product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
IkappaB-alpha (H-4) Antibody
catalog :
sc-1643
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H-4
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 67
Published Application/Species/Sample/Dilution | Reference |
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| Amigo Jiménez I, Bailón E, Aguilera Montilla N, GarcÃa Marco J, GarcÃa Pardo A. Gene expression profile induced by arsenic trioxide in chronic lymphocytic leukemia cells reveals a central role for heme oxygenase-1 in apoptosis and regulation of matrix metalloproteinase-9. Oncotarget. 2016;7:83359-83377 pubmed publisher
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| Amigo Jiménez I, Bailón E, Aguilera Montilla N, Terol M, GarcÃa Marco J, GarcÃa Pardo A. Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kδ or PKCβ signaling pathways. Oncotarget. 2015;6:44832-48 pubmed publisher
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| Neira Peña T, Rojas Mancilla E, Munoz Vio V, Perez R, Gutierrez Hernandez M, Bustamante D, et al. Perinatal asphyxia leads to PARP-1 overactivity, p65 translocation, IL-1β and TNF-α overexpression, and apoptotic-like cell death in mesencephalon of neonatal rats: prevention by systemic neonatal nicotinamide administration. Neurotox Res. 2015;27:453-65 pubmed publisher
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| Clauzure M, Valdivieso A, Massip Copiz M, Schulman G, Teiber M, Santa Coloma T. Disruption of interleukin-1? autocrine signaling rescues complex I activity and improves ROS levels in immortalized epithelial cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function. PLoS ONE. 2014;9:e99257 pubmed publisher
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Bhaskaran N, Shukla S, Srivastava J, Gupta S. Chamomile: an anti-inflammatory agent inhibits inducible nitric oxide synthase expression by blocking RelA/p65 activity. Int J Mol Med. 2010;26:935-40 pubmed
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Bhushan S, Malik F, Kumar A, Isher H, Kaur I, Taneja S, et al. Activation of p53/p21/PUMA alliance and disruption of PI-3/Akt in multimodal targeting of apoptotic signaling cascades in cervical cancer cells by a pentacyclic triterpenediol from Boswellia serrata. Mol Carcinog. 2009;48:1093-108 pubmed publisher
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Nunes E, Kuczera D, Brito G, Bonatto S, Yamazaki R, Tanhoffer R, et al. Beta-hydroxy-beta-methylbutyrate supplementation reduces tumor growth and tumor cell proliferation ex vivo and prevents cachexia in Walker 256 tumor-bearing rats by modifying nuclear factor-kappaB expression. Nutr Res. 2008;28:487-93 pubmed publisher
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Cai S, Brandt C. Induction of interleukin-6 in human retinal epithelial cells by an attenuated Herpes simplex virus vector requires viral replication and NFkappaB activation. Exp Eye Res. 2008;86:178-88 pubmed
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Kim H, Yoon D, Lee W, Han S, Shrestha B, Kim C, et al. Phellinus linteus inhibits inflammatory mediators by suppressing redox-based NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophage. J Ethnopharmacol. 2007;114:307-15 pubmed
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Feng G, Liu S, Wang G, Liu G. Lidocaine attenuates lipopolysaccharide-induced acute lung injury through inhibiting NF-kappaB activation. Pharmacology. 2008;81:32-40 pubmed
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Merling R, Chen C, Hong S, Zhang L, Liu M, Kuo Y, et al. HTLV-1 Tax mutants that do not induce G1 arrest are disabled in activating the anaphase promoting complex. Retrovirology. 2007;4:35 pubmed
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Zheng Z, Kim J, Ma H, Lee J, Yenari M. Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke. J Cereb Blood Flow Metab. 2008;28:53-63 pubmed
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Kim H, Yoon D, Kim C, Shrestha B, Chang W, Lim S, et al. Ethanol extract of Inonotus obliquus inhibits lipopolysaccharide-induced inflammation in RAW 264.7 macrophage cells. J Med Food. 2007;10:80-9 pubmed
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Romanatto T, Cesquini M, Amaral M, Roman E, Moraes J, Torsoni M, et al. TNF-alpha acts in the hypothalamus inhibiting food intake and increasing the respiratory quotient--effects on leptin and insulin signaling pathways. Peptides. 2007;28:1050-8 pubmed
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Chiu J, Chen L, Lee C, Lee P, Lee D, Tsai M, et al. Mechanisms of induction of endothelial cell E-selectin expression by smooth muscle cells and its inhibition by shear stress. Blood. 2007;110:519-28 pubmed
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Fernández Majada V, Aguilera C, Villanueva A, Vilardell F, Robert Moreno A, Aytes A, et al. Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer. Proc Natl Acad Sci U S A. 2007;104:276-81 pubmed
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Aguilera C, Fernández Majada V, Inglés Esteve J, Rodilla V, Bigas A, Espinosa L. Efficient nuclear export of p65-IkappaBalpha complexes requires 14-3-3 proteins. J Cell Sci. 2006;119:3695-704 pubmed
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Hanashiro K, Sunagawa M, Tokeshi Y, Nakasone T, Ohta S, Nakamura M, et al. Antiallergic drugs, azelastine hydrochloride and epinastine hydrochloride, inhibit ongoing IgE secretion of rat IgE-producing hybridoma FE-3 cells. Eur J Pharmacol. 2006;547:174-83 pubmed
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Wissel H, Burkhardt W, Rupp J, Wauer R, Rudiger M. Perfluorocarbons decrease Chlamydophila pneumoniae-mediated inflammatory responses of rat type II pneumocytes in vitro. Pediatr Res. 2006;60:264-9 pubmed
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Redondo Muñoz J, Escobar Díaz E, Samaniego R, Terol M, Garcia Marco J, Garcia Pardo A. MMP-9 in B-cell chronic lymphocytic leukemia is up-regulated by alpha4beta1 integrin or CXCR4 engagement via distinct signaling pathways, localizes to podosomes, and is involved in cell invasion and migration. Blood. 2006;108:3143-51 pubmed
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Goormachtigh G, Ouk T, Mougel A, Tranchand Bunel D, Masy E, Le Clorennec C, et al. Autoactivation of the Epstein-Barr virus oncogenic protein LMP1 during type II latency through opposite roles of the NF-kappaB and JNK signaling pathways. J Virol. 2006;80:7382-93 pubmed
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Ogino T, Hosako M, Hiramatsu K, Omori M, Ozaki M, Okada S. Oxidative modification of IkappaB by monochloramine inhibits tumor necrosis factor alpha-induced NF-kappaB activation. Biochim Biophys Acta. 2005;1746:135-42 pubmed
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Mun H, Aosai F, Norose K, Piao L, Fang H, Akira S, et al. Toll-like receptor 4 mediates tolerance in macrophages stimulated with Toxoplasma gondii-derived heat shock protein 70. Infect Immun. 2005;73:4634-42 pubmed
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Conde R, Xavier J, McLoughlin C, Chinkers M, Ovsenek N. Protein phosphatase 5 is a negative modulator of heat shock factor 1. J Biol Chem. 2005;280:28989-96 pubmed
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Yang J, Chen J, Luo L, Lin S, Li D, Hu S. Tetramethylpyrazine protected photoreceptor cells of rats by modulating nuclear translocation of NF-kappaB. Acta Pharmacol Sin. 2005;26:887-92 pubmed
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Dieckhoff K, Graf P, Beinhauer B, Schwaerzler C, Carballido J, Neumann C, et al. Deficient translocation of c-Rel is associated with impaired Th1 cytokine production in T cells from atopic dermatitis patients. Exp Dermatol. 2005;14:17-25 pubmed
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Löscher M, Fortschegger K, Ritter G, Wostry M, Voglauer R, Schmid J, et al. Interaction of U-box E3 ligase SNEV with PSMB4, the beta7 subunit of the 20 S proteasome. Biochem J. 2005;388:593-603 pubmed
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product information
Product Name :
IkappaB-alpha (H-4) Antibody
Gene Name :
NFKBIA
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-1643
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
IkappaB-alpha
reactive species :
m, r, h
Application :
WB, IP, IF, IHC(P), FCM, ELISA
Epitope :
1-317 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
more info or order :
company information

Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com1.800.457.3801
headquarters: USA
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