product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Chk2 (A-11) Antibody
catalog :
sc-17747
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A-11
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig s4c
Sonego M, Pellarin I, Costa A, Vinciguerra G, Coan M, Kraut A, et al. USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability. Sci Adv. 2019;5:eaav3235 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s4c
Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O Neil N, et al. CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours. Nat Commun. 2017;8:14432 pubmed publisher
  • immunoprecipitation; human; 1:500; loading ...; fig 1b
  • western blot; human; 1:500; loading ...; fig 2a,2b
  • western blot; mouse; 1:500; loading ...; fig 6e
Xu X, Fan Z, Liang C, Li L, Wang L, Liang Y, et al. A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity. Nat Commun. 2017;8:14059 pubmed publisher
  • western blot; human; loading ...; fig 1a
Preet R, Siddharth S, Satapathy S, Das S, Nayak A, Das D, et al. Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade. Biochem Pharmacol. 2016;105:23-33 pubmed publisher
  • western blot; human; fig 2d
Baude A, Aaes T, Zhai B, Al Nakouzi N, Oo H, Daugaard M, et al. Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination. Nucleic Acids Res. 2016;44:2214-26 pubmed publisher
  • western blot; human
Solier S, Sordet O, Kohn K, Pommier Y. Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways. Mol Cell Biol. 2009;29:68-82 pubmed publisher
Wu Z, Qiu M, Guo Y, Zhao J, Liu Z, Wang H, et al. OTU deubiquitinase 4 is silenced and radiosensitizes non-small cell lung cancer cells via inhibiting DNA repair. Cancer Cell Int. 2019;19:99 pubmed publisher
Werner C, Gensch C, Pöss J, Haendeler J, Bohm M, Laufs U. Pioglitazone activates aortic telomerase and prevents stress-induced endothelial apoptosis. Atherosclerosis. 2011;216:23-34 pubmed publisher
Makino N, Maeda T, Oyama J, Sasaki M, Higuchi Y, Mimori K, et al. Antioxidant therapy attenuates myocardial telomerase activity reduction in superoxide dismutase-deficient mice. J Mol Cell Cardiol. 2011;50:670-7 pubmed publisher
Vempati R, Jayani R, Notani D, Sengupta A, Galande S, Haldar D. p300-mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammals. J Biol Chem. 2010;285:28553-64 pubmed publisher
Tomko R, Azang Njaah N, Lazo J. Nitrosative stress suppresses checkpoint activation after DNA synthesis inhibition. Cell Cycle. 2009;8:299-305 pubmed
Lu L, Wang Y. Immunoprecipitation alert: DNA binding proteins directly bind to protein A/G without any antibody as the bridge. Cell Cycle. 2008;7:417-8 pubmed
Berkovich E, Monnat R, Kastan M. Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair. Nat Cell Biol. 2007;9:683-90 pubmed
product information
Product Name :
Chk2 (A-11) Antibody
Gene Name :
CHEK2
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-17747
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Chk2
reactive species  :
m, r, h
Application :
WB, IP, IF, ELISA
Epitope :
1-300 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA