This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
C/EBP beta (C-19)
catalog :
sc-150
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, EMSA, chromatin immunoprecipitation, immunohistochemistry - paraffin section, ChIP-Seq, other
citations: 53
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; loading ...; fig s4d
Koike H, Zhang R, Ueno Y, Sekine K, Zheng Y, Takebe T, et al. Nutritional modulation of mouse and human liver bud growth through a branched-chain amino acid metabolism. Development. 2017;144:1018-1024 pubmed publisher
  • chromatin immunoprecipitation; mouse; loading ...; fig 4e
Mathew R, Tatarakis A, Rudenko A, Johnson Venkatesh E, Yang Y, Murphy E, et al. A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory. elife. 2016;5: pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 1e
  • immunocytochemistry; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 2e
Kuga T, Kume H, Adachi J, Kawasaki N, Shimizu M, Hoshino I, et al. Casein kinase 1 is recruited to nuclear speckles by FAM83H and SON. Sci Rep. 2016;6:34472 pubmed publisher
  • EMSA; human; fig s2a
Bigot P, Colli L, Machiela M, Jessop L, Myers T, Carrouget J, et al. Functional characterization of the 12p12.1 renal cancer-susceptibility locus implicates BHLHE41. Nat Commun. 2016;7:12098 pubmed publisher
  • western blot; mouse; loading ...; fig 1a
Jin J, Valanejad L, Nguyen T, Lewis K, Wright M, Cast A, et al. Activation of CDK4 Triggers Development of Non-alcoholic Fatty Liver Disease. Cell Rep. 2016;16:744-56 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 6c
  • western blot; human; 1:500; loading ...; fig 3d
Medler T, Craig J, Fiorillo A, Feeney Y, Harrell J, Clevenger C. HDAC6 Deacetylates HMGN2 to Regulate Stat5a Activity and Breast Cancer Growth. Mol Cancer Res. 2016;14:994-1008 pubmed
  • chromatin immunoprecipitation; human; loading ...; fig 4d
Zimmermann M, Arruda Silva F, Bianchetto Aguilera F, Finotti G, Calzetti F, Scapini P, et al. IFNα enhances the production of IL-6 by human neutrophils activated via TLR8. Sci Rep. 2016;6:19674 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3c
Wei W, Liu C, Qin D, Song L, Xia L, Lei H, et al. Targeting peroxiredoxin I potentiates 1,25-dihydroxyvitamin D3-induced cell differentiation in leukemia cells. Mol Med Rep. 2016;13:2201-7 pubmed publisher
  • ChIP-Seq; mouse; fig 1
Roe J, Mercan F, Rivera K, Pappin D, Vakoc C. BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia. Mol Cell. 2015;58:1028-39 pubmed publisher
  • western blot; human; loading ...; fig 3d
  • western blot; mouse; loading ...; fig 2a
Cai Y, Hirata A, Nakayama S, VanderLaan P, Levantini E, Yamamoto M, et al. CCAAT/enhancer binding protein β is dispensable for development of lung adenocarcinoma. PLoS ONE. 2015;10:e0120647 pubmed publisher
Reverte Salisa L, Siddig S, Hildebrand S, Yao X, Zurkovic J, Jaeckstein M, et al. EPAC1 enhances brown fat growth and beige adipogenesis. Nat Cell Biol. 2024;26:113-123 pubmed publisher
Shen Z, Li R, Prohaska T, Hoeksema M, Spann N, Tao J, et al. Systematic analysis of naturally occurring insertions and deletions that alter transcription factor spacing identifies tolerant and sensitive transcription factor pairs. elife. 2022;11: pubmed publisher
Sabatier M, Boet E, Zaghdoudi S, Guiraud N, Hucteau A, Polley N, et al. Activation of Vitamin D Receptor Pathway Enhances Differentiating Capacity in Acute Myeloid Leukemia with Isocitrate Dehydrogenase Mutations. Cancers (Basel). 2021;13: pubmed publisher
Merrett J, Bo T, Psaltis P, Proud C. Identification of DNA response elements regulating expression of CCAAT/enhancer-binding protein (C/EBP) β and δ and MAP kinase-interacting kinases during early adipogenesis. Adipocyte. 2020;9:427-442 pubmed publisher
Liu R, Xiong X, Nam D, Yechoor V, Ma K. SRF-MRTF signaling suppresses brown adipocyte development by modulating TGF-β/BMP pathway. Mol Cell Endocrinol. 2020;:110920 pubmed publisher
Lee J, Sung J, Choi E, Yoon H, Kang B, Hong E, et al. C/EBPβ Is a Transcriptional Regulator of Wee1 at the G₂/M Phase of the Cell Cycle. Cells. 2019;8: pubmed publisher
Xiong L, Wu F, Wu Q, Xu L, Cheung O, Kang W, et al. Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming. Nat Commun. 2019;10:335 pubmed publisher
Serresi M, Siteur B, Hulsman D, Company C, Schmitt M, Lieftink C, et al. Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities. J Exp Med. 2018;215:3115-3135 pubmed publisher
Larabee J, Hauck G, Ballard J. Unique, Intersecting, and Overlapping Roles of C/EBP β and CREB in Cells of the Innate Immune System. Sci Rep. 2018;8:16931 pubmed publisher
Messenger Z, Hall J, Jima D, House J, Tam H, Tokarz D, et al. C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event. Cell Death Dis. 2018;9:1054 pubmed publisher
Heinz S, Texari L, Hayes M, Urbanowski M, Chang M, Givarkes N, et al. Transcription Elongation Can Affect Genome 3D Structure. Cell. 2018;174:1522-1536.e22 pubmed publisher
Yu S, Zhu K, Chen J, Liu X, Xu P, Zhang W, et al. JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML. Nat Commun. 2018;9:3369 pubmed publisher
Cohen D, Lim H, Won K, Steger D. Shared nucleotide flanks confer transcriptional competency to bZip core motifs. Nucleic Acids Res. 2018;46:8371-8384 pubmed publisher
Qian K, Wang S, Fu M, Zhou J, Singh J, Li M, et al. Transcriptional regulation of O-GlcNAc homeostasis is disrupted in pancreatic cancer. J Biol Chem. 2018;293:13989-14000 pubmed publisher
Liu Y, Peng W, Guo Y, Liu Y, Tang Q, Guo L. Krüppel-like factor 10 (KLF10) is transactivated by the transcription factor C/EBPβ and involved in early 3T3-L1 preadipocyte differentiation. J Biol Chem. 2018;293:14012-14021 pubmed publisher
Dutta D, Lai K, Reyes Ordoñez A, Chen J, van der Donk W. Lanthionine synthetase C-like protein 2 (LanCL2) is important for adipogenic differentiation. J Lipid Res. 2018;59:1433-1445 pubmed publisher
Ramos Pittol J, Oruba A, Mittler G, Saccani S, van Essen D. Zbtb7a is a transducer for the control of promoter accessibility by NF-kappa B and multiple other transcription factors. PLoS Biol. 2018;16:e2004526 pubmed publisher
Link V, Duttke S, Chun H, Holtman I, Westin E, Hoeksema M, et al. Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function. Cell. 2018;173:1796-1809.e17 pubmed publisher
Bahrami Nejad Z, Zhao M, Tholen S, Hunerdosse D, Tkach K, van Schie S, et al. A Transcriptional Circuit Filters Oscillating Circadian Hormonal Inputs to Regulate Fat Cell Differentiation. Cell Metab. 2018;27:854-868.e8 pubmed publisher
Saito K, Takahashi K, Huang B, Asahara M, Kiso H, Togo Y, et al. Loss of Stemness, EMT, and Supernumerary Tooth Formation in Cebpb-/-Runx2+/- Murine Incisors. Sci Rep. 2018;8:5169 pubmed publisher
Mishra R, Benlhabib H, Guo W, Lerma Cervantes C, Mendelson C. Developmental Decline in the MicroRNA 199a (miR-199a)/miR-214 Cluster in Human Fetal Lung Promotes Type II Cell Differentiation by Upregulating Key Transcription Factors. Mol Cell Biol. 2018;38: pubmed publisher
Gabrielli M, Romero D, Martini C, Raiger Iustman L, Vila M. MCAM knockdown impairs PPARγ expression and 3T3-L1 fibroblasts differentiation to adipocytes. Mol Cell Biochem. 2018;448:299-309 pubmed publisher
Flanagan K, Alspach E, Pazolli E, Parajuli S, Ren Q, Arthur L, et al. c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors. Oncotarget. 2018;9:21-36 pubmed publisher
Rajbhandari P, Thomas B, Feng A, Hong C, Wang J, Vergnes L, et al. IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure. Cell. 2018;172:218-233.e17 pubmed publisher
Di Pascale F, Nama S, Muhuri M, Quah S, Ismail H, Chan X, et al. C/EBPβ mediates RNA polymerase III-driven transcription of oncomiR-138 in malignant gliomas. Nucleic Acids Res. 2018;46:336-349 pubmed publisher
Cao H, Zhang S, Shan S, Sun C, Li Y, Yu S, et al. Ligand-dependent corepressor (LCoR) represses the transcription factor C/EBPβ during early adipocyte differentiation. J Biol Chem. 2017;292:18973-18987 pubmed publisher
Ghosh S, Wallerath C, Covarrubias S, Hornung V, Carpenter S, Fitzgerald K. The PYHIN Protein p205 Regulates the Inflammasome by Controlling Asc Expression. J Immunol. 2017;199:3249-3260 pubmed publisher
Xu J, Xu X, Wang B, Ma Y, Zhang L, Xu H, et al. Nuclear carbonic anhydrase 6B associates with PRMT5 to epigenetically promote IL-12 expression in innate response. Proc Natl Acad Sci U S A. 2017;114:8620-8625 pubmed publisher
Roman T, Cannon M, Vadlamudi S, Buchkovich M, Wolford B, Welch R, et al. A Type 2 Diabetes-Associated Functional Regulatory Variant in a Pancreatic Islet Enhancer at the ADCY5 Locus. Diabetes. 2017;66:2521-2530 pubmed publisher
Lewis K, Valanejad L, Cast A, Wright M, Wei C, Iakova P, et al. RNA Binding Protein CUGBP1 Inhibits Liver Cancer in a Phosphorylation-Dependent Manner. Mol Cell Biol. 2017;37: pubmed publisher
Sahu S, Kumar M, Chakraborty S, Banerjee S, Kumar R, Gupta P, et al. MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling, the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection. PLoS Pathog. 2017;13:e1006410 pubmed publisher
Saleheen D, Zhao W, Young R, Nelson C, Ho W, Ferguson J, et al. Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions. Circulation. 2017;135:2336-2353 pubmed publisher
Zhang Y, Zhang L, Liu X, Zhao F, Ge C, Chen T, et al. Id4 promotes cell proliferation in hepatocellular carcinoma. Chin J Cancer. 2017;36:19 pubmed publisher
Guo W, Chen J, Yang Y, Zhu J, Wu J. Epigenetic programming of Dnmt3a mediated by AP2α is required for granting preadipocyte the ability to differentiate. Cell Death Dis. 2016;7:e2496 pubmed publisher
Brier A, Loft A, Madsen J, Rosengren T, Nielsen R, Schmidt S, et al. The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation. Nucleic Acids Res. 2017;45:1743-1759 pubmed publisher
Brenmoehl J, Ohde D, Albrecht E, Walz C, Tuchscherer A, Hoeflich A. Browning of subcutaneous fat and higher surface temperature in response to phenotype selection for advanced endurance exercise performance in male DUhTP mice. J Comp Physiol B. 2017;187:361-373 pubmed publisher
Hoare M, Ito Y, Kang T, Weekes M, Matheson N, Patten D, et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol. 2016;18:979-92 pubmed publisher
Dolfini D, Zambelli F, Pedrazzoli M, Mantovani R, Pavesi G. A high definition look at the NF-Y regulome reveals genome-wide associations with selected transcription factors. Nucleic Acids Res. 2016;44:4684-702 pubmed publisher
Marchildon F, Lamarche É, Lala Tabbert N, St Louis C, Wiper Bergeron N. Expression of CCAAT/Enhancer Binding Protein Beta in Muscle Satellite Cells Inhibits Myogenesis in Cancer Cachexia. PLoS ONE. 2015;10:e0145583 pubmed publisher
Ota A, Kovary K, Wu O, Ahrends R, Shen W, Costa M, et al. Using SRM-MS to quantify nuclear protein abundance differences between adipose tissue depots of insulin-resistant mice. J Lipid Res. 2015;56:1068-78 pubmed publisher
van der Krieken S, Popeijus H, Mensink R, Plat J. CCAAT/enhancer binding protein β in relation to ER stress, inflammation, and metabolic disturbances. Biomed Res Int. 2015;2015:324815 pubmed publisher
Alexander C, Selvarajan S, Mudgett J, Werb Z. Stromelysin-1 regulates adipogenesis during mammary gland involution. J Cell Biol. 2001;152:693-703 pubmed
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA