product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
FAK (H-1) Antibody
catalog :
sc-1688
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H-1
reactivity :
Domestic guinea pig, human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 23
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 6A
Chung C, Chang C, Hsu C, Lin K, Peng H, Huang T. Aggretin Venom Polypeptide as a Novel Anti-angiogenesis Agent by Targeting Integrin alpha2beta1. Sci Rep. 2017;7:43612 pubmed publisher
  • immunocytochemistry; Domestic guinea pig; 1:100; fig 1
  • western blot; Domestic guinea pig; 1:100; fig 1
Roa-Espitia A, Hernández-Rendón E, Baltiérrez-Hoyos R, Muñoz-Gotera R, Cote-Vélez A, Jiménez I, et al. Focal adhesion kinase is required for actin polymerization and remodeling of the cytoskeleton during sperm capacitation. Biol Open. 2016;5:1189-99 pubmed publisher
  • western blot; human; loading ...; fig 5d
Niu G, Ye T, Qin L, Bourbon P, Chang C, Zhao S, et al. Orphan nuclear receptor TR3/Nur77 improves wound healing by upregulating the expression of integrin β4. FASEB J. 2015;29:131-40 pubmed publisher
  • western blot; human; fig 6
Menhofer M, Bartel D, Liebl J, Kubisch R, Busse J, Wagner E, et al. In vitro and in vivo characterization of the actin polymerizing compound chondramide as an angiogenic inhibitor. Cardiovasc Res. 2014;104:303-14 pubmed publisher
Son S, Kim S, Moon E, Kim D, Pyo S, Um S. Prognostic significance and function of the vacuolar H+-ATPase subunit V1E1 in esophageal squamous cell carcinoma. Oncotarget. 2016;7:49334-49348 pubmed publisher
Cheng T, Tu S, Chen L, Chen M, Chen W, Lin Y, et al. Down-regulation of α-L-fucosidase 1 expression confers inferior survival for triple-negative breast cancer patients by modulating the glycosylation status of the tumor cell surface. Oncotarget. 2015;6:21283-300 pubmed
Bernard-Trifilo J, Lim S, Hou S, Schlaepfer D, Ilic D. Analyzing FAK and Pyk2 in early integrin signaling events. Curr Protoc Cell Biol. 2006;0:Unit 14.7 pubmed publisher
Fan D, Shi H. Pilot study: alteration of deleted in liver cancer1 and phosphorylated focal adhesion kinase Y397 cytoplasmic expression and the prognostic value in advanced epithelial ovarian carcinoma. Int J Mol Sci. 2011;12:8489-501 pubmed publisher
Theocharis S, Klijanienko J, Giaginis C, Alexandrou P, Patsouris E, Sastre-Garau X. FAK and Src expression in mobile tongue squamous cell carcinoma: associations with clinicopathological parameters and patients survival. J Cancer Res Clin Oncol. 2012;138:1369-77 pubmed publisher
Goutzanis L, Vairaktaris E, Yapijakis C, Kavantzas N, Nkenke E, Derka S, et al. Diabetes may increase risk for oral cancer through the insulin receptor substrate-1 and focal adhesion kinase pathway. Oral Oncol. 2007;43:165-73 pubmed
Chatzizacharias N, Giaginis C, Gatzidou E, Tsourouflis G, Sfiniadakis I, Alexandrou P, et al. Expression and clinical significance of FAK and Src proteins in human endometrial adenocarcinoma. Pathol Oncol Res. 2011;17:277-85 pubmed publisher
Carr H, Zuo Y, Oh W, Frost J. Regulation of focal adhesion kinase activation, breast cancer cell motility, and amoeboid invasion by the RhoA guanine nucleotide exchange factor Net1. Mol Cell Biol. 2013;33:2773-86 pubmed publisher
Orazizadeh M, Rashidi I, Saremi J, Latifi M. Focal adhesion kinase (FAK) involvement in human endometrial remodeling during the menstrual cycle. Iran Biomed J. 2009;13:95-101 pubmed
Giaginis C, Vgenopoulou S, Tsourouflis G, Politi E, Kouraklis G, Theocharis S. Expression and clinical significance of focal adhesion kinase in the two distinct histological types, intestinal and diffuse, of human gastric adenocarcinoma. Pathol Oncol Res. 2009;15:173-81 pubmed publisher
Bock O, Muth M, Theophile K, Winter M, Hussein K, Büsche G, et al. Identification of new target molecules PTK2, TGFBR2 and CD9 overexpressed during advanced bone marrow remodelling in primary myelofibrosis. Br J Haematol. 2009;146:510-20 pubmed publisher
Michailidi C, Giaginis C, Stolakis V, Alexandrou P, Klijanienko J, Delladetsima I, et al. Evaluation of FAK and Src expression in human benign and malignant thyroid lesions. Pathol Oncol Res. 2010;16:497-507 pubmed publisher
Sheng B, Song B, Zheng Z, Zhou F, Lu G, Zhao N, et al. Abnormal cleavage of APP impairs its functions in cell adhesion and migration. Neurosci Lett. 2009;450:327-31 pubmed publisher
Dufour C, Holy X, Marie P. Transforming growth factor-beta prevents osteoblast apoptosis induced by skeletal unloading via PI3K/Akt, Bcl-2, and phospho-Bad signaling. Am J Physiol Endocrinol Metab. 2008;294:E794-801 pubmed publisher
Riemenschneider M, Mueller W, Betensky R, Mohapatra G, Louis D. In situ analysis of integrin and growth factor receptor signaling pathways in human glioblastomas suggests overlapping relationships with focal adhesion kinase activation. Am J Pathol. 2005;167:1379-87 pubmed
Dufour C, Holy X, Marie P. Skeletal unloading induces osteoblast apoptosis and targets alpha5beta1-PI3K-Bcl-2 signaling in rat bone. Exp Cell Res. 2007;313:394-403 pubmed
Jiang W, Ye L, Ji K, Frewer N, Ji J, Mason M. Inhibitory effects of Yangzheng Xiaoji on angiogenesis and the role of the focal adhesion kinase pathway. Int J Oncol. 2012;41:1635-42 pubmed publisher
Jiang W, Ye L, Ji K, Ruge F, Wu Y, Gao Y, et al. Antitumour effects of Yangzheng Xiaoji in human osteosarcoma: the pivotal role of focal adhesion kinase signalling. Oncol Rep. 2013;30:1405-13 pubmed publisher
Wang C, Yang R, Yue D, Zhang Z. Expression of FAK and PTEN in bronchioloalveolar carcinoma and lung adenocarcinoma. Lung. 2009;187:104-9 pubmed publisher
product information
Product Name :
FAK (H-1) Antibody
Gene Name :
PTK2
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-1688
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
FAK
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), FCM
Epitope :
903-1052 (m)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
www.scbt.com
1.800.457.3801
headquarters: USA