Published Application/Species/Sample/Dilution | Reference |
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- western blot; human; loading ...; fig 6A
| Chung C, Chang C, Hsu C, Lin K, Peng H, Huang T. Aggretin Venom Polypeptide as a Novel Anti-angiogenesis Agent by Targeting Integrin alpha2beta1. Sci Rep. 2017;7:43612 pubmed publisher
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- western blot; mouse; loading ...; fig 1e
| Sheen M, Marotti J, Allegrezza M, Rutkowski M, Conejo Garcia J, Fiering S. Constitutively activated PI3K accelerates tumor initiation and modifies histopathology of breast cancer. Oncogenesis. 2016;5:e267 pubmed publisher
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- western blot; mouse; loading ...; fig 1a
| Lakshmipathi J, Alvarez Perez J, Rosselot C, Casinelli G, Stamateris R, Rausell Palamos F, et al. PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2. Diabetes. 2016;65:1283-96 pubmed publisher
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- western blot; human; 1:200; fig 4
| Song G, Li Y, Lin L, Cao Y. Anti-autophagic and anti-apoptotic effects of memantine in a SH-SY5Y cell model of Alzheimer's disease via mammalian target of rapamycin-dependent and -independent pathways. Mol Med Rep. 2015;12:7615-22 pubmed publisher
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| Ito Y, Hart J, Ueno L, Vogt P. Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K). Proc Natl Acad Sci U S A. 2014;111:16826-9 pubmed publisher
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| Ren W, Duan J, Yin J, Liu G, Cao Z, Xiong X, et al. Dietary L-glutamine supplementation modulates microbial community and activates innate immunity in the mouse intestine. Amino Acids. 2014;46:2403-13 pubmed publisher
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| Kim K, Lee S, Ryu S, Han D. Efficient isolation and elution of cellular proteins using aptamer-mediated protein precipitation assay. Biochem Biophys Res Commun. 2014;448:114-9 pubmed publisher
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- western blot; mouse; fig 9
| Wu J, Akkuratov E, Bai Y, Gaskill C, Askari A, Liu L. Cell signaling associated with Na(+)/K(+)-ATPase: activation of phosphatidylinositide 3-kinase IA/Akt by ouabain is independent of Src. Biochemistry. 2013;52:9059-67 pubmed publisher
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| Luo J, Xu T, Li C, Ba X, Wang X, Jiang Y, et al. p85-RhoGDI2, a novel complex, is required for PSGL-1-induced ?1 integrin-mediated lymphocyte adhesion to VCAM-1. Int J Biochem Cell Biol. 2013;45:2764-73 pubmed publisher
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| Sollome J, Thavathiru E, Camenisch T, Vaillancourt R. HER2/HER3 regulates extracellular acidification and cell migration through MTK1 (MEKK4). Cell Signal. 2014;26:70-82 pubmed publisher
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- western blot; human; fig 3
| Chang C, Chen C, Wu M, Chen Y, Chen C, Sheu S, et al. Active Component of Antrodia cinnamomea Mycelia Targeting Head and Neck Cancer Initiating Cells through Exaggerated Autophagic Cell Death. Evid Based Complement Alternat Med. 2013;2013:946451 pubmed publisher
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| Shibata K, Kajiyama H, Ino K, Nawa A, Nomura S, Mizutani S, et al. P-LAP/IRAP-induced cell proliferation and glucose uptake in endometrial carcinoma cells via insulin receptor signaling. BMC Cancer. 2007;7:15 pubmed
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| Coffey J, Wang J, Smith M, Laing A, Bouchier Hayes D, Cotter T, et al. Phosphoinositide 3-kinase accelerates postoperative tumor growth by inhibiting apoptosis and enhancing resistance to chemotherapy-induced apoptosis. Novel role for an old enemy. J Biol Chem. 2005;280:20968-77 pubmed
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| Pedros C, Zhang Y, Hu J, Choi Y, Canonigo Balancio A, Yates J, et al. A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1. Nat Immunol. 2016;17:825-33 pubmed publisher
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| Di Zazzo E, Feola A, Zuchegna C, Romano A, Donini C, Bartollino S, et al. The p85 regulatory subunit of PI3K mediates cAMP-PKA and insulin biological effects on MCF-7 cell growth and motility. ScientificWorldJournal. 2014;2014:565839 pubmed publisher
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| Zhang J, Guo H, Zhu J, Yang Y, Chen W, Chen N. Inhibition of phosphoinositide 3-kinase/Akt pathway decreases hypoxia inducible factor-1? expression and increases therapeutic efficacy of paclitaxel in human hypoxic gastric cancer cells. Oncol Lett. 2014;7:1401-1408 pubmed
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| Oliveira Junior S, Martinez P, Guizoni D, Campos D, Fernandes T, Oliveira E, et al. AT1 receptor blockade attenuates insulin resistance and myocardial remodeling in rats with diet-induced obesity. PLoS ONE. 2014;9:e86447 pubmed publisher
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| Wang L, Xu S, Lee J, Baldridge A, Grullon S, Peng W, et al. Histone H3K9 methyltransferase G9a represses PPAR? expression and adipogenesis. EMBO J. 2013;32:45-59 pubmed publisher
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| Nadal Casellas A, Bauzá Thorbrügge M, Proenza A, Gianotti M, Llado I. Sex-dependent differences in rat brown adipose tissue mitochondrial biogenesis and insulin signaling parameters in response to an obesogenic diet. Mol Cell Biochem. 2013;373:125-35 pubmed publisher
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| Korkolopoulou P, Levidou G, Trigka E, Prekete N, Karlou M, Thymara I, et al. A comprehensive immunohistochemical and molecular approach to the PI3K/AKT/mTOR (phosphoinositide 3-kinase/v-akt murine thymoma viral oncogene/mammalian target of rapamycin) pathway in bladder urothelial carcinoma. BJU Int. 2012;110:E1237-48 pubmed publisher
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| Gupta R, Palchaudhuri S, Chattopadhyay D. Glutamate induces neutrophil cell migration by activating class I metabotropic glutamate receptors. Amino Acids. 2013;44:757-67 pubmed publisher
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| Guido C, Panza S, Santoro M, Avena P, Panno M, Perrotta I, et al. Estrogen receptor beta (ER?) produces autophagy and necroptosis in human seminoma cell line through the binding of the Sp1 on the phosphatase and tensin homolog deleted from chromosome 10 (PTEN) promoter gene. Cell Cycle. 2012;11:2911-21 pubmed publisher
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| D Cruz S, Jubendradass R, Jayakanthan M, Rani S, Mathur P. Bisphenol A impairs insulin signaling and glucose homeostasis and decreases steroidogenesis in rat testis: an in vivo and in silico study. Food Chem Toxicol. 2012;50:1124-33 pubmed publisher
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| Jubendradass R, D cruz S, Mathur P. Long-term exposure to nonylphenol affects insulin signaling in the liver of adult male rats. Hum Exp Toxicol. 2012;31:868-76 pubmed
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| Negri T, Brich S, Conca E, Bozzi F, Orsenigo M, Stacchiotti S, et al. Receptor tyrosine kinase pathway analysis sheds light on similarities between clear-cell sarcoma and metastatic melanoma. Genes Chromosomes Cancer. 2012;51:111-26 pubmed publisher
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| Caggia S, Libra M, Malaponte G, Cardile V. Modulation of YY1 and p53 expression by transforming growth factor-?3 in prostate cell lines. Cytokine. 2011;56:403-10 pubmed publisher
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| Gurney S, Forster P, Just U, Schwanbeck R. Suppression of the PI3K subunit p85? delays embryoid body development and inhibits cell adhesion. J Cell Biochem. 2011;112:3573-81 pubmed publisher
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| Padmanabhan R, Nirmala L, Murali M, Laloraya M. CrkL is a co-activator of estrogen receptor alpha that enhances tumorigenic potential in cancer. Mol Endocrinol. 2011;25:1499-512 pubmed publisher
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| Fortin C, Cloutier A, Ear T, Sylvain Prévost S, Mayer T, Bouchelaghem R, et al. A class IA PI3K controls inflammatory cytokine production in human neutrophils. Eur J Immunol. 2011;41:1709-19 pubmed publisher
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| Abou Youssif T, Fahmy M, Koumakpayi I, Ayala F, Al Marzooqi S, Chen G, et al. The mammalian target of rapamycin pathway is widely activated without PTEN deletion in renal cell carcinoma metastases. Cancer. 2011;117:290-300 pubmed publisher
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| Wang L, Jin Q, Lee J, Su I, Ge K. Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis. Proc Natl Acad Sci U S A. 2010;107:7317-22 pubmed publisher
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| Tamborini E, Virdis E, Negri T, Orsenigo M, Brich S, Conca E, et al. Analysis of receptor tyrosine kinases (RTKs) and downstream pathways in chordomas. Neuro Oncol. 2010;12:776-89 pubmed publisher
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| Moreno M, Ordonez P, Alonso A, Diaz F, Tolivia J, Gonzalez C. Chronic 17beta-estradiol treatment improves skeletal muscle insulin signaling pathway components in insulin resistance associated with aging. Age (Dordr). 2010;32:1-13 pubmed publisher
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| Torres V, Mielgo A, Barilà D, Anderson D, Stupack D. Caspase 8 promotes peripheral localization and activation of Rab5. J Biol Chem. 2008;283:36280-9 pubmed publisher
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| Raskopf E, Vogt A, Sauerbruch T, Schmitz V. siRNA targeting VEGF inhibits hepatocellular carcinoma growth and tumor angiogenesis in vivo. J Hepatol. 2008;49:977-84 pubmed publisher
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| Yano N, Suzuki D, Endoh M, Tseng A, Stabila J, McGonnigal B, et al. Beta-adrenergic receptor mediated protection against doxorubicin-induced apoptosis in cardiomyocytes: the impact of high ambient glucose. Endocrinology. 2008;149:6449-61 pubmed publisher
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| Derin D, Eralp Y, Ozluk Y, Yavuz E, Guney N, Saip P, et al. Lower level of MAPK expression is associated with anthracycline resistance and decreased survival in patients with hormone receptor negative breast cancer. Cancer Invest. 2008;26:671-9 pubmed publisher
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| Sato Y, Heuckeroth R. Retinoic acid regulates murine enteric nervous system precursor proliferation, enhances neuronal precursor differentiation, and reduces neurite growth in vitro. Dev Biol. 2008;320:185-98 pubmed publisher
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| He A, Zhu L, Gupta N, Chang Y, Fang F. Overexpression of micro ribonucleic acid 29, highly up-regulated in diabetic rats, leads to insulin resistance in 3T3-L1 adipocytes. Mol Endocrinol. 2007;21:2785-94 pubmed
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| Furuya F, Guigon C, Zhao L, Lu C, Hanover J, Cheng S. Nuclear receptor corepressor is a novel regulator of phosphatidylinositol 3-kinase signaling. Mol Cell Biol. 2007;27:6116-26 pubmed
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| Liu C, Yu I, Pan H, Lin S, Hsu H. L2dtl is essential for cell survival and nuclear division in early mouse embryonic development. J Biol Chem. 2007;282:1109-18 pubmed
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| Nakamura T, Terajima T, Ogata T, Ueno K, Hashimoto N, Ono K, et al. Establishment and pathophysiological characterization of type 2 diabetic mouse model produced by streptozotocin and nicotinamide. Biol Pharm Bull. 2006;29:1167-74 pubmed
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| Liu C, Lin S, Chen Y, Chang K, Chang K. Array-comparative genomic hybridization to detect genomewide changes in microdissected primary and metastatic oral squamous cell carcinomas. Mol Carcinog. 2006;45:721-31 pubmed
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| Noyce R, Collins S, Mossman K. Identification of a novel pathway essential for the immediate-early, interferon-independent antiviral response to enveloped virions. J Virol. 2006;80:226-35 pubmed
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