Cancer. 2008;98:1109-17 pubmed  publisher | 
|  | Gonzalez S, Aubert S, Kerdraon O, Haddad O, Fantoni J, Biserte J, et al . Prognostic value of combined p53 and survivin in pT1G3 urothelial carcinoma of the bladder. Am J Clin Pathol. 2008;129:232-7 pubmed  publisher | 
|  | Holst C, Johansson V, Alm K, Oredsson S. Novel anti-apoptotic effect of Bcl-2: prevention of polyamine depletion-induced cell death. Cell Biol Int. 2008;32:66-74 pubmed | 
|  | Bourhis E, Hymowitz S, Cochran A. The mitotic regulator Survivin binds as a monomer to its functional interactor Borealin. J Biol Chem. 2007;282:35018-23 pubmed | 
|  | Braun F, Fecker L, Schwarz C, Walden P, Assaf C, Dürkop H, et al . Blockade of death receptor-mediated pathways early in the signaling cascade coincides with distinct apoptosis resistance in cutaneous T-cell lymphoma cells. J Invest Dermatol. 2007;127:2425-37 pubmed | 
|  | Vischioni B, Oudejans J, Kruyt F, Giaccone G, Rodriguez J. Immunohistochemical detection of nuclear survivin in NSCLC: a comparison of commercial antibodies. Histopathology. 2007;50:671-5 pubmed | 
|  | Calviello G, Resci F, Serini S, Piccioni E, Toesca A, Boninsegna A, et al . Docosahexaenoic acid induces proteasome-dependent degradation of beta-catenin, down-regulation of survivin and apoptosis in human colorectal cancer cells not expressing COX-2. Carcinogenesis. 2007;28:1202-9 pubmed | 
|  | Kurbanov B, Fecker L, Geilen C, Sterry W, Eberle J. Resistance of melanoma cells to TRAIL does not result from upregulation of antiapoptotic proteins by NF-kappaB but is related to downregulation of initiator caspases and DR4. Oncogene. 2007;26:3364-77 pubmed | 
|  | Shinohara E, Gonzalez A, Massion P, Chen H, Li M, Freyer A, et al . Nuclear survivin predicts recurrence and poor survival in patients with resected nonsmall cell lung carcinoma. Cancer. 2005;103:1685-92 pubmed | 
|  | Lu B, Gonzalez A, Massion P, Shyr Y, Shaktour B, Carbone D, et al . Nuclear survivin as a biomarker for non-small-cell lung cancer. Br J Cancer. 2004;91:537-40 pubmed |