product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
SLUG (A-7) Antibody
catalog :
sc-166476
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A-7
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:200; loading ...; fig 5a
Loureiro J, Raimundo L, Calheiros J, Carvalho C, Barcherini V, Lima N, et al. Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance. Cancers (Basel). 2021;13: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 5
Blasiak J, Koskela A, Pawlowska E, Liukkonen M, Ruuth J, Toropainen E, et al. Epithelial-Mesenchymal Transition and Senescence in the Retinal Pigment Epithelium of NFE2L2/PGC-1α Double Knock-Out Mice. Int J Mol Sci. 2021;22: pubmed publisher
  • western blot; mouse; loading ...; fig 4a
Comiskey D, Jacob A, Sanford B, Montes M, Goodwin A, Steiner H, et al. A novel mouse model of rhabdomyosarcoma underscores the dichotomy of MDM2-ALT1 function in vivo. Oncogene. 2018;37:95-106 pubmed publisher
  • western blot; human; 1:400; loading ...; fig 4d
Zangari J, Ilie M, Rouaud F, Signetti L, Ohanna M, Didier R, et al. Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition. Nucleic Acids Res. 2017;45:4131-4141 pubmed publisher
  • western blot; human; 1:200; loading ...; fig 5c
Liu S, Zhou F, Shen Y, Zhang Y, Yin H, Zeng Y, et al. Fluid shear stress induces epithelial-mesenchymal transition (EMT) in Hep-2 cells. Oncotarget. 2016;7:32876-92 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 2
Pickup M, Hover L, Guo Y, Gorska A, Chytil A, Novitskiy S, et al. Deletion of the BMP receptor BMPR1a impairs mammary tumor formation and metastasis. Oncotarget. 2015;6:22890-904 pubmed
  • immunohistochemistry - paraffin section; human; 1:100; fig 2
Mego M, Cierna Z, Janega P, Karaba M, Minarik G, Benca J, et al. Relationship between circulating tumor cells and epithelial to mesenchymal transition in early breast cancer. BMC Cancer. 2015;15:533 pubmed publisher
  • western blot; human; 1:500; fig 6c
Xu T, Fan B, Lv C, Xiao D. Slug mediates nasopharyngeal carcinoma radioresistance via downregulation of PUMA in a p53-dependent and -independent manner. Oncol Rep. 2015;33:2631-8 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 2d
Joseph J, Conroy S, Pavlov K, Sontakke P, Tomar T, Eggens Meijer E, et al. Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1α-ZEB1 axis. Cancer Lett. 2015;359:107-16 pubmed publisher
  • western blot; human; 1:500
Joseph J, Conroy S, Tomar T, Eggens Meijer E, Bhat K, Copray S, et al. TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion. Cell Death Dis. 2014;5:e1443 pubmed publisher
Wei C, Khan M, Du J, Cheng J, Tania M, Leung E, et al. Cordycepin Inhibits Triple-Negative Breast Cancer Cell Migration and Invasion by Regulating EMT-TFs SLUG, TWIST1, SNAIL1, and ZEB1. Front Oncol. 2022;12:898583 pubmed publisher
Zhang J, Fan X, Zhou Y, Chen L, Rao H. The PRMT5-LSD1 axis confers Slug dual transcriptional activities and promotes breast cancer progression. J Exp Clin Cancer Res. 2022;41:191 pubmed publisher
Kim H, Park M, Byun H, Kim M, Kim B, Yu L, et al. LW1497, an Inhibitor of Malate Dehydrogenase, Suppresses TGF-β1-Induced Epithelial-Mesenchymal Transition in Lung Cancer Cells by Downregulating Slug. Antioxidants (Basel). 2021;10: pubmed publisher
Chesnelong C, Hao X, Cseh O, Wang A, Luchman H, Weiss S. SLUG Directs the Precursor State of Human Brain Tumor Stem Cells. Cancers (Basel). 2019;11: pubmed publisher
Fenizia C, Bottino C, Corbetta S, Fittipaldi R, Floris P, Gaudenzi G, et al. SMYD3 promotes the epithelial-mesenchymal transition in breast cancer. Nucleic Acids Res. 2019;47:1278-1293 pubmed publisher
Chang C, Huang Y, Lin Y, Lin C, Jeng J, Liu S, et al. The role of sentrin-specific protease 2 substrate recognition in TGF-?-induced tumorigenesis. Sci Rep. 2018;8:9786 pubmed publisher
product information
Product Name :
SLUG (A-7) Antibody
Gene Name :
SNAI2
Size :
200 µg/ml
Catalog Number :
sc-166476
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
SLUG
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
21-160 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA