product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
PAR4 (A-10) Antibody
catalog :
sc-1666
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A-10
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; rat
Brandt J, Silveira L, Grassi T, Anselmo-Franci J, Fávaro W, Felisbino S, et al. Indole-3-carbinol attenuates the deleterious gestational effects of bisphenol A exposure on the prostate gland of male F1 rats. Reprod Toxicol. 2014;43:56-66 pubmed publisher
Ramos-Miguel A, García-Fuster M, Callado L, La Harpe R, Meana J, Garcia-Sevilla J. Phosphorylation of FADD (Fas-associated death domain protein) at serine 194 is increased in the prefrontal cortex of opiate abusers: relation to mitogen activated protein kinase, phosphoprotein enriched in astrocytes of 15 kDa, and Akt signaling pathways . Neuroscience. 2009;161:23-38 pubmed publisher
de Bessa Garcia S, Pereira M, Nagai M. Expression Pattern of the Pro-apoptotic Gene PAR-4 During the Morphogenesis of MCF-10A Human Mammary Epithelial Cells. Cancer Microenviron. 2010;4:33-8 pubmed
Franchitto A, Torrice A, Semeraro R, Napoli C, Nuzzo G, Giuliante F, et al. Prostate apoptosis response-4 is expressed in normal cholangiocytes, is down-regulated in human cholangiocarcinoma, and promotes apoptosis of neoplastic cholangiocytes when induced pharmacologically. Am J Pathol. 2010;177:1779-90 pubmed publisher
Casolari D, Pereira M, de Bessa Garcia S, Nagai M. Insulin-like growth factor-1 and 17β-estradiol down-regulate prostate apoptosis response-4 expression in MCF-7 breast cancer cells. Int J Mol Med. 2011;28:337-42 pubmed publisher
Garcia-Fuster M, Ramos-Miguel A, Miralles A, Garcia-Sevilla J. Opioid receptor agonists enhance the phosphorylation state of Fas-associated death domain (FADD) protein in the rat brain: functional interactions with casein kinase Ialpha, Galpha(i) proteins, and ERK1/2 signaling. Neuropharmacology. 2008;55:886-99 pubmed publisher
Revelos K, Petraki C, Gregorakis A, Scorilas A, Papanastasiou P, Koutsilieris M. Immunohistochemical expression of Bcl2 is an independent predictor of time-to-biochemical failure in patients with clinically localized prostate cancer following radical prostatectomy. Anticancer Res. 2005;25:3123-33 pubmed
Alvaro-Bartolomé M, La Harpe R, Callado L, Meana J, Garcia-Sevilla J. Molecular adaptations of apoptotic pathways and signaling partners in the cerebral cortex of human cocaine addicts and cocaine-treated rats. Neuroscience. 2011;196:1-15 pubmed publisher
Pereira M, de Bessa-Garcia S, Burikhanov R, Pavanelli A, Antunes L, Rangnekar V, et al. Prostate apoptosis response-4 is involved in the apoptosis response to docetaxel in MCF-7 breast cancer cells. Int J Oncol. 2013;43:531-8 pubmed publisher
Méndez-López L, Zapata-Benavides P, Zavala-Pompa A, Aguado-Barrera M, Pacheco-Calleros J, Rodriguez-Padilla C, et al. Immunohistochemical analysis of prostate apoptosis response-4 (Par-4) in Mexican women with breast cancer: a preliminary study. Arch Med Res. 2010;41:261-8 pubmed publisher
Donninger H, Hesson L, Vos M, Beebe K, Gordon L, Sidransky D, et al. The Ras effector RASSF2 controls the PAR-4 tumor suppressor. Mol Cell Biol. 2010;30:2608-20 pubmed publisher
Wang G, Silva J, Krishnamurthy K, Tran E, Condie B, Bieberich E. Direct binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cells. J Biol Chem. 2005;280:26415-24 pubmed
Nagai M, Gerhard R, Salaorni S, Fregnani J, Nonogaki S, Netto M, et al. Down-regulation of the candidate tumor suppressor gene PAR-4 is associated with poor prognosis in breast cancer. Int J Oncol. 2010;37:41-9 pubmed
product information
Product Name :
PAR4 (A-10) Antibody
Gene Name :
PAWR
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-1666
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
PAR4
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
FL (r)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
www.scbt.com
1.800.457.3801
headquarters: USA