product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
GAPDH (A-3) Antibody
catalog :
sc-137179
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A-3
reactivity :
human, mouse, domestic horse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 71
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1c
Chen H, Padia R, Li T, Li Y, Li B, Jin L, et al. Signaling of MK2 sustains robust AP1 activity for triple negative breast cancer tumorigenesis through direct phosphorylation of JAB1. NPJ Breast Cancer. 2021;7:91 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4d
Wu X, Zhou H, Yue B, Li M, Liu F, Qiu C, et al. Upregulation of microRNA-25-3p inhibits proliferation, migration and invasion of osteosarcoma cells in vitro by directly targeting SOX4. Mol Med Rep. 2017;16:4293-4300 pubmed publisher
  • western blot; human; fig 1
Ling D, Chen Z, Liao Q, Feng J, Zhang X, Yin T. Differential effects of MTSS1 on invasion and proliferation in subtypes of non-small cell lung cancer cells. Exp Ther Med. 2016;12:1225-1231 pubmed
  • western blot; domestic horse; 1:1000; fig 1
Lee B, Kang H, Lee D, Ahn C, Jeung E. Claudin-1, -2, -4, and -5: comparison of expression levels and distribution in equine tissues. J Vet Sci. 2016;17:445-451 pubmed publisher
  • western blot; human; 1:1000; fig 5
Xi L, Schmidt J, Zaug A, Ascarrunz D, Cech T. A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression. Genome Biol. 2015;16:231 pubmed publisher
  • western blot; human; fig 7
Graindorge D, Martineau S, Machon C, Arnoux P, Guitton J, Francesconi S, et al. Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication. PLoS ONE. 2015;10:e0140645 pubmed publisher
  • western blot; human; fig 5
Granato M, Santarelli R, Filardi M, Gonnella R, Farina A, Torrisi M, et al. The activation of KSHV lytic cycle blocks autophagy in PEL cells. Autophagy. 2015;11:1978-1986 pubmed publisher
  • western blot; human; 1:1000; fig 3
Granato M, Gilardini Montani M, Filardi M, Faggioni A, Cirone M. Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppression. Oncotarget. 2015;6:29543-54 pubmed publisher
  • western blot; human; fig 7
Kennedy A, Vallurupalli M, Chen L, Crompton B, Cowley G, Vazquez F, et al. Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma. Oncotarget. 2015;6:30178-93 pubmed publisher
  • western blot; mouse; 1:10,000; fig s13
Fei Q, Yang X, Jiang H, Wang Q, Yu Y, Yu Y, et al. SETDB1 modulates PRC2 activity at developmental genes independently of H3K9 trimethylation in mouse ES cells. Genome Res. 2015;25:1325-35 pubmed publisher
  • western blot; human; 1:3000; loading ...; fig 6
Zhao Y, Xiao Z, Chen W, Yang J, Li T, Fan B. Disulfiram sensitizes pituitary adenoma cells to temozolomide by regulating O6-methylguanine-DNA methyltransferase expression. Mol Med Rep. 2015;12:2313-22 pubmed publisher
  • western blot; human; fig 2
Ji T, Guo Y, Kim K, McQueen P, Ghaffar S, Christ A, et al. Neuropilin-2 expression is inhibited by secreted Wnt antagonists and its down-regulation is associated with reduced tumor growth and metastasis in osteosarcoma. Mol Cancer. 2015;14:86 pubmed publisher
  • western blot; mouse
  • western blot; human
Cheng Y, Song L, Huang Y, Xiong Y, Zhang X, Sun H, et al. Effect of enterohaemorrhagic Escherichia coli O157:H7-specific enterohaemolysin on interleukin-1β production differs between human and mouse macrophages due to the different sensitivity of NLRP3 activation. Immunology. 2015;145:258-67 pubmed publisher
  • western blot; mouse; 1:2000
Li P, Ma X, Adams I, Yuan P. A tight control of Rif1 by Oct4 and Smad3 is critical for mouse embryonic stem cell stability. Cell Death Dis. 2015;6:e1588 pubmed publisher
  • western blot; human; fig 3
Hennig D, Müller S, Wichmann C, Drube S, Pietschmann K, Pelzl L, et al. Antagonism between granulocytic maturation and deacetylase inhibitor-induced apoptosis in acute promyelocytic leukaemia cells. Br J Cancer. 2015;112:329-37 pubmed publisher
  • western blot; mouse
Xu H, Zhou Y, Coughlan K, Ding Y, Wang S, Wu Y, et al. AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts. Biochim Biophys Acta. 2015;1853:65-73 pubmed publisher
  • western blot; human; 1:500
Vargas A, Zhou S, Ethier Chiasson M, Flipo D, Lafond J, Gilbert C, et al. Syncytin proteins incorporated in placenta exosomes are important for cell uptake and show variation in abundance in serum exosomes from patients with preeclampsia. FASEB J. 2014;28:3703-19 pubmed publisher
  • western blot; human
Birrane G, Li H, Yang S, Tachado S, Seng S. Cigarette smoke induces nuclear translocation of heme oxygenase 1 (HO-1) in prostate cancer cells: nuclear HO-1 promotes vascular endothelial growth factor secretion. Int J Oncol. 2013;42:1919-28 pubmed publisher
Hu R, Hameed U, Sun X, Moorthy B, Zhang W, Jeffrey P, et al. A NR2E1-interacting peptide of LSD1 inhibits the proliferation of brain tumour initiating cells. Cell Prolif. 2023;56:e13350 pubmed publisher
Palafox M, Monserrat L, Bellet M, Villacampa G, González Pérez A, Oliveira M, et al. High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer. Nat Commun. 2022;13:5258 pubmed publisher
Kajitani G, Brace L, Treviño Villarreal J, Trocha K, MacArthur M, Vose S, et al. Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model. Aging (Albany NY). 2021;13:22710-22731 pubmed publisher
Zhang D, Ning J, Okon I, Zheng X, Satyanarayana G, Song P, et al. Suppression of m6A mRNA modification by DNA hypermethylated ALKBH5 aggravates the oncological behavior of KRAS mutation/LKB1 loss lung cancer. Cell Death Dis. 2021;12:518 pubmed publisher
Vivarelli S, Falzone L, Ligresti G, Candido S, Garozzo A, Magro G, et al. Role of the Transcription Factor Yin Yang 1 and Its Selectively Identified Target Survivin in High-Grade B-Cells Non-Hodgkin Lymphomas: Potential Diagnostic and Therapeutic Targets. Int J Mol Sci. 2020;21: pubmed publisher
Gamerdinger M, Kobayashi K, Wallisch A, Kreft S, Sailer C, Schlömer R, et al. Early Scanning of Nascent Polypeptides inside the Ribosomal Tunnel by NAC. Mol Cell. 2019;75:996-1006.e8 pubmed publisher
Peng H, Yang F, Hu Q, Sun J, Peng C, Zhao Y, et al. The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity. Autophagy. 2019;:1-11 pubmed publisher
Voce D, Bernal G, Wu L, Crawley C, Zhang W, Mansour N, et al. Temozolomide Treatment Induces lncRNA MALAT1 in an NF-κB and p53 Codependent Manner in Glioblastoma. Cancer Res. 2019;79:2536-2548 pubmed publisher
Huang F, Huang S. Differential Effects of Statins on Inflammatory Interleukin-8 and Antimicrobial Peptide Human Β-Defensin 2 Responses in Salmonella-Infected Intestinal Epithelial Cells. Int J Mol Sci. 2018;19: pubmed publisher
Ottaviani S, Stebbing J, Frampton A, Zagorac S, Krell J, de Giorgio A, et al. TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression. Nat Commun. 2018;9:1845 pubmed publisher
Wojciechowski D, Thiemann S, Schaal C, Rahtz A, de la Roche J, Begemann B, et al. Activation of renal ClC-K chloride channels depends on an intact N terminus of their accessory subunit barttin. J Biol Chem. 2018;293:8626-8637 pubmed publisher
Huynh K, Jiang J, Abuladze N, Tsirulnikov K, Kao L, Shao X, et al. CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1. Nat Commun. 2018;9:900 pubmed publisher
Myers V, Tomar D, Madesh M, Wang J, Song J, Zhang X, et al. Haplo-insufficiency of Bcl2-associated athanogene 3 in mice results in progressive left ventricular dysfunction, β-adrenergic insensitivity, and increased apoptosis. J Cell Physiol. 2018;233:6319-6326 pubmed publisher
Pai P, Kuo C, Ho T, Lin J, Lin D, Tsai F, et al. p53-mediated miR-18 repression activates HSF2 for IGF-IIR-dependent myocyte hypertrophy in hypertension-induced heart failure. Cell Death Dis. 2017;8:e2990 pubmed publisher
Jung J, Ravi S, Lee D, McFadden K, Kamradt M, Toussaint L, et al. NIK/MAP3K14 Regulates Mitochondrial Dynamics and Trafficking to Promote Cell Invasion. Curr Biol. 2016;26:3288-3302 pubmed publisher
Lin S, Jiang T, Ye L, Han Z, Liu Y, Liu C, et al. The chromatin-remodeling enzyme BRG1 promotes colon cancer progression via positive regulation of WNT3A. Oncotarget. 2016;7:86051-86063 pubmed publisher
Zeng Y, Yao X, Chen L, Yan Z, Liu J, Zhang Y, et al. Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-β autocrine loop. Oncotarget. 2016;7:63324-63337 pubmed publisher
Zhuang Y, Dai J, Wang Y, Zhang H, Li X, Wang C, et al. MiR-338* suppresses fibrotic pathogenesis in pulmonary fibrosis through targeting LPA1. Am J Transl Res. 2016;8:3197-205 pubmed
Zhang Q, Giebler H, Isaacson M, Nyborg J. Eviction of linker histone H1 by NAP-family histone chaperones enhances activated transcription. Epigenetics Chromatin. 2015;8:30 pubmed publisher
Kotipatruni R, Ren X, Thotala D, Jaboin J. NDRG4 is a novel oncogenic protein and p53 associated regulator of apoptosis in malignant meningioma cells. Oncotarget. 2015;6:17594-604 pubmed
Song L, Huang Y, Zhao M, Wang Z, Wang S, Sun H, et al. A critical role for hemolysin in Vibrio fluvialis-induced IL-1β secretion mediated by the NLRP3 inflammasome in macrophages. Front Microbiol. 2015;6:510 pubmed publisher
Lee M, Venkitaraman A. A cancer-associated mutation inactivates a region of the high-mobility group protein HMG20b essential for cytokinesis. Cell Cycle. 2014;13:2554-63 pubmed publisher
Bradshaw N, Bader V, Prikulis I, Lueking A, Müllner S, Korth C. Aggregation of the protein TRIOBP-1 and its potential relevance to schizophrenia. PLoS ONE. 2014;9:e111196 pubmed publisher
Patwardhan G, Hosain S, Liu D, Khiste S, Zhao Y, Bielawski J, et al. Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells. Biochim Biophys Acta. 2014;1841:1571-80 pubmed publisher
Voce D, Schmitt A, Uppal A, McNerney M, Bernal G, Cahill K, et al. Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor. Oncogene. 2015;34:2807-13 pubmed publisher
Schwartz J, Podell E, Han S, Berry J, EGGAN K, Cech T. FUS is sequestered in nuclear aggregates in ALS patient fibroblasts. Mol Biol Cell. 2014;25:2571-8 pubmed publisher
Wu Q, Kohli M, Bergen H, Cheville J, Karnes R, Cao H, et al. Preclinical evaluation of the supercritical extract of azadirachta indica (neem) leaves in vitro and in vivo on inhibition of prostate cancer tumor growth. Mol Cancer Ther. 2014;13:1067-77 pubmed publisher
Santarelli R, Gonnella R, Di Giovenale G, Cuomo L, Capobianchi A, Granato M, et al. STAT3 activation by KSHV correlates with IL-10, IL-6 and IL-23 release and an autophagic block in dendritic cells. Sci Rep. 2014;4:4241 pubmed publisher
Li P, Chen Y, Mak K, Wong C, Wang C, Yuan P. Functional role of Mst1/Mst2 in embryonic stem cell differentiation. PLoS ONE. 2013;8:e79867 pubmed publisher
Liu Q, Wang X. Effect of TRPV2 cation channels on the proliferation, migration and invasion of 5637 bladder cancer cells. Exp Ther Med. 2013;6:1277-1282 pubmed
Nayak R, Bernal W, Lee J, Kearns M, Cheung V. Stress-induced changes in gene interactions in human cells. Nucleic Acids Res. 2014;42:1757-71 pubmed publisher
Huang N, Singh N, Yoon K, Loiacono C, Kohut M, Birt D. The immuno-regulatory impact of orally-administered Hypericum perforatum extract on Balb/C mice inoculated with H1n1 influenza A virus. PLoS ONE. 2013;8:e76491 pubmed publisher
Hofmeister Brix A, Lenzen S, Baltrusch S. The ubiquitin-proteasome system regulates the stability and activity of the glucose sensor glucokinase in pancreatic β-cells. Biochem J. 2013;456:173-84 pubmed publisher
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Lee Y, Stachowiak E, Birkaya B, Terranova C, Capacchietti M, Claus P, et al. NGF-induced cell differentiation and gene activation is mediated by integrative nuclear FGFR1 signaling (INFS). PLoS ONE. 2013;8:e68931 pubmed publisher
Granato M, Lacconi V, Peddis M, Lotti L, di Renzo L, Renzo L, et al. HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma. Cell Death Dis. 2013;4:e730 pubmed publisher
Courjaret R, Hubrack S, Daalis A, Dib M, Machaca K. The Xenopus TRPV6 homolog encodes a Mg(2+) -permeant channel that is inhibited by interaction with TRPC1. J Cell Physiol. 2013;228:2386-98 pubmed publisher
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Duan X, Mao X, Sun W. ADAM15 is involved in MICB shedding and mediates the effects of gemcitabine on MICB shedding in PANC-1 pancreatic cancer cells. Mol Med Rep. 2013;7:991-7 pubmed publisher
Yang Y, Yang H, Wang Z, Mergler S, Wolosin J, Reinach P. Functional TRPV1 expression in human corneal fibroblasts. Exp Eye Res. 2013;107:121-9 pubmed publisher
Zhang X, Cheng Y, Xiong Y, Ye C, Zheng H, Sun H, et al. Enterohemorrhagic Escherichia coli specific enterohemolysin induced IL-1? in human macrophages and EHEC-induced IL-1? required activation of NLRP3 inflammasome. PLoS ONE. 2012;7:e50288 pubmed publisher
Wei N, Zhang L, Huang H, Chen Y, Zheng J, Zhou X, et al. siRNA has greatly elevated mismatch tolerance at 3'-UTR sites. PLoS ONE. 2012;7:e49309 pubmed publisher
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product information
Catalog Number :
sc-137179
Product Name :
GAPDH (A-3) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
A-3
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
GAPDH
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA