product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Sigma Receptor (B-5) Antibody
catalog :
sc-137075
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-5
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry knockout validation
citations: 12
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; fig 2
Mavlyutov T, Duellman T, Kim H, Epstein M, Leese C, Davletov B, et al. Sigma-1 receptor expression in the dorsal root ganglion: Reexamination using a highly specific antibody. Neuroscience. 2016;331:148-57 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig s5a
Wheeler M, Jaronen M, Covacu R, Zandee S, Scalisi G, Rothhammer V, et al. Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation. Cell. 2019;176:581-596.e18 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 5c
Niu F, Liao K, Hu G, Sil S, Callen S, Guo M, et al. Cocaine-induced release of CXCL10 from pericytes regulates monocyte transmigration into the CNS. J Cell Biol. 2019;218:700-721 pubmed publisher
  • western blot; mouse; 1:1000
Sánchez Fernández C, Montilla García Á, González Cano R, Nieto F, Romero L, Artacho Cordón A, et al. Modulation of peripheral ?-opioid analgesia by ?1 receptors. J Pharmacol Exp Ther. 2014;348:32-45 pubmed publisher
Song L, Bekdash R, Morikawa K, Quejada J, Klein A, Aina Badejo D, et al. Sigma non-opioid receptor 1 is a potential therapeutic target for long QT syndrome. Nat Cardiovasc Res. 2022;1:142-156 pubmed publisher
Liu W, Ma Z, Wu Y, Yuan C, Zhang Y, Liang Z, et al. MST4 negatively regulates type I interferons production via targeting MAVS-mediated pathway. Cell Commun Signal. 2022;20:103 pubmed publisher
Barwick S, Siddiq M, Wang J, Xiao H, Marshall B, Perry E, et al. Sigma 1 Receptor Co-Localizes with NRF2 in Retinal Photoreceptor Cells. Antioxidants (Basel). 2021;10: pubmed publisher
Ryskamp D, Zhemkov V, Bezprozvanny I. Mutational Analysis of Sigma-1 Receptor's Role in Synaptic Stability. Front Neurosci. 2019;13:1012 pubmed publisher
Ryskamp D, Wu L, Wu J, Kim D, Rammes G, Geva M, et al. Pridopidine stabilizes mushroom spines in mouse models of Alzheimer's disease by acting on the sigma-1 receptor. Neurobiol Dis. 2019;124:489-504 pubmed publisher
Entrena J, Sánchez Fernández C, Nieto F, González Cano R, Yeste S, Cobos E, et al. Sigma-1 Receptor Agonism Promotes Mechanical Allodynia After Priming the Nociceptive System with Capsaicin. Sci Rep. 2016;6:37835 pubmed publisher
Ryskamp D, Wu J, Geva M, Kusko R, Grossman I, Hayden M, et al. The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington disease. Neurobiol Dis. 2017;97:46-59 pubmed publisher
Navarro G, Moreno E, Bonaventura J, Brugarolas M, Farré D, Aguinaga D, et al. Cocaine inhibits dopamine D2 receptor signaling via sigma-1-D2 receptor heteromers. PLoS ONE. 2013;8:e61245 pubmed publisher
product information
Catalog Number :
sc-137075
Product Name :
Sigma Receptor (B-5) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
B-5
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Sigma Receptor
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA