product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Ref-1 (C-4) Antibody
catalog :
sc-17774
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-4
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 13
Reference
Wang R, Li C, Qiao P, Xue Y, Zheng X, Chen H, et al. OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos. Cell Death Dis. 2018;9:628 pubmed publisher
Kim M, Kim H, Yoon S, Lim S, Cha M, Jeon Y, et al. Colon cancer progression is driven by APEX1-mediated upregulation of Jagged. J Clin Invest. 2013;: pubmed publisher
Singh B, Bhat N, Bhat H. Partial inhibition of estrogen-induced mammary carcinogenesis in rats by tamoxifen: balance between oxidant stress and estrogen responsiveness. PLoS ONE. 2011;6:e25125 pubmed publisher
Lee S, Chung J, Park M, Joo H, Lee E, Cho E, et al. Apurinic/apyrimidinic endonuclease 1 inhibits protein kinase C-mediated p66shc phosphorylation and vasoconstriction. Cardiovasc Res. 2011;91:502-9 pubmed publisher
Fung H, Demple B. Distinct roles of Ape1 protein in the repair of DNA damage induced by ionizing radiation or bleomycin. J Biol Chem. 2011;286:4968-77 pubmed publisher
Son Y, Heo J, Kim T, Jeon Y, Kim J, Lee J. Over-expression of JunB inhibits mitochondrial stress and cytotoxicity in human lymphoma cells exposed to chronic oxidative stress. BMB Rep. 2010;43:57-61 pubmed
Curtis C, Thorngren D, Nardulli A. Immunohistochemical analysis of oxidative stress and DNA repair proteins in normal mammary and breast cancer tissues. BMC Cancer. 2010;10:9 pubmed publisher
Ku W, Chiu S, Chen Y, Huang H, Wu W, Chen Y. Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2. Mol Cell Proteomics. 2009;8:2034-50 pubmed publisher
Ouellet V, Ling T, Normandin K, Madore J, Lussier C, Barrès V, et al. Immunohistochemical profiling of benign, low malignant potential and low grade serous epithelial ovarian tumors. BMC Cancer. 2008;8:346 pubmed publisher
Bennett P, Ishchenko A, Laval J, Paap B, Sutherland B. Endogenous DNA damage clusters in human hematopoietic stem and progenitor cells. Free Radic Biol Med. 2008;45:1352-9 pubmed publisher
Fung H, Liu P, Demple B. ATF4-dependent oxidative induction of the DNA repair enzyme Ape1 counteracts arsenite cytotoxicity and suppresses arsenite-mediated mutagenesis. Mol Cell Biol. 2007;27:8834-47 pubmed
Godschalk R, Albrecht C, Curfs D, Schins R, Bartsch H, van Schooten F, et al. Decreased levels of lipid peroxidation-induced DNA damage in the onset of atherogenesis in apolipoprotein E deficient mice. Mutat Res. 2007;621:87-94 pubmed
Ouellet V, Le Page C, Guyot M, Lussier C, Tonin P, Provencher D, et al. SET complex in serous epithelial ovarian cancer. Int J Cancer. 2006;119:2119-26 pubmed
product information
Product Name :
Ref-1 (C-4) Antibody
Gene Name :
APEX1
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-17774
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Ref-1
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P)
Epitope :
1-300 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA