product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
JNK1 (F-3) Antibody
catalog :
sc-1648
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
F-3
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 30
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:100; loading ...; fig 7d
Patel M, Shah H, Shrivastava N. c-Myc-Dependent Cell Competition in Human Cancer Cells. J Cell Biochem. 2017;118:1782-1791 pubmed publisher
  • western blot; rat; 1:1000; fig 2
Prause M, Mayer C, Brorsson C, Frederiksen K, Billestrup N, Størling J, et al. JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression. J Diabetes Res. 2016;2016:1312705 pubmed publisher
  • western blot; rat; fig 3
Christensen D, Ejlerskov P, Rasmussen I, Vilhardt F. Reciprocal signals between microglia and neurons regulate α-synuclein secretion by exophagy through a neuronal cJUN-N-terminal kinase-signaling axis. J Neuroinflammation. 2016;13:59 pubmed publisher
  • western blot; mouse; fig 5
Liu S, Wu C, Huang K, Wang C, Guan S, Chen L, et al. C/EBP homologous protein (CHOP) deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease. Oncotarget. 2016;7:21900-12 pubmed publisher
  • western blot; human; fig 5A
Wang Z, Ma B, Li H, Xiao X, Zhou W, Liu F, et al. Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC. Oncotarget. 2016;7:509-23 pubmed publisher
  • western blot; human; loading ...; fig 9e
Hwang K, Choi Y. Modulation of Mitochondrial Antiviral Signaling by Human Herpesvirus 8 Interferon Regulatory Factor 1. J Virol. 2016;90:506-20 pubmed publisher
  • western blot; human
Cazanave S, Wang X, Zhou H, Rahmani M, Grant S, Durrant D, et al. Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis. Cell Death Differ. 2014;21:1303-12 pubmed publisher
  • western blot; human
Valente A, Irimpen A, Siebenlist U, Chandrasekar B. OxLDL induces endothelial dysfunction and death via TRAF3IP2: inhibition by HDL3 and AMPK activators. Free Radic Biol Med. 2014;70:117-28 pubmed publisher
  • western blot; human; loading ...; fig s1
Megison M, Gillory L, Stewart J, Nabers H, Mrozcek Musulman E, Beierle E. FAK inhibition abrogates the malignant phenotype in aggressive pediatric renal tumors. Mol Cancer Res. 2014;12:514-26 pubmed publisher
Walker N, Mazzoni S, Vittal R, Fingar D, Lama V. c-Jun N-terminal kinase (JNK)-mediated induction of mSin1 expression and mTORC2 activation in mesenchymal cells during fibrosis. J Biol Chem. 2018;293:17229-17239 pubmed publisher
Bartell S, Kim H, Ambrogini E, Han L, Iyer S, Serra Ucer S, et al. FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation. Nat Commun. 2014;5:3773 pubmed publisher
Farooq S, Boppana N, Devarajan A, Asokan D, Sekaran S, Shankar E, et al. C-phycocyanin confers protection against oxalate-mediated oxidative stress and mitochondrial dysfunctions in MDCK cells. PLoS ONE. 2014;9:e93056 pubmed publisher
Prause M, Christensen D, Billestrup N, Mandrup Poulsen T. JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis. PLoS ONE. 2014;9:e87067 pubmed publisher
Abid M, Chen J, Xiang M, Zhou J, Chen X, Gong F. Khat (Catha edulis) generates reactive oxygen species and promotes hepatic cell apoptosis via MAPK activation. Int J Mol Med. 2013;32:389-95 pubmed publisher
Semlali A, Witoled C, Alanazi M, Rouabhia M. Whole cigarette smoke increased the expression of TLRs, HBDs, and proinflammory cytokines by human gingival epithelial cells through different signaling pathways. PLoS ONE. 2012;7:e52614 pubmed publisher
Choi R, Ngoc T, Bae K, Cho H, Kim D, Chun J, et al. Anti-inflammatory properties of anthraquinones and their relationship with the regulation of P-glycoprotein function and expression. Eur J Pharm Sci. 2013;48:272-81 pubmed publisher
Parra E, Gutierrez L. Growth inhibition of Tax-activated human Jurkat leukemia T cells by all-trans retinoic acid requires JNK-1 inhibition. Oncol Rep. 2013;29:387-93 pubmed publisher
Wu N, Sulpice E, Obeïd P, Benzina S, Kermarrec F, Combe S, et al. The miR-17 family links p63 protein to MAPK signaling to promote the onset of human keratinocyte differentiation. PLoS ONE. 2012;7:e45761 pubmed publisher
Parra E. Inhibition of JNK-1 by small interfering RNA induces apoptotic signaling in PC-3 prostate cancer cells. Int J Mol Med. 2012;30:923-30 pubmed publisher
Stefani C, de Oliveira R, Silveira A, Ferraz L, Ribeiro M, Gambero A, et al. Expression of Toll-like receptors in enterocromaffin-like cells and their function in histamine release. Dig Dis Sci. 2012;57:2270-7 pubmed publisher
Sarró E, Jacobs Cachá C, Itarte E, Meseguer A. A pharmacologically-based array to identify targets of cyclosporine A-induced toxicity in cultured renal proximal tubule cells. Toxicol Appl Pharmacol. 2012;258:275-87 pubmed publisher
Liu H, Xiao Y, Xiong C, Wei A, Ruan J. Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation. Eur J Pharmacol. 2011;654:209-16 pubmed publisher
Parra E, Ferreira J. Knockdown of the c-Jun-N-terminal kinase expression by siRNA inhibits MCF-7 breast carcinoma cell line growth. Oncol Rep. 2010;24:1339-45 pubmed
Burkhard K, Shapiro P. Use of inhibitors in the study of MAP kinases. Methods Mol Biol. 2010;661:107-22 pubmed publisher
Nociari M, Ocheretina O, Murphy M, Falck Pedersen E. Adenovirus induction of IRF3 occurs through a binary trigger targeting Jun N-terminal kinase and TBK1 kinase cascades and type I interferon autocrine signaling. J Virol. 2009;83:4081-91 pubmed publisher
Li Y, Qian H, Li X, Wang H, Yu J, Liu Y, et al. Adenoviral-mediated gene transfer of Gadd45a results in suppression by inducing apoptosis and cell cycle arrest in pancreatic cancer cell. J Gene Med. 2009;11:3-13 pubmed publisher
Surgucheva I, Shestopalov V, Surguchov A. Effect of gamma-synuclein silencing on apoptotic pathways in retinal ganglion cells. J Biol Chem. 2008;283:36377-85 pubmed publisher
Lalioti V, Vergarajauregui S, Tsuchiya Y, Hernandez Tiedra S, Sandoval I. Daxx functions as a scaffold of a protein assembly constituted by GLUT4, JNK1 and KIF5B. J Cell Physiol. 2009;218:416-26 pubmed publisher
Rieber M, Rieber M. Mcl-1 cleavage and sustained phosphorylation of c-Jun-N-terminal kinase mediate melanoma apoptosis induced by 2-acetyl furanonaphthoquinone: roles of Bcl-2 and p53. Cancer Biol Ther. 2008;7:1206-11 pubmed
Yu J, Qian H, Li Y, Wang Y, Zhang X, Liang X, et al. Therapeutic effect of arsenic trioxide (As2O3) on cervical cancer in vitro and in vivo through apoptosis induction. Cancer Biol Ther. 2007;6:580-6 pubmed
product information
Product Name :
JNK1 (F-3) Antibody
Gene Name :
MAPK8
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-1648
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
JNK1
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P)
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA