product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
NHE-1 (54) Antibody
catalog :
sc-136239
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
54
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:100; loading ...; fig 1g
Toft N, Axelsen T, Pedersen H, Mele M, Burton M, Balling E, et al. Acid-base transporters and pH dynamics in human breast carcinomas predict proliferative activity, metastasis, and survival. elife. 2021;10: pubmed publisher
  • immunohistochemistry; human; 1:100; loading ...; fig 1g
Kayyal H, Chandran S, Yiannakas A, Gould N, Khamaisy M, Rosenblum K. Insula to mPFC reciprocal connectivity differentially underlies novel taste neophobic response and learning in mice. elife. 2021;10: pubmed publisher
  • western blot; human; fig 4a
Heider M, Eichner R, Stroh J, Morath V, Kuisl A, Zecha J, et al. The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma. Mol Cell. 2021;: pubmed publisher
  • flow cytometry; mouse
Hasan M, Luo L, Ding D, Song S, Bhuiyan M, Liu R, et al. Blocking NHE1 stimulates glioma tumor immunity by restoring OXPHOS function of myeloid cells. Theranostics. 2021;11:1295-1309 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 3a
Castella B, Kopecka J, Sciancalepore P, Mandili G, Foglietta M, Mitro N, et al. The ATP-binding cassette transporter A1 regulates phosphoantigen release and Vγ9Vδ2 T cell activation by dendritic cells. Nat Commun. 2017;8:15663 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 2
  • immunocytochemistry; human; fig 2
  • western blot; human; fig 3
Andersen A, Flinck M, Oernbo E, Pedersen N, Viuff B, Pedersen S. Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment. Mol Cancer. 2016;15:45 pubmed publisher
  • western blot; human
Lee S, Mele M, Vahl P, Christiansen P, Jensen V, Boedtkjer E. Na+,HCO3- -cotransport is functionally upregulated during human breast carcinogenesis and required for the inverted pH gradient across the plasma membrane. Pflugers Arch. 2015;467:367-77 pubmed publisher
Zhang Y, Li Y, Thompson K, Stoletov K, Yuan Q, Bera K, et al. Polarized NHE1 and SWELL1 regulate migration direction, efficiency and metastasis. Nat Commun. 2022;13:6128 pubmed publisher
Bensimon A, Pizzagalli M, Kartnig F, Dvorak V, Essletzbichler P, Winter G, et al. Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis. Cell Chem Biol. 2020;27:728-739.e9 pubmed publisher
Veland I, Montjean R, Eley L, Pedersen L, Schwab A, Goodship J, et al. Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration. PLoS ONE. 2013;8:e60193 pubmed publisher
Danielsen A, Parker M, Lee S, Boron W, Aalkjaer C, Boedtkjer E. Splice cassette II of Na+,HCO3(-) cotransporter NBCn1 (slc4a7) interacts with calcineurin A: implications for transporter activity and intracellular pH control during rat artery contractions. J Biol Chem. 2013;288:8146-55 pubmed publisher
product information
Catalog Number :
sc-136239
Product Name :
NHE-1 (54) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
54
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
NHE-1
Specificity :
mouse, rat, human
Uses :
WB, IP, IF
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA