product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Heme Oxygenase 1 (A-3) Antibody
catalog :
sc-136960
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A-3
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 32
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; rat; loading ...; fig 5f
Muhammad A, Hao L, Al Kury L, Rehman N, Alvi A, Badshah H, et al. Carveol Promotes Nrf2 Contribution in Depressive Disorders through an Anti-inflammatory Mechanism. Oxid Med Cell Longev. 2022;2022:4509204 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 3c
  • western blot; human; 1:1000; loading ...; fig 4a, s5b
Zerfaoui M, Toraih E, Ruiz E, Errami Y, Attia A, Krzysztof M, et al. Nuclear Localization of BRAFV600E Is Associated with HMOX-1 Upregulation and Aggressive Behavior of Melanoma Cells. Cancers (Basel). 2022;14: pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:100; loading ...; fig 6d
Alvi A, Al Kury L, Alattar A, Ullah I, Muhammad A, Alshaman R, et al. Carveol Attenuates Seizure Severity and Neuroinflammation in Pentylenetetrazole-Kindled Epileptic Rats by Regulating the Nrf2 Signaling Pathway. Oxid Med Cell Longev. 2021;2021:9966663 pubmed publisher
  • western blot; mouse; fig 6b
Tao S, Yang Y, Li J, Wang H, Ma Y. Bixin Attenuates High-Fat Diet-Caused Liver Steatosis and Inflammatory Injury through Nrf2/PPARα Signals. Oxid Med Cell Longev. 2021;2021:6610124 pubmed publisher
  • western blot; rat; loading ...; fig 3c
Rafikova O, James J, Eccles C, Kurdyukov S, Niihori M, Varghese M, et al. Early progression of pulmonary hypertension in the monocrotaline model in males is associated with increased lung permeability. Biol Sex Differ. 2020;11:11 pubmed publisher
  • western blot; mouse; 1:300; loading ...; fig 4g
Chen X, Zhao Y, Xu J, Bao J, Zhao J, Chen J, et al. The Nephroprotective Effect of TNF Receptor-Associated Factor 6 (TRAF6) Blockade on LPS-Induced Acute Renal Injury Through the Inhibition if Inflammation and Oxidative Stress. Med Sci Monit. 2020;26:e919698 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 6a
Duan W, Chen J, Wu Y, Zhang Y, Xu Y. Protective effect of higenamine ameliorates collagen-induced arthritis through heme oxygenase-1 and PI3K/Akt/Nrf-2 signaling pathways. Exp Ther Med. 2016;12:3107-3112 pubmed
  • immunocytochemistry; human; 1:50
Dugmonits K, Ferencz A, Zahorán S, Lázár R, Talapka P, Orvos H, et al. Elevated levels of macromolecular damage are correlated with increased nitric oxide synthase expression in erythrocytes isolated from twin neonates. Br J Haematol. 2016;174:932-41 pubmed publisher
  • immunohistochemistry; rat; 1:300; fig 4
Qiao Y, Guo W, Li L, Shao S, Qiao X, Shao J, et al. Melatonin attenuates hypertension-induced renal injury partially through inhibiting oxidative stress in rats. Mol Med Rep. 2016;13:21-6 pubmed publisher
  • western blot; mouse; fig 7
Pajaud J, Ribault C, Ben Mosbah I, Rauch C, Henderson C, Bellaud P, et al. Glutathione transferases P1/P2 regulate the timing of signaling pathway activations and cell cycle progression during mouse liver regeneration. Cell Death Dis. 2015;6:e1598 pubmed publisher
Beltzig L, Schwarzenbach C, Leukel P, Frauenknecht K, Sommer C, Tancredi A, et al. Senescence Is the Main Trait Induced by Temozolomide in Glioblastoma Cells. Cancers (Basel). 2022;14: pubmed publisher
Przepiorski A, Vanichapol T, Espiritu E, Crunk A, Parasky E, McDaniels M, et al. Modeling oxidative injury response in human kidney organoids. Stem Cell Res Ther. 2022;13:76 pubmed publisher
Hsu M, Hsiao Y, Lin Y, Chen C, Lee C, Liao W, et al. Quercetin Alleviates the Accumulation of Superoxide in Sodium Iodate-Induced Retinal Autophagy by Regulating Mitochondrial Reactive Oxygen Species Homeostasis through Enhanced Deacetyl-SOD2 via the Nrf2-PGC-1α-Sirt1 Pathway. Antioxidants (Basel). 2021;10: pubmed publisher
D Amico R, Trovato Salinaro A, Cordaro M, Fusco R, Impellizzeri D, Interdonato L, et al. Hidrox® and Chronic Cystitis: Biochemical Evaluation of Inflammation, Oxidative Stress, and Pain. Antioxidants (Basel). 2021;10: pubmed publisher
Fusco R, Salinaro A, Siracusa R, D Amico R, Impellizzeri D, Scuto M, et al. Hidrox® Counteracts Cyclophosphamide-Induced Male Infertility through NRF2 Pathways in a Mouse Model. Antioxidants (Basel). 2021;10: pubmed publisher
Yan J, Huang J, Liu A, Wu J, Fan H, Shen M, et al. Atorvastatin improves motor function, anxiety and depression by NOX2-mediated autophagy and oxidative stress in MPTP-lesioned mice. Aging (Albany NY). 2020;13:831-845 pubmed publisher
Cordaro M, Fusco R, D Amico R, Siracusa R, Peritore A, Gugliandolo E, et al. Cashew (Anacardium occidentale L.) Nuts Modulate the Nrf2 and NLRP3 Pathways in Pancreas and Lung after Induction of Acute Pancreatitis by Cerulein. Antioxidants (Basel). 2020;9: pubmed publisher
Zhang G, Kai J, Chen M, Ma Q, Zhong A, Xie S, et al. Downregulation of XBP1 decreases serous ovarian cancer cell viability and enhances sensitivity to oxidative stress by increasing intracellular ROS levels. Oncol Lett. 2019;18:4194-4202 pubmed publisher
Rushing A, Rushing B, Hoang K, Sanders S, Peloponese J, Polakowski N, et al. HTLV-1 basic leucine zipper factor protects cells from oxidative stress by upregulating expression of Heme Oxygenase I. PLoS Pathog. 2019;15:e1007922 pubmed publisher
Zhou L, Ouyang R, Luo H, Peng Y, Chen P, Ren S, et al. Dysfunction of Nrf2-ARE Signaling Pathway: Potential Pathogenesis in the Development of Neurocognitive Impairment in Patients with Moderate to Severe Obstructive Sleep Apnea-Hypopnea Syndrome. Oxid Med Cell Longev. 2018;2018:3529709 pubmed publisher
Zhao X, Yu H, Yang Y, Wu W, Chen T, Jia K, et al. Polydatin prevents fructose-induced liver inflammation and lipid deposition through increasing miR-200a to regulate Keap1/Nrf2 pathway. Redox Biol. 2018;18:124-137 pubmed publisher
Erdei J, Tóth A, Balogh E, Nyakundi B, Bányai E, Ryffel B, et al. Induction of NLRP3 Inflammasome Activation by Heme in Human Endothelial Cells. Oxid Med Cell Longev. 2018;2018:4310816 pubmed publisher
Onodera Y, Teramura T, Takehara T, Obora K, Mori T, Fukuda K. miR-155 induces ROS generation through downregulation of antioxidation-related genes in mesenchymal stem cells. Aging Cell. 2017;16:1369-1380 pubmed publisher
Bui A, Huang M, Havard M, Laurent Tchenio F, Dautry F, Tchenio T. Transient exposure to androgens induces a remarkable self-sustained quiescent state in dispersed prostate cancer cells. Cell Cycle. 2017;16:879-893 pubmed publisher
Kwon Y, Cheon S, Park S, Song J, Lee J. Tryptanthrin Suppresses the Activation of the LPS-Treated BV2 Microglial Cell Line via Nrf2/HO-1 Antioxidant Signaling. Front Cell Neurosci. 2017;11:18 pubmed publisher
Xi M, Sun Z, Sun H, Jia J, Jiang Z, Tao L, et al. Synthesis and bioevaluation of a series of ?-pyrone derivatives as potent activators of Nrf2/ARE pathway (part I). Eur J Med Chem. 2013;66:364-71 pubmed publisher
Zhao R, Yang B, Wang L, Xue P, Deng B, Zhang G, et al. Curcumin protects human keratinocytes against inorganic arsenite-induced acute cytotoxicity through an NRF2-dependent mechanism. Oxid Med Cell Longev. 2013;2013:412576 pubmed publisher
Atif F, Yousuf S, Sayeed I, Ishrat T, Hua F, Stein D. Combination treatment with progesterone and vitamin D hormone is more effective than monotherapy in ischemic stroke: the role of BDNF/TrkB/Erk1/2 signaling in neuroprotection. Neuropharmacology. 2013;67:78-87 pubmed publisher
Yuan L, Wang J, Xiao H, Xiao C, Wang Y, Liu X. Isoorientin induces apoptosis through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway in HepG2 cancer cells. Toxicol Appl Pharmacol. 2012;265:83-92 pubmed publisher
Bhaskaran N, Shukla S, Kanwal R, Srivastava J, Gupta S. Induction of heme oxygenase-1 by chamomile protects murine macrophages against oxidative stress. Life Sci. 2012;90:1027-33 pubmed publisher
Pozzesi N, Pierangeli S, Vacca C, Falchi L, Pettorossi V, Martelli M, et al. Maesopsin 4-O-beta-D-glucoside, a natural compound isolated from the leaves of Artocarpus tonkinensis, inhibits proliferation and up-regulates HMOX1, SRXN1 and BCAS3 in acute myeloid leukemia. J Chemother. 2011;23:150-7 pubmed
Wang C, Hu F, Guo S, Mi D, Shen W, Zhang J, et al. BMP-6 inhibits MMP-9 expression by regulating heme oxygenase-1 in MCF-7 breast cancer cells. J Cancer Res Clin Oncol. 2011;137:985-95 pubmed publisher
product information
Catalog Number :
sc-136960
Product Name :
Heme Oxygenase 1 (A-3) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
A-3
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Heme Oxygenase 1
Specificity :
human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA