Published Application/Species/Sample/Dilution | Reference |
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- western blot knockout validation; mouse; loading ...; fig 8d, s8
| Wang W, Bale S, Wei J, Yalavarthi B, Bhattacharyya D, Yan J, et al. Fibroblast A20 governs fibrosis susceptibility and its repression by DREAM promotes fibrosis in multiple organs. Nat Commun. 2022;13:6358 pubmed publisher
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- western blot knockout validation; mouse; loading ...; fig s6a
| Son M, Wang A, Tu H, Metzig M, Patel P, Husain K, et al. NF-κB responds to absolute differences in cytokine concentrations. Sci Signal. 2021;14: pubmed
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- flow cytometry; human; loading ...; fig 6b
| Sun R, Hedl M, Abraham C. TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants. Cell Mol Gastroenterol Hepatol. 2021;11:249-272 pubmed publisher
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- western blot; human; loading ...; fig 2a
| Lafont E, Kantari Mimoun C, Dráber P, De Miguel D, Hartwig T, Reichert M, et al. The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death. EMBO J. 2017;36:1147-1166 pubmed publisher
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- western blot; human; loading ...; fig 4a
| Afonina I, Van Nuffel E, Baudelet G, Driege Y, Kreike M, Staal J, et al. The paracaspase MALT1 mediates CARD14-induced signaling in keratinocytes. EMBO Rep. 2016;17:914-27 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:200; fig 2
- western blot; human; 1:1000; fig 1
| Wang Y, Wan M, Zhou Q, Wang H, Wang Z, Zhong X, et al. The Prognostic Role of SOCS3 and A20 in Human Cholangiocarcinoma. PLoS ONE. 2015;10:e0141165 pubmed publisher
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- immunoprecipitation; mouse; 1:50
- western blot; mouse; 1:50
| Kanayama M, Inoue M, Danzaki K, Hammer G, He Y, Shinohara M. Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity. Nat Commun. 2015;6:5779 pubmed publisher
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| Kasama Y, Mizukami T, Kusunoki H, Peveling Oberhag J, Nishito Y, Ozawa M, et al. B-cell-intrinsic hepatitis C virus expression leads to B-cell-lymphomagenesis and induction of NF-?B signalling. PLoS ONE. 2014;9:e91373 pubmed publisher
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| Yang M, Yu X, Li X, Luo B, Yang W, Lin Y, et al. TNFAIP3 is required for FGFR1 activation-promoted proliferation and tumorigenesis of premalignant DCIS.COM human mammary epithelial cells. Breast Cancer Res. 2018;20:97 pubmed publisher
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| Bombassaro B, Ignacio Souza L, Nunez C, Razolli D, Pedro R, Coope A, et al. A20 deubiquitinase controls PGC-1? expression in the adipose tissue. Lipids Health Dis. 2018;17:90 pubmed publisher
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| Mouton Liger F, Rosazza T, Sepulveda Diaz J, Ieang A, Hassoun S, Claire E, et al. Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop. Glia. 2018;: pubmed publisher
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| Zhou Q, Wang H, Schwartz D, Stoffels M, Park Y, Zhang Y, et al. Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease. Nat Genet. 2016;48:67-73 pubmed publisher
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| Vande Walle L, Van Opdenbosch N, Jacques P, Fossoul A, Verheugen E, Vogel P, et al. Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis. Nature. 2014;512:69-73 pubmed publisher
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| Mc Guire C, Wieghofer P, Elton L, Muylaert D, Prinz M, Beyaert R, et al. Paracaspase MALT1 deficiency protects mice from autoimmune-mediated demyelination. J Immunol. 2013;190:2896-903 pubmed publisher
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| Sun J, Sun L, Zhang N, Lu X, Zhang H. A20 is up-regulated in primary mouse hepatocytes subjected to hypoxia and reperfusion. Cell Biochem Funct. 2012;30:683-6 pubmed publisher
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| Lippens S, Lefebvre S, Gilbert B, Sze M, Devos M, Verhelst K, et al. Keratinocyte-specific ablation of the NF-?B regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis. Cell Death Differ. 2011;18:1845-53 pubmed publisher
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