product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
CUL-1 (D-5) Antibody
catalog :
sc-17775
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D-5
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1b
Paul D, Islam S, Manne R, Dinesh U, Malonia S, Maity B, et al. F-box protein FBXO16 functions as a tumor suppressor by attenuating nuclear β-catenin function. J Pathol. 2019;248:266-279 pubmed publisher
  • western blot; human; loading ...; fig 8c
Liu R, Moss B. Vaccinia Virus C9 Ankyrin Repeat/F-Box Protein Is a Newly Identified Antagonist of the Type I Interferon-Induced Antiviral State. J Virol. 2018;92: pubmed publisher
  • western blot; human; loading ...; fig 5b
Scott D, Hammill J, Min J, Rhee D, Connelly M, Sviderskiy V, et al. Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase. Nat Chem Biol. 2017;13:850-857 pubmed publisher
  • western blot; human; 1:500; fig s2
Vingill S, Brockelt D, Lancelin C, Tatenhorst L, Dontcheva G, Preisinger C, et al. Loss of FBXO7 (PARK15) results in reduced proteasome activity and models a parkinsonism-like phenotype in mice. EMBO J. 2016;35:2008-25 pubmed publisher
  • western blot; human; loading ...; fig 1a
Shao W, Zumer K, Fujinaga K, Peterlin B. FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator). J Biol Chem. 2016;291:17953-63 pubmed publisher
  • western blot; mouse; loading ...; fig s4d
Shin H, Kim H, Oh S, Lee J, Kee M, Ko H, et al. AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy. Nature. 2016;534:553-7 pubmed publisher
  • western blot; human; fig 6
Mosadeghi R, Reichermeier K, Winkler M, Schreiber A, Reitsma J, Zhang Y, et al. Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle. elife. 2016;5: pubmed publisher
  • western blot; human; fig 4a
Matsunuma R, Niida H, Ohhata T, Kitagawa K, Sakai S, Uchida C, et al. UV Damage-Induced Phosphorylation of HBO1 Triggers CRL4DDB2-Mediated Degradation To Regulate Cell Proliferation. Mol Cell Biol. 2016;36:394-406 pubmed publisher
  • western blot; human; loading ...; fig 2b
Chen Z, Liu B, Tang N, Xu Y, Ye X, Li Z, et al. FBXL5-mediated degradation of single-stranded DNA-binding protein hSSB1 controls DNA damage response. Nucleic Acids Res. 2014;42:11560-9 pubmed publisher
  • western blot; human
Li S, Song W, Jiang M, Zeng L, Zhu X, Chen J. Phosphorylation of cyclin Y by CDK14 induces its ubiquitination and degradation. FEBS Lett. 2014;588:1989-96 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 4b
  • western blot; human; loading ...; fig 4b
Levay K, Slepak V. Regulation of Cop9 signalosome activity by the EF-hand Ca2+-binding protein tescalcin. J Cell Sci. 2014;127:2448-59 pubmed publisher
Liu R, Olano L, Mirzakhanyan Y, Gershon P, Moss B. Vaccinia Virus Ankyrin-Repeat/F-Box Protein Targets Interferon-Induced IFITs for Proteasomal Degradation. Cell Rep. 2019;29:816-828.e6 pubmed publisher
Li Y, Liu Y, Xu H, Jiang G, Van der Jeught K, Fang Y, et al. Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II. Nat Commun. 2018;9:4394 pubmed publisher
Raghavan S, Singh N, Mani A, Rao G. Protease-activated receptor 1 inhibits cholesterol efflux and promotes atherogenesis via cullin 3-mediated degradation of the ABCA1 transporter. J Biol Chem. 2018;293:10574-10589 pubmed publisher
Hu Y, O Boyle K, Auer J, Raju S, You F, Wang P, et al. Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα. PLoS Pathog. 2017;13:e1006187 pubmed publisher
Wrzosek L, Miquel S, Noordine M, Bouet S, Joncquel Chevalier Curt M, Robert V, et al. Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent. BMC Biol. 2013;11:61 pubmed publisher
Turpin W, Humblot C, Noordine M, Wrzosek L, Tomas J, Mayeur C, et al. Behavior of lactobacilli isolated from fermented slurry (ben-saalga) in gnotobiotic rats. PLoS ONE. 2013;8:e57711 pubmed publisher
Liu B, Zheng Y, Wang T, Xu H, Xia L, Zhang J, et al. Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. J Proteome Res. 2012;11:1773-81 pubmed publisher
Van Rechem C, Black J, Abbas T, Allen A, Rinehart C, Yuan G, et al. The SKP1-Cul1-F-box and leucine-rich repeat protein 4 (SCF-FbxL4) ubiquitin ligase regulates lysine demethylase 4A (KDM4A)/Jumonji domain-containing 2A (JMJD2A) protein. J Biol Chem. 2011;286:30462-70 pubmed publisher
product information
Product Name :
CUL-1 (D-5) Antibody
Gene Name :
CUL1
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-17775
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
CUL-1
reactive species  :
m, r, h
Application :
WB, IP, IF, ELISA
Epitope :
57-269 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA